Clinical values of different specimen preparation methods for the diagnosis of lung cancer by EBUS-TBNA

Diagnostic Pathology

Table 2 Comparison of the diagnostic positive rates of histopathology, TSC and LBC in the diagnosis of LNs specimen (n = 213)

	Positive, n (%)	Negative, n (%)	Diagnostic positive rate, n (%)	χ²	p value
HP	72.3(154)	27.7(59) ^a	72.3 (154)
TSC	69.0(147) ^b	31.0(66) ^c	69.0 (147)
LBC	65.7(140) ^d	34.3(73) ^e	65.7 (140)	2.152^#	0.341^#
HP + TSC	78.9(168) ^b	21.1(45) ^f	78.9 (168)	9.874^##	0.020^##
HP + LBC	77.0(164) ^d	23.0(49) ^g	77.0 (164)	7.178^###	0.066^###
HP + TSC + LBC	81.2(173) ^h	18.8(40) ^k	81.2 (173)	1.152^*, 14.11^&	0.562^*,0.003^&
Final diagnosis	81.2(173)	18.8(40)	81.2 (173)

Abbreviations; HP = Histopathology, TSC = Traditional smear cytology, LBC = Liquid-based cytology
^a including 19 LNs of false negative diagnosis; ^b including 2 LNs of false positive diagnosis; ^c including 28 LNs of false negative diagnosis; ^d including 1 LN of false positive diagnosis; ^e including 34 LNs of false negative diagnosis; ^f including 6 LNs of false negative diagnosis; ^g including 9 LNs of false negative diagnosis; ^h including 3 LNs of false positive diagnosis; ^k including 3 LNs of false negative diagnosis
^#Comparison of diagnostic positive rates among HP, TSC and LBC; ^##Comparison of diagnostic positive rates between combination of the two specimen preparation methods (HP + TSC) and any single specimen preparation method; ^### Comparison of diagnostic positive rates between combination of the two specimen preparation methods (HP + LBC) and any single specimen preparation method
^*Comparison of diagnostic positive rates among combination of the three specimen preparation methods and combination of the two specimen preparation methods; ^&Comparison of diagnostic positive rates between combination of the three specimen preparation methods and any single specimen preparation method

ISSN: 1746-1596