Table 1 Summary of characteristics of dorsal tongue SCC in previous reported cases and the present series
| Â | Age (y)/ Sex | Medical history | Tobacco history | Histology | TP53 mutations | p53 IHC |
|---|---|---|---|---|---|---|
Yamasaki et al. [19] | 69/M | Esophageal, gastric, and renal cancer | Former smoker | Well-differentiated SCC | Germline p.R280* | Null |
Abe et al. [20] | 69/F | No | No | Well-differentiated SCC | NA | Positive |
Case 1 | 63/F | No | Former smoker 40 pack-years | Well-differentiated SCC | No | WT |
Case 2 | 74/M | Urothelial cancer | Current smoker 5 pack-years or more | Well-differentiated SCC | No | WT |
Case 3 | 63/M | MDS | No | Verrucous carcinoma with dysplasia or minimal invasion (well-differentiated SCC) | Somatic p.C176F | WT |
Case 4 | 15/M | IBMFS | No | Well-differentiated SCC | Somatic p.R282W | Positive |