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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  2. Karyopherin α2 (KPNA2), a member of the karyopherin α family, has been studied in several cancers but has not yet been substantially investigated in malignant bone tumors. The purpose of the current study was ...

    Authors: Lucen Jiang, Jianghuan Liu, Qingzhu Wei and Yiyang Wang
    Citation: Diagnostic Pathology 2020 15:135
    Content type: Research Published on:

  3. Pulmonary NUT carcinoma is rare, but lethal, thus, must not be overlooked. The definitive diagnosis is made by a NUT monoclonal antibody or gene analysis, but these are not always routinely available. Therefor...

    Authors: Satoe Numakura, Koji Saito, Noriko Motoi, Taisuke Mori, Yuichi Saito, Fumi Yokote, Yasuyuki Kanamoto, Momoko Asami, Takashi Sakai, Yoshikane Yamauchi, Yukinori Sakao, Hiroshi Uozaki and Masafumi Kawamura
    Citation: Diagnostic Pathology 2020 15:134
    Content type: Case Report Published on:

  4. Lung cancer (LC) is a malignant tumor originating in the bronchial mucosa or gland of the lung. Circular RNAs (circRNAs) are proved to be key regulators of tumor progression. However, the regulatory effect of ...

    Authors: Koudong Zhang, Hang Hu, Juan Xu, Limin Qiu, Haitao Chen, Xingzhi Jiang and Yongqian Jiang
    Citation: Diagnostic Pathology 2020 15:133
    Content type: Research Published on:

  5. Spitzoid melanocytic lesions represent a heterogeneous group of proliferations with ambiguous and overlapping terminology. The exact distinction of a Spitz nevus from a Spitzoid melanoma can be very difficult ...

    Authors: Jiri Vachtenheim Jr, Roman Kodet, Ondrej Fischer, Vitezslav Kolek, Zuzana Strizova, Andrej Ozaniak, Jan Simonek, Alan Stolz, Jiri Pozniak, Jan Kolarik, Monika Svorcova, Jiri Vachtenheim and Robert Lischke
    Citation: Diagnostic Pathology 2020 15:132
    Content type: Case Report Published on:

  6. Gastric adenocarcinoma of the fundic gland type (GA-FG) has been added to the 2019 edition of the World Health Organization’s list of digestive system-associated cancers. This lesion differentiates toward the ...

    Authors: Chengfang Li, Xinglong Wu, Shuang Yang, Xiaorong Yang, Jin Yao and Hong Zheng
    Citation: Diagnostic Pathology 2020 15:131
    Content type: Research Published on:

  7. The conventional method for the diagnosis of malaria parasites is the microscopic examination of stained blood films, which is time consuming and requires expertise. We introduce computer-based image segmentat...

    Authors: Syed Saiden Abbas and Tjeerd M. H. Dijkstra
    Citation: Diagnostic Pathology 2020 15:130
    Content type: Research Published on:

  8. Histologic features of idiopathic non-cirrhotic portal hypertension (INCPH) may overlap with those without INCPH. Recently, these features have been recognized as part of the larger spectrum of porto-sinusoida...

    Authors: Michel Kmeid, Chunlai Zuo, Stephen M. Lagana, Won-Tak Choi, Jingmei Lin, Zhaohai Yang, Xiuli Liu, Maria Westerhoff, M. Isabel Fiel, Kajsa Affolter, Eun-Young K. Choi and Hwajeong Lee
    Citation: Diagnostic Pathology 2020 15:129
    Content type: Research Published on:

  9. Colorectal T/natural killer (NK)-cell lymphomas (TNKCL) are very rare. Endoscopic and clinicopathological characteristics of colorectal TNKCL have not been clearly demonstrated. In this study, we demonstrated ...

    Authors: Hideki Ishibashi, Satoshi Nimura, Fumihito Hirai, Naohiko Harada, Hiromi Iwasaki, Sigeto Kawauchi, Yumi Oshiro, Atsuji Matsuyama, Shotaro Nakamura, Yasushi Takamatsu, Hirotoshi Yonemasu, Taturo Shimokama and Morishige Takeshita
    Citation: Diagnostic Pathology 2020 15:128
    Content type: Research Published on:

  10. Histologic distinction between well differentiated hepatocellular carcinoma (HCC) and benign hepatocellular mass lesions is a known challenge. Existing biomarkers are of limited diagnostic value. Our previous ...

    Authors: Yuan Li, Fangfang Liu, Wendi Zhou, Sharon Zhang, Peiguo Chu, Fan Lin and Hanlin L. Wang
    Citation: Diagnostic Pathology 2020 15:127
    Content type: Research Published on:

  11. Esophageal squamous cell carcinoma (ESCC) still remains intractable disease with few therapeutic options. Programmed death-ligand 1 (PD-L1), which is essential for immune evasion, is involved in the pathogenes...

    Authors: Hong Kyu Lee, Mi Jung Kwon, Yong Joon Ra, Hee Sung Lee, Hyoung Soo Kim, Eun Sook Nam, Seong Jin Cho, Hye-Rim Park, Soo Kee Min, Jinwon Seo, Ji-Young Choe, Kyueng-Whan Min and So Young Kang
    Citation: Diagnostic Pathology 2020 15:126
    Content type: Research Published on:

  12. Epstein–Barr virus (EBV) is associated with the pathogenesis of a variety of malignancies, most notably lymphomas. Especially in the background of immunodeficiency, such as primary immunodeficiency disorder (P...

    Authors: Yusuke Kajimoto, Yasuhiro Terasaki, Mika Terasaki, Shinobu Kunugi, Yugo Okabe, Satoshi Wakita, Koiti Inokuchi and Akira Shimizu
    Citation: Diagnostic Pathology 2020 15:125
    Content type: Case Report Published on:

  13. The tumor transformation mechanism of a plasmacytoid urothelial carcinoma remains unexplained. We describe the case of a plasmacytoid urothelial carcinoma of the renal pelvis in which the expression of zinc fi...

    Authors: Atsuko Takada-Owada, Yumi Nozawa, Masato Onozaki, Shuhei Noda, Tsengelmaa Jamiyan, Yuumi Tokura, Yoshimasa Nakazato, Takao Kamai and Kazuyuki Ishida
    Citation: Diagnostic Pathology 2020 15:124
    Content type: Case Report Published on:

  14. The presence of histologically different neoplasms in the same organ is rare in pathologic practice. We report the first case of synchronous clear cell renal cell carcinoma (clear cell RCC) and papillary renal...

    Authors: Hyun Jung Lee, Dong Hoon Shin, Joon Young Park, So Young Kim, Chung Su Hwang, Jung Hee Lee, Jee Yeon Kim, Mee Young Sol and Jong Kil Nam
    Citation: Diagnostic Pathology 2020 15:123
    Content type: Case Report Published on:

  15. Cutaneous T-cell lymphomas (CTCL) are a heterogeneous group of extranodal non-Hodgkin lymphomas for which diagnosis can be challenging given the potential for overlap with inflammatory dermatoses. Current diag...

    Authors: Rebecca Rojansky, Sebastian Fernandez-Pol, Erica Wang, Kerri E. Rieger, Roberto A. Novoa, James L. Zehnder, Christian A. Kunder, Youn H. Kim, Michael S. Khodadoust and Ryanne A. Brown
    Citation: Diagnostic Pathology 2020 15:122
    Content type: Case Report Published on:

  16. Cytokeratin-positive interstitial reticulum cells (CIRCs), which are a subgroup of fibroblastic reticular cells (FRCs), are known to be present in the lymph nodes. There have been only a few cases of tumors de...

    Authors: Sachiko Kaji, Nobuyuki Hiruta, Daisuke Sasai, Makoto Nagashima, Rintaro Ohe and Mitsunori Yamakawa
    Citation: Diagnostic Pathology 2020 15:121
    Content type: Case Report Published on:

  17. Hepatic epithelioid hemangioendothelioma is an extremely rare malignant vascular tumor which is often multifocal and, in many cases, discovered incidentally. Here, we describe the clinicopathological features ...

    Authors: Nasir Ud Din, Shabina Rahim, Tamana Asghari, Jamshid Abdul-Ghafar and Zubair Ahmad
    Citation: Diagnostic Pathology 2020 15:120
    Content type: Research Published on:

  18. Uterine adenosarcoma, a rare uterine tumor subtype, is a biphasic tumor consisting of epithelial and mesenchymal elements. To date, there is no research comparing the histopathological features and immunohisto...

    Authors: Makiko Omi, Akiko Tonooka, Tomohiro Chiba, Yuji Tanaka, Atsushi Fusegi, Yoichi Aoki, Hidetaka Nomura, Hiroyuki Kanao and Yutaka Takazawa
    Citation: Diagnostic Pathology 2020 15:119
    Content type: Research Published on:

  19. Carcinosarcoma is a rare neoplasm with a poor prognosis that is most often discovered at an advanced stage; a gastric carcinosarcoma is even rarer than carcinosarcomas originating in other organs, such as the ...

    Authors: Akihiro Shioya, Nozomu Kurose, Kenichi Mizutani, Motona Kumagai, Ken Kawaura, Naohiko Nakamura, Takeo Kosaka, Nozomu Motono, Hidetaka Uramoto and Sohsuke Yamada
    Citation: Diagnostic Pathology 2020 15:118
    Content type: Case Report Published on:

  20. Primary cardiac lymphomas are extremely rare entities (< 2% of cardiac tumours) and the most frequent histologic type is diffuse large B-cell lymphoma (DLBCL). Fibrin-associated DLBCL (FA-DLBCL) is a very unus...

    Authors: Esther Moreno Moreno, Ana Ferrer-Gómez, Héctor Pian Arias, Irene García García and Mónica García-Cosío
    Citation: Diagnostic Pathology 2020 15:117
    Content type: Case Report Published on:

  21. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Danielle J. Fassler, Shahira Abousamra, Rajarsi Gupta, Chao Chen, Maozheng Zhao, David Paredes, Syeda Areeha Batool, Beatrice S. Knudsen, Luisa Escobar-Hoyos, Kenneth R. Shroyer, Dimitris Samaras, Tahsin Kurc and Joel Saltz
    Citation: Diagnostic Pathology 2020 15:116
    Content type: Publisher Correction Published on:

    The original article was published in Diagnostic Pathology 2020 15:100

  22. Lymphoepithelioma-like carcinoma is a rare distinctive variant of liver cancer with unique epidemiological and pathological characteristics, characterized by dense lymphocyte infiltration. It can be divided in...

    Authors: Kai Zhang, Changcheng Tao, Zonggui Tao, Fan Wu, Songlin An, Jianxiong Wu and Weiqi Rong
    Citation: Diagnostic Pathology 2020 15:115
    Content type: Case Report Published on:

  23. While ETV6- NTRK3 fusion is common in infantile fibrosarcoma, NTRK1/3 fusion in pediatric tumors is scarce and, consequently, not well known. Herein, we evaluated for the presence of NTRK1/3 fusion in pediatric m...

    Authors: Jeongwan Kang, Jin Woo Park, Jae-Kyung Won, Jeong Mo Bae, Jaemoon Koh, Jeemin Yim, Hongseok Yun, Seung-Ki Kim, Jung Yoon Choi, Hyoung Jin Kang, Woo Sun Kim, Joo Heon Shin and Sung-Hye Park
    Citation: Diagnostic Pathology 2020 15:114
    Content type: Research Published on:

  24. Fine needle aspiration cytology (FNAC) with rapid on-site evaluation has a great potential for the diagnosis of fungal lesions and other opportunistic infections. Fungal infections have been in increasing tren...

    Authors: Santosh Tummidi, Bitan Naik, Arundhathi Shankaralingappa, Pavithra Balakrishna, Arati Ankushrao Bhadada and Navya Kosaraju
    Citation: Diagnostic Pathology 2020 15:113
    Content type: Case Report Published on:

  25. Peripheral blood smears are performed to evaluate a variety of hematologic and non-hematologic disorders. At the authors’ institutions, clinician requests for pathologist-performed blood smear reviews have inc...

    Authors: Amy K. Beckman, Valerie L. Ng, David L. Jaye, Manila Gaddh, Sarah A. Williams, Sophia L. Yohe, Lin Zhang and Michael A. Linden
    Citation: Diagnostic Pathology 2020 15:112
    Content type: Research Published on:

  26. Crawling-type adenocarcinoma (CRA) is an important gastric cancer (GC) subtype that exhibits a specific histological pattern and has characteristic clinicopathological findings. Despite its characteristic hist...

    Authors: Yasuko Fujita, Noriyuki Uesugi, Ryo Sugimoto, Makoto Eizuka, Yosuke Toya, Risaburo Akasaka, Takayuki Matsumoto and Tamotsu Sugai
    Citation: Diagnostic Pathology 2020 15:111
    Content type: Research Published on:

  27. Uterine tumors resembling ovarian sex-cord tumors (UTROSCTs) are rare mesenchymal neoplasms predominantly arising in perimenopausal and postmenopausal women. UTROSCTs with growth regulation by estrogen in brea...

    Authors: Bin Chang, Qianming Bai, Lin Liang, Huijuan Ge and Qianlan Yao
    Citation: Diagnostic Pathology 2020 15:110
    Content type: Case Report Published on:

  28. Kang and colleagues evaluated on a case series of 1848 breast cancer (BC) patients operated for a first primary ER positive HER2 negative BC if Ki67 expression is a significant prognostic factor only when PgR ...

    Authors: Roberta Maltoni, Michela Palleschi, Sara Ravaioli, Maria Maddalena Tumedei, Mattia Altini and Sara Bravaccini
    Citation: Diagnostic Pathology 2020 15:109
    Content type: Commentary Published on:

  29. Chromogranin A (CgA), synaptophysin (Syn) and the Ki-67 index play significant roles in diagnosis or the evaluation of the proliferative activity of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs). ...

    Authors: Huiying Shi, Chen Jiang, Qin Zhang, Cuihua Qi, Hailing Yao and Rong Lin
    Citation: Diagnostic Pathology 2020 15:108
    Content type: Research Published on:

  31. Intestinal-type adenocarcinoma is widely detected in the gastrointestinal tract, head and neck, lower respiratory and urinary systems. Determining the nature (monoclonal or multicentric) of the intestinal aden...

    Authors: Mikiko Matsuo, Yuichiro Hatano, Yuko Imaizumi, Takahiro Kuroda, Toshinori Arai, Hiroyuki Tomita, Nobuhisa Matsuhashi, Kazuhiro Yoshida and Akira Hara
    Citation: Diagnostic Pathology 2020 15:106
    Content type: Case Report Published on:

  32. Pulmonary epithelial–myoepithelial carcinoma is a rare subtype of lung cancer. Because of its rarity, the molecular information on this carcinoma is insufficient.

    Authors: Naoki Yanagawa, Ayaka Sato, Masao Nishiya, Masamichi Suzuki, Ryo Sugimoto, Mitsumasa Osakabe, Noriyuki Uesugi, Hajime Saito and Tamotsu Sugai
    Citation: Diagnostic Pathology 2020 15:105
    Content type: Case Report Published on:

  33. Squamous cell carcinomas and adenocarcinomas are the most common types of cervical cancer. Compared to squamous cell carcinomas, adenocarcinomas are more common in younger women and have a poorer prognosis. Ye...

    Authors: Hailing Li, Xiaotong Jing, Jie Yu, Jiannan Liu, Tingguo Zhang, Shiming Chen and Xiaofang Zhang
    Citation: Diagnostic Pathology 2020 15:104
    Content type: Research Published on:

  34. The world is currently witnessing a major devastating pandemic of Coronavirus disease-2019 (COVID-19). This disease is caused by a novel coronavirus named Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-...

    Authors: Sambit K. Mohanty, Abhishek Satapathy, Machita M. Naidu, Sanjay Mukhopadhyay, Shivani Sharma, Lisa M. Barton, Edana Stroberg, Eric J. Duval, Dinesh Pradhan, Alexandar Tzankov and Anil V. Parwani
    Citation: Diagnostic Pathology 2020 15:103
    Content type: Review Published on:

  35. Ductal carcinoma of the prostate is a histological subtype with a higher mortality than acinar adenocarcinoma. The number of cases is small and there are no treatment guidelines. We believe that this is the fi...

    Authors: Kota Umeda, Takeo Kosaka, Kohei Nakamura, Toshikazu Takeda, Shuji Mikami, Hiroshi Nishihara and Mototsugu Oya
    Citation: Diagnostic Pathology 2020 15:102
    Content type: Case Report Published on:

  36. MicroRNAs (miRNAs) serve as novel promising biomarkers for the diagnosis and prognosis of many human diseases. This study investigated the diagnostic value of miR-186-5p for asymptomatic carotid artery stenosi...

    Authors: Weibo Lv, Tao Zhang, Hongwei Zhao, Shuang He, Bingwei Li, Yang Gao and Wenying Pan
    Citation: Diagnostic Pathology 2020 15:101
    Content type: Research Published on:

  37. Multiplex immunohistochemistry (mIHC) permits the labeling of six or more distinct cell types within a single histologic tissue section. The classification of each cell type requires detection of uniquely colo...

    Authors: Danielle J. Fassler, Shahira Abousamra, Rajarsi Gupta, Chao Chen, Maozheng Zhao, David Paredes, Syeda Areeha Batool, Beatrice S. Knudsen, Luisa Escobar-Hoyos, Kenneth R. Shroyer, Dimitris Samaras, Tahsin Kurc and Joel Saltz
    Citation: Diagnostic Pathology 2020 15:100
    Content type: Research Published on:

    The Publisher Correction to this article has been published in Diagnostic Pathology 2020 15:116

  38. Molecular diagnostics can be decisive in the differential diagnosis between a somatic metastasis of type II testicular germ cell tumor (TGCT) or a second primary carcinoma. This is in line with recent recommen...

    Authors: Mariëtte E. G. Kranendonk, Wenzel M. Hackeng, G. Johan A. Offerhaus, Folkert H. M. Morsink, Geertruida N. Jonges, Gerard Groenewegen, Pieter-Jaap Krijtenburg, Heinz-Josef Klümpen, Wendy W. J. de Leng, Leendert H. J. Looijenga and Lodewijk A. A. Brosens
    Citation: Diagnostic Pathology 2020 15:99
    Content type: Case Report Published on:

  39. Fibro-adipose vascular anomaly (FAVA) is a new entity of vascular anomalies with somatic and mosaic gain-of-function mutations of the phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit alpha (PIK3C...

    Authors: Yumiko Hori, Katsutoshi Hirose, Noriko Aramaki-Hattori, Sachi Suzuki, Robert Nakayama, Masanori Inoue, Takahiro Matsui, Masaharu Kohara, Satoru Toyosawa and Eiichi Morii
    Citation: Diagnostic Pathology 2020 15:98
    Content type: Case Report Published on:

  40. Malakoplakia is an uncommon, tumor-like inflammatory disease characterized by impaired histiocytes that are unable to completely digest phagocytized bacteria. The genitourinary tract is the most common site of...

    Authors: Michael Lee, Huaibin Mabel Ko, Anthony Rubino, Hwajeong Lee, Ryan Gill and Stephen M. Lagana
    Citation: Diagnostic Pathology 2020 15:97
    Content type: Research Published on:

  41. Several studies reported the dysregulation of miR-541 in the progression of some human malignancies. Osteosarcoma (OS) is one of the most common primary malignant bone tumors. This study aimed to assess the ex...

    Authors: Chunlei Liu and Xiuling Yi
    Citation: Diagnostic Pathology 2020 15:96
    Content type: Research Published on:

  42. Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive neoplasm seen in children and young adults, usually manifested by involvement of abdominal serosa. Here, we present an unusual case of primary ...

    Authors: Dilek Ertoy Baydar, Ayse Armutlu, Oguz Aydin, Ayhan Dagdemir and Yarkin Kamil Yakupoglu
    Citation: Diagnostic Pathology 2020 15:95
    Content type: Case Report Published on:

  43. Bladder cancer (BC) is a common and deadly disease. Over the past decade, a number of genetic alterations have been reported in BC. Bladder urothelium expresses abundant urea transporter UT-B encoded by Slc14a1 g...

    Authors: Zhongying Guo, Xiaobing Niu, Guangbo Fu, Baoxue Yang, Guangping Chen and Su’an Sun
    Citation: Diagnostic Pathology 2020 15:94
    Content type: Case Report Published on:

  44. Patients with 46, XY disorder of sex development (DSD) are predisposed to the development of gonadal tumors, particularly germ cell tumors and gonadoblastoma. However, to the best of our knowledge, there are n...

    Authors: Jiangying Zhao, Jiao Peng, Sisi He, Jia Yang and Xiaojun Pang
    Citation: Diagnostic Pathology 2020 15:93
    Content type: Case Report Published on:

  46. Mesonephric-like adenocarcinoma (M-LAC) is a rare, recently described tumor occurring in the uterine corpus and ovary, which shares the same morphological and immunohistochemical features with the more common ...

    Authors: Pavel Dundr, Mária Gregová, Kristýna Němejcová, Michaela Bártů, Nikola Hájková, Jan Hojný, Ivana Stružinská and Daniela Fischerová
    Citation: Diagnostic Pathology 2020 15:91
    Content type: Case Report Published on:

  47. Takotsubo cardiomyopathy is characterized by transient dysfunction of the medial to apical segment of the left ventricle. Recurrence within a few months or years has been reported and serious complications, in...

    Authors: Kenichi Mizutani, Akihiro Shioya, Yasuyo Hirose, Ryuhei Saito and Sohsuke Yamada
    Citation: Diagnostic Pathology 2020 15:90
    Content type: Case Report Published on:

  48. Anaplastic thyroid carcinoma (ATC) is a rare malignant tumor. In addition to the main ATC type with classical histopathological features, the other morphological types of ATC include paucicellular variant, ang...

    Authors: Jixuan Liu, Ni Cui, Wenjia Ding, Xinjie Dong, Xiaoshuai Chen, Jun Jiang and Yafang Liu
    Citation: Diagnostic Pathology 2020 15:89
    Content type: Case Report Published on:

  49. Malacoplakia is a rare chronic inflammatory disease. The name derives from the Greek “μαλακός” meaning “soft” and “πλάξ” meaning “plaque”, describing its usual macroscopic presentation as a friable yellow soft pl...

    Authors: Antonio d’Amati, Emilio Bellitti and Leonardo Resta
    Citation: Diagnostic Pathology 2020 15:88
    Content type: Case Report Published on:

  50. Identification of bladder layers is a necessary prerequisite to bladder cancer diagnosis and prognosis. We present a method of multi-class image segmentation, which recognizes urothelium, lamina propria, muscu...

    Authors: Muhammad Khalid Khan Niazi, Enes Yazgan, Thomas E. Tavolara, Wencheng Li, Cheryl T. Lee, Anil Parwani and Metin N. Gurcan
    Citation: Diagnostic Pathology 2020 15:87
    Content type: Research Published on:
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Diagnostic Pathology

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