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COVID-19 and impact on peer review

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  2. To distinguish between malignant and benign lesions of the thyroid gland histological demonstration is often required since the fine-needle aspiration biopsy method applied pre-operatively has some limitations...

    Authors: Leandro Luongo de Matos, Adriana Braz Del Giglio, Carolina Ogawa Matsubayashi, Michelle de Lima Farah, Auro Del Giglio and Maria Aparecida da Silva Pinhal
    Citation: Diagnostic Pathology 2012 7:97
    Content type: Review Published on:

  3. Hemophilia A is an X linked recessive hemorrhagic disorder caused by mutations in the F8 gene that lead to qualitative and/or quantitative deficiencies of coagulation factor VIII (FVIII). Molecular diagnosis of h...

    Authors: Hejer Elmahmoudi, Houssein Khodjet-el-khil, Edvard Wigren, Asma Jlizi, Kaouther Zahra, Dorothé Pellechia, Christine Vinciguerra, Balkis Meddeb, Amel Ben Ammar Elggaaied and Emna Gouider
    Citation: Diagnostic Pathology 2012 7:93
    Content type: Research Published on:

  4. Inherited factor VII (FVII) deficiency is a rare disorder characterized by a bleeding phenotype varying from mild to severe. To date, more than 200 mutations have been described along the F7 gene encoding for FVI...

    Authors: Hejer Elmahmoudi, Fatma Ben-lakhal, Wijden Elborji, Asma Jlizi, Kaouther Zahra, Rim Sassi, Moez Zorgan, Balkis Meddeb, Amel Elgaaied Ben Ammar and Emna Gouider
    Citation: Diagnostic Pathology 2012 7:92
    Content type: Research Published on:

  5. The differences between invasive lobular and ductal carcinomas affect the diagnostic and therapeutic management for patients with breast cancer. In most cases, this can be accomplished because of distinct hist...

    Authors: Hacer Haltas, Reyhan Bayrak, Sibel Yenidunya, Dilek Kosehan, Meral Sen and Kayihan Akin
    Citation: Diagnostic Pathology 2012 7:91
    Content type: Case Report Published on:

  6. Translationally Controlled Tumour protein is a multifunctional calcium binding protein which has an important role in apoptosis, calcium levels balance and immunological response. The aim of this study was to ...

    Authors: Cinzia Batisti, Maria R Ambrosio, Bruno J Rocca, Gian M Tosi, Jean C Sanchez, Felice Arcuri, Marcella Cintorino and Sergio A Tripodi
    Citation: Diagnostic Pathology 2012 7:90
    Content type: Research Published on:

  7. Squamous metaplasia presenting in noninvasive mucinous cystic neoplasm (MCN) of the pancreas is extremely rare. We described a case of 39-year-old Chinese female with a 5-year history of a slow growing mass in...

    Authors: Peifeng Li, Yingmei Wang, Qingqing Zhang, Yixiong Liu, Yang Lv and Zhe Wang
    Citation: Diagnostic Pathology 2012 7:89
    Content type: Case Report Published on:

  8. Coronary artery disease (CAD) is a multifactorial disease where genetic and environmental factors interact in complex ways to cause the disease. Heat shock protein genes are involved in the progress of CAD. Th...

    Authors: Mohamed Yahia Hrira, Latifa Chkioua, Afef Slimani, Henda Chahed, Habib Mosbah, Hamda Ben Khaldoun, Salima Ferchichi, Faouzi Addad and Abdelhedi Miled
    Citation: Diagnostic Pathology 2012 7:88
    Content type: Research Published on:

  9. Chronic obstructive pulmonary disease (COPD) is a disorder associated to cigarette smoke and lung cancer (LC). Since epigenetic changes in oncogenes and tumor suppressor genes (TSGs) are clearly important in t...

    Authors: Leda Guzmán, María Soledad Depix, Ana María Salinas, Rosa Roldán, Francisco Aguayo, Alejandra Silva and Raul Vinet
    Citation: Diagnostic Pathology 2012 7:87
    Content type: Research Published on:

  10. The immunohistochemical demonstration of Enhancer of zeste homologue 2 (EZH2) proved to be a useful marker in several tumor types. It has been described to distinguish reliably hepatocellular carcinomas from l...

    Authors: Szofia Hajósi-Kalcakosz, Katalin Dezső, Edina Bugyik, Csaba Bödör, Sándor Paku, Zoltán Pávai, Judit Halász, Krisztina Schlachter, Zsuzsa Schaff and Péter Nagy
    Citation: Diagnostic Pathology 2012 7:86
    Content type: Research Published on:

  11. A 54 year old lady presented for routine excision of a scalp lesion thought clinically to represent a sebaceous cyst of the right occiput. 4 years earlier she underwent total abdominal hysterectomy and right s...

    Authors: Shane Corcoran, Aisling M Hogan, Tamas Nemeth, Fadel Bennani, Francis J Sullivan, Waqar Khan and Kevin Barry
    Citation: Diagnostic Pathology 2012 7:85
    Content type: Case Report Published on:

  13. Inflammatory myofibroblastic tumor is a rare benign lesion whose tumor origin is now proven. It represents 0.7% of all lung tumors. We report the case of a three-year-old child who suffered from a chronic coug...

    Authors: Nawal Hammas, Laila Chbani, Mohammed Rami, Meryem Boubbou, Sara Benmiloud, Youssef Bouabdellah, Siham Tizniti, Mustapha Hida and Afaf Amarti
    Citation: Diagnostic Pathology 2012 7:83
    Content type: Case Report Published on:

  14. Malignant melanoma is the most lethal form of skin cancer with a variable clinical course even in patients with thin melanomas and localized disease. Despite increasing insights into melanoma biology, no progn...

    Authors: Björn Nodin, Marie Fridberg, Liv Jonsson, Julia Bergman, Mathias Uhlén and Karin Jirström
    Citation: Diagnostic Pathology 2012 7:82
    Content type: Research Published on:

  15. Immunohistochemistry using antibody cocktails against basal cell specific and cancer-associated markers is important in the diagnosis of prostate carcinoma in needle biopsies. We compared the usefulness for de...

    Authors: Parag Deepak Dabir, Peter Ottosen, Søren Høyer and Stephen Hamilton-Dutoit
    Citation: Diagnostic Pathology 2012 7:81
    Content type: Research Published on:

  16. Fascin and CD44v6 may have significant roles as biomarkers in tumour progression and metastasis. In endometrioid carcinomas, the fascin expression profile is less defined, and the significance of CD44v6 is unc...

    Authors: Banu Dogan Gun, Burak Bahadir, Sibel Bektas, Figen Barut, Gamze Yurdakan, Nilufer Onak Kandemir and Sukru Oguz Ozdamar
    Citation: Diagnostic Pathology 2012 7:80
    Content type: Research Published on:

  17. Peripheral T-cell lymphomas not otherwise specified are generally considered aggressive non-Hodgkin lymphomas, because of poor natural outcome and response to therapy. They show a complex karyotype without any...

    Authors: Gabriella Aquino, Renato Franco, Fioravante Ronconi, Annamaria Anniciello, Luigi Russo, Annarosaria De Chiara and Luigi Panico
    Citation: Diagnostic Pathology 2012 7:79
    Content type: Case Report Published on:

  18. Bisphosphonates are recommended in the treatment of osteoporosis and some cancers, in which case they prevent the appearance of bone metastasis. The patients taking bisphosphonates are at increased risk of dev...

    Authors: Eugen B Petcu, Saso Ivanovski, Robert G Wright, Mark Slevin, Rodica I Miroiu and Klara Brinzaniuc
    Citation: Diagnostic Pathology 2012 7:78
    Content type: Letter to the Editor Published on:

  19. Paragangliomas are rare neoplasms arising from undifferentiated cells of the primitive neural crest. We report a case of a 57-year-old patient with renal pigmented paraganglioma that was an incidental finding....

    Authors: Ling Zhao, Jie Luo, Honglei Zhang and Jiping Da
    Citation: Diagnostic Pathology 2012 7:77
    Content type: Case Report Published on:

  20. Gastrointestinal (GI) lymphomas are very common types of extranodal lymphomas, and we hypothesize there are regional differences in subtype, distribution in the GI tract, and epidemiological features among the...

    Authors: Joshua Warrick, Jingqin Luo, Diane Robirds, Julie Branson, John L Frater, Friederike Kreisel, Anjum Hassan and TuDung T Nguyen
    Citation: Diagnostic Pathology 2012 7:76
    Content type: Research Published on:

  21. Acute promyelocytic leukemia is a cytogenetically well defined entity. Nevertheless, some features observed at diagnosis are related to a worse outcome of the patients.

    Authors: Mariana R. B. De Mello, Dulcineia M Albuquerque, Fernanda Gonçalves Pereira-Cunha, Krizzia B Albanez, Katia B. B. Pagnano, Fernando F Costa, Konradin Metze and Irene Lorand-Metze
    Citation: Diagnostic Pathology 2012 7:75
    Content type: Research Published on:

  22. Primary malignant melanoma of the duodenum is an unusual oncologic entity. Patients usually present the similar clinical symptoms like other common tumors in this site. And there are no specific radiological f...

    Authors: Hongxia Li, Qinhe Fan, Zhen Wang, Hai Xu, Xiao Li, Weiming Zhang and Zhihong Zhang
    Citation: Diagnostic Pathology 2012 7:74
    Content type: Case Report Published on:

  23. After skin cancer, breast cancer is the most common malignancy in women. Tumors of unknown origin account for 5-15% of malignant neoplasms, with 1.5% being breast cancer. An immunohistochemical panel with conv...

    Authors: Maria de las Mercedes Noriega, Fernando Paesani, Florencia Perazzo, Néstor Lago, Hugo Krupitzki, Silvana Nieto, Alejandro Garcia, Alejandra Avagnina, Boris Elsner and Valeria Cecilia Denninghoff
    Citation: Diagnostic Pathology 2012 7:73
    Content type: Research Published on:

  25. It is not clear if sentinel lymph node (SLN) mapping can improve outcomes in patients with colorectal cancers. The purpose of this study was to determine the prognostic values of ex vivo sentinel lymph node (S...

    Authors: Fu-Long Wang, Fang Shen, De-Sen Wan, Zhen-Hai Lu, Li-Ren Li, Gong Chen, Xiao-Jun Wu, Pei-Rong Ding, Ling-Heng Kong and Zhi-Zhong Pan
    Citation: Diagnostic Pathology 2012 7:71
    Content type: Research Published on:

  27. Immunohistochemical (IHC) assays performed on formalin-fixed paraffin-embedded (FFPE) tissue sections traditionally have been semi-quantified by pathologist visual scoring of staining. IHC is useful for valida...

    Authors: Anthony E Rizzardi, Arthur T Johnson, Rachel Isaksson Vogel, Stefan E Pambuccian, Jonathan Henriksen, Amy PN Skubitz, Gregory J Metzger and Stephen C Schmechel
    Citation: Diagnostic Pathology 2012 7:42
    Content type: Research Published on:

  28. The aberrant expression of regenerating islet-derived family member, 4 (Reg IV) has been found in various human cancers. However, the roles of Reg IV gene and its encoding product in human glioma have not been...

    Authors: Qi Wang, Jianping Deng, Jun Yuan, Liang Wang, Zhenwei Zhao, Shiming He, Yongsheng Zhang and Yanyang Tu
    Citation: Diagnostic Pathology 2012 7:69
    Content type: Research Published on:

  29. The prediction of pathological outcomes prior to surgery remains a challenging problem for the appropriate surgical indication of prostate cancer. This study was performed to identify preoperative values predi...

    Authors: Fumio Ishizaki, Noboru Hara, Hiroshi Koike, Makoto Kawaguchi, Akira Tadokoro, Itsuhiro Takizawa, Tsutomu Nishiyama, Kota Takahashi and Rudolf Hohenfellner
    Citation: Diagnostic Pathology 2012 7:68
    Content type: Research Published on:

  31. Genomic tumor information, such as identification of amplified oncogenes, can be used to plan treatment. The two sources of a brain tumor that are commonly available include formalin-fixed, paraffin-embedded (...

    Authors: Long N Truong, Shashikant Patil, Sherry S Martin, Jay F LeBlanc, Anil Nanda, Mary L Nordberg and Marie E Beckner
    Citation: Diagnostic Pathology 2012 7:66
    Content type: Methodology Published on:

  32. Delayed neutrophil apoptosis may be an important factor in the persistent inflammation associated with chronic obstructive pulmonary disease (COPD). Bcl-2 family proteins are important regulators of neutrophil...

    Authors: Jisong Zhang, Jian He, Jingwen Xia, Zhen Chen and Xiaodong Chen
    Citation: Diagnostic Pathology 2012 7:65
    Content type: Research Published on:

  33. Hodgkin lymphoma (HL) typically presents as nodal lesion and may involve extranodal sites during the progression of the disease. Primary osseous HL without any lymph node association is extremely rare and only...

    Authors: Yang Li, Xiao-bing Wang, Xiao-ying Tian, Bin Li and Zhi Li
    Citation: Diagnostic Pathology 2012 7:64
    Content type: Case Report Published on:

  34. Association between DNA alterations and clinical parameters as recurrence, survival or prognosis has been found in a variety of tumors. A clear association between Medullary Thyroid Carcinoma (MTC) and RET onc...

    Authors: Beatriz González-Yebra, Raúl Peralta, Ana Lilia González, Marco Antonio Ayala-Garcia, María E Medrano Ortiz de Zarate and Mauricio Salcedo
    Citation: Diagnostic Pathology 2012 7:63
    Content type: Case Report Published on:

  35. Cecal endometriosis and ileocolic intussusception due to a cecal endometriosis is extremely rare. We report a case of a woman who presented an ileocecal intussusception due to a cecal endometriosis. The patien...

    Authors: Rivkine Emmanuel, Marciano Léa, Polliand Claude, Valenti Antonio, Ziol Marianne, Poncelet Christophe and Barrat Christophe
    Citation: Diagnostic Pathology 2012 7:62
    Content type: Case Report Published on:

    The Correction to this article has been published in Diagnostic Pathology 2018 13:58

  36. A history of a recent rapid increase in long-standing swelling mass was presented in the right parotid gland of an 85-year-old male. The inadequate cytologic specimens contained few small clusters of three-dim...

    Authors: Sohsuke Yamada, Atsunori Nabeshima, Takahisa Tabata, Xin Guo, Takashi Tasaki, Ke-Yong Wang, Shohei Shimajiri and Yasuyuki Sasaguri
    Citation: Diagnostic Pathology 2012 7:61
    Content type: Case Report Published on:

  37. The eligibility of breast cancer patients for human epidermal growth factor receptor 2 (HER2)-directed therapies is determined by the HER2 gene amplification and/or HER2 protein overexpression status of the breas...

    Authors: Hiroaki Nitta, Brian D Kelly, Mary Padilla, Nikolaus Wick, Patrick Brunhoeber, Isaac Bai, Shalini Singh, Jim Ranger-Moore, Chris Bieniarz, Hitoshi Tsuda and Thomas M Grogan
    Citation: Diagnostic Pathology 2012 7:60
    Content type: Methodology Published on:

  38. Serrated polyps belong to a heterogeneous group of lesions that are generally characterized morphologically. This type of lesion is thought to be the precursor of sporadic carcinomas with microsatellite instab...

    Authors: Yukari Fujimori, Takahiro Fujimori, Johji Imura, Tamotsu Sugai, Takashi Yao, Ryo Wada, Yoichi Ajioka and Yasuo Ohkura
    Citation: Diagnostic Pathology 2012 7:59
    Content type: Research Published on:

  39. Renal cell carcinoma (RCC) is characterized by its resistance to radiotherapy and/or chemotherapy. On the other hand, it is an immunogenic tumor - it is able to stimulate antitumor responses. A prognostic sign...

    Authors: Leos Kren, Ivo Valkovsky, Jan Dolezel, Ivo Capak, Dalibor Pacik, Alexandr Poprach, Radek Lakomy, Martina Redova, Pavel Fabian, Zdenka Krenova and Ondrej Slaby
    Citation: Diagnostic Pathology 2012 7:58
    Content type: Research Published on:

  40. c-MET is an oncogene protein that plays important role in gastric carcinogenesis and has been introduced as a prognostic marker and potential therapeutic target. The aim of this study was to evaluate the frequ...

    Authors: Kambiz Sotoudeh, Forough Hashemi, Zahra Madjd, Alireza Sadeghipour, Saadat Molanaei and Elham Kalantary
    Citation: Diagnostic Pathology 2012 7:57
    Content type: Research Published on:

  42. To evaluate the influence of corneal astigmatism (CA) on retinal nerve fiber layer (RNFL) thickness and optic nerve head(ONH) parameters measured with spectral-domain optical coherence tomography (OCT) in high...

    Authors: Lin Liu, Jun Zou, Hui Huang, Jian-guo Yang and Shao-rong Chen
    Citation: Diagnostic Pathology 2012 7:55
    Content type: Research Published on:

  44. We previously investigated the current status of breast cytology cancer screening at seven institutes in our area of southern Fukuoka Prefecture, and found some differences in diagnostic accuracy among the ins...

    Authors: Rin Yamaguchi, Shin-ichi Tsuchiya, Takashi Koshikawa, Toshiro Yokoyama, Kuniko Mibuchi, Yasuhide Nonaka, Sonoe Ito, Hidejiro Higuchi, Mariko Nagao, Koichi Higaki, Jiro Watanabe, Masayoshi Kage and Hirohisa Yano
    Citation: Diagnostic Pathology 2012 7:53
    Content type: Research Published on:

  46. We report a 32-year-old Outer Mongolian man, with plasmablastic lymphoma (PBL) primarily occured in the central nervous system and diagnosed by surgical resection. This patient appeared headache and Magnetic r...

    Authors: Li Ying Zhang, Hui Yun Lin, Lan Xiang Gao, Lin Li, Yu Wang Tian, Zhi Qin Liu, Xiao Hua Shi and Zhi Yong Liang
    Citation: Diagnostic Pathology 2012 7:51
    Content type: Case Report Published on:

  47. Angioimmunoblastic T-cell lymphoma is one of the most common subtypes of peripheral T-cell lymphoma (15-20% of all cases), accounting for approximately 1-2% of all non-Hodgkin lymphomas. It often presents auto...

    Authors: Maria Raffaella Ambrosio, Bruno Jim Rocca, Alessandro Ginori, Monica Onorati, Alberto Fabbri, Mario Carmellini, Stefano Lazzi and Sergio Tripodi
    Citation: Diagnostic Pathology 2012 7:50
    Content type: Case Report Published on:

  48. Hemangioblastoma is a benign and morphologically distinctive tumor that can occur sporadically or in association with von Hippel-Lindau disease in approximately 25% of the cases, and which involves the central...

    Authors: Yang Liu, Xue-shan Qiu and En-Hua Wang
    Citation: Diagnostic Pathology 2012 7:49
    Content type: Case Report Published on:

  50. Genital rhabdomyoma is very rare tumor that usually occurs in the vulvar of young women. Epididymis rhabdomyoma in a young man is extremely uncommon and has rarely been reported. Here, we report a case of epid...

    Authors: Yang Han, Xue-shan Qiu, Qing-chang Li, Yu-chen Han, Xu-yong Lin, Qing-fu Zhang, Jian Wang, En-hua Wang and Ze-liang Li
    Citation: Diagnostic Pathology 2012 7:47
    Content type: Case Report Published on:
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Diagnostic Pathology

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