From: Association of the interleukin-22 genetic polymorphisms with ulcerative colitis
 | Cases (n = 180) | TT | TA | AA | ||||||
---|---|---|---|---|---|---|---|---|---|---|
n (%) | OR (95% CI) | P | n (%) | OR (95% CI) | P | n (%) | OR (95% CI) | P | ||
Clinical type | 180 | 88(48.9) | 1(Reference) | Â | 63(35.0) | 1(Reference) | Â | 29(16.1) | 1(Reference) | Â |
One episode | 16 | 7(43.7) | 0.89(0.35,2.55) | 0.81 | 6(37.6) | 1.07(0.40,2.86) | 0.89 | 3(18.7) | 1.16(0.32,4.25) | 0.82 |
Relapsing | 70 | 33(47.1) | 0.96(0.59,1.57) | 0.88 | 26(37.2) | 1.06(0.62,1.81) | 0.83 | 11(15.7) | 0.98(0.46,2.06) | 0.95 |
Continuous | 94 | 48(51.1) | 1.04(0.68,1.61) | 0.84 | 31(33.0) | 0.94(0.57,1.55) | 0.82 | 15(15.9) | 0.99(0.51,1.94) | 0.98 |
Location | 180 | 88(48.9) | 1(Reference) | Â | 63(35.0) | 1(Reference) | Â | 29(16.1) | 1(Reference) | Â |
Proctitis (E1) | 73 | 37(50.7) | 1.04(0.65,1.66) | 0.88 | 25(34.2) | 0.98(0.57,1.67) | 0.94 | 11(15.1) | 0.94(0.44,1.97) | 0.86 |
Left side (E2) | 64 | 33(51.6) | 1.06(0.65,1.72) | 0.83 | 21(32.8) | 0.94(0.53,1.66) | 0.82 | 10(15.6) | 0.97(0.45,2.10) | 0.94 |
Extensive (E3) | 43 | 18(41.9) | 0.86(0.47,1.57) | 0.62 | 17(39.5) | 1.13(0.60,2.12) | 0.70 | 8(18.6) | 1.16(0.49,2.70) | 0.74 |
Disease severity | 180 | 88(48.9) | 1(Reference) | Â | 63(35.0) | 1(Reference) | Â | 29(16.1) | 1(Reference) | Â |
Mild | 76 | 35(46.1) | 0.94(0.59,1.51) | 0.81 | 28(36.8) | 1.05(0.63,1.77) | 0.85 | 13(17.1) | 1.06(0.52,2.15) | 0.87 |
Moderate | 95 | 48(50.5) | 1.03(0.67,1.59) | 0.88 | 32(33.7) | 0.96(0.59,1.58) | 0.88 | 15(15.8) | 0.98(0.50,1.92) | 0.95 |
Severe | 9 | 5(55.6) | 1.14(0.37,3.49) | 0.82 | 3(33.3) | 0.95(0.25,3.63) | 0.94 | 1(11.1) | 0.69(0.08,5.65) | 0.73 |