Table 1 Examples of combinative scoring system for histomorphometry
Score | Bondarenko et al. for OCN*[[68]] | Bondarenko et al. for OPN[[68]] | Torre et al. for VEGF-A, VEGF-C and FGF-2[[102]] |
|---|---|---|---|
0 | - | - | Negative |
1 | <25% | Expression in cells only | <5% of the cells with positive staining |
2 | 25-50% | Expression in cells and osteoid | Between 5 and 50% of the cells with positive staining |
3 | 50-75% | Focal expression in mature bone | >50% of the cells with weak staining |
4 | >75% | Diffuse expression in mature bone | > 50% of the cells with strong staining |