Fig. 4

Identification of hub genes. A Scatter diagram of genes in brown module. Each red circle represents a gene. B PPI network of all genes in the hub module. The outermost circle is the center node. C Overlapping genes between the PPI network and scatter diagram (module connectivity > 0.8 and clinical trait relationship > 0.5) were selected as hub genes. D PPI network of the 9 hub genes. PPI, protein-protein interaction