Uterine choriocarcinoma arising from serous carcinoma in a postmenopausal woman: an analysis of next-generation sequencing and PD-L1 immunochemistry

Table 1 Epithelial malignancies with choriocarcinomatous differentiation in female genital organs

Case	age	organ	Final diagnosis	Stage surgery	FIGO stage	Follow up	reference
Case 1	50	Ovary	EAC + CC, SCC + CCC	TH-RSO, P LN;	IV	DOD 10 m	3
Case 2	48	ovary	CCC + CC	TH-BSO, OM, DO;	IV	DOD 11 m	4
Case 3	59	uterus	EAC + CC	TH-BSO, PLN	IIIC2	NED 2 m	5
Case 4	54	uterus	EC, G1 + CC	TH-BSO, SCR,	III	DOD 15 m	6
Case 5	61	uterus	ESC + CC	TH-BSO, PLN,	IV	DOD 2 m	7
Case 6	42	uterus	EAC + CC	TH-BSO, OM, AP, PLN	IB	NED 6 m	8
Case 7	34	uterus	Carcinosarcoma + CC	TH-BSO, OM, PLN	IV	DOD7m	9
Case 8	72	uterus	DEC + CC	TH-BSO, PLN, OM	IIIA	DOD7m	10
Case 9	77	uterus	EC, G1 + CC	TH-BSO, PLN, OM	IIIC2	DOD11m
Case 10	62	uterus	DEC + CC	TH-BSO, PLN	IIIC1	DOD16m
Case 11	68	uterus	ESC + CC	TH-BSO, MB, PLN	IIIA	DOD13m	Our case

EAC Endometrial adenocarcinoma, CCC Clear cell carcinoma, SCC Small cell carcinoma, ESC Endometrail serous carcinoma, DEC Dedifferentiated enodmetrial carcinoma, CC Choriocarcinoma, EC Endometrioid carcinoma, G1 Grade 1, TH-BSO Total hysterectomy with bilateral salpingo-oophorectomy, MB Multiple biopsies, TH-RSO Total hysterectomy with right salpingo-oophorectomy, PLN Pelvic lymphadenectomy, AP Appendectomy, OM Omentectomy, SCR Sigmoid colon resection, DO Debulking operation, DOD Dead of disease, NED No evidence of the disease

ISSN: 1746-1596