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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Ovarian cancer is a spectrum of several histologically distinct tumor types that differ in etiology, response to therapy, and prognosis. In resource-limited settings, the diagnosis of ovarian cancer can be cha...

    Authors: Peter F. Rambau, Martin Köbel, Derek Tilley, Alex Mremi, Robert Lukande and William Muller
    Citation: Diagnostic Pathology 2020 15:86
    Content type: Research Published on:

  3. Immunohistochemistry (IHQ) is commonly used for the detection of mismatch repair proteins deficiency (MMRD). One very infrequent abnormal pattern of MMR protein expression is the loss of PMS2 and MSH6, with in...

    Authors: Esther Moreno, Juan M. Rosa-Rosa, Tamara Caniego-Casas, Ignacio Ruz-Caracuel, Cristian Perna, Carmen Guillén and José Palacios
    Citation: Diagnostic Pathology 2020 15:84
    Content type: Case Report Published on:

  4. E-cigarette and vaping use-associated acute lung injury (EVALI) has been recently recognized as a complication in individuals who use vaping devices. Another consideration is that EVALI may have an adverse inf...

    Authors: Bindu H. Akkanti, Rahat Hussain, Manish K. Patel, Jayeshkumar A. Patel, Kha Dinh, Bihong Zhao, Shaimaa Elzamly, Kevin Pelicon, Klemen Petek, Ismael A. Salas de Armas, Mehmet Akay, Biswajit Kar, Igor D. Gregoric and L. Maximilian Buja
    Citation: Diagnostic Pathology 2020 15:83
    Content type: Case Report Published on:

    The Correction to this article has been published in Diagnostic Pathology 2023 18:58

  5. Primary intestinal follicular lymphoma (PI-FL) is a rare and indolent lymphoma and is challenging for diagnosis with endoscopic biopsy specimens. Whole slide imaging (WSI) has been increasingly used for assist...

    Authors: Hsin-Ni Li, Ren Ching Wang, Jun-Peng Chen, Sheng-Tsung Chang and Shih-Sung Chuang
    Citation: Diagnostic Pathology 2020 15:82
    Content type: Research Published on:

  6. Pathologists frequently encounter neuroendocrine tumors (NETs) presenting as multiple liver masses in routine practice. Most often, these are well-differentiated tumors with characteristic histologic features....

    Authors: Elise R. Venable, Sarah E. Kerr, M. Beatriz S. Lopes, Karra A. Jones, Andrew M. Bellizzi, Taofic Mounajjed, Aditya Raghunathan, Oksana Hamidi, Thorvardur R. Halfdanarson, Mabel Ryder and Rondell P. Graham
    Citation: Diagnostic Pathology 2020 15:81
    Content type: Research Published on:

  7. The mitotic count in breast carcinoma is an important prognostic marker. Unfortunately substantial inter- and intra-laboratory variation exists when pathologists manually count mitotic figures. Artificial inte...

    Authors: Liron Pantanowitz, Douglas Hartman, Yan Qi, Eun Yoon Cho, Beomseok Suh, Kyunghyun Paeng, Rajiv Dhir, Pamela Michelow, Scott Hazelhurst, Sang Yong Song and Soo Youn Cho
    Citation: Diagnostic Pathology 2020 15:80
    Content type: Research Published on:

  8. Without early recognition and Kasai procedure, biliary atresia (BA) results in liver cirrhosis and leads to either transplantation or death at a young age. We aimed to characterize the liver histopathological ...

    Authors: Gunadi, Dian Nirmala Sirait, Leila Rakhma Budiarti, Vincentia Meta Widya Paramita, Aditya Rifqi Fauzi, Fiko Ryantono, Dwiki Afandy, Naomi Yoshuantari, Hanggoro Tri Rinonce and Akhmad Makhmudi
    Citation: Diagnostic Pathology 2020 15:79
    Content type: Research Published on:

  9. The outbreak of a novel coronavirus since December 2019, became an emergency of major international concern. As of June 21, 2020, the SARS-CoV-2 pandemic has caused 8,769,844 confirmed infections with 463,745 ...

    Authors: Pan Zhai, Yanbing Ding and Yiming Li
    Citation: Diagnostic Pathology 2020 15:78
    Content type: Case Report Published on:

  10. This study evaluated the predictive power of Atyp.C (a parameter of UF-5000 flow cytometer) for patients with a suspected diagnosis of urothelial carcinoma.

    Authors: Chunyun Ren, Xing Wang, Chunwei Yang, Shengchao Li, Shuangchun Liu and Hongcui Cao
    Citation: Diagnostic Pathology 2020 15:77
    Content type: Research Published on:

  12. We examined the vascularity of mammary Paget disease histologically to confirm the increased blood flow observed previously by clinical imaging. The relationships among blood vessel density (BVD), histopatholo...

    Authors: Yuri Akishima-Fukasawa, Naoko Honma, Hideaki Ogata, Yoshikiyo Akasaka and Tetuo Mikami
    Citation: Diagnostic Pathology 2020 15:75
    Content type: Research Published on:

  13. Early diagnosis of asymptomatic carotid artery stenosis (ACAS) is important to prevent the incidence of cerebrovascular events. This study aimed to investigate the circulating expression of microRNA-92a (miR-9...

    Authors: Gang Chen, Jianwei Gao, Yuguo Sheng, Xinqiang Han, Xingang Ji, Mengpeng Zhao and Jian Wu
    Citation: Diagnostic Pathology 2020 15:74
    Content type: Research Published on:

  14. In lung cancer patients infected with COVID-19, pathological features are not easy to distinguish. This report presents detailed histopathological findings in two non-neoplastic subjects whose out-of-hospital ...

    Authors: Roberto Scendoni, Francesca Marchesani, Nunzia Cannovo, Piergiorgio Fedeli and Mariano Cingolani
    Citation: Diagnostic Pathology 2020 15:73
    Content type: Commentary Published on:

  15. Intravascular large B-cell lymphoma (IVLBCL) is an extremely rare subtype of diffuse large B-cell lymphoma that most commonly involves the central nervous system, skin, and bone marrow. To our knowledge, Epste...

    Authors: Qingjiao Li, Jinghe Li, Keda Yang, Ying Peng, Yao Xiang, Shuyuan Sun, Jian Zeng, Xin Zhang and Junpu Wang
    Citation: Diagnostic Pathology 2020 15:72
    Content type: Case Report Published on:

  16. Primary myoepithelial carcinoma of the lung is a rare subtype in lung cancer. Comprehensive molecular profiling of myoepithelial carcinoma of the lung is absent, neither was clinical evidence of targeted thera...

    Authors: Xiaohong Xie, Xinqing Lin, Ming Liu, Yinyin Qin, Ming Ouyang, Shiyue Li, Yingying Gu, Shuyin Chen, Jianxing Xiang and Chengzhi Zhou
    Citation: Diagnostic Pathology 2020 15:71
    Content type: Case Report Published on:

  18. The prognostic potential of PD-L1 is currently unclear in gastric carcinomas, although the immune checkpoint PD-1/PD-L1 inhibitors have produced promising results in clinical trials.

    Authors: Euno Choi, Mee Soo Chang, Sun-ju Byeon, Heejin Jin, Kyeong Cheon Jung, Haeryoung Kim, Kook Lae Lee, Won Kim, Jin Hyun Park, Ki Hwan Kim, Jin-Soo Kim, In Sil Choi, Dong-Seok Han, Hye Seong Ahn and Seung Chul Heo
    Citation: Diagnostic Pathology 2020 15:69
    Content type: Research Published on:

  19. Yolk sac tumor (YST) is a germ cell neoplasm that arises predominantly in the gonads, but can also derive from somatic neoplasms in extragonadal locations. These latter cases have been documented in several or...

    Authors: Nadia Espejo-Herrera and Enric Condom-Mundó
    Citation: Diagnostic Pathology 2020 15:68
    Content type: Case Report Published on:

  22. The scoring of Ki-67 is highly relevant for the diagnosis, classification, prognosis, and treatment in breast invasive ductal carcinoma (IDC). Traditional scoring method of Ki-67 staining followed by manual co...

    Authors: Min Feng, Yang Deng, Libo Yang, Qiuyang Jing, Zhang Zhang, Lian Xu, Xiaoxia Wei, Yanyan Zhou, Diwei Wu, Fei Xiang, Yizhe Wang, Ji Bao and Hong Bu
    Citation: Diagnostic Pathology 2020 15:65
    Content type: Research Published on:

  23. Bartholin gland carcinomas (BGCs) are rare tumor types, for which no molecular analyses including genomic sequencing have been reported to date. Adenoid cystic carcinomas (ACCs) of the Bartholin’s glands are a...

    Authors: Kohei Nakamura, Eriko Aimono, Shigeki Tanishima, Hidetaka Nomura, Mitsuho Imai, Hideyuki Hayashi and Hiroshi Nishihara
    Citation: Diagnostic Pathology 2020 15:64
    Content type: Case Report Published on:

  24. Recently, FAM83H was reported to have roles in cancer progression in conjunction with oncogenic molecules such as MYC and b-catenin. Moreover, the data from the public database indicates a molecular relationsh...

    Authors: Sung Woo Ahn, Ae-Ri Ahn, Sang Hoon Ha, Usama Khamis Hussein, Jae Do Yang, Kyoung Min Kim, Ho Sung Park, See-Hyoung Park, Hee Chul Yu and Kyu Yun Jang
    Citation: Diagnostic Pathology 2020 15:63
    Content type: Research Published on:

  25. Infection-related glomerulonephritis with IgA deposits (IRGN-IgA) is a rare disease but it is increasingly reported in the literature. Data regarding epidemiology and outcome are lacking, especially in Europe....

    Authors: Elodie Miquelestorena-Standley, Charlotte Jaulerry, Marie-Christine Machet, Nolwenn Rabot, Christelle Barbet, Aurélie Hummel, Alexandre Karras, Cyril Garrouste, Thomas Crepin, Didier Ducloux, Maud Cousin, Catherine Albert, Joseph Rivalan, Emilie Cornec-Le Gall, François Pourreau, Clément Deltombe…
    Citation: Diagnostic Pathology 2020 15:62
    Content type: Research Published on:

  27. Glioma-associated oncogene homolog 1 (Gli1), affects the progression and the stemness characteristics of malignant carcinoma. The aim of the present study was to identify the relation between Glioma-associated...

    Authors: Wenbo Qi, Zhaoting Yang, Ying Feng, Haoyue Li, Nan Che, Lan Liu and Yanhua Xuan
    Citation: Diagnostic Pathology 2020 15:60
    Content type: Research Published on:

  28. A specialized classification for small biopsies was added to the 2015 WHO classification of lung tumors. The purpose of this study is to explore and summarize the experience of applying the newly proposed clas...

    Authors: Yupeng Zeng, Yunxiang Zhu, Ying Ding, Liuyang Xu, Boya Zhai, Xiang Zhang, Qiaoyun Ge, Jiao Li, Qiyuan Song, Xiao Li and Zhihong Zhang
    Citation: Diagnostic Pathology 2020 15:59
    Content type: Research Published on:

  29. Inflammatory myofibroblastic tumors (IMTs) of the thyroid are extremely rare soft-tissue tumors. In the literature, IMTs are sometimes called plasma cell granulomas (PCGs) or inflammatory pseudotumors, which o...

    Authors: Cheng-fang Li, Xing-long Wu, Jin-jing Wang, Kai Wang, Su-yuan Zhang, Jia-jia Huang, Han-zhong Hu and Hong Zheng
    Citation: Diagnostic Pathology 2020 15:58
    Content type: Case Report Published on:

  30. Digital multiplex gene expression profiling is overcoming the limitations of many tissue-processing and RNA extraction techniques for the reproducible and quantitative molecular classification of disease. We a...

    Authors: Jelena Vider, Andrew Croaker, Amanda J. Cox, Emma Raymond, Rebecca Rogers, Stuart Adamson, Michael Doyle, Blake O’Brien, Allan W. Cripps and Nicholas P. West
    Citation: Diagnostic Pathology 2020 15:57
    Content type: Research Published on:

  31. Most sporadic gastrointestinal stromal tumors (GISTs) occur as solitary tumors, while multiple sporadic GISTs are extremely rare and often misdiagnosed as metastatic GISTs, leading to inappropriate treatment. ...

    Authors: Yan-Ying Shen, Xin-Li Ma, Lin-Xi Yang, Wen-Yi Zhao, Lin Tu, Chun Zhuang, Bo Ni, Qiang Liu, Ming Wang and Hui Cao
    Citation: Diagnostic Pathology 2020 15:56
    Content type: Research Published on:

  33. Hepatocellular carcinoma (HCC) is one of the most common global malignancies with increasing morbidity and mortality. The purpose of this study was to investigate the expression levels and prognostic value of ...

    Authors: Wenwen Dou, Min Yang, Yan Su and Ruizhu Xie
    Citation: Diagnostic Pathology 2020 15:54
    Content type: Research Published on:

  34. Chondromesenchymal hamartoma of the chest wall is a rare, benign disease that usually presents at birth or in early infancy. It typically involves one or more ribs, forming a unilateral or bilateral extrapleur...

    Authors: Yue Li, Danyang Zheng, Min Zuo, Yang Li and Huizhong Zhang
    Citation: Diagnostic Pathology 2020 15:53
    Content type: Case Report Published on:

  35. Histologic grade of ductal carcinoma in situ of the breast (DCIS) may become the single biomarker that decides whether patients will be treated. Yet, evidence shows that grading variation in daily practice is ...

    Authors: Carmen van Dooijeweert, Paul J. van Diest, Inge O. Baas, Elsken van der Wall and Ivette A. G. Deckers
    Citation: Diagnostic Pathology 2020 15:52
    Content type: Research Published on:

  36. Acral and cutaneous melanomas are usually difficult to accurately diagnose in the early stage, owing to the similarity in clinical manifestations and morphology with those of dysplastic nevus (DN). In this stu...

    Authors: Yumei Lai, Yan Wu, Ruping Liu, Aiping Lu, Lixin Zhou, Lin Jia, Xinting Diao and Zhongwu Li
    Citation: Diagnostic Pathology 2020 15:51
    Content type: Research Published on:

  37. Immunotherapy has demonstrated encouraging clinical benefits in patients with advanced breast carcinomas and Programmed death ligand 1 (PD-L1) expression has been proposed as an immunotherapy biomarker. Challe...

    Authors: Ping Mei, C. Eric Freitag, Lai Wei, Yunxiang Zhang, Anil V. Parwani and Zaibo Li
    Citation: Diagnostic Pathology 2020 15:50
    Content type: Research Published on:

  38. The objective of this study was to investigate genetic variations and the relationships between these genetic variations and clinicopathological features of high-recurrence risk papillary thyroid carcinoma in ...

    Authors: Min Li, Haitao Jia, Qiuqin Qian, Peng Wen, Chuan Chen, Yaqiong Hua, Kai Wang, Wenyong Zhang and Feng Shi
    Citation: Diagnostic Pathology 2020 15:49
    Content type: Research Published on:

  39. Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a rare disorder of pulmonary vascular abnormality with persistent pulmonary hypertension of the newborn. The symptom usually prese...

    Authors: Akiko Kitano, Masato Nakaguro, Seiichi Tomotaki, Shintaro Hanaoka, Masahiko Kawai, Akiko Saito, Masahiro Hayakawa, Yoshiyuki Takahashi, Hidenori Kawasaki, Takahiro Yamada, Masahiko Ikeda, Tetsuo Onda, Kazutoshi Cho, Hironori Haga, Atsuko Nakazawa and Sachiko Minamiguchi
    Citation: Diagnostic Pathology 2020 15:48
    Content type: Case Report Published on:

  40. Among cancers affecting the oral cavity, adenoid cystic carcinoma (ACC) is a relatively common malignant neoplasm. It has high rates of metastasis and recurrence and is associated with significant morbidity. D...

    Authors: Raíssa Pinheiro de Mendonça, Giordanna Pereira Chemelo, Geovanni Pereira Mitre, Dimitra Castelo Branco, Natacha Malu Miranda da Costa, Fabrício Mesquita Tuji, Maria Sueli da Silva Kataoka, Ricardo Alves Mesquita, Sérgio de Melo Alves Júnior and João de Jesus Viana Pinheiro
    Citation: Diagnostic Pathology 2020 15:47
    Content type: Research Published on:

  41. Temporal lobe epilepsy (TLE) is the most common type of epilepsy, usually starting in childhood. The dysregulation of microRNAs (miRNAs) has been identified in neurological disorders. The current study investi...

    Authors: Na Li, Jingmei Pan, Wei Liu, Yuanyuan Li, Feng Li and Min Liu
    Citation: Diagnostic Pathology 2020 15:46
    Content type: Research Published on:

  42. Human papillomavirus (HPV) testing has been employed by several European countries to augment cytology-based cervical screening programs. A number of research groups have demonstrated potential utility of next...

    Authors: Wai Sing Chan, Tsun Leung Chan, Chun Hang Au, Chin Pang Leung, Man Yan To, Man Kin Ng, Sau Man Leung, May Kwok Mei Chan, Edmond Shiu Kwan Ma and Bone Siu Fai Tang
    Citation: Diagnostic Pathology 2020 15:45
    Content type: Short report Published on:

  43. Blood malignancies are among the leading causes of cancer related deaths in the world. Different environmental and genetic risk factors are involved in progression of blood malignancies. It has been shown that...

    Authors: Majid Ghayour-Mobarhan, Amir Sadra Zangouei, Seyed Mohammad Hosseinirad, Majid Mojarrad and Meysam Moghbeli
    Citation: Diagnostic Pathology 2020 15:44
    Content type: Review Published on:

  44. Liver is one of the most common organs involved by metastatic neoplasms. In addition, a number of primary tumors can arise in the liver. Fine needle biopsy (FNB) is the most commonly used method for diagnosis ...

    Authors: Lin Zhang, Zhenjian Cai, Joe Rodriguez, Songlin Zhang, Jaiyeola Thomas and Hui Zhu
    Citation: Diagnostic Pathology 2020 15:43
    Content type: Research Published on:

  45. The prevalence of EGFR/ALK co-alterations in patients with NSCLC was low. The several previous studies focused on the simultaneous occurrence of EGFR mutations and ALK rearrangements in a unifocal lung cancer....

    Authors: Jun Fan, Junhua Wu, Bo Huang, Yili Zhu, Heshui Shi, Xiaofang Dai and Xiu Nie
    Citation: Diagnostic Pathology 2020 15:42
    Content type: Case Report Published on:

  46. Diversified etiology of lower respiratory tract infection renders diagnosis challenging. The mainstay microbial culture is time-consuming and constrained by variable growth requirements. In this study, we expl...

    Authors: Wai Sing Chan, Chun Hang Au, Sau Man Leung, Dona N. Ho, Elaine Yue Ling Wong, Man Yan To, Man Kin Ng, Tsun Leung Chan, Edmond Shiu Kwan Ma and Bone Siu Fai Tang
    Citation: Diagnostic Pathology 2020 15:41
    Content type: Short report Published on:

  47. Inverted urothelial papilloma (IUP) of the upper urinary tract is an uncommon benign tumour that occasionally presents as a polypoid mass causing urinary obstruction. Histologically, IUP is characterised by a ...

    Authors: R. Santi, I. C. Galli, V. Canzonieri, J. I. Lopez and G. Nesi
    Citation: Diagnostic Pathology 2020 15:40
    Content type: Research Published on:

  48. Progressive familial intrahepatic cholestasis (PFIC) is a rare group of autosomal recessive hereditary hepatic diseases. There are three types of PFIC, classified according to the mutated gene. For example, PF...

    Authors: Zhenping Wu, Siying Zhang, Lunli Zhang and Ming Li
    Citation: Diagnostic Pathology 2020 15:39
    Content type: Case Report Published on:

  49. Exosomes represent an important subset of extracellular vesicles involved in inter-cellular communications in health and diseases. Exosomes secreted from cancer and immune cells travel to the specific tissues ...

    Authors: Phyoe Kyawe Myint, Eun Jeong Park, Arong Gaowa, Eiji Kawamoto and Motomu Shimaoka
    Citation: Diagnostic Pathology 2020 15:38
    Content type: Commentary Published on:

  50. Numerous studies indicate that higher tumour programmed cell death ligand-1 (PD-L1) expression is associated with greater response to anti-programmed cell death-1 (PD-1)/PD-L1 immunotherapy in non-small cell l...

    Authors: Bharat Jasani, Gudrun Bänfer, Rebecca Fish, Wim Waelput, Yves Sucaet, Craig Barker, Jessica L. Whiteley, Jill Walker, Rudy Hovelinck and Rolf Diezko
    Citation: Diagnostic Pathology 2020 15:37
    Content type: Research Published on:
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Diagnostic Pathology

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