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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. In spite of the multimodal treatment used today, glioblastoma is still the most aggressive and lethal cerebral tumour. To increase survival in these patients, novel therapeutic targets must be discovered. Sign...

    Authors: Sergiu Susman, Radu Pîrlog, Daniel Leucuța, Andrei Otto Mitre, Vlad Adrian Padurean, Carmen Melincovici, Ioana Moldovan, Doinița Crișan and Stefan Ioan Florian
    Citation: Diagnostic Pathology 2019 14:124
    Content type: Research Published on:

  2. Hyperphosphatasia with mental retardation syndrome (HPMRS) is a recessive disorder characterized by high blood levels of alkaline phosphatase together with typical dysmorphic signs such as cleft palate, intell...

    Authors: Layal Abi Farraj, Wassim Daoud Khatoun, Naji Abou Chebel, Victor Wakim, Katia Dawali and Michella Ghassibe-Sabbagh
    Citation: Diagnostic Pathology 2019 14:123
    Content type: Case Report Published on:

  3. Teratocarcinosarcoma (TCS) is a rare aggressive tumor of the nasal cavity and paranasal sinuses and has both epithelial and two or more mesenchymal components. In other organs, 5 cases of ovarian tumors closel...

    Authors: Kozue Ito, Mitsutake Yano, Aiko Ogasawara, Maiko Miwa, Eito Kozawa and Masanori Yasuda
    Citation: Diagnostic Pathology 2019 14:122
    Content type: Case Report Published on:

  5. Protein arginine methyltransferase-1 (PRMT1) is associated with the progression of various tumor types and the process of epithelial to mesenchymal transition (EMT). However, the expression of PRMT1 in renal c...

    Authors: Jelena Filipović, Martina Bosić, Sanja Ćirović, Maja Životić, Duško Dunđerović, Dejan Đorđević, Snežana Živković-Perišić, Aleksandar Lipkovski and Jasmina Marković-Lipkovski
    Citation: Diagnostic Pathology 2019 14:120
    Content type: Research Published on:

  6. Gestational diabetes mellitus (GDM) leads to poor pregnancy outcomes. Strategies that improve trophoblast cell function are important methods for GDM treatment. This study aimed to investigate the expression a...

    Authors: Xuegui Zhou, Cuiping Xiang and Xiaoxia Zheng
    Citation: Diagnostic Pathology 2019 14:119
    Content type: Research Published on:

  7. Carboxypeptidase X, M14 family member 2 (CPXM2), has been associated with several human developmental disorders. However, whether CPXM2 is involved in oncogenesis or tumor progression remains unclear. Currentl...

    Authors: Xin Zhao, Ronghang Li, Qian Wang, Minfei Wu and Yanbing Wang
    Citation: Diagnostic Pathology 2019 14:118
    Content type: Research Published on:

  9. Gastrointestinal stromal tumors (GISTs), a type of mesenchymal tumor in the gastrointestinal tract, are believed to be closely associated with PDGFRA and C-KIT mutations. Schwannoma in the stomach, which is an...

    Authors: Yuxin Li, Yongliang Teng, Xiaofei Wei, Zhuang Tian, Yuqing Cao, Xiaona Liu and Xiumei Duan
    Citation: Diagnostic Pathology 2019 14:116
    Content type: Case Report Published on:

  10. Primary cutaneous CD30+ lymphoproliferative disorders (pc-CD30-LPD) are a group of clonal T cell lymphoproliferative disorders that despite very similar tumor histology follow different and characteristic clin...

    Authors: Cristiane Rúbia Ferreira, Shuchun Zhao, José Antonio Sanches, Denis Miyashiro, Jade Cury-Martins, Raymundo Soares Azevedo, Maria C. N. Zerbini, Yasodha Natkunam and Dita Gratzinger
    Citation: Diagnostic Pathology 2019 14:115
    Content type: Research Published on:

  11. Recent studies have shown that T cell-mediated cellular immune mechanisms play important roles in the progression of hepatitis B to liver cirrhosis, but the underlying mechanisms remain unclear. This present s...

    Authors: Yong-Ting Lan, Zhen-li Wang, Peng Tian, Xiao-Na Gong, Yu-Chen Fan and Kai Wang
    Citation: Diagnostic Pathology 2019 14:114
    Content type: Research Published on:

  12. Rapid (“warm”) autopsies of patients with advanced metastatic cancer provide important insight into the natural history, pathobiology and histomorphology of disease in treatment-resistant tumors. Plasmacytoid ...

    Authors: Caroline T. Simon, Stephanie L. Skala, Paul D. Killen, Javed Siddiqui, Xuhong Cao, Yuanyuan Qiao, Hikmat Al-Ahmadie, Sandra I. Camelo-Piragua, Jeffrey Jentzen, Arul M. Chinnaiyan, Saravana M. Dhanasekaran, Zachery R. Reichert and Rohit Mehra
    Citation: Diagnostic Pathology 2019 14:113
    Content type: Case Report Published on:

  13. Translocation-associated renal cell carcinoma involving ALK (ALK-tRCC) is a rare subtype of adult renal cell carcinoma (RCC) reported in recent years. It was recognized as a group of emerging /provisional RCC ...

    Authors: Jing Yang, Lei Dong, Hong Du, Xiu-bo Li, Yan-xiao Liang and Guo-rong Liu
    Citation: Diagnostic Pathology 2019 14:112
    Content type: Case Report Published on:

  14. Epithelioid sarcoma (ES) is a rare malignant soft tissue tumor, commonly occurring in distal extremities, such as fingers, hands and wrists. For oncologists and surgeons, a female patient with enlarged axillar...

    Authors: Luyan Chen, Li Wang, Xiaochen Zhang, Minya Yao and Peifen Fu
    Citation: Diagnostic Pathology 2019 14:111
    Content type: Case Report Published on:

  15. Low-grade endometrial stromal sarcoma (ESS) is rare mesenchymal neoplasm, recently specified as harboring JAZF1–SUZ12 rearrangement. Typical JAZF1–SUZ12 ESS is slow growing, in which high uptake of fluorodeoxyglu...

    Authors: Koto Fujiishi, Shigenori Nagata, Rieko Kano, Chiaki Kubo, Maasa Shirayanagi, Megumi Ozaki, Takashi Yamamoto, Katsuyuki Nakanishi, Shoji Kamiura and Shin-ichi Nakatsuka
    Citation: Diagnostic Pathology 2019 14:110
    Content type: Case Report Published on:

  16. Laryngeal squamous cell carcinoma (LSCC) is considered to be a common malignancy of the head and neck with poor prognosis for its late diagnosis, metastasis and recurrence. Growing evidence demonstrates that t...

    Authors: Ruihua Fang, Yongjin Huang, Jinghua Xie, Jianzhong Zhang and Xiaobin Ji
    Citation: Diagnostic Pathology 2019 14:109
    Content type: Research Published on:

  17. Mcl-1, an anti-apoptotic member of bcl-2 family, together with cleaved poly (ADC-ribose) polymerase (c-PARP) can serve as a marker of cell apoptosis. Previously we reported that treatment of Mnk inhibitor CGP5...

    Authors: Qiuyuan Wen, Yuting Zhan, Hongmei Zheng, Hongjing Zang, Jiadi Luo, Yuting Zhang, Weiyuan Wang, Juan Feng, Junmi Lu, Lingjiao Chen and Songqing Fan
    Citation: Diagnostic Pathology 2019 14:108
    Content type: Research Published on:

  20. High ERCC1 expression is thought to be related with resistance to chemotherapy based on platinum. The aim of this study was to present our institutional observations regarding to the association of ERCC1 and o...

    Authors: Marina Piljić Burazer, Suzana Mladinov, Antonela Matana, Sendi Kuret, Joško Bezić and Merica Glavina Durdov
    Citation: Diagnostic Pathology 2019 14:105
    Content type: Research Published on:

  21. The category of grade 3 neuroendocrine tumor (NET G3) was newly introduced in the 2017 World Health Organization (WHO 2017) classification of neuroendocrine neoplasms of the pancreas. Pancreatic NET G3 shows a...

    Authors: Kenji Inafuku, Tomoyuki Yokose, Hiroyuki Ito, Daisuke Eriguchi, Joji Samejima, Takuya Nagashima, Haruhiko Nakayama, Masaki Suzuki, Kouzo Yamada and Munetaka Masuda
    Citation: Diagnostic Pathology 2019 14:104
    Content type: Case Report Published on:

  22. The most frequent histological types of rhabdomyosarcoma (RMS) in children are embryonal (ERMS) and alveolar (ARMS) tumours. The majority of ARMS are characterized by the presence of PAX3/7-FOXO1 gene fusion a...

    Authors: Magdalena Kaleta, Anna Wakulińska, Agnieszka Karkucińska-Więckowska, Bożenna Dembowska-Bagińska, Wiesława Grajkowska, Maciej Pronicki and Maria Łastowska
    Citation: Diagnostic Pathology 2019 14:103
    Content type: Research Published on:

  23. Basaloid squamous cell carcinoma (BSCC) is a rare subtype of squamous cell carcinoma with a high rate of distant metastasis. BSCC occurs most commonly in the esophagus, lungs, and head and neck. However, BSCC ...

    Authors: Linxiu Liu, Xuemin Xue and Liyan Xue
    Citation: Diagnostic Pathology 2019 14:102
    Content type: Case Report Published on:

  24. The accurate identification of the tissue of origin is critical for optimal management of cancer patients particularly those who develop multiple malignancies; however, conventional diagnostic methods at times...

    Authors: Chuangzhou Rao, Liangqin Nie, Xiaobo Miao, Analyn Lizaso and Guofang Zhao
    Citation: Diagnostic Pathology 2019 14:101
    Content type: Case Report Published on:

  26. Antibodies targeting the programmed cell death-1 (PD-1)/PD-ligand 1 (PD-1/PD-L1) checkpoint have shown promising clinical activity in patients with advanced urothelial carcinoma (UC). Expression of PD-L1 in UC...

    Authors: Magdalena Zajac, Marietta Scott, Marianne Ratcliffe, Paul Scorer, Craig Barker, Hytham Al-Masri, Marlon C. Rebelatto and Jill Walker
    Citation: Diagnostic Pathology 2019 14:99
    Content type: Research Published on:

  27. Celiac disease (CD) is characterized histologically by inflammation and villous atrophy. Villous atrophy is thought to result from a disruption of epithelial cellular proliferation and death. Epithelial cells ...

    Authors: Michael Lee, Shane Betman, Alina Iuga, Hui-Min Yang, Jude Fleming, Peter H. R. Green, Benjamin Lebwohl and Stephen M. Lagana
    Citation: Diagnostic Pathology 2019 14:98
    Content type: Research Published on:

  29. Ovarian metastatic tumors from lung adenocarcinoma are rare, and a serial study of these tumors is lacking to date. Additionally, a better understanding of the clinicopathological and molecular characteristics...

    Authors: Rui Bi, Qianming Bai, Xiaoli Zhu, Xiaoyu Tu, Xu Cai, Wenhua Jiang, Xiaoli Xu, Shaoxian Tang, Huijuan Ge, Bin Chang, Yufan Cheng, Hualei Gan, Xiaoyan Zhou and Wentao Yang
    Citation: Diagnostic Pathology 2019 14:96
    Content type: Research Published on:

  30. Secretory breast carcinoma is an exceptionally rare type of breast carcinoma. Only 5 cases of pure secretory carcinoma in situ have been reported in English literature. Herein, we reported a rare case of pure ...

    Authors: Ying Yang, Zhiyuan Wang, Guoqing Pan, Shumo Li, Yingying Wu and Liu Liu
    Citation: Diagnostic Pathology 2019 14:95
    Content type: Case Report Published on:

  31. Castleman’s disease (CD) is an uncommon type of benign proliferation of the lymphoid tissue, characterized by local or systemic lymphadenopathy that most frequently appears in the mediastinum; involvement of t...

    Authors: Yunzhu Li, Haixia Zhao, Bingyin Su, Chan Yang, Shurong Li and Wanlei Fu
    Citation: Diagnostic Pathology 2019 14:94
    Content type: Case Report Published on:

  33. A primordial odontogenic tumor (POT) is a rare, benign, mixed epithelial and mesenchymal odontogenic tumor that has been included as a new entity in the latest World Health Organization (WHO) classification (2...

    Authors: Qiaochu Sun, Jae-Seo Lee, Okjoon Kim and Young Kim
    Citation: Diagnostic Pathology 2019 14:92
    Content type: Case Report Published on:

  35. European treatment guidelines for pTa and pT1 urinary bladder urothelial carcinoma depend highly on stage and WHO-grade. Both the WHO73 and the WHO04 grading systems show some intra- and interobserver variabil...

    Authors: Vebjørn Kvikstad, Ok Målfrid Mangrud, Einar Gudlaugsson, Ingvild Dalen, Hans Espeland, Jan P. A. Baak and Emiel A. M. Janssen
    Citation: Diagnostic Pathology 2019 14:90
    Content type: Research Published on:

  36. Follicular dendritic cell sarcoma (FDCS) is a rare malignancy. In addition to the classical histopathologic features, it has also some special morphological variants that can present a challenge in the diagnos...

    Authors: You-Li Wu, Feng Wu, Robinson Ateh Mbako, Yu Zhang, Guang-Jie Duan and Xiao-Chu Yan
    Citation: Diagnostic Pathology 2019 14:89
    Content type: Case Report Published on:

  37. Tumor-to-tumor metastasis (TTM) is a rare but well-documented phenomenon that is defined as metastasis in a histologically distinct tumor. Ovarian mature teratomas (OMTs) can coexist with various cancers by ma...

    Authors: Mitsutake Yano, Tomomi Katoh, Tetsuya Hamaguchi, Eito Kozawa, Mei Hamada, Koji Nagata and Masanori Yasuda
    Citation: Diagnostic Pathology 2019 14:88
    Content type: Case Report Published on:

  38. Following publication of the original article [1], the authors reported an added data on Table 1 in their paper. The original article [1] has been updated.

    Authors: C. Elfgen, B. Papassotiropoulos, Z. Varga, L. Moskovszky, M. Nap, U. Güth, A. Baege, E. Amann, F. Chiesa and C. Tausch
    Citation: Diagnostic Pathology 2019 14:87
    Content type: Correction Published on:

    The original article was published in Diagnostic Pathology 2019 14:58

  39. Solitary fibrous tumour (SFT) is a mesenchymal tumour of fibroblastic type, and it develops in almost any part of the human body. However, according to previous studies, the occurrence of intravascular SFTs is...

    Authors: Jingyuan Fan, Jinfeng Qiu and Qingjun Wei
    Citation: Diagnostic Pathology 2019 14:86
    Content type: Case Report Published on:

  40. At the 3rd week of human embryo, some cell clumps are formed by the hyperplasia of mesenchymal cells at the germ layer of the yolk sac wall. These cell clumps are known as blood islands. The cells in the cente...

    Authors: Jianhong An, Yufeng Zhang, Jiao Luo and Hong Shen
    Citation: Diagnostic Pathology 2019 14:85
    Content type: Case Report Published on:

  41. CRTC1-MAML2 fusion is often detected in low- or intermediate-grade salivary mucoepidermoid carcinoma (MEC), and it is associated with a favorable clinical course. Primary MEC of the liver is an extremely rare,...

    Authors: Jiro Watanabe, Keita Kai, Ken Tanikawa, Mamoru Hiraki, Naohisa Mizukami, Shinichi Aishima, Takafumi Nakano and Hidetaka Yamamoto
    Citation: Diagnostic Pathology 2019 14:84
    Content type: Case Report Published on:

  42. Atypical multinucleated stromal giant cells (MSGCs) are occasionally encountered in the esophagogastric mucosa. This study aims to investigate the origin and clinical association of MSGCs in the upper gastroin...

    Authors: Taha Sachak, Wendy L. Frankel, Christina A. Arnold and Wei Chen
    Citation: Diagnostic Pathology 2019 14:83
    Content type: Research Published on:

  43. Hydroa vacciniforme-like lymphoproliferative disorder (HV-LPD) is a cutaneous form of chronic active Epstein-Barr virus (EBV) infection, which occurs mainly in children in Latin America and Asia. It can progre...

    Authors: Na Guo, Yueqiong Chen, Yu Wang, Yuhua Huang, Yanfen Feng, Min Li and Huilan Rao
    Citation: Diagnostic Pathology 2019 14:82
    Content type: Research Published on:

  44. The poor outcome of high-grade B-cell lymphoma, with rearrangements of MYC, BCL2 and/or BCL6, also known as double-hit lymphoma or triple-hit lymphoma (DHL or THL), has been well documented, while the clinical...

    Authors: Sixia Huang, Lin Nong, Wei Wang, Li Liang, Yalin Zheng, Jumei Liu, Dong Li, Xin Li, Bo Zhang and Ting Li
    Citation: Diagnostic Pathology 2019 14:81
    Content type: Research Published on:

  45. Panniculitis-like T-cell lymphoma is an uncommon type of non-Hodgkin lymphoma, occurring usually in the form of nodules within the subcutaneous fat tissue of the extremities or trunk. In the literature, subcut...

    Authors: Jan Hrudka, Václav Eis, Josef Heřman, Zuzana Prouzová, Andreas Rosenwald and František Duška
    Citation: Diagnostic Pathology 2019 14:80
    Content type: Case Report Published on:

  46. Pseudomyogenic hemangioendothelioma (PHE)/epithelioid sarcoma-like hemangioendothelioma (ES-H) is a rare vascular tumor of intermediate malignancy that commonly occurs in soft tissue of distal extremities of y...

    Authors: Yan Ge, Xingtao Lin, Fen Zhang, Fangping Xu, Luqiao Luo, Weiye Huang, Zhihua Liu, Yanhui Liu and Zhi Li
    Citation: Diagnostic Pathology 2019 14:79
    Content type: Case Report Published on:

  47. Adenoid cystic carcinoma (ACC) is a slow growing salivary gland malignancy that is molecularly characterized by t(6:9)(q22–23;p23–24) translocations which predominantly result in MYB-NFIB gene fusions in nearly h...

    Authors: John B. McIntyre, Jenny J. Ko, Jodi Siever, Angela M. Y. Chan, Roderick H. W. Simpson, Desiree Hao and Harold Y. Lau
    Citation: Diagnostic Pathology 2019 14:78
    Content type: Research Published on:

  48. Neurofibromatosis type-1 (NF1), also called von Recklinghausen disease, is a rare genetic disease which can lead to the development of benign or even malignant tumors. NF1 is mostly diagnosed in children or ea...

    Authors: Karolina Poredska, Lumir Kunovsky, Vladimir Prochazka, Jiri Dolina, Miroslava Chovancova, Jakub Vlazny, Tomas Andrasina, Michal Eid, Petr Jabandziev, Petr Kysela and Zdenek Kala
    Citation: Diagnostic Pathology 2019 14:77
    Content type: Case Report Published on:

  49. This study aims to provide genetic diagnoses for 30 cases of fetal skeletal dysplasia, and a molecular basis for the future prenatal diagnosis of fetal skeletal dysplasia.

    Authors: Yan Liu, Li Wang, Yi-Ke Yang, Ying Liang, Tie-Juan Zhang, Na Liang, Li-Man Yang, Si-Jing Li, Dan Shan and Qing-Qing Wu
    Citation: Diagnostic Pathology 2019 14:76
    Content type: Research Published on:

  50. The bone formation within bladder tumors could be encountered in 3 conditions. These might consist of malignant bone formation in mesenchymal tumors; mixed mesenchymal and epithelial tumors; and epithelial tum...

    Authors: Joëlle Razafimahefa, Clément Gosset, Pierre Mongiat-Artus, Tsitohery Francine Andriamampionona and Jérôme Verine
    Citation: Diagnostic Pathology 2019 14:75
    Content type: Case Report Published on:
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