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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. MicroRNA-224 has been proven dysregulated in some human malignancies and correlated with tumor progression. However, its expression and clinical significance in non-small cell lung cancer (NSCLC) is still uncl...

    Authors: Dan Zhu, Hui Chen, Xiguang Yang, Weisong Chen, Linying Wang, Jilin Xu and Long Yu
    Citation: Diagnostic Pathology 2014 9:198
    Content type: Research Published on:

    The Correction to this article has been published in Diagnostic Pathology 2019 14:50

  3. Recent studies observed that altered energy metabolism has become widespread in cancer cells along with other cancer-associated traits that have been accepted as hallmarks of cancer. Akt signaling pathway is i...

    Authors: Bo Wang, Fei Sun, Nan Dong, Zhenguo Sun, Yi Diao, Cheng Zheng, Jianxin Sun, Yang Yang and Dehua Jiang
    Citation: Diagnostic Pathology 2014 9:211
    Content type: Research Published on:

  4. Chronic obstructive pulmonary disease presents with two different phenotypes: chronic bronchitis and emphysema with parenchymal destruction. Decreased expression of vascular endothelial growth factor and incre...

    Authors: Paul Zarogoulidis, Wolfgang Hohenforst-Schmidt, Haidong Huang, Despoina Sahpatzidou, Lutz Freitag, Leonidas Sakkas, Aggeliki Rapti, Ioannis Kioumis, Georgia Pitsiou, Kokkona Kouzi-Koliakos, Anna Papamichail, Antonis Papaiwannou, Theodora Tsiouda, Kosmas Tsakiridis, Konstantinos Porpodis, Sofia Lampaki…
    Citation: Diagnostic Pathology 2014 9:195
    Content type: Research Published on:

  5. To validate the expression of a urine-based bladder cancer associated diagnostic signature comprised of 10 targets; ANG, CA9, MMP9, MMP10, SERPINA1, APOE, SDC1, VEGFA, SERPINE1 and IL8 in bladder tumor tissues.

    Authors: Ge Zhang, Evan Gomes-Giacoia, Yunfeng Dai, Adrienne Lawton, Makito Miyake, Hideki Furuya, Steve Goodison and Charles J Rosser
    Citation: Diagnostic Pathology 2014 9:200
    Content type: Research Published on:

  6. Lung cancer has been considered as one of the most important causes of cancer-related mortality worldwide. To predict lung cancer, researchers identified several molecular markers. However, many underlying mar...

    Authors: Zongjuan Ming, Chunli Guo, Meihua Jiang, Wei Li, Yuping Zhang, Na Fan, Yujie Zhong, Xia Meng and Shuanying Yang
    Citation: Diagnostic Pathology 2014 9:201
    Content type: Research Published on:

  7. Cervical cancer is one of the most common cancers affecting women worldwide. It is well established that human papilloma virus (HPV) infection is the prime risk factor in the development of cervical cancer. Th...

    Authors: Purushotham Krishnappa, Ibtisam Binti Mohamad, Yip Jo Lin and Ankur Barua
    Citation: Diagnostic Pathology 2014 9:202
    Content type: Research Published on:

  8. Whole slide images (WSIs) used in medical education can provide new insights into how histological slides are viewed by students. We created software infrastructure which tracks viewed WSI areas, used it durin...

    Authors: Slawomir Walkowski, Mikael Lundin, Janusz Szymas and Johan Lundin
    Citation: Diagnostic Pathology 2014 9:208
    Content type: Research Published on:

  9. To analyze the clinicopathologic factors associated with mucosal and submucosal infiltration in differentiated depressed early gastric cancer, and screening factors that can predict depth of infiltration befor...

    Authors: Shu-dong Yang, Zhi-xin Qian, Qiang Zhan, Qun-yan Zhou and Guo-min Lu
    Citation: Diagnostic Pathology 2014 9:206
    Content type: Research Published on:

  10. Maspin is a 42 kDa protein known to act as a tumor suppressor. Although its function has not been fully elucidated, numerous reports have investigated the prognostic impact of maspin in patients with several t...

    Authors: Chikako Takeda, Yuzo Takagi, Tatsushi Shiomi, Kanae Nosaka, Hideki Yamashita, Mari Osaki, Koji Endo, Takeshi Minamizaki, Ryota Teshima, Hideki Nagashima and Yoshihisa Umekita
    Citation: Diagnostic Pathology 2014 9:205
    Content type: Research Published on:

  11. Papillary thyroid carcinoma is rarely associated with metastatic disease. The most common sites of metastasis are the lungs and bones, while only few cases of ovarian metastasis are described in literature.

    Authors: Giacomo Corrado, Giulia Pomati, Andrea Russo, Paolo Visca, Cristina Vincenzoni, Lodovico Patrizi and Enrico Vizza
    Citation: Diagnostic Pathology 2014 9:193
    Content type: Case Report Published on:

  12. Benign lymphangioendothelioma (BL) represents a very rare lymphatic vascular proliferation. Our aim is to be aware that owing to its characteristic features, pathologists can easily misinterpret it as cutaneou...

    Authors: Sohsuke Yamada, Yoko Yamada, Miwa Kobayashi, Ryosuke Hino, Aya Nawata, Hirotsugu Noguchi, Motonobu Nakamura and Toshiyuki Nakayama
    Citation: Diagnostic Pathology 2014 9:197
    Content type: Case Report Published on:

  13. Gene expression analysis is powerful for investigating the underlying mechanisms of Duchenne muscular dystrophy (DMD). Previous studies mainly neglected co-expression or transcription factor (TF) information. ...

    Authors: Lijun Tian, Junhua Cao, Xingqiang Deng, Chuanling Zhang, Tong Qian, Xianxiang Song and Baoshan Huang
    Citation: Diagnostic Pathology 2014 9:210
    Content type: Research Published on:

  14. N-Myc downstream-regulated gene 2 (NDRG2), as a tumor suppressor, has been demonstrated to inhibit tumor invasion and migration of hepatocellular carcinoma (HCC) by reducing the expression of CD24, which has b...

    Authors: Bing Li, Qing Shao, Dong Ji, Fan Li, Xiaodong Guo and Guofeng Chen
    Citation: Diagnostic Pathology 2014 9:209
    Content type: Research Published on:

  15. Medullary carcinoma is a rare type of colon cancer with characteristic clinical and molecular features. Notably, despite its high-grade histology, the prognosis is generally better than for colonic adenocarcin...

    Authors: Andrew Mitchell and Yves Bendavid
    Citation: Diagnostic Pathology 2014 9:204
    Content type: Case Report Published on:

  16. The modification of stromal components with the disappearance of CD34 positive fibrocytes and by contrast the acquisition of smooth-muscle actin positive myofibroblasts is a frequent event in breast carcinomas...

    Authors: Xavier Catteau, Philippe Simon and Jean-Christophe Noël
    Citation: Diagnostic Pathology 2014 9:196
    Content type: Research Published on:

  17. There is a worldwide debate involving clinicians, uropathologists as well as patients and their families on whether Gleason score 6 adenocarcinoma should be labelled as cancer.

    Authors: Rodolfo Montironi, Marina Scarpelli, Roberta Mazzucchelli, Antonio Lopez-Beltran, Matteo Santoni, Alberto Briganti, Francesco Montorsi and Liang Cheng
    Citation: Diagnostic Pathology 2014 9:190
    Content type: Case Report Published on:

  18. Malaria is the most common disease transmitted by the bite by an infected female anopheles mosquito and caused by the plasmodium parasite. It is mostly prevalent in subtropical regions receiving abundant rain ...

    Authors: Vadivel Masilamani, Sandhanasamy Devanesan, Mani Ravikumar, Kantharaj Perinbam, Mohamad Saleh AlSalhi, Saradh Prasad, Siddanna Palled, Kadirampatti Mani Ganesh and Abbas Habeeb Alsaeed
    Citation: Diagnostic Pathology 2014 9:182
    Content type: Research Published on:

  19. The histopathologic distinction between typical carcinoid (TC) and atypical carcinoid (AC) of the lung is based largely on mitotic index. Ki-67 may aid in separation of these tumors, as well as the distinction...

    Authors: Sandy Z Liu, Paul N Staats, Lindsay Goicochea, Borislav A Alexiev, Nirav Shah, Renee Dixon and Allen P Burke
    Citation: Diagnostic Pathology 2014 9:174
    Content type: Research Published on:

  20. Interleukin-22 (IL-22) is a member of the IL-10 family of anti-inflammatory cytokines that mediates epithelial immunity. IL-22 expression was found to be increased in patients with ulcerative colitis (UC). Whethe...

    Authors: Hong Gang Chi, Xue Bao Zheng, Zhu Guo Wu, Shi Xue Dai, Zheng Wan and Ying Zou
    Citation: Diagnostic Pathology 2014 9:183
    Content type: Research Published on:

  21. Thyroid-like follicular carcinoma of the kidney is an extremely rare histological variant of renal cell carcinoma. It was described only recently and is not included in the World Health Organization classifica...

    Authors: Merieme Ghaouti, Laurence Roquet, Maximilien Baron, Christian Pfister and Jean-Christophe Sabourin
    Citation: Diagnostic Pathology 2014 9:186
    Content type: Case Report Published on:

  23. Reduced membranous expression of the cytoskeleton-associated protein ezrin has previously been demonstrated to correlate with poor prognosis in urothelial bladder cancer in several independent studies. The pre...

    Authors: Christoffer Wennersten, Gustav Andersson, Karolina Boman, Björn Nodin, Alexander Gaber and Karin Jirström
    Citation: Diagnostic Pathology 2014 9:189
    Content type: Research Published on:

  24. Primary pulmonary lymphoma (PPL) is rare and easily misdiagnosed because of the lack of typical clinical features. It most commonly involves elderly patients aged between 60 and 70 years, and pathological diag...

    Authors: Jin Zhu, Yingmei Wang, Li Gong and Gaosheng Huang
    Citation: Diagnostic Pathology 2014 9:188
    Content type: Case Report Published on:

  25. Trochanteric fractures (TF) have become a major source of morbidity and mortality in elderly. We conducted this study to compare the outcomes of unstable trochanteric fractures treated with the InterTan nail a...

    Authors: Dankai Wu, Guangkai Ren, Chuangang Peng, Xuanlin Zheng, Fengmin Mao and Yueyang Zhang
    Citation: Diagnostic Pathology 2014 9:191
    Content type: Research Published on:

  26. Numerous clinical studies have shown that anti-EGFR therapies are effective only in a subset of patients with colorectal cancer. Mutations in the KRAS and BRAF genes have been confirmed as negative predictors ...

    Authors: Daniela Martinetti, Rosario Costanzo, Shahin Kadare, Mehdiu Alimehmeti, Cristina Colarossi, Vincenzo Canzonieri, Massimiliano Berretta and Lorenzo Memeo
    Citation: Diagnostic Pathology 2014 9:187
    Content type: Research Published on:

  27. Individuals born with a low birth weight (LBW) have a higher risk of developing kidney dysfunction during their lifetime and sometimes exhibit focal segmental glomerulosclerosis (FSGS) lesions in their glomeru...

    Authors: Toshiyuki Imasawa, Masashi Tanaka, Naoki Maruyama, Takehiko Kawaguchi, Yutaka Yamaguchi, Rodrigue Rossignol, Hiroshi Kitamura and Motonobu Nishimura
    Citation: Diagnostic Pathology 2014 9:181
    Content type: Research Published on:

  29. Recent studies have linked chemotherapy resistance to the altered expression of microRNAs (miRNAs). Thus, miRNA-based approaches to modulating sensitivity to temozolomide (TMZ) may overcome chemoresistance. Th...

    Authors: Hao Wu, Qiang Liu, Tao Cai, Yu-dan Chen, Fan Liao and Zhi-fei Wang
    Citation: Diagnostic Pathology 2014 9:173
    Content type: Research Published on:

  30. Alkaptonuria (AKU) is an inborn error of catabolism due to a deficient activity of homogentisate 1,2-dioxygenase. Patients suffer from a severe arthropathy, cardiovascular and kidney disease but other organs a...

    Authors: Lia Millucci, Lorenzo Ghezzi, Giulia Bernardini, Daniela Braconi, Pietro Lupetti, Federico Perfetto, Maurizio Orlandini and Annalisa Santucci
    Citation: Diagnostic Pathology 2014 9:185
    Content type: Research Published on:

  31. Many epidemiological studies have suggested an association between estrogen receptor-beta (ER-β) polymorphisms with endometriosis risk. However, the results of these studies have been inconsistent. In the pres...

    Authors: Renyong Guo, Nengneng Zheng, Shiping Ding, Ying Zheng and Limin Feng
    Citation: Diagnostic Pathology 2014 9:184
    Content type: Research Published on:

  32. Recent studies have demonstrated that microRNA-22 (miR-22) was deregulated in many types of cancers and was involved in various cellular processes related to carcinogenesis. However, the clinical significance ...

    Authors: Wei-na Wan, Yu-qin Zhang, Xue-mei Wang, Yan-jun Liu, Yi-xia Zhang, Yan-hong Que, Wen-jing Zhao and Ping Li
    Citation: Diagnostic Pathology 2014 9:178
    Content type: Research Published on:

  33. Genetic factors plays an important role in early failure of total hip arthroplasty (THA) etiology and MMP-1 gene polymorphism rs5854 may be involved. The present study was conducted to reveal the possible asso...

    Authors: Yiguo Yan, Jianzhong Hu, Hongbin Lu and Wenjun Wang
    Citation: Diagnostic Pathology 2014 9:177
    Content type: Research Published on:

  34. To identify critical genes and biological pathways in acute lung injury (ALI), a comparative analysis of gene expression profiles of patients with ALI + sepsis compared with patients with sepsis alone were per...

    Authors: Zhiqiang Guo, Chuncheng Zhao and Zheng Wang
    Citation: Diagnostic Pathology 2014 9:176
    Content type: Research Published on:

    The Retraction Note to this article has been published in Diagnostic Pathology 2015 10:51

  35. The relationship between homocysteine (Hcy) and diabetic retinopathy (DR) remains unclear to date. Therefore, a systematic review and meta-analysis was performed on the relationship between Hcy level and DR.

    Authors: Chong Xu, Yan Wu, Guodong Liu, Xiaoqiang Liu, Fang Wang and Jing Yu
    Citation: Diagnostic Pathology 2014 9:167
    Content type: Original article Published on:

  36. Prostate cancer (PCa) is a biologically heterogeneous disease with considerable variation in clinical aggressiveness. In this study, bioinformatics was used to detect the patterns of gene expression alteration...

    Authors: Jiling Wen, Rongbing Li, Xiaofei Wen, Guangming Chou, Jiasun Lu, Xuelei Wang and Yongchao Jin
    Citation: Diagnostic Pathology 2014 9:156
    Content type: Research Published on:

    The Retraction Note to this article has been published in Diagnostic Pathology 2015 10:11

  37. Intraductal tubular adenoma of the pancreas, pyloric gland type (ITA), is an infrequent intraductal benign lesion located in the main duct and large branch duct of the pancreas. The purpose of this report is t...

    Authors: Xiaoyan Chang, Ying Jiang, Ji Li and Jie Chen
    Citation: Diagnostic Pathology 2014 9:172
    Content type: Research Published on:

  38. Nucleolin, as a multifunctional protein, has been demonstrated to play an oncogenic role in human hepatocellular carcinoma (HCC). The aim of this study was to investigate the expression pattern of nucleolin in...

    Authors: XiaoDong Guo, Lu Xiong, Lingxiang Yu, Ruisheng Li, ZhaoHai Wang, Bo Ren, JingHui Dong, Boan Li and Dadong Wang
    Citation: Diagnostic Pathology 2014 9:175
    Content type: Research Published on:

  39. Gastric polyps (GP) are characterised by luminal overgrowths projecting above the plane of the mucosal surface that can be classified as non-neoplastic and neoplastic lesions. In humans, recent studies have dr...

    Authors: Irina Amorim, Marian A Taulescu, Andreia Ferreira, Alexandra Rêma, Celso A Reis, Augusto M Faustino, Cornel Cătoi and Fátima Gärtner
    Citation: Diagnostic Pathology 2014 9:166
    Content type: Short report Published on:

  40. Epidermal Growth Factor Receptor (EGFR) targeting therapies are currently of great relevance for the treatment of lung cancer. For this reason, in addition to mutational analysis immunohistochemistry (IHC) of ...

    Authors: Rania Gaber, Iris Watermann, Christian Kugler, Nils Reinmuth, Rudolf M Huber, Philipp A Schnabel, Ekkehard Vollmer, Martin Reck and Torsten Goldmann
    Citation: Diagnostic Pathology 2014 9:165
    Content type: Research Published on:

  41. Association between Cyclin D1 (CCND1) polymorphism and cervical cancer risk are conflicting with published articles. We performed a meta-analysis to investigate the association between CCND1 G870A polymorphism...

    Authors: Yuan-Yuan Hu, Rong Zheng, Chong Guo and Yu-Ming Niu
    Citation: Diagnostic Pathology 2014 9:168
    Content type: Methodology Published on:

  42. miRNAs are involved in coordinating a variety of cellular processes by regulating their target genes. Aberrant expression of miRNAs is correlated with various cancers. Previous studies have shown that miR-337 ...

    Authors: Rui Zhang, Hong Leng, Junwen Huang, Yuwen Du, Yuanyuan Wang, Wenqiao Zang, Xiaonan Chen and Guoqiang Zhao
    Citation: Diagnostic Pathology 2014 9:171
    Content type: Research Published on:

  43. Primay spleen NK/T cell lymphoma is very rare. We report a case of 39-years-old male of primary splenic NK/T cell lymphoma with bone marrow involvement and CD30 positive expression.

    Authors: Qinghua Cao, Yan Huang, Ziyin Ye, Ni Liu, Shuhua Li and Tingsheng Peng
    Citation: Diagnostic Pathology 2014 9:169
    Content type: Case Report Published on:

  44. Low-grade fibromyxoid sarcoma (LGFMS) is a rare soft tissue tumor typically affecting young to middle-aged adults. Despite its otherwise benign histologic appearance and indolent nature, it can have fully mali...

    Authors: Aiko Kurisaki-Arakawa, Yoshiyuki Suehara, Atsushi Arakawa, Tatsuya Takagi, Michiko Takahashi, Keiko Mitani, Kazuo Kaneko, Takashi Yao and Tsuyoshi Saito
    Citation: Diagnostic Pathology 2014 9:163
    Content type: Case Report Published on:

  45. The biological processes and molecular mechanisms underlying miR-107 remain unclear in gastric cancer(GC). In this study, we aimed to investigate the expression, biological functions and mechanisms of miR-107 ...

    Authors: Yan-qiang Song, Xu-hui Ma, Gui-liang Ma, Bin Lin, Chao Liu, Quan-jiang Deng and Wen-ping Lv
    Citation: Diagnostic Pathology 2014 9:164
    Content type: Research Published on:

  46. Lymphomas are common malignancies that have various subtypes with many overlapping histologic, immunophenotypic and genetic features. Therefore, discordance in classifying lymphoma among pathologists may be en...

    Authors: Tawatchai Pongpruttipan, Sanya Sukpanichnant, Thamathorn Assanasen, Lertlakana Bhoopat, Kanita Kayasut, Wasana Kanoksil and Pongsak Wannakrairot
    Citation: Diagnostic Pathology 2014 9:162
    Content type: Research Published on:

  47. The usefulness of serological tests for detection of P. aeruginosa pulmonary infection in cystic fibrosis (CF) is controversial. Here, we assessed the value of detecting anti-P. aeruginosa IgG by a quantitative e...

    Authors: Renan Marrichi Mauch, Cláudio Lúcio Rossi, José Dirceu Ribeiro, Antínio Fernando Ribeiro, Marcos Tadeu Nolasco da Silva and Carlos Emílio Levy
    Citation: Diagnostic Pathology 2014 9:158
    Content type: Research Published on:

  49. Whether microRNA-130b(miR-130b) can serve as a prognostic biomarker of hepatocellular carcinoma (HCC) has not been investigated. In the present study, we investigated the feasibility of miR-130b as a novel pro...

    Authors: Wen-yao Wang, Hong-fei Zhang, Lei Wang, Yan-peng Ma, Fei Gao, Shao-jun Zhang and Li-chao Wang
    Citation: Diagnostic Pathology 2014 9:160
    Content type: Research Published on:

  50. The different expression level of Dickkopf-1 (DKK-1) in different cancers shows that the function of DKK-1 depends on the histological type of the cancer cells and the tissue microenvironment. To our knowledge...

    Authors: Shao-jie Zhou, Shou-rong Zhuo, Xiao-qing Yang, Chun-xin Qin and Zi-liang Wang
    Citation: Diagnostic Pathology 2014 9:161
    Content type: Research Published on:
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    Journal Impact Factor: 2.4
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Diagnostic Pathology

ISSN: 1746-1596

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