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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. The importance of cell-cell junction proteins (including armadillo proteins) in tumor biology is known, but limited with regard to plakophilins. We explored the relationship between plakophilins (PKP1, PKP2, P...

    Authors: Guzin G Demirag, Yurdanur Sullu, Dilek Gurgenyatagi, Nilgun O Okumus and Idris Yucel
    Citation: Diagnostic Pathology 2011 6:1
    Content type: Research Published on:

  3. Breast metastasis from extra-mammary malignancy is rare. Based on the literature an incidence of 0.4-1.3% is reported. The primary malignancies most commonly metastasizing to the breast are leukemia-lymphoma, ...

    Authors: Nicoletta Maounis, Maria Chorti, Stella Legaki, Eleni Ellina, Aphrodite Emmanouilidou, Maria Demonakou and Xanthi Tsiafaki
    Citation: Diagnostic Pathology 2010 5:82
    Content type: Case Report Published on:

  4. A 27-year-old female white-collar worker was diagnosed in 1998 with mesothelioma eight and one-half years following first exposure as a bystander to debris in a site in which asbestos-containing building mater...

    Authors: Enrique Bitchatchi, Klaus Kayser, Marina Perelman and Elihu D Richter
    Citation: Diagnostic Pathology 2010 5:81
    Content type: Case Report Published on:

  5. Selenium has been shown to inhibit cancer development and growth through the mediation of selenium-binding proteins. Decreased expression of selenium-binding protein 1 has been reported in cancers of the prost...

    Authors: Peng Zhang, Cunxian Zhang, Xudong Wang, Fang Liu, C James Sung, M Ruhul Quddus and W Dwayne Lawrence
    Citation: Diagnostic Pathology 2010 5:80
    Content type: Research Published on:

  6. The purpose of this study was to (1) identify specific miRNAs in growth hormones (GH)-secreting pituitary adenomas; (2) determine the relationship between the expression of these miRNAs and tumor size, somatos...

    Authors: Zhi-Gang Mao, Dong-Sheng He, Jing Zhou, Bin Yao, Wei-Wei Xiao, Chun-Hua Chen, Yong-Hong Zhu and Hai-Jun Wang
    Citation: Diagnostic Pathology 2010 5:79
    Content type: Research Published on:

  7. Ovarian cancer is the second most common cancer of the female genital tract in the United Kingdom (UK), accounting for 6% of female deaths due to cancer. This cancer is associated with poor survival and there ...

    Authors: Viren Asher, Raheela Khan, Averil Warren, Robert Shaw, Gerhard V Schalkwyk, Anish Bali and Heidi M Sowter
    Citation: Diagnostic Pathology 2010 5:78
    Content type: Research Published on:

  9. Metaplastic breast carcinoma (MBC) is a rare subtype of breast cancer characterized by coexistence of carcinomatous and sarcomatous components. Snail is a nuclear transcription factor incriminated in the trans...

    Authors: Aziza Nassar, Nicole Sookhan, Marta Santisteban, Sandra C Bryant, Judy C Boughey, Tamar Giorgadze and Amy Degnim
    Citation: Diagnostic Pathology 2010 5:76
    Content type: Research Published on:

  10. We assessed the expression of cytokeratin (CK) and apomucin (MUC) in ampullary carcinoma (AC) to develop a system for the classification of ACs on the basis of their clinical significance.

    Authors: Yasunari Kawabata, Tsuneo Tanaka, Takashi Nishisaka, Touko Inao, Takeshi Nishi and Seiji Yano
    Citation: Diagnostic Pathology 2010 5:75
    Content type: Research Published on:

  11. Altered sialylation has been observed during oncogenic transformation. Sialylated oligosaccharides of glycoproteins and glycolipids have been implicated in tumor progression and metastases. In the cervical can...

    Authors: Dolores López-Morales, Julio Reyes-Leyva, Gerardo Santos-López, Edgar Zenteno and Verónica Vallejo-Ruiz
    Citation: Diagnostic Pathology 2010 5:74
    Content type: Research Published on:

  12. The spreading of whole slide imaging or digital slide systems in pathology as an innovative technique seems to be unstoppable. Successful introduction of digital slides in education has played a crucial role t...

    Authors: László Fónyad, László Gerely, Mária Cserneky, Béla Molnár and András Matolcsy
    Citation: Diagnostic Pathology 2010 5:73
    Content type: Research Published on:

  13. This study aims to analyze immunocytochemically p53 aberrant expression and mdm-2 expression in primary and recurrent mucoepidermoid carcinoma (MEC) of parotid gland and to ascertain if expression of these mar...

    Authors: Ehab S Abd-Elhamid and Mohamed H Elmalahy
    Citation: Diagnostic Pathology 2010 5:72
    Content type: Research Published on:

  15. A persistent goal of oncologic histochemistry is to microscopically identify neoplasia tinctorially. Consequently, the newly developed CellDetect® staining technology, that appears to exhibit this property, warra...

    Authors: Pavel Idelevich, Adi Elkeles, Elimelech Okon, Don Kristt, Dov Terkieltaub, Ilia Rivkin, Ilan Bruchim and Ami Fishman
    Citation: Diagnostic Pathology 2010 5:70
    Content type: Research Published on:

  16. Although the diagnosis of chondrosarcoma, especially the distinction between enchondroma and low-grade chondrosarcoma or low-grade chondrosarcoma and high-grade chondrosarcoma, is pathologically difficult, dif...

    Authors: Michihisa Zenmyo, Akihide Tanimoto, Harutoshi Sakakima, Masahiro Yokouchi, Satoshi Nagano, Takuya Yamamoto, Yasuhiro Ishido, Setsuro Komiya and Kosei Ijiri
    Citation: Diagnostic Pathology 2010 5:69
    Content type: Research Published on:

  17. We report a case of a rare complication of Laparoscopic Adjustable Gastric Banding (LAGB) as a cause of death in the immediate post-operative period. The number of relevant reports and postmortem images presen...

    Authors: Kleio Fragkouli, Antigoni Mitselou and Theodore Vougiouklakis
    Citation: Diagnostic Pathology 2010 5:68
    Content type: Short report Published on:

  19. Colorectal tumors mostly arise from sporadic adenomatous polyps. Polyps are defined as a mass of cells that protrudes into the lumen of the colon. Adenomatous polyps are benign neoplasms that, by definition di...

    Authors: Sharifeh Mehrabi, Joyce A Akwe, Gregory Adams Jr, William Grizzle, Xuebiao Yao and Felix O Aikhionbare
    Citation: Diagnostic Pathology 2010 5:66
    Content type: Short report Published on:

  20. Lysosomal storage diseases (LSD) are inherited disorders caused by deficiency of lysosomal enzymes in which early diagnosis is essential to provide timely treatment. This study reports interval values for the ...

    Authors: Karen B Müller, Mayra DB Rodrigues, Vanessa G Pereira, Ana M Martins and Vânia D'Almeida
    Citation: Diagnostic Pathology 2010 5:65
    Content type: Research Published on:

  21. Glypican-3 (GPC3) is a membrane-bound heparan sulfate proteoglycan that functions in embryonic cell growth and differentiation and is highly expressed in the placenta. GPC3 is mutated in Simpson-Golabi-Behmel ...

    Authors: Robin J Ou-Yang, Pei Hui, Ximing J Yang and Debra L Zynger
    Citation: Diagnostic Pathology 2010 5:64
    Content type: Research Published on:

  23. Giant cell tumor (GCT) of bone is a locally destructive tumor that occurs predominantly in long bones of post-pubertal adolescents and young adults, where it occurs in the epiphysis. The majority are treated b...

    Authors: Ira J Miller, Alan Blank, Suellen M Yin, Allison Mcnickle, Robert Gray and Steven Gitelis
    Citation: Diagnostic Pathology 2010 5:62
    Content type: Case Report Published on:

  26. Gliomas are a very rare subtype of pineal region tumours, whereas oligodendrogliomas of the pineal region are exceedingly rare, since there have been only 3 cases of anaplastic oligodedrogliomas reported this ...

    Authors: Georgia Levidou, Penelope Korkolopoulou, George Agrogiannis, Nikolaos Paidakakos, Dimos Bouramas and Efstratios Patsouris
    Citation: Diagnostic Pathology 2010 5:59
    Content type: Case Report Published on:

  27. Hepatoma-derived growth factor (HDGF) is involved in the hepatocarcinogenesis. In this study, we investigated the HDGF expression in hepatocellular carcinoma (HCC) and its correlation with clinicopathologic fe...

    Authors: Yanyan Zhou, Nanxiang Zhou, Weiyi Fang and Jirong Huo
    Citation: Diagnostic Pathology 2010 5:58
    Content type: Research Published on:

  28. Meningoencephalitis by Herpesvirus type 5 (BoHV-5) in cattle has some features that are similar to those of herpetic encephalitis in humans and other animal species. Human Herpesvirus 3 (commonly known as Varicel...

    Authors: Tereza C Cardoso, Heitor F Ferrari, Andrea F Garcia, Livia C Bregano, Alexandre L Andrade and Adriana HC Nogueira
    Citation: Diagnostic Pathology 2010 5:57
    Content type: Short report Published on:

  29. Cushing's Syndrome (CS) which is caused by isolated Corticotropin-releasing hormone (CRH) production, rather than adrenocorticotropin (ACTH) production, is extremely rare.

    Authors: Sadeka Shahani, Rodolfo J Nudelman, Ramaswami Nalini, Han-Seob Kim and Susan L Samson
    Citation: Diagnostic Pathology 2010 5:56
    Content type: Case Report Published on:

  30. Breast carcinoma with osteoclastic giant cells (OGCs) is characterized by multinucleated OGCs, and usually displays inflammatory hypervascular stroma. OGCs may derive from tumor-associated macrophages, but the...

    Authors: Yukiko Shishido-Hara, Atsushi Kurata, Masachika Fujiwara, Hiroki Itoh, Shigeru Imoto and Hiroshi Kamma
    Citation: Diagnostic Pathology 2010 5:55
    Content type: Case Report Published on:

  31. Presence of lobular intraepithelial neoplasia (LIN) is not routinely reported as part of margin assessment in breast conservation therapy (BCT) as in ductal carcinoma in situ (DCIS). With new emerging evidence...

    Authors: Sophia K Apple, Mahan Matin, Eric P Olsen and Neda A Moatamed
    Citation: Diagnostic Pathology 2010 5:54
    Content type: Research Published on:

  32. Inflammatory myofibroblastic pseudotumours of the liver are rare tumour-like lesions that can mimic malignant liver neoplasms. The symptoms and radiological findings of this rare tumour can pose diagnostic dif...

    Authors: Talal Al-Jabri, Pandanaboyana Sanjay, Irshad Shaikh and Alan Woodward
    Citation: Diagnostic Pathology 2010 5:53
    Content type: Case Report Published on:

  33. Sclerosing rhabdomyosarcoma (SRMS) is an infrequent variant of rhabdomyosarcoma characterized by extensive intercellular hyaline fibrosis. We report the case of a 37 year-old male with a 9 × 6 cm SRMS on the r...

    Authors: Miguel Martorell, Cristian M Ortiz and Jose Angel Garcia
    Citation: Diagnostic Pathology 2010 5:52
    Content type: Case Report Published on:

  34. Adrenocortical carcinosarcoma is an extremely rare and aggressive variant of adrenocortical carcinoma characterized by the presence of both carcinomatous and sarcomatous components, with the latter often showi...

    Authors: Kotaro Sasaki, Marisa Desimone, Harsha R Rao, George J Huang and Raja R Seethala
    Citation: Diagnostic Pathology 2010 5:51
    Content type: Case Report Published on:

  36. The understanding of the cellular responses implicated in perinatal brain damages and the characterization of the various mechanisms involved might open new horizons for understanding the time of onset of a br...

    Authors: Irene Riezzo, Margherita Neri, Francesco De Stefano, Ezio Fulcheri, Francesco Ventura, Cristoforo Pomara, Roberto Rabozzi, Emanuela Turillazzi and Vittorio Fineschi
    Citation: Diagnostic Pathology 2010 5:49
    Content type: Research Published on:

  37. Although tissue microarrays (TMAs) are commonly employed in clinical and basic-science research, there are no guidelines for evaluating the appropriateness of a TMA for a given biomarker and tumor type. Furthe...

    Authors: Jeanette E Eckel-Passow, Christine M Lohse, Yuri Sheinin, Paul L Crispen, Christopher J Krco and Eugene D Kwon
    Citation: Diagnostic Pathology 2010 5:48
    Content type: Research Published on:

  38. In order to provide reliable tissue material for malignant mesothelioma (MM) studies, we re-evaluated biopsies and autopsy material from 61 patients with a diagnosis of MM from the period of 1980-2002.

    Authors: Helmut P Sandeck, Oluf D Røe, Kristina Kjærheim, Helena Willén and Erik Larsson
    Citation: Diagnostic Pathology 2010 5:47
    Content type: Research Published on:

  40. Mammary tumors of female dogs have greatly increased in recent years, thus demanding rapid diagnosis and effective treatment in order to determine the animal survival. There is considerable scientific interest...

    Authors: Fábio HE Andrade, Fernanda C Figueiroa, Paulo RO Bersano, Denise Z Bissacot and Noeme S Rocha
    Citation: Diagnostic Pathology 2010 5:45
    Content type: Short report Published on:

  41. We report a rare case of primary lymphoma of fallopian tube in a 68-year-old woman who underwent total hysterectomy and bilateral salpingo-oophorectomy for endometrial carcinoma. The specimen showed a well-dif...

    Authors: Ahmad Alduaij, Katrine Hansen and Cunxian Zhang
    Citation: Diagnostic Pathology 2010 5:44
    Content type: Case Report Published on:

  42. Although mediastinal tumors compressing or invading the superior vena cava represent the major causes of the superior vena cava syndrome, benign processes may also be involved in the pathogenesis of this medic...

    Authors: Panagiotis Dedeilias, Ioannis Nenekidis, Panagiotis Hountis, Christos Prokakis, Paraskevi Dolou, Efstratios Apostolakis and Efstratios N Koletsis
    Citation: Diagnostic Pathology 2010 5:43
    Content type: Case Report Published on:

  43. A rare case of an apocrine tumor in the male perineal region is reported. A dermal cystic lesion developed in the region between the anus and scrotum of a 74-year-old Japanese male. The cystic lesion, measurin...

    Authors: Kazuhito Hatanaka, Akihide Tanimoto, Yoshihisa Umekita, Takako Yoshioka and Takuro Kanekura
    Citation: Diagnostic Pathology 2010 5:42
    Content type: Case Report Published on:

  44. Fascin induces membrane protrusions and cell motility. Fascin overexpression was associated with poor prognosis, and its downregulation reduces cell motility and invasiveness in esophageal squamous cell carcin...

    Authors: Cristian M Ortiz, Tetsuo Ito, Yosuke Hashimoto, Satoshi Nagayama, Akira Iwai, Shigeru Tsunoda, Fumiaki Sato, Miguel Martorell, Jose Angel Garcia, Ana Perez and Yutaka Shimada
    Citation: Diagnostic Pathology 2010 5:41
    Content type: Research Published on:

  46. Meningioangiomatosis is a rare hamartomatous lesion or meningiovascular malformation in brain. In extremely rare condition, meningioma may occur together with meningioangiomatosis, and only 19 cases have been ...

    Authors: Yan-yang Chen, Xiao-ying Tiang, Zhi Li, Bo-ning Luo and Quan Huang
    Citation: Diagnostic Pathology 2010 5:39
    Content type: Case Report Published on:

  48. This case describes an infiltrating breast tumour with thyroid transcription factor-1 (TTF-1) positive staining and ductal differentiation in a 72-year-old woman. The presence of ductal carcinoma in situ with ...

    Authors: Tor A Klingen, Ying Chen, Marian D Gundersen, Hans Aas, Bjørn Westre and Torill Sauer
    Citation: Diagnostic Pathology 2010 5:37
    Content type: Case Report Published on:

  49. Invasive lobular carcinomas (ILC) of breast typically demonstrate intracytoplasmic mucin. We present a unique case of classical type ILC with abundant extracellular mucin and strong ERBB2 (HER2/neu) expression co...

    Authors: Jing Yu, Rohit Bhargava and David J Dabbs
    Citation: Diagnostic Pathology 2010 5:36
    Content type: Case Report Published on:

  50. The aim of this study was to assess the relationship between expression of vascular endothelial growth factor (VEGF) and phosphatase and tensin homolog deleted in chromosome ten (PTEN), angiogenesis and clinic...

    Authors: Yurdanur Sullu, Seda Gun, Sinan Atmaca, Filiz Karagoz and Bedri Kandemir
    Citation: Diagnostic Pathology 2010 5:35
    Content type: Research Published on:
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