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  1. The virtual microscopy is widely accepted in Pathology for educational purposes and teleconsultation but is far from the routine use in surgical pathology due to the technical requirements and some limitations...

    Authors: Stephan Wienert, Michael Beil, Kai Saeger, Peter Hufnagl and Thomas Schrader
    Citation: Diagnostic Pathology 2009 4:3
    Content type: Software Published on:

  2. A 29-year-old woman presented with a breast tumor with a primary diagnosis of MALT lymphoma. A repeat biopsy revealed a hematological neoplasm with diffuse, Indian file, and targetoid patterns. The cells were ...

    Authors: Teresa A Vela-Chávez, Myrna D Arrecillas-Zamora, L Yolanda Quintero-Cuadra and Falko Fend
    Citation: Diagnostic Pathology 2009 4:2
    Content type: Case Report Published on:

  3. It has been more than 50 years since antinuclear antibodies were first discovered and found to be associated with connective tissue diseases. Since then different methods have been described and used for their...

    Authors: Yashwant Kumar, Alka Bhatia and Ranjana Walker Minz
    Citation: Diagnostic Pathology 2009 4:1
    Content type: Review Published on:

  4. Light emitting diodes (LED), which are available as small monochromatic light sources with characteristic features such as maximum illumination power combined with minimum energy consumption and extremely long...

    Authors: Dagmar S Lang, Tobias Zeiser, Holger Schultz, Florian Stellmacher, Ekkehard Vollmer, Peter Zabel and Torsten Goldmann
    Citation: Diagnostic Pathology 2008 3:49
    Content type: Short report Published on:

  6. Pilomatrix carcinoma is the rare malignant counterpart of pilomatrixoma, a skin adnexal tumour originating from hair matrix cells. Pilomatrix carcinoma can arise as a solitary lesion de novo, or through transform...

    Authors: Noel J Aherne, David A Fitzpatrick, David Gibbons and John G Armstrong
    Citation: Diagnostic Pathology 2008 3:47
    Content type: Case Report Published on:

  7. The chance of an intrathyroidal occurrence of a parathyroid gland is about 1–3%. Among the causes of hyperparathyroidism, parathyroid cases occur in less than 1% of patients. Here we present the case of a 63 y...

    Authors: Labiba Temmim, Fred Sinowatz, Wiam I Hussein, Osama Al-Sanea and Hady El-Khodary
    Citation: Diagnostic Pathology 2008 3:46
    Content type: Case Report Published on:

  8. Head and neck cancer including oral cancer is considered to develop by accumulated genetic alterations and the major pathway is cancerization from lesions such as intraepithelial dysplasia in oral leukoplakia ...

    Authors: Ali A Shamaa, Manal M Zyada, Mathias Wagner, Sally S Awad, Mohamed M Osman and Ali A Abdel Azeem
    Citation: Diagnostic Pathology 2008 3:45
    Content type: Research Published on:

  9. Renal epithelial tumors are morphologically, biologically, and clinically heterogeneous. Different morphologic subtypes require specific management due to markedly different prognosis and response to therapy. ...

    Authors: Jill M Hagenkord, Anil V Parwani, Maureen A Lyons-Weiler, Karla Alvarez, Robert Amato, Zoran Gatalica, Jose M Gonzalez-Berjon, Leif Peterson, Rajiv Dhir and Federico A Monzon
    Citation: Diagnostic Pathology 2008 3:44
    Content type: Research Published on:

  11. Male breast cancer is rare compared to its female counterpart representing less than 1% of cancer in men. Moreover, mucinous carcinoma of the male breast is an extremely rare histological subtype of malignancy...

    Authors: Dimitrios Peschos, Elena Tsanou, Pavlos Dallas, Konstantinos Charalabopoulos, Christos Kanaris and Anna Batistatou
    Citation: Diagnostic Pathology 2008 3:42
    Content type: Case Report Published on:

  12. Human epidermal growth factor receptor 2 (HER2) fluorescence in situ hybridization (FISH) is a quantitative assay for selecting breast cancer patients for trastuzumab therapy. However, current HER2 FISH procedure...

    Authors: Hiroaki Nitta, Beatrice Hauss-Wegrzyniak, Megan Lehrkamp, Adrian E Murillo, Fabien Gaire, Michael Farrell, Eric Walk, Frederique Penault-Llorca, Masafumi Kurosumi, Manfred Dietel, Lin Wang, Margaret Loftus, James Pettay, Raymond R Tubbs and Thomas M Grogan
    Citation: Diagnostic Pathology 2008 3:41
    Content type: Methodology Published on:

  14. The distinction between metastasis from a colorectal adenocarcinoma into the ovary and an ovarian adenocarcinoma is vital, but challenging at times, due to overlapping morphological features. Similarly, a dist...

    Authors: Bharat Rekhi, Sophia George, Bhulaxmi Madur, RF Chinoy, Rajesh Dikshit and Amita Maheshwari
    Citation: Diagnostic Pathology 2008 3:39
    Content type: Software Published on:

  16. The Seeplex™ TB Detection-2 assay (Rockville, MD) is a nested endpoint PCR for the Mycobacterium tuberculosis complex (MTBC) targets IS6110 and MPB64 that utilizes dual priming oligonucleotide technology. When us...

    Authors: Steven J Drews, AliReza Eshaghi, Daria Pyskir, Pam Chedore, Ernesto Lombos, George Broukhanski, Rachel Higgins, David N Fisman, Joanne Blair and Frances Jamieson
    Citation: Diagnostic Pathology 2008 3:37
    Content type: Short report Published on:

  17. We present the case of 80-year-old male with superficial papillary urothelial carcinoma of the urinary bladder with striking multicystic architecture with a combination of features of urothelial carcinoma with...

    Authors: Isabel Alvarado-Cabrero, Delia Pérez-Montiel and Ondrej Hes
    Citation: Diagnostic Pathology 2008 3:36
    Content type: Case Report Published on:

  18. In several tumors the transketolase activity, controlled inter alia by enzymes of the pentose phosphate pathway which is an alternative, energy generating reaction-cascade to glycolysis, has been correlated wi...

    Authors: Holger Schultz, Daniel Kähler, Detlev Branscheid, Ekkehard Vollmer, Peter Zabel and Torsten Goldmann
    Citation: Diagnostic Pathology 2008 3:35
    Content type: Short report Published on:

  20. Fibroadenomas are common benign breast tumours that display a characteristic pathological morphology, although several epithelial and stromal variations exist. A very rare histological finding is the presence ...

    Authors: Helen M Heneghan, Sean T Martin, Mary Casey, Igdam Tobbia, Fadel Benani and Kevin M Barry
    Citation: Diagnostic Pathology 2008 3:33
    Content type: Case Report Published on:

  21. Epithelial ovarian cancer is the fifth leading cause of cancer mortality among women in the United States. For this disease, differences in age-adjusted incidence and survival rates between African American an...

    Authors: Felix O Aikhionbare, Sharifeh Mehrabi, Winston Thompson, Xuebiao Yao, William Grizzle and Edward Partridge
    Citation: Diagnostic Pathology 2008 3:32
    Content type: Short report Published on:

  22. This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i....

    Authors: Wayne Grayson and Liron Pantanowitz
    Citation: Diagnostic Pathology 2008 3:31
    Content type: Review Published on:

  23. Tissue microarrays (TMAs) are used to study genomics and proteomics in several tumour tissue samples. Cell lines (CC) are of great importance in the study of the genetic changes in tumours, and some reveal sev...

    Authors: Rosa Noguera, Isidro Machado, Marta Piqueras, Jose Antonio Lopez-Guerrero, Samuel Navarro, Empar Mayordomo, Antonio Pellin and Antonio Llombart-Bosch
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S27
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  24. This study attempts to evaluate the GFAP and alpha1a-AR staining and morphometrical nuclear features of oligodendrogliomas and their prognostic implications as compared to present histopathology classification...

    Authors: Ernesto Moro-Rodríguez, Javier Figols, Mariano Alvira, José A Uranga-Ocio and Eduardo García-Poblete
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S26
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  25. Chondrosarcoma (Chs) is the third most frequent primary malignant tumour of bone and can be primary or secondary, the latter results mainly from the malignant transformation of a benign pre-existing tumour.

    Authors: Isidro Machado, Francisco Giner, Empar Mayordomo, Carmen Carda, Samuel Navarro and Antonio Llombart-Bosch
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S25
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  26. Education shows that active participation allows the best development of skills to acquire, and the results are better when the information is well documented. Now, with digital images and the Internet, in the...

    Authors: Hugo Góngora Jará and Héctor A Barcelo
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S24
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  27. Virtual slides are viewed using interactive software that enables the user to simulate the behaviour of a conventional optical microscope, like adjusting magnifications and navigating to any portion of the ima...

    Authors: Marcial García Rojo, Antonio J Gallardo, Lucía González, Carlos Peces, Cristina Murillo, Jesús González and Jose Sacristán
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S23
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  28. Process orientation is one of the essential elements of quality management systems, including those in use in healthcare. Business processes in hospitals are very complex and variable. BPMN (Business Process M...

    Authors: Marcial García Rojo, Elvira Rolón, Luis Calahorra, Felix Óscar García, Rosario Paloma Sánchez, Francisco Ruiz, Nieves Ballester, María Armenteros, Teresa Rodríguez and Rafael Martín Espartero
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S22
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  29. This research was conducted on ten glass slides selected from the histopathology evaluation chickens. Five slides of control's chickens healthy and five slides of chickens infected experimentally with chicken ...

    Authors: Luz García, Victor Bermudez, Mariela Brett, Luzmila Peroza, Juan Landa and Franklin Borregales
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S21
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  30. The present paper will present a survey on features of a number of non-specialized off-the-shelf JPEG2000 viewers, seen from the point of view of digital microscopy. Selected viewers were tested within a numbe...

    Authors: Vincenzo Della Mea, Nicola Bortolotti and Carlo Alberto Beltrami
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S20
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  31. Telepathology is becoming easier to implement in most pathology departments. In fact e-mail image transmit can be done from almost any pathologist as a simplistic telepathology system. We tried to develop a wa...

    Authors: Luis Alfaro and MaJosé Roca
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S19
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  32. This article presents a comparative study between different colour models (RGB, HSI and CIEL*a*b*) applied to a very large microscopic image analysis. Such analysis of different colour models is needed in orde...

    Authors: Gloria Bueno, Roberto González, Oscar Déniz, Jesús González and Marcial García-Rojo
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S18
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  33. Efficient use of whole slide imaging in pathology needs automated region of interest (ROI) retrieval and classification, through the use of image analysis and data sorting tools. One possible method for data s...

    Authors: Myriam Oger, Philippe Belhomme, Jacques Klossa, Jean-Jacques Michels and Abderrahim Elmoataz
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S17
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  34. Historically, histopathology evaluation is performed by a pathologist generating a qualitative assessment on thin tissue sections on glass slides. In the past decade, there has been a growing interest for tool...

    Authors: Coralie Apfeldorfer, Kristina Ulrich, Gareth Jones, David Goodwin, Susie Collins, Emanuel Schenck and Virgile Richard
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S16
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  35. To clarify the issues associated with the applications of virtual microscopy to the daily cytology slide screening, we conducted a survey at a slide conference of cytology. The survey was conducted specificall...

    Authors: Ichiro Mori, Osamu Nunobiki, Takashi Ozaki, Emiko Taniguchi and Kennichi Kakudo
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S15
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  36. Since their introduction in 1999, fully automated, high speed, high-resolution whole slide imaging devices have become increasing more reliable, fast and capable. While by no means perfect, these devices have ...

    Authors: John Gilbertson and Yukako Yagi
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S14
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  37. Virtual pathology is a very important tool that can be used in several ways, including interconsultations with specialists in many areas and for frozen sections. We considered in this work the use of Windows L...

    Authors: Clóvis Klock and Regina dePaulaXavier Gomes
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S13
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  38. This study examined the effect of tissue section thickness and consistency – parameters outside the direct control of the imaging devices themselves – on WSI capture speed and image quality. Preliminary data i...

    Authors: Yukako Yagi and John R Gilbertson
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S12
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  39. Automated image analysis, measurements of virtual slides, and open access electronic measurement user systems require standardized image quality assessment in tissue-based diagnosis.

    Authors: Klaus Kayser, Jürgen Görtler, Konradin Metze, Torsten Goldmann, Ekkehard Vollmer, Masoud Mireskandari, Zdravko Kosjerina and Gian Kayser
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S11
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  40. The Hypertext atlas of Dermatopathology, the Atlas of Fetal and Neonatal Pathology and Hypertext atlas of Pathology (this one in Czech only) are available at

    Authors: Josef Feit, Luděk Matyska, Vladimír Ulman, Lukáš Hejtmánek, Hana Jedličková, Marta Ježová, Mojmír Moulis and Věra Feitová
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S10
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  41. Hypertext atlas of fetal and neonatal pathology is a free resource for pregraduate students of medicine, pathologists and other health professionals dealing with prenatal medicine. The atlas can be found at

    Authors: Marta Ježová, Katarína Múčková, Ondřej Souček, Josef Feit and Pavel Vlašín
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S9
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  42. The application of Information and Communication Technologies (ICTs) in the field of university education can play an important role in order to fulfil the objectives of the European Space for Higher Education...

    Authors: José ErnestoMoro Rodríguez
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S8
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  43. The technological development of telemedicine has performed important progress, assuming a diagnostic relief role inside of the processes. Among the fields in fast evolution, telepathology is placed among thos...

    Authors: Roberto Mencarelli, Adriano Marcolongo and Alessio Gasparetto
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S7
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  44. We started to use virtual slide (VS) and virtual microscopy (VM) systems for quick frozen intra-operative telepathology diagnosis in Kyoto, Japan. In the system we used a digital slide scanner, VASSALO by CLAR...

    Authors: Yasunari Tsuchihashi, Terumasa Takamatsu, Yukimasa Hashimoto, Tooru Takashima, Kooji Nakano and Setsuya Fujita
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S6
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  45. Nowadays, there is no standard solution for acquiring, archiving and communication of Pathology digital images. In addition, there does not exist any commercial Pathology Information System (LIS) that can mana...

    Authors: Carlos Peces, Marcial García-Rojo, José Sacristán, Antonio José Gallardo and Ambrosio Rodríguez
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S5
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  46. Application of telemedicine systems to cover distant geographical areas has increased recently. However, the potential usefulness of similar systems for creation of national networks does not seem to be widely...

    Authors: Thomas Schrader and Ekaterina Kldiashvili
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S4
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  47. Telepathology recently entered a new era with the introduction of digital microscopes combined with Internet technology. The microscope allows viewing real time of whole slide (macro) as well as different chos...

    Authors: Lech Banach, Andrzej Stepien, Johann Schneider and Elizabeth Wichrzycka-Lancaster
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S3
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  48. Pathological examination includes gross & microscopic examinations at different magnification. Through the steps of examination, we obtain many images that can be used for telepathology. Telepathology is the p...

    Authors: Essam Ayad and Francesco Sicurello
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S2
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  49. In the last 10 years, whole slide imaging (WSI) has seen impressive progress not only in image quality and scanning speed but also in the variety of systems available to pathologists. However, we have noticed ...

    Authors: Yukako Yagi and John R Gilbertson
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S1
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

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Diagnostic Pathology

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