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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Extranodal NK/T cell lymphoma, nasal type (EN-NK/T-NT) is a rare and aggressive type of non-Hodgkin’s lymphoma. EN-NK/T-NT seldom occurs in the gastrointestinal tract, and renal involvement is relatively rare.

    Authors: Shuyan Mao, Changying Diao and Lei Cao
    Citation: Diagnostic Pathology 2022 17:75
    Content type: Case Report Published on:

  2. Lack of knowledge around underlying mechanisms of gliomas mandates intense research efforts to improve the disease outcomes. Identification of high-grade gliomas pathogenesis which is known for poor prognosis ...

    Authors: Reza Ahmadi-Beni, Shirin Shahbazi and Alireza Khoshnevisan
    Citation: Diagnostic Pathology 2022 17:73
    Content type: Research Published on:

  3. DICER1-associated central nervous system sarcoma (DCS) without evidence of other cancer-related syndromes is rare. Though the morphology of DCS was highly variable, the immunophenotype was predominant myogenic ph...

    Authors: Kun Yao, Zejun Duan, Jing Feng, Changxiang Yan and Xueling Qi
    Citation: Diagnostic Pathology 2022 17:72
    Content type: Case Report Published on:

  4. Hyperparathyroidism-Jaw Tumor (HPT-JT) is caused by inactivating germline mutations of CDC73. This hereditary disease can present with a range of symptoms. Jaw ossifying fibroma (OF) is one of the most importa...

    Authors: Dun Yang, Jiaoyun Zheng, Fei Tang, Qiongzhi He, Hui Huang and Peng Zhou
    Citation: Diagnostic Pathology 2022 17:71
    Content type: Case Report Published on:

  5. Immune checkpoints including programmed death-ligand 1/programmed death-1/ (PD-L1/PD-1), cytotoxic T lymphocyte antigen 4 (CTLA-4), and indolaimine-2, 3-deoxygenase (IDO) have recently emerged as effective can...

    Authors: Alireza Samiei, David W. Gjertson, Sanaz Memarzadeh, Gottfried E. Konecny and Neda A. Moatamed
    Citation: Diagnostic Pathology 2022 17:70
    Content type: Research Published on:

  7. The expression of PD-L1 in the immune microenvironment can guide the application of immunosuppressants. In order to monitor the immune status of the body, repeated biopsies have to be taken. Our research aims ...

    Authors: Keyu Yuan, Jiangping Wu, Yanjie Zhao, Shuzhen Lyu, Quan Zhou, Feng Shi, Yanping Li and Qingkun Song
    Citation: Diagnostic Pathology 2022 17:68
    Content type: Research Published on:

  9. This study retrospectively investigated the morphological, immunohistochemical and molecular genetic features of papillary renal neoplasm with reverse polarity (PRNRP), a recently described renal tumor.

    Authors: Tong Yang, Enhao Kang, Longxiao Zhang, Jie Zhuang, Yujun Li, Yanxia Jiang, Han Wang, Wenjuan Yu and Wei Zhang
    Citation: Diagnostic Pathology 2022 17:66
    Content type: Research Published on:

  12. Mu heavy chain disease is a rare lymphoid neoplasm characterized by vacuolated bone marrow plasma cells and secretion of defective mu immunoglobulin heavy chains. The biological basis of mu heavy chain disease...

    Authors: Vandana Baloda, Sarah E. Wheeler, David L. Murray, Mindy C. Kohlhagen, Jeffrey A. Vos, Svetlana A. Yatsenko, Mounzer E. Agha, Miroslav Djokic, Steven H. Swerdlow and Nathanael G. Bailey
    Citation: Diagnostic Pathology 2022 17:63
    Content type: Case Report Published on:

    The Correction to this article has been published in Diagnostic Pathology 2022 17:84

  13. We aimed to develop an artificial intelligence (AI)-assisted oral cytology method, similar to cervical cytology. We focused on the detection of cell nuclei because the ratio of cell nuclei to cytoplasm increas...

    Authors: Eiji Mitate, Kirin Inoue, Retsushi Sato, Youichi Shimomoto, Seigo Ohba, Kinuko Ogata, Tomoya Sakai, Jun Ohno, Ikuo Yamamoto and Izumi Asahina
    Citation: Diagnostic Pathology 2022 17:62
    Content type: Research Published on:

  14. Causative factors of breast cancer include infections, such as Epstein–Barr virus (EBV) infection. The aim of this study was to analyze the clinicopathological features of EBV-positive (IBC) and determine if E...

    Authors: Wei-tong Zhang, Gui-lu Zhu, Wu-qin Xu, Wei Zhang, Hui-zhen Wang, Ya-bing Wang and Yong-xiang Li
    Citation: Diagnostic Pathology 2022 17:61
    Content type: Research Published on:

  15. Contralateral neck lymph node metastasis is rare in primary breast cancer. Its clinical staging and treatment principles lack authoritative guidelines. A case of a 30-year-old breast cancer patient with contra...

    Authors: Xiaoxiao Zhong, Fengjiao Ding, Liyuan Qian, Wei Wu, Yanguang Wen and Boni Ding
    Citation: Diagnostic Pathology 2022 17:60
    Content type: Case Report Published on:

  16. Synovial sarcoma is an uncommon soft tissue tumor of soft tissue, characterized by a specific SS18 rearrangement. It generally manifests as a lesion composed of monomorphic spindle cells and sometimes shows va...

    Authors: Ying Chen, Ning Zhou, Deyu Guo, Xiaodong Wang, Xin He and Yujuan Xu
    Citation: Diagnostic Pathology 2022 17:59
    Content type: Case Report Published on:

  17. Plaque hardness in carotid artery stenosis correlates with cerebral infarction. This study aimed to quantitatively compare plaque hardness with histopathological findings and identify the pathological factors ...

    Authors: Daisuke Fukushima, Kosuke Kondo, Naoyuki Harada, Sayaka Terazono, Kei Uchino, Kazutoshi Shibuya and Nobuo Sugo
    Citation: Diagnostic Pathology 2022 17:58
    Content type: Research Published on:

  18. Vanishing bile duct syndrome (VBDS) is a rare but potentially severe acquired chronic cholestatic liver disease. Bile duct deficiency is a reduction of bile ducts in the liver, which can eventually lead to cho...

    Authors: Yuebo Jia, Lin Liu, Baocheng Deng, Yu Huang, Jiaqi Zhao and Guang Bai
    Citation: Diagnostic Pathology 2022 17:57
    Content type: Case Report Published on:

  19. The International System for Reporting Serous Fluid Cytopathology (TIS) was recently proposed. We retrospectively applied TIS recommendations for reporting the cytological diagnosis of serous effusions and rep...

    Authors: Yan-li Zhu, Wen-hao Ren, Qian Wang, Hai-zhu Jin, Yi-yi Guo and Dong-mei Lin
    Citation: Diagnostic Pathology 2022 17:56
    Content type: Research Published on:

  20. Rapid histologic diagnosis of frozen sections is essential for a variety of surgical procedures. Frozen sections however, require specialized lab equipment, are prone to freezing artifacts and are not applicab...

    Authors: Maja Carina Nackenhorst, Mohammad Kasiri, Bernd Gollackner and Heinz Regele
    Citation: Diagnostic Pathology 2022 17:55
    Content type: Research Published on:

  21. Former single center studies indicated that HER2 assessment with two primary tumor blocks (dual block HER2 assessment) could be an efficient and practical approach to overcome the adverse impact of heterogenei...

    Authors: Chen Xu, Miaomiao Sun, Mei Jin, Zengshan Li, Rong Qin, Guoping Ren, Wenyong Sun, Lirong Chen, Lijuan Luan, Yalan Liu, Dongxian Jiang, Lingli Chen, Rongkui Luo and Yingyong Hou
    Citation: Diagnostic Pathology 2022 17:54
    Content type: Research Published on:

  22. Primary intestinal T-cell lymphomas are uncommon malignancies that pose a diagnostic dilemma, because the clinical features and imaging findings commonly overlap with those encountered in inflammatory bowel di...

    Authors: Kashif Osmani, Eshana Shah, Bradley Drumheller, Shaun Webb, Manmeet Singh, Paul Rubinstein, John Patrick Galvin, Megan S. Lim and Carlos Murga-Zamalloa
    Citation: Diagnostic Pathology 2022 17:53
    Content type: Case Report Published on:

  23. Anaplastic lymphoma kinase rearrangement-associated renal cell carcinoma (ALK-RCC) is an extremely rare tumor and ALK-RCC that mimics mucinous tubular and spindle cell carcinoma (MTSCC) has been very reported ...

    Authors: Keita Kai, Shohei Tobu, Shinichi Kido, Shuji Mikami, Kengo Takeuchi, Akito Dobashi, Yuki Togashi, Mitsuru Noguchi and Shinichi Aishima
    Citation: Diagnostic Pathology 2022 17:52
    Content type: Case Report Published on:

  27. Malignant schwannoma is a malignant tumor of differentiation of Schwann cells or perineural cells.

    Authors: Imane Boujguenna, Hind Ousehal, Atmane Zaroual, Mohamed E. L. Bouderkaoui, Abdelaziz Raji, Chihab Bouyaali, Najat Cherif Idrissi El Ganouni, Anass Fakhri and Hanane Rais
    Citation: Diagnostic Pathology 2022 17:48
    Content type: Case Report Published on:

  28. We report a surgical case of urothelial carcinoma of the renal pelvis, resulting in diagnostic difficulties on cytological examination.

    Authors: Mao Takata, Motona Kumagai, Yumi Tsubata, Yoshiiku Okanemasa, Michiho Takenaka, Toshie Terauchi, Manabu Yamashita, Akihiro Shioya and Sohsuke Yamada
    Citation: Diagnostic Pathology 2022 17:47
    Content type: Case Report Published on:

  29. Neuroendocrine (NE) differentiation is widely studied in non-small cell lung carcinomas (NSCLC) however, its significance remains unclear in basaloid squamous cell carcinomas (B-SqCC). This study aims to asses...

    Authors: Kianoosh Keyhanian, William J. Phillips, Benjamin S. Yeung, Marcio Gomes, Bryan Lo and Harmanjatinder S. Sekhon
    Citation: Diagnostic Pathology 2022 17:46
    Content type: Research Published on:

  30. In breast cancer (BC) Ki-67 cut-off levels, counting methods and inter- and intraobserver variation are still unresolved. To reduce inter-laboratory differences, it has been proposed that cut-off levels for Ki...

    Authors: Anette H. Skjervold, Henrik Sahlin Pettersen, Marit Valla, Signe Opdahl and Anna M. Bofin
    Citation: Diagnostic Pathology 2022 17:45
    Content type: Research Published on:

  31. Ocular cystinosis is a rare autosomal recessive disorder characterized by intralysosomal cystine accumulation in renal, ophthalmic (cornea, conjunctiva), and other organ abnormalities. Patients with ocular cys...

    Authors: Latifa Chkioua, Yessine Amri, Chaima Saheli, Wassila Mili, Sameh Mabrouk, Imen Chabchoub, Hela Boudabous, Wissem Ben Azzouz, Hadhami Ben Turkia, Salima Ferchichi, Neji Tebib, Taieb Massoud, Mohamed Ghorbel and Sandrine Laradi
    Citation: Diagnostic Pathology 2022 17:44
    Content type: Research Published on:

  32. Authors: Yumiko Hori, Katsutoshi Hirose, Michio Ozeki, Kenji Hata, Daisuke Motooka, Shinichiro Tahara, Takahiro Matsui, Masaharu Kohara, Hiroki Higashihara, Yusuke Ono, Kaishu Tanaka, Satoru Toyosawa and Eiichi Morii
    Citation: Diagnostic Pathology 2022 17:43
    Content type: Correction Published on:

    The original article was published in Diagnostic Pathology 2022 17:19

  33. Extraskeletal myxoid chondrosarcomas (EMCs) are solid tumors that have been genetically and biologically characterized. Only a few studies have discussed the role of the KIT gene or CD117 expression in EMCs, iden...

    Authors: Chen Wang, Zhi-Jie You, Xiao-Yan Chen, Jie Lin and Yi-Juan Wu
    Citation: Diagnostic Pathology 2022 17:42
    Content type: Case Report Published on:

  34. Distinguishing benign lesion from early malignancy in melanocytic lesions of the nail unit still remains a diagnostic challenge, both clinically and histopathologically. While several immunohistochemistry (IHC...

    Authors: Young Jae Kim, Chang Jin Jung, Hyoungmin Na, Woo Jin Lee, Sung Eun Chang, Mi Woo Lee, Chan-Sik Park, Youngkyoung Lim and Chong Hyun Won
    Citation: Diagnostic Pathology 2022 17:41
    Content type: Research Published on:

  35. To explore whether the “WSI Stitcher”, a program we developed for reconstructing virtual large slide through whole slide imaging fragments stitching, can improve the efficiency and consistency of pathologists ...

    Authors: Dandan Han, Jun Liao, Meng Zhang, Chenchen Qin, Mengxue Han, Chun Wu, Jinze Li, Jianhua Yao and Yueping Liu
    Citation: Diagnostic Pathology 2022 17:40
    Content type: Research Published on:

  36. IFI16 plays an important role in innate immunity against invasive microbial infection by sensing double-stranded DNA viruses due to caspase-1-dependent inflammasome activation and subsequent maturation and sec...

    Authors: Li Liu, Shuangshuang Xie, Cheng Li, Yue Guo, Xiaoyan Liu, Xiuhua Zhao, Qiang Li and Wenjun Du
    Citation: Diagnostic Pathology 2022 17:39
    Content type: Research Published on:

  38. The occurrence of endocrine cell micronests in ovarian tumors is rarely reported. To our knowledge, there are only three prior cases reported to date: one occurring in an ovarian mucinous cystadenoma, one in a...

    Authors: Katrina Collins, Sheila Segura and Michael Hwang
    Citation: Diagnostic Pathology 2022 17:37
    Content type: Case Report Published on:

  39. The early detection of coronavirus disease (COVID-19) infection to improve disease management becomes the greatest challenge. Despite the high sensitivity of RT-PCR, not only it was reported that 20–67% of inf...

    Authors: Somaye Ghasemi, Narges Nazari Harmooshi and Fakher Rahim
    Citation: Diagnostic Pathology 2022 17:36
    Content type: Research Published on:

  41. Hemangioblastoma is an indolent mesenchymal tumor most frequently occurring in the central nervous system (CNS), but can also arise extraneuraxially, as part of Von Hippel-Lindau (VHL) disease or in sporadic t...

    Authors: Xintong Wang, George K. Haines III, Meenakshi Mehrotra, Jane Houldsworth and Qiusheng Si
    Citation: Diagnostic Pathology 2022 17:34
    Content type: Case Report Published on:

  42. Most of malignant melanomas originate from skin and often metastasize to the lungs, rarely metastasizes to the liver and bone. However, imageology characters of lung metastasis tumor are commonly similar to th...

    Authors: Juan Sun, Yun-Zhu Zhu, Pan-Pan Shao, Jing Ke, Wei Wang, Qiu-Lin Sun, Jia-Bin Li and Jun Cheng
    Citation: Diagnostic Pathology 2022 17:33
    Content type: Case Report Published on:

  43. To improve identification of patients with cutaneous squamous cell carcinoma (SCC) at high risk for metastatic disease, the DecisionDx-SCC assay, a prognostic 40-gene expression profile (40-GEP) test, was deve...

    Authors: Sherri Borman, Jeff Wilkinson, Lauren Meldi-Sholl, Clare Johnson, Kelsey Carter, Kyle R. Covington, Alison L. Fitzgerald, Sarah J. Kurley, Aaron S. Farberg, Matthew S. Goldberg, Federico A. Monzon, Kristen Oelschlager and Robert W. Cook
    Citation: Diagnostic Pathology 2022 17:32
    Content type: Research Published on:

  44. Despite a reported cardiac injury in patients with new coronavirus infection, the possibility and specifics of genuine viral myocarditis in COVID-19 remains not fully clear.

    Authors: Evgeniya Kogan, Yuriy Berezovskiy, Olga Blagova, Anna Kukleva, Lyudmila Semyonova, Evgeniy Gretsov and Atadzhan Ergeshov
    Citation: Diagnostic Pathology 2022 17:31
    Content type: Short report Published on:

  45. Pulmonary enteric adenocarcinoma (PEAC) has distinctive clinical outcomes, radiographic, pathological and molecular characteristics. The prognosis of patients with PEAC was poor. However, molecular profiles an...

    Authors: Min Xie, Dong Chen, Yong Li, Xiansheng Liu, Dong Kuang and Xiaochen Li
    Citation: Diagnostic Pathology 2022 17:30
    Content type: Research Published on:

  46. SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 4-deficient thoracic sarcoma (SMARCA4-DTS) is a rare disease that has recently been described as an entity. It is...

    Authors: Yusuke Kito, Keisuke Kawashima, Chiemi Saigo, Masayoshi Hasegawa, Shusuke Nomura, Takuya Mikamo, Yuki Hanamatsu, Yasuhiro Matsuo and Tamostu Takeuchi
    Citation: Diagnostic Pathology 2022 17:29
    Content type: Case Report Published on:

  47. The underlying mechanism of IgA vasculitis (IgAV) and IgA vasculitis with nephritis (IgAVN) remains unclear. Therefore, there are no accurate diagnostic methods. Lipid metabolism is related to many immune rela...

    Authors: Ying Liu, Min Wen, Qingnan He, Xiqiang Dang, Shipin Feng, Taohua Liu, Xuewei Ding, Xiaoyan Li and Xiaojie He
    Citation: Diagnostic Pathology 2022 17:28
    Content type: Research Published on:

  48. Anaplastic lymphoma kinase (ALK) gene rearrangements, have been identified in approximately 2-7% of patients with lung adenocarcinoma (LUAD). However, co-occurrence of double ALK fusions in one patient was rare. ...

    Authors: Hong Tao, Zhe Liu, Jing Mu, Fei Gai, Zhan Huang and Liang Shi
    Citation: Diagnostic Pathology 2022 17:27
    Content type: Case Report Published on:

  49. Large cell neuroendocrine carcinoma (LCNEC) is a high-grade malignant pulmonary neuroendocrine tumour. The distinction of pulmonary large cell carcinoma (LCC) and LCNEC is based on the presence of neuroendocri...

    Authors: Zuoyu Liang, Weiya Wang, Qianrong Hu, Ping Zhou, Ying Zhang, Yuan Tang, Qian Wu, Yiyun Fu, Xue Li, Yang Shao and Lili Jiang
    Citation: Diagnostic Pathology 2022 17:26
    Content type: Research Published on:

  50. Pulmonary carcinoid tumors rarely coexist with non-small cell lung carcinoma, and only nine cases have been reported previously. The pathogenesis and origin of these combined tumors remain unclear because of i...

    Authors: Chihiro Inoue, Sachiko Konosu-Fukaya, Kazuhiro Murakami, Ryoko Saito-Koyama, Hirofumi Watanabe, Hideki Mitomo, Naoya Ishibashi, Takafumi Sugawara, Toshiharu Tabata, Hironobu Sasano and Yasuhiro Nakamura
    Citation: Diagnostic Pathology 2022 17:25
    Content type: Case Report Published on:
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Diagnostic Pathology

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