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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Circular RNAs (circRNAs) have become a hot topic in the area of tumor biology due to its closed structure and the post-transcriptional regulatory effect. This study aims to clarify the roles of circRNA nuclear...

    Authors: Chuang Li, Lijuan Zhu, Lijun Fu, Mingli Han, Ya Li, Zhaozhong Meng and Xinguang Qiu
    Citation: Diagnostic Pathology 2021 16:93
    Content type: Research Published on:

  2. Fine-needle aspiration cytology (FNAC) is a basic diagnostic tool for thyroid nodules. However, 15–30% of nodules are cytologically indeterminate. Midkine (MK), a pleiotropic growth factor, is often upregulate...

    Authors: Le Zhou, Jinxi Jiang, Yantao Fu, Daqi Zhang, Tong Li, Qingfeng Fu, Chao Yan, Yifan Zhong, Gianlorenzo Dionigi, Nan Liang and Hui Sun
    Citation: Diagnostic Pathology 2021 16:92
    Content type: Research Published on:

  3. The rarity of juvenile psammomatoid ossifying fibroma (JPOF) and lack of cytogenetic studies prompted us to report a novel SETD2 gene mutation in a benign odontogenic tumour.

    Authors: A. Toferer, A. Truschnegg, K. Kashofer, C. Beham-Schmid and A. Beham
    Citation: Diagnostic Pathology 2021 16:91
    Content type: Case Report Published on:

  4. Acute fibrinous and organizing pneumonia (AFOP) is a rare histologic interstitial pneumonia pattern characterized by the intra-alveolar fibrin deposition and organizing pneumonia. Its clinical characteristics ...

    Authors: Haihong Chen, Yukun Kuang, Xinyan Huang, Ziyin Ye, Yangli Liu, Canmao Xie and Ke-Jing Tang
    Citation: Diagnostic Pathology 2021 16:90
    Content type: Case Report Published on:

  5. Secretory breast carcinoma is an uncommon subset of breast cancer that usually has a favorable outcome. Although initially described in children, it also occurs in adults where it may metastasize, possibly res...

    Authors: Jing Lian, Li-Xia Wang, Jiang-hong Guo, Peng Bu, Yan-feng Xi and Ke-ming Yun
    Citation: Diagnostic Pathology 2021 16:89
    Content type: Case Report Published on:

  6. COVID-19, the disease caused by the novel coronavirus SARS-CoV-2, is a severe systemic thrombotic syndrome that emerged in 2019, with an ensuing pandemic.

    Authors: Giovanna Giordano, Chiara Petrolini, Emilia Corradini, Nicoletta Campanini, Susanna Esposito and Serafina Perrone
    Citation: Diagnostic Pathology 2021 16:88
    Content type: Case Report Published on:

  8. Thyroid tumors are often difficult to histopathologically diagnose, particularly follicular adenoma (FA) and follicular carcinoma (FC). Papillary carcinoma (PAC) has several histological subtypes. Periostin (P...

    Authors: Kimihide Kusafuka, Masaru Yamashita, Tomohiro Iwasaki, Chinatsu Tsuchiya, Aki Kubota, Kazuki Hirata, Akinori Murakami, Aya Muramatsu, Kazumori Arai and Makoto Suzuki
    Citation: Diagnostic Pathology 2021 16:86
    Content type: Short report Published on:

  10. The incidence of papillary thyroid carcinoma (PTC) has been steadily increasing over the past decades. Hashimoto’s thyroiditis (HT) is the most common autoimmune disease, and is related to the pathogenesis of ...

    Authors: Chumeng Zhu, Yuechu Dai, Hui Zhang, Yanyun Ruan, Yong Zhou, Yingjie Dai, Lilong Fan, Tianjun Jia, Hongsheng Lu and Qi Chen
    Citation: Diagnostic Pathology 2021 16:84
    Content type: Research Published on:

  11. Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by hamartomas in multiple organs associated with germline mutations in TSC1 and TSC2, including exonic, intronic, or mosaic mutatio...

    Authors: Bogyeong Han, Juhwan Lee, Yoon Jin Kwak, Hyun-Young Kim, Kwang Hoon Lee, Yumi Shim, Hyunju Lee and Sung-Hye Park
    Citation: Diagnostic Pathology 2021 16:83
    Content type: Case Report Published on:

  12. A high incidence of malignant tumors, such as post-transplant lymphoproliferative disorders (PTLD), Kaposi sarcoma, and renal cancer is common in solid organ and bone marrow transplant recipients. However, mye...

    Authors: Danyang Wu, Xiaoxuan Lu, Xiaojing Yan and Ran Gao
    Citation: Diagnostic Pathology 2021 16:82
    Content type: Case Report Published on:

  13. Congenital hepatic fibrosis (CHF) is a rare inherited form of ductal plate malformation associated with polycystic kidney disease. The diagnosis requires histopathologic confirmation, but can be challenging to...

    Authors: Irene Y. Chen, Christa L. Whitney-Miller and Xiaoyan Liao
    Citation: Diagnostic Pathology 2021 16:81
    Content type: Research Published on:

  15. A definitive diagnosis of malignant peripheral nerve sheath tumor (MPNST) is challenging, especially in cases without neurofibromatosis 1 (NF1), because MPNST lacks specific markers on immunohistochemistry (IHC).

    Authors: Shintaro Sugita, Tomoyuki Aoyama, Makoto Emori, Tomomi Kido, Tomoko Takenami, Kodai Sakuraba, Kotomi Terai, Taro Sugawara, Mitsuhiro Tsujiwaki and Tadashi Hasegawa
    Citation: Diagnostic Pathology 2021 16:79
    Content type: Research Published on:

  17. Histopathological classification of Wilms tumors determines treatment regimen. Machine learning has been shown to contribute to histopathological classification in various malignancies but requires large numbe...

    Authors: Jikke J. Rutgers, Tessa Bánki, Ananda van der Kamp, Tomas J. Waterlander, Marijn A. Scheijde-Vermeulen, Marry M. van den Heuvel-Eibrink, Jeroen A. W. M. van der Laak, Marta Fiocco, Annelies M. C. Mavinkurve-Groothuis and Ronald R. de Krijger
    Citation: Diagnostic Pathology 2021 16:77
    Content type: Research Published on:

  18. First described in 1955 Primary mediastinal seminomas are rare. Only 1–4% of mediastinal tumours are germ cell tumors; majority of which are teratomas. They typically present in men aged between 20 and 40 year...

    Authors: Charlotte Holmes, Peh Sun Loo and Sion Barnard
    Citation: Diagnostic Pathology 2021 16:76
    Content type: Case Report Published on:

  19. There are recognised potential pitfalls in digital diagnosis in urological pathology, including the grading of dysplasia. The World Health Organisation/International Society of Urological Pathology (WHO/ISUP) ...

    Authors: Lisa Browning, Richard Colling and Clare Verrill
    Citation: Diagnostic Pathology 2021 16:75
    Content type: Short report Published on:

  20. With widespread clinical application of imaging techniques, renal space-occupying lesions have been identified at an increasing frequency. Here, we report two rare cases, Castleman disease (CD) and IgG4-relate...

    Authors: Bolong Liu, Yong Huang, Luying Tang, Jiexia Guan, Xiangfu Zhou and Hailun Zhan
    Citation: Diagnostic Pathology 2021 16:74
    Content type: Case Report Published on:

  21. Fusions of neurotrophic tropomyosin receptor kinase genes NTRK1, NTRK2 and NTRK3 with various partner genes occur in both common and rare tumours and are of paramount predictive value due to the availability of v...

    Authors: Florian Wagner, Ralf Greim, Kathrin Krebs, Finn Luebben and Arno Dimmler
    Citation: Diagnostic Pathology 2021 16:73
    Content type: Case Report Published on:

  22. Pancreaticobiliary maljunction (PBM) is a condition characterized by chronic inflammation due to refluxed pancreatic juice into the biliary tract that is associated with an elevated risk of biliary tract cance...

    Authors: Yasuhiro Kuraishi, Takeshi Uehara, Takashi Muraki, Mai Iwaya, Yasuhiro Kinugawa, Tomoyuki Nakajima, Takayuki Watanabe, Yusuke Miyagawa and Takeji Umemura
    Citation: Diagnostic Pathology 2021 16:72
    Content type: Research Published on:

  23. Histological images show strong variance (e.g. illumination, color, staining quality) due to differences in image acquisition, tissue processing, staining, etc. This can impede downstream image analysis such a...

    Authors: Marlen Runz, Daniel Rusche, Stefan Schmidt, Martin R. Weihrauch, Jürgen Hesser and Cleo-Aron Weis
    Citation: Diagnostic Pathology 2021 16:71
    Content type: Research Published on:

  24. Quick and reliable testing of EGFR and KRAS is needed in non-small cell lung cancer (NSCLC) to ensure optimal decision-making for targeted therapy. The Idylla™ platform was designed for Formalin-Fixed Paraffin-Em...

    Authors: Saskia Offerman, Clemens F. Prinsen, Ageeth Knol, Natalie Methorst, Jeanette Kamphorst and Maarten Niemantsverdriet
    Citation: Diagnostic Pathology 2021 16:70
    Content type: Short report Published on:

  26. Gastric-type endocervical adenocarcinoma is rare but the most common subtype of cervical adenocarcinoma not associated with human papillomavirus. It is more aggressive with a shorter five-year survival rate co...

    Authors: Anna Radomska, Daniel Lee, Heather Neufeld, Nancy Korte, Emina Torlakovic, Anita Agrawal and Rajni Chibbar
    Citation: Diagnostic Pathology 2021 16:68
    Content type: Research Published on:

  27. Sudden cardiac death (SCD) remains a great health threat and diagnostic challenge, especially those cases without positive autopsy findings. Molecular biomarkers have been urgently needed for the diagnosis of ...

    Authors: Fengping Yan, Yuanyuan Chen, Xing Ye, Fu Zhang, Shiquan Wang, Le Zhang and Xiaoting Luo
    Citation: Diagnostic Pathology 2021 16:67
    Content type: Research Published on:

  28. Certain gastric cancers exhibit some primitive phenotypes, which may indicate a high malignancy. In histologically differentiated early gastric cancer (EGC), the presence and the clinicopathological significan...

    Authors: Zhi-Yi Zhou, Jie Sun, Qing Guo, Hai-Bin Zhao and Zhi-Hua Zhou
    Citation: Diagnostic Pathology 2021 16:66
    Content type: Research Published on:

  29. Lipoprotein glomerulopathy (LPG) is a rare autosomal dominant disease caused by mutations in APOE, the gene which encodes apolipoprotein E. LPG mainly affects Asian individuals, however occasional cases have also...

    Authors: Joaquim Nelito da Silveira-Neto, Guilherme Jinson de Oliveira Ahn, Precil Diego Miranda de Menezes Neves, Vinicius Augusto Ferreira Baptista, Stanley de Almeida Araújo, David Campos Wanderley, Andréia Watanabe, Elieser Hitoshi Watanabe, Neide Missae Murai, Eny Maria Goloni Bertollo, Osvaldo Merege Vieira-Neto, Márcio Dantas, Sergio Ricardo de Antônio, Roberto Silva Costa, Maria Alice Sperto Ferreira Baptista, Miguel Moysés-Neto…
    Citation: Diagnostic Pathology 2021 16:65
    Content type: Case Report Published on:

  30. Diffuse malignant peritoneal mesothelioma (DMPM) is a rare malignant neoplasm with poor survival that shares some similarities with the best-known pleural variant, pleural mesothelioma. The recent European Ref...

    Authors: Federica Pezzuto, Luigi Vimercati, Francesco Fortarezza, Andrea Marzullo, Antonio Pennella, Domenica Cavone, Alessandra Punzi, Concetta Caporusso, Antonio d’Amati, Teresa Lettini and Gabriella Serio
    Citation: Diagnostic Pathology 2021 16:64
    Content type: Short report Published on:

  31. Dermatofibrosarcoma protuberans (DFSP) is a superficial fibroblastic tumor characterized by high rate of local recurrence and low metastatic potential. Fibrosarcomatous transformation can rarely arise in DFSP ...

    Authors: Yuan Chen, Ying-zhou Shi, Xiao-he Feng, Xiao-tong Wang, Xiang-lei He and Ming Zhao
    Citation: Diagnostic Pathology 2021 16:63
    Content type: Case Report Published on:

  32. The distribution of mucin phenotypes and their relationship with clinicopathological features in early differentiated gastric adenocarcinomas in a Chinese cohort are unknown. We aimed to investigate mucin phen...

    Authors: Kai Song, Qi Yang, Yu Yan, Xiaoyan Yu, Kanlun Xu and Jinghong Xu
    Citation: Diagnostic Pathology 2021 16:62
    Content type: Research Published on:

  33. Central mucoepidermoid carcinoma (MEC) is a rare salivary gland tumor that affects the jawbone. Glandular odontogenic cyst (GOC) is also a rare odontogenic developmental cyst with glandular differentiation. GO...

    Authors: Satoshi Maruyama, Taisuke Mori, Manabu Yamazaki, Tatsuya Abé, Eijitsu Ryo, Hiroyuki Kano, Go Hasegawa and Jun-ichi Tanuma
    Citation: Diagnostic Pathology 2021 16:61
    Content type: Case Report Published on:

  34. CCND1 copy number increase is characteristic of acral melanoma and is useful in distinguishing benign and malignant acral melanocytic lesions. Increase of the gene copy number may result in protein overexpression...

    Authors: Jianying Liu, Wenjuan Yu, Fei Gao, Shuangshuang Qi, Juan Du, Xiaolong Ma, Yan Zhang, Jie Zheng and Jing Su
    Citation: Diagnostic Pathology 2021 16:60
    Content type: Research Published on:

  35. Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is rare in Asians, and patients with CLL/SLL seldomly undergo kidney biopsy. The histopathological features and clinical relevance of tubuloint...

    Authors: Hui Wang, Xiaojuan Yu, Xu Zhang, Suxia Wang and Minghui Zhao
    Citation: Diagnostic Pathology 2021 16:59
    Content type: Research Published on:

  36. Ectopic adrenocortical tissue is a lesion usually found incidentally during autopsy or inguinal surgery. Here, we demonstrate an extremely unusual case of intrahepatic adrenocortical adenoma which highly mimic...

    Authors: Jingci Chen, Xueshuai Wan, Yao Lu, Wenze Wang, Dachun Zhao, Zhaohui Lu, Yilei Mao and Jie Chen
    Citation: Diagnostic Pathology 2021 16:58
    Content type: Case Report Published on:

  38. Secretory carcinoma of the breast is one of the rarest entities, accounting for less than 0.15 % of all infiltrating breast carcinomas. It has characteristic histopathological and molecular features and, in ge...

    Authors: Hongping Tang, Lihua Zhong, Hongbing Jiang, Yan Zhang, Guannan Liang, Guoyan Chen and Gui’e Xie
    Citation: Diagnostic Pathology 2021 16:56
    Content type: Case Report Published on:

  39. Undifferentiated embryonal sarcoma of liver (UESL) and hepatic mesenchymal hamartoma (HMH) are two rare entities which mainly affect the pediatric population. The aim of this investigation was to provide a com...

    Authors: Parham Habibzadeh, Mohaddese Ansari Asl, Hamid Reza Foroutan, Ali Bahador and Mohammad Hossein Anbardar
    Citation: Diagnostic Pathology 2021 16:55
    Content type: Research Published on:

  40. The novel SS18-SSX fusion-specific antibody is reported to have high sensitivity and specificity for the diagnosis of primary synovial sarcoma (SS), which often metastasizes to the lung. Thus far, no study has...

    Authors: Kentaro Miura, Kimihiro Shimizu, Takashi Eguchi, Sachie Koike, Shunichiro Matsuoka, Tetsu Takeda, Kazutoshi Hamanaka and Takeshi Uehara
    Citation: Diagnostic Pathology 2021 16:54
    Content type: Research Published on:

  41. Malignancy after transplantation is a leading cause of death among kidney transplant recipients. However, donor-derived malignancies are rare. We report a case of a high grade papillary urothelial carcinoma ar...

    Authors: Joyce M. Chen, G. Kenneth Haines III, William Lam, Asha Reddy, Meenakshi Mehrotra, Jane Houldsworth and Qiusheng Si
    Citation: Diagnostic Pathology 2021 16:53
    Content type: Case Report Published on:

  42. Undifferentiated carcinoma of the biliary tract are highly aggressive malignancies. In other organs, a subgroup of undifferentiated carcinoma related to SWI/SNF complex–deficiency have been described.

    Authors: Tiemo S. Gerber, Abbas Agaimy, Arndt Hartmann, Michael Habekost, Wilfried Roth, Albrecht Stenzinger, Peter Schirmacher and Beate K. Straub
    Citation: Diagnostic Pathology 2021 16:52
    Content type: Case Report Published on:

  43. As a new type of molecular marker, microRNAs (miRNAs) can be used for early diagnosis and prognosis prediction of malignant tumors, and has broad clinical application prospects. This paper mainly studies the i...

    Authors: He Wang, Huiwen Wang, Wenyu Cui, Qiao Zhang, Jing Li and Qi Zhang
    Citation: Diagnostic Pathology 2021 16:51
    Content type: Research Published on:

  44. BCOR-CCNB3 sarcoma (BCS) is a group of undifferentiated small round cell sarcomas harboring the BCOR gene rearrangement which shares morphology with the Ewing sarcoma family as well as other malignant round blue ...

    Authors: Lan Li, Ming Zhang, Shaoyu Chen, Xiaoqi Sun, Hairong Xu, Lina Li, Tingting Zhang, Xiaoyuan Huang, Hongtao Ye and Yi Ding
    Citation: Diagnostic Pathology 2021 16:50
    Content type: Research Published on:

  45. Esophageal granular cell tumor (eGCT) is rare, and the recent literature suggests a link between eosinophilic esophagitis (EoE) and eGCT. The aim of our study was to determine if EoE or other disorders associa...

    Authors: Deepti Reddi, Christropher Chandler, Diana Cardona, Michael Schild, Maria Westerhoff, Emily McMullen, Yutaka Tomizawa, Lani Clinton and Paul E. Swanson
    Citation: Diagnostic Pathology 2021 16:49
    Content type: Research Published on:

  46. Systemic Epstein-Barr virus+ T-cell lymphoma (sEBV+ TCL) occurs in childhood and young adults, and is exceptionally rare in older adults.

    Authors: Ziyao Wang, Shoichi Kimura, Hiromi Iwasaki, Ken Takase, Yumi Oshiro, Ayako Gamachi, Kosuke Makihara, Masao Ogata, Tsutomu Daa, Seiya Momosaki, Yasushi Takamatsu and Morishige Takeshita
    Citation: Diagnostic Pathology 2021 16:48
    Content type: Research Published on:

  47. Colorectal cancer (CRC) is one of the third normal malignancy worldwide. Taurine-upregulated gene 1 (TUG1), a member of long noncoding RNAs (lncRNAs), has been reported to be involved in various cancers. Howev...

    Authors: Quanlin Liu, Wei Zhang, Linshan Luo, Keshun Han, Ruitao Liu, Shue Wei and Xiaoran Guo
    Citation: Diagnostic Pathology 2021 16:47
    Content type: Research Published on:

  48. Long non-coding RNA growth arrest specific 5 (GAS5) is a regulator in non-small cell lung cancer (NSCLC) progression. Nonetheless, the mechanism by which GAS5 exerts its biological function in NSCLC cells rema...

    Authors: Juan Ma, Haiyan Miao, Haiyun Zhang, Jingjing Ren, Shengyan Qu, Jing Da, Feifan Xu and Huan Zhao
    Citation: Diagnostic Pathology 2021 16:46
    Content type: Research Published on:

  49. Triple-negative breast cancer (TNBC) is a special type of breast cancer that lacks effective therapeutic targets. There is a significant need to clarify its pathogenesis, so as to bring new targeted approaches...

    Authors: Jie Sun, Xiaohua Li, Enqiao Yu, Jianxia Liu, Liang Sun, Qin He and Qiran Lu
    Citation: Diagnostic Pathology 2021 16:45
    Content type: Research Published on:
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Diagnostic Pathology

ISSN: 1746-1596

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