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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Primary pulmonary myxoid sarcoma (PPMS) is an extremely rare lung sarcoma that is characterized in most cases by recurrent balanced chromosomal translocation t(2;22)(q33;q12) leading to the oncogenic fusion gene

    Authors: Zhenwei Chen, Yihui Yang, Rongming Chen, Chi Sing Ng and Hongqi Shi
    Citation: Diagnostic Pathology 2020 15:15
    Content type: Case Report Published on:

  2. To investigate the role of FOXM1, β-catenin and TCF4 in esophageal cancer (EC) and their relationship to VM (Vasculogenic Mimicry).

    Authors: Lili Cheng, Qi Wang, Xiaoying Tao, Yanzi Qin, Qiong Wu, Dafang Zheng, Damin Chai, Yong Zhang, Dongbing Lu, Hongfei Ci, Zhiwei Wang, Jia Ma, Danna Wang, Zenong Cheng, Shiwu Wu and Yisheng Tao
    Citation: Diagnostic Pathology 2020 15:14
    Content type: Research Published on:

  3. Primary thyroid Burkitt’s lymphoma (BL) is an extremely rare and highly aggressive form of non-Hodgkin’s lymphoma; only isolated case reports are available for patients with this disease.

    Authors: Toshitetsu Hayashi, Mitsuyoshi Hirokawa, Seiji Kuma, Miyoko Higuchi, Ayana Suzuki, Risa Kanematsu, Takumi Kudo, Naomi Katsuki, Reiji Haba and Akira Miyauchi
    Citation: Diagnostic Pathology 2020 15:13
    Content type: Case Report Published on:

  4. Squamous cell carcinoma is the most common malignant tumor of the uterine cervix with a well-documented link to infection with human papillomaviruses (HPV). According to a recent classification, there are seve...

    Authors: Jan Hrudka, Blanka Rosová and Michael J. Halaška
    Citation: Diagnostic Pathology 2020 15:12
    Content type: Case Report Published on:

  5. Primary malignant melanoma of the lung (PML) is extremely rare. No precursor lesions of PML have been identified, and little is known about the genetic mutations associated with the disease. Typically, 15–20% ...

    Authors: Takashi Hibiya, Meiro Tanaka, Mai Matsumura, Ayako Aoki, Tadashi Ikegami, Koji Okudela, Naomi Kawano and Kenichi Ohashi
    Citation: Diagnostic Pathology 2020 15:11
    Content type: Case Report Published on:

  6. CD68+ tumor-associated macrophages (TAM) play an important role in the progression of classical Hodgkin lymphoma (cHL). We assessed the role of CD20 and CD68 + TAM in a cohort of cHL patients from Egypt and corre...

    Authors: Osama Mohamed, Ahmed El Bastawisy, Nasr Allahlobi, Mona S. Abdellateif, Abdel Rahman N. Zekri, Sabry Shaarawy, Zeinab Korany, Marwa Mohanad and Abeer A. Bahnassy
    Citation: Diagnostic Pathology 2020 15:10
    Content type: Research Published on:

  7. Non-surgical cytological specimens are adequate not only for accurate histological subtyping but also for molecular profiling. A modified amplification refractory mutation system polymerase chain reaction (ARM...

    Authors: Wei Wu, Ziyang Cao, Wei Zhang, Liping Zhang, Likun Hou and Chunyan Wu
    Citation: Diagnostic Pathology 2020 15:9
    Content type: Research Published on:

  8. Gastrointestinal stromal tumors (GISTs) are the most common type of adult mesenchymal neoplasms. The events that drive GIST oncogenesis are primarily KIT or PDGFRA mutations, which lead to the susceptibility of t...

    Authors: Jun Fan, Ming Yang, Bo Huang, Zhenkao Wang, Danju Luo, Jiwei Zhang, Peng Zhang, Heshui Shi, Yan Li and Xiu Nie
    Citation: Diagnostic Pathology 2020 15:8
    Content type: Case Report Published on:

  9. Cutaneous pilomatrical carcinosarcoma (CS) is a very rare biphasic tumor composed of admixed epithelial and mesenchymal malignant cells, with limited information on its pathogenesis. We report a case of piloma...

    Authors: Thi My Hanh Luong, Yuko Akazawa, Zhanna Mussazhanova, Katsuya Matsuda, Nozomi Ueki, Shiro Miura, Toshihide Hara, Hiroko Yokoyama and Masahiro Nakashima
    Citation: Diagnostic Pathology 2020 15:7
    Content type: Case Report Published on:

  10. To achieve optimal outcomes, an individual approach is needed in the treatment and care of patients. The potential value of tumor mutational burden (TMB) status and/or programmed cell death ligand 1 (PD-L1) ex...

    Authors: Tina Krieger, Isobel Pearson, Judith Bell, Jim Doherty and Paul Robbins
    Citation: Diagnostic Pathology 2020 15:6
    Content type: Review Published on:

  11. Precision medicine based on genomic analysis of germline or tumor tissue is attracting attention. However, there is no consensus on how to apply the results of genomic analysis to treatment.

    Authors: Hiroshi Hongo, Takeo Kosaka, Eriko Aimono, Hiroshi Nishihara and Mototsugu Oya
    Citation: Diagnostic Pathology 2020 15:5
    Content type: Case Report Published on:

  12. An intravenous leiomyomatosis is a special type of uterine leiomyoma characterized by the formation of benign leiomyomatous tissue within the vascular wall. Although histologically benign, intracardiac metasta...

    Authors: Mitsutake Yano, Tomomi Katoh, Yoshie Nakajima, Shiro Iwanaga, Rei Kin, Eito Kozawa and Masanori Yasuda
    Citation: Diagnostic Pathology 2020 15:4
    Content type: Case Report Published on:

  14. NUT midline carcinoma (NMC) is a poorly differentiated squamous cancer with a median survival at less than 7 months. NMC is resistant to conventional chemotherapies and characterized by rearrangement of the NUT g...

    Authors: Peiwei Chai, Chuandi Zhou, Renbing Jia and Yefei Wang
    Citation: Diagnostic Pathology 2020 15:2
    Content type: Case Report Published on:

  15. FNA is a simple, safe, cost-effective and accurate diagnostic tool for the initial screening of patients with thyroid nodules. The aims of this study were to determine the diagnostic utility of FNAC performed ...

    Authors: Yanli Zhu, Yuntao Song, Guohui Xu, Zhihui Fan and Wenhao Ren
    Citation: Diagnostic Pathology 2020 15:1
    Content type: Research Published on:

  17. Epithelioid rhabdomyosarcoma is a rare tumor that generally occurs in the bladder, the parotid gland, or the skin of the neck. We describe an unusual case of primary epithelioid rhabdomyosarcoma of the stomach...

    Authors: Yangkun Wang, Pei Guo, Zhishang Zhang, Runde Jiang and Zuguo Li
    Citation: Diagnostic Pathology 2019 14:137
    Content type: Case Report Published on:

  19. Splenic cord capillary hemangioma is a rare benign vascular lesion classified as a splenic hamartoma. On the other hand, non-islet cell tumor hypoglycemia (NICTH) is one of the rare causes of spontaneous hypog...

    Authors: Tatsuaki Daimon, Takeo Kosaka, Minoru Horinaga, Junichi Saito, Yoshito Ueyama, Shoji Matsuzaki and Mototsugu Oya
    Citation: Diagnostic Pathology 2019 14:135
    Content type: Case Report Published on:

  20. Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known. Here, we have investigated the f...

    Authors: Caroline E. Nunes-Xavier, Olaia Aurtenetxe, Laura Zaldumbide, Ricardo López-Almaraz, Asier Erramuzpe, Jesús M. Cortés, José I. López and Rafael Pulido
    Citation: Diagnostic Pathology 2019 14:134
    Content type: Research Published on:

  21. Interpretation of mediastinal biopsy is often challenging even for experienced pathologists especially when a hematolymphoid neoplasm is suspected. Primary mediastinal large B-cell lymphoma (PMLBCL) and classi...

    Authors: Hyun-Jung Kim, Hee Kyung Kim, Gyeongsin Park, Soo Kee Min, Hee Jeong Cha, Hyekyung Lee, Suk Jin Choi, Hee Young Na, Ji-Young Choe and Ji Eun Kim
    Citation: Diagnostic Pathology 2019 14:133
    Content type: Research Published on:

  22. MicroRNAs (miRNAs) have been reported to serve pivotal roles in tumorigenesis. This study sough to assess the expression and clinical significance of microRNA-1298 (miR-1298) in patients with non-small cell lu...

    Authors: Zhonghai Du, Jun Wu, Juan Wang, Yan Liang, Sensen Zhang, Zhimei Shang and Wenchao Zuo
    Citation: Diagnostic Pathology 2019 14:132
    Content type: Research Published on:

  23. Increasing evidence indicates the utility of transbronchial lung cryobiopsy (TBLC) for the diagnosis of interstitial lung disease (ILD). However, only one study has compared TBLC and surgical lung biopsy (SLB)...

    Authors: Yoshiaki Zaizen, Yasuo Kohashi, Kishio Kuroda, Kazuhiro Tabata, Yuka Kitamura, Akira Hebisawa, Yuji Saito and Junya Fukuoka
    Citation: Diagnostic Pathology 2019 14:131
    Content type: Research Published on:

  24. Distant metastases from follicular thyroid carcinoma are mainly hematogenous and are commonly observed in the lungs and bones. Other rare sites are the parotid gland, skin, brain, ovary, adrenal gland, kidney,...

    Authors: Taolang Li, Zhiyuan Ma, Chengli Lu, Quanzhong Zhou, Zelong Feng, Xinglong Wu, Yi Luo, Dan Li, Xiaoming Cheng and Xuemei Liu
    Citation: Diagnostic Pathology 2019 14:130
    Content type: Case Report Published on:

  26. Large B cell lymphoma (DLBCL) is the most common type of non-Hodgkin’s lymphoma among adults. In some cases, DLBCL may seem similar to carcinoma cells, presenting a round, oval, or polygonal shape and clear nu...

    Authors: Wan-Ming Hu, Jie-Tian Jin, Chen-Yan Wu, Jia-Bin Lu, Li-Hong Zhang, Jing Zeng and Su-Xia Lin
    Citation: Diagnostic Pathology 2019 14:128
    Content type: Research Published on:

  27. Follicular thyroid carcinoma (FTC) is a neoplasm that presents with a micro-follicular growth pattern and a neutrally stained cytoplasm. Seldom, FTCs display unusual morphological characteristics – but given t...

    Authors: Martin Hysek, Kenbugul Jatta, Adam Stenman, Eva Darai-Ramqvist, Jan Zedenius, Anders Höög and C. Christofer Juhlin
    Citation: Diagnostic Pathology 2019 14:127
    Content type: Case Report Published on:

  28. Myeloid sarcoma (MS), which represents a rare malignancy that comprises of myeloid blasts occurring at extra-medullary sites, closely correlates with the onset and relapse of acute myeloid leukemia (AML) and o...

    Authors: Xilin Zhang, Peichen Huang, Zhuo Chen, Xinling Bi, Ying Wang and Jianhua Wu
    Citation: Diagnostic Pathology 2019 14:126
    Content type: Case Report Published on:

  29. Vulvar extramammary Paget disease is a rare chronic condition, that presents with non-specific symptoms such as pruritus and eczematous lesions. Because most of these lesions are noninvasive, the distinction b...

    Authors: Walquiria Quida Salles Pereira Primo, Guttenberg Rodrigues Pereira Primo, Dunya Bachour Basilio, Karime Kalil Machado, Jesus Paula Carvalho and Filomena M. Carvalho
    Citation: Diagnostic Pathology 2019 14:125
    Content type: Case Report Published on:

  30. In spite of the multimodal treatment used today, glioblastoma is still the most aggressive and lethal cerebral tumour. To increase survival in these patients, novel therapeutic targets must be discovered. Sign...

    Authors: Sergiu Susman, Radu Pîrlog, Daniel Leucuța, Andrei Otto Mitre, Vlad Adrian Padurean, Carmen Melincovici, Ioana Moldovan, Doinița Crișan and Stefan Ioan Florian
    Citation: Diagnostic Pathology 2019 14:124
    Content type: Research Published on:

  31. Hyperphosphatasia with mental retardation syndrome (HPMRS) is a recessive disorder characterized by high blood levels of alkaline phosphatase together with typical dysmorphic signs such as cleft palate, intell...

    Authors: Layal Abi Farraj, Wassim Daoud Khatoun, Naji Abou Chebel, Victor Wakim, Katia Dawali and Michella Ghassibe-Sabbagh
    Citation: Diagnostic Pathology 2019 14:123
    Content type: Case Report Published on:

  32. Teratocarcinosarcoma (TCS) is a rare aggressive tumor of the nasal cavity and paranasal sinuses and has both epithelial and two or more mesenchymal components. In other organs, 5 cases of ovarian tumors closel...

    Authors: Kozue Ito, Mitsutake Yano, Aiko Ogasawara, Maiko Miwa, Eito Kozawa and Masanori Yasuda
    Citation: Diagnostic Pathology 2019 14:122
    Content type: Case Report Published on:

  34. Protein arginine methyltransferase-1 (PRMT1) is associated with the progression of various tumor types and the process of epithelial to mesenchymal transition (EMT). However, the expression of PRMT1 in renal c...

    Authors: Jelena Filipović, Martina Bosić, Sanja Ćirović, Maja Životić, Duško Dunđerović, Dejan Đorđević, Snežana Živković-Perišić, Aleksandar Lipkovski and Jasmina Marković-Lipkovski
    Citation: Diagnostic Pathology 2019 14:120
    Content type: Research Published on:

  35. Gestational diabetes mellitus (GDM) leads to poor pregnancy outcomes. Strategies that improve trophoblast cell function are important methods for GDM treatment. This study aimed to investigate the expression a...

    Authors: Xuegui Zhou, Cuiping Xiang and Xiaoxia Zheng
    Citation: Diagnostic Pathology 2019 14:119
    Content type: Research Published on:

  36. Carboxypeptidase X, M14 family member 2 (CPXM2), has been associated with several human developmental disorders. However, whether CPXM2 is involved in oncogenesis or tumor progression remains unclear. Currentl...

    Authors: Xin Zhao, Ronghang Li, Qian Wang, Minfei Wu and Yanbing Wang
    Citation: Diagnostic Pathology 2019 14:118
    Content type: Research Published on:

  38. Gastrointestinal stromal tumors (GISTs), a type of mesenchymal tumor in the gastrointestinal tract, are believed to be closely associated with PDGFRA and C-KIT mutations. Schwannoma in the stomach, which is an...

    Authors: Yuxin Li, Yongliang Teng, Xiaofei Wei, Zhuang Tian, Yuqing Cao, Xiaona Liu and Xiumei Duan
    Citation: Diagnostic Pathology 2019 14:116
    Content type: Case Report Published on:

  39. Primary cutaneous CD30+ lymphoproliferative disorders (pc-CD30-LPD) are a group of clonal T cell lymphoproliferative disorders that despite very similar tumor histology follow different and characteristic clin...

    Authors: Cristiane Rúbia Ferreira, Shuchun Zhao, José Antonio Sanches, Denis Miyashiro, Jade Cury-Martins, Raymundo Soares Azevedo, Maria C. N. Zerbini, Yasodha Natkunam and Dita Gratzinger
    Citation: Diagnostic Pathology 2019 14:115
    Content type: Research Published on:

  40. Recent studies have shown that T cell-mediated cellular immune mechanisms play important roles in the progression of hepatitis B to liver cirrhosis, but the underlying mechanisms remain unclear. This present s...

    Authors: Yong-Ting Lan, Zhen-li Wang, Peng Tian, Xiao-Na Gong, Yu-Chen Fan and Kai Wang
    Citation: Diagnostic Pathology 2019 14:114
    Content type: Research Published on:

  41. Rapid (“warm”) autopsies of patients with advanced metastatic cancer provide important insight into the natural history, pathobiology and histomorphology of disease in treatment-resistant tumors. Plasmacytoid ...

    Authors: Caroline T. Simon, Stephanie L. Skala, Paul D. Killen, Javed Siddiqui, Xuhong Cao, Yuanyuan Qiao, Hikmat Al-Ahmadie, Sandra I. Camelo-Piragua, Jeffrey Jentzen, Arul M. Chinnaiyan, Saravana M. Dhanasekaran, Zachery R. Reichert and Rohit Mehra
    Citation: Diagnostic Pathology 2019 14:113
    Content type: Case Report Published on:

  42. Translocation-associated renal cell carcinoma involving ALK (ALK-tRCC) is a rare subtype of adult renal cell carcinoma (RCC) reported in recent years. It was recognized as a group of emerging /provisional RCC ...

    Authors: Jing Yang, Lei Dong, Hong Du, Xiu-bo Li, Yan-xiao Liang and Guo-rong Liu
    Citation: Diagnostic Pathology 2019 14:112
    Content type: Case Report Published on:

  43. Epithelioid sarcoma (ES) is a rare malignant soft tissue tumor, commonly occurring in distal extremities, such as fingers, hands and wrists. For oncologists and surgeons, a female patient with enlarged axillar...

    Authors: Luyan Chen, Li Wang, Xiaochen Zhang, Minya Yao and Peifen Fu
    Citation: Diagnostic Pathology 2019 14:111
    Content type: Case Report Published on:

  44. Low-grade endometrial stromal sarcoma (ESS) is rare mesenchymal neoplasm, recently specified as harboring JAZF1–SUZ12 rearrangement. Typical JAZF1–SUZ12 ESS is slow growing, in which high uptake of fluorodeoxyglu...

    Authors: Koto Fujiishi, Shigenori Nagata, Rieko Kano, Chiaki Kubo, Maasa Shirayanagi, Megumi Ozaki, Takashi Yamamoto, Katsuyuki Nakanishi, Shoji Kamiura and Shin-ichi Nakatsuka
    Citation: Diagnostic Pathology 2019 14:110
    Content type: Case Report Published on:

  45. Laryngeal squamous cell carcinoma (LSCC) is considered to be a common malignancy of the head and neck with poor prognosis for its late diagnosis, metastasis and recurrence. Growing evidence demonstrates that t...

    Authors: Ruihua Fang, Yongjin Huang, Jinghua Xie, Jianzhong Zhang and Xiaobin Ji
    Citation: Diagnostic Pathology 2019 14:109
    Content type: Research Published on:

  46. Mcl-1, an anti-apoptotic member of bcl-2 family, together with cleaved poly (ADC-ribose) polymerase (c-PARP) can serve as a marker of cell apoptosis. Previously we reported that treatment of Mnk inhibitor CGP5...

    Authors: Qiuyuan Wen, Yuting Zhan, Hongmei Zheng, Hongjing Zang, Jiadi Luo, Yuting Zhang, Weiyuan Wang, Juan Feng, Junmi Lu, Lingjiao Chen and Songqing Fan
    Citation: Diagnostic Pathology 2019 14:108
    Content type: Research Published on:

  49. High ERCC1 expression is thought to be related with resistance to chemotherapy based on platinum. The aim of this study was to present our institutional observations regarding to the association of ERCC1 and o...

    Authors: Marina Piljić Burazer, Suzana Mladinov, Antonela Matana, Sendi Kuret, Joško Bezić and Merica Glavina Durdov
    Citation: Diagnostic Pathology 2019 14:105
    Content type: Research Published on:

  50. The category of grade 3 neuroendocrine tumor (NET G3) was newly introduced in the 2017 World Health Organization (WHO 2017) classification of neuroendocrine neoplasms of the pancreas. Pancreatic NET G3 shows a...

    Authors: Kenji Inafuku, Tomoyuki Yokose, Hiroyuki Ito, Daisuke Eriguchi, Joji Samejima, Takuya Nagashima, Haruhiko Nakayama, Masaki Suzuki, Kouzo Yamada and Munetaka Masuda
    Citation: Diagnostic Pathology 2019 14:104
    Content type: Case Report Published on:
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Diagnostic Pathology

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