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  1. Tissue microarrays (TMAs) are used to study genomics and proteomics in several tumour tissue samples. Cell lines (CC) are of great importance in the study of the genetic changes in tumours, and some reveal sev...

    Authors: Rosa Noguera, Isidro Machado, Marta Piqueras, Jose Antonio Lopez-Guerrero, Samuel Navarro, Empar Mayordomo, Antonio Pellin and Antonio Llombart-Bosch
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S27
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  2. This study attempts to evaluate the GFAP and alpha1a-AR staining and morphometrical nuclear features of oligodendrogliomas and their prognostic implications as compared to present histopathology classification...

    Authors: Ernesto Moro-Rodríguez, Javier Figols, Mariano Alvira, José A Uranga-Ocio and Eduardo García-Poblete
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S26
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  3. Chondrosarcoma (Chs) is the third most frequent primary malignant tumour of bone and can be primary or secondary, the latter results mainly from the malignant transformation of a benign pre-existing tumour.

    Authors: Isidro Machado, Francisco Giner, Empar Mayordomo, Carmen Carda, Samuel Navarro and Antonio Llombart-Bosch
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S25
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  4. Education shows that active participation allows the best development of skills to acquire, and the results are better when the information is well documented. Now, with digital images and the Internet, in the...

    Authors: Hugo Góngora Jará and Héctor A Barcelo
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S24
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  5. Virtual slides are viewed using interactive software that enables the user to simulate the behaviour of a conventional optical microscope, like adjusting magnifications and navigating to any portion of the ima...

    Authors: Marcial García Rojo, Antonio J Gallardo, Lucía González, Carlos Peces, Cristina Murillo, Jesús González and Jose Sacristán
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S23
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  6. Process orientation is one of the essential elements of quality management systems, including those in use in healthcare. Business processes in hospitals are very complex and variable. BPMN (Business Process M...

    Authors: Marcial García Rojo, Elvira Rolón, Luis Calahorra, Felix Óscar García, Rosario Paloma Sánchez, Francisco Ruiz, Nieves Ballester, María Armenteros, Teresa Rodríguez and Rafael Martín Espartero
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S22
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  7. This research was conducted on ten glass slides selected from the histopathology evaluation chickens. Five slides of control's chickens healthy and five slides of chickens infected experimentally with chicken ...

    Authors: Luz García, Victor Bermudez, Mariela Brett, Luzmila Peroza, Juan Landa and Franklin Borregales
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S21
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  8. The present paper will present a survey on features of a number of non-specialized off-the-shelf JPEG2000 viewers, seen from the point of view of digital microscopy. Selected viewers were tested within a numbe...

    Authors: Vincenzo Della Mea, Nicola Bortolotti and Carlo Alberto Beltrami
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S20
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  9. Telepathology is becoming easier to implement in most pathology departments. In fact e-mail image transmit can be done from almost any pathologist as a simplistic telepathology system. We tried to develop a wa...

    Authors: Luis Alfaro and MaJosé Roca
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S19
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  10. This article presents a comparative study between different colour models (RGB, HSI and CIEL*a*b*) applied to a very large microscopic image analysis. Such analysis of different colour models is needed in orde...

    Authors: Gloria Bueno, Roberto González, Oscar Déniz, Jesús González and Marcial García-Rojo
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S18
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  11. Historically, histopathology evaluation is performed by a pathologist generating a qualitative assessment on thin tissue sections on glass slides. In the past decade, there has been a growing interest for tool...

    Authors: Coralie Apfeldorfer, Kristina Ulrich, Gareth Jones, David Goodwin, Susie Collins, Emanuel Schenck and Virgile Richard
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S16
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  12. Since their introduction in 1999, fully automated, high speed, high-resolution whole slide imaging devices have become increasing more reliable, fast and capable. While by no means perfect, these devices have ...

    Authors: John Gilbertson and Yukako Yagi
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S14
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  13. This study examined the effect of tissue section thickness and consistency – parameters outside the direct control of the imaging devices themselves – on WSI capture speed and image quality. Preliminary data i...

    Authors: Yukako Yagi and John R Gilbertson
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S12
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  14. Automated image analysis, measurements of virtual slides, and open access electronic measurement user systems require standardized image quality assessment in tissue-based diagnosis.

    Authors: Klaus Kayser, Jürgen Görtler, Konradin Metze, Torsten Goldmann, Ekkehard Vollmer, Masoud Mireskandari, Zdravko Kosjerina and Gian Kayser
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S11
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  15. The Hypertext atlas of Dermatopathology, the Atlas of Fetal and Neonatal Pathology and Hypertext atlas of Pathology (this one in Czech only) are available at

    Authors: Josef Feit, Luděk Matyska, Vladimír Ulman, Lukáš Hejtmánek, Hana Jedličková, Marta Ježová, Mojmír Moulis and Věra Feitová
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S10
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  16. Hypertext atlas of fetal and neonatal pathology is a free resource for pregraduate students of medicine, pathologists and other health professionals dealing with prenatal medicine. The atlas can be found at

    Authors: Marta Ježová, Katarína Múčková, Ondřej Souček, Josef Feit and Pavel Vlašín
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S9
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  17. The technological development of telemedicine has performed important progress, assuming a diagnostic relief role inside of the processes. Among the fields in fast evolution, telepathology is placed among thos...

    Authors: Roberto Mencarelli, Adriano Marcolongo and Alessio Gasparetto
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S7
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  18. We started to use virtual slide (VS) and virtual microscopy (VM) systems for quick frozen intra-operative telepathology diagnosis in Kyoto, Japan. In the system we used a digital slide scanner, VASSALO by CLAR...

    Authors: Yasunari Tsuchihashi, Terumasa Takamatsu, Yukimasa Hashimoto, Tooru Takashima, Kooji Nakano and Setsuya Fujita
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S6
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  19. Nowadays, there is no standard solution for acquiring, archiving and communication of Pathology digital images. In addition, there does not exist any commercial Pathology Information System (LIS) that can mana...

    Authors: Carlos Peces, Marcial García-Rojo, José Sacristán, Antonio José Gallardo and Ambrosio Rodríguez
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S5
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  20. Application of telemedicine systems to cover distant geographical areas has increased recently. However, the potential usefulness of similar systems for creation of national networks does not seem to be widely...

    Authors: Thomas Schrader and Ekaterina Kldiashvili
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S4
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  21. Telepathology recently entered a new era with the introduction of digital microscopes combined with Internet technology. The microscope allows viewing real time of whole slide (macro) as well as different chos...

    Authors: Lech Banach, Andrzej Stepien, Johann Schneider and Elizabeth Wichrzycka-Lancaster
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S3
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  22. Pathological examination includes gross & microscopic examinations at different magnification. Through the steps of examination, we obtain many images that can be used for telepathology. Telepathology is the p...

    Authors: Essam Ayad and Francesco Sicurello
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S2
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  23. In the last 10 years, whole slide imaging (WSI) has seen impressive progress not only in image quality and scanning speed but also in the variety of systems available to pathologists. However, we have noticed ...

    Authors: Yukako Yagi and John R Gilbertson
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S1
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  25. Adult granulosa cell tumors of the ovary (GCTs) are sex cord stromal tumors of unpredictable behaviour. Up to now, the prediction of the relapsing/malignant potential remains difficult. CD56 (NCAM) in GCTs was...

    Authors: Hans-Ullrich Völker, Sabine Engert, Andreas Cramer, Melanie Schmidt, Ulrike Kämmerer, Hans-Konrad Müller-Hermelink and Stefan Gattenlöhner
    Citation: Diagnostic Pathology 2008 3:29
    Content type: Research Published on:

  26. A variety of novel endometrial ablation technologies are now in routine use. A subset of uteri that had previously undergone these treatments will ultimately be evaluated by the pathologist. However, the full ...

    Authors: Oluwole Fadare, Sa A Wang and Idris L Renshaw
    Citation: Diagnostic Pathology 2008 3:28
    Content type: Short report Published on:

  27. In this short report we illustrate a case of extensive sodium polystyrene sulfonate (SPS) aspiration as an immediate cause of death in a terminally ill patient. SPS is a cation exchange resin utilized to decre...

    Authors: Luis F Gonzalez-Cuyar, Nathaniel B Cresswell and Allen P Burke
    Citation: Diagnostic Pathology 2008 3:27
    Content type: Case Report Published on:

  29. The molecular age histopathologist of today is practicing pathology in a totally different scenario than the preceding generations did. Histopathologists stand, as of now, on the cross roads of a traditional '...

    Authors: Biman Saikia, Kirti Gupta and Uma N Saikia
    Citation: Diagnostic Pathology 2008 3:25
    Content type: Commentary Published on:

  30. Intravascular lesions of the hand comprise reactive and neoplastic entities. The clinical diagnosis of such lesions is often difficult, and usually requires pathologic examination. We present the largest serie...

    Authors: Liron Pantanowitz and Wayne H Duke
    Citation: Diagnostic Pathology 2008 3:24
    Content type: Short report Published on:

  31. Nm23 protein is a metastasis suppressor protein, expressed in all tissues. Reduced Nm23 expression is related to a high incidence of lymph node and distant metastasis and poor prognosis in patients with cancer...

    Authors: Amanjit Bal, Kusum Joshi, Rajesh Logasundaram, BD Radotra and Rajinder Singh
    Citation: Diagnostic Pathology 2008 3:23
    Content type: Short report Published on:

  32. Angiolymphoid hyperplasia with eosinophilia (ALHE) is a vasocentric process characterized by infiltrates of lymphocytes and eosinophils, usually affecting the muscular arteries of the head and neck. Currently ...

    Authors: Luis F Gonzalez-Cuyar, Fabio Tavora, X Frank Zhao, Guanghua Wang, Aaron Auerbach, Nadine Aguilera and Allen P Burke
    Citation: Diagnostic Pathology 2008 3:22
    Content type: Case Report Published on:

  34. This short report discusses a case of solitary colonic polypoid ganglioneuroma associated with melanosis coli in a woman with no systemic manifestations. To our knowledge this is the first ganglioneuroma repor...

    Authors: Isabel Maria Mendez, Teresa Pereda, Francisco Javier Rodriguez, Rafael Funez and Andres Sanchez
    Citation: Diagnostic Pathology 2008 3:20
    Content type: Short report Published on:

  35. Extra-hepatic biliary atresia (EHBA) is an important cause of neonatal cholestasis. Several infectious agents have been proposed as etiologic factors such as Rotavirus and Reovirus. There is limited data on th...

    Authors: Fatemeh Mahjoub, Reza Shahsiah, Farid Azmoudeh Ardalan, Guiti Iravanloo, Mehri Najafi Sani, Abdolmajid Zarei, Maryam Monajemzadeh, Fatemeh Farahmand and Setareh Mamishi
    Citation: Diagnostic Pathology 2008 3:19
    Content type: Research Published on:

  38. The extent of enhanced bone marrow angiogenesis in chronic lymphocytic leukemia (CLL) and relationship to proangiogenic factors and prognostic indicators is largely unexplored.

    Authors: John L Frater, Neil E Kay, Charles L Goolsby, Susan E Crawford, Gordon W Dewald and LoAnn C Peterson
    Citation: Diagnostic Pathology 2008 3:16
    Content type: Research Published on:

  39. Liposarcomas are among the most common sarcomas of adult life. Pleomorphic liposarcoma, characterized by pleomorphic lipoblasts, is the rarest subtype. To our knowledge only three cases of pleomorphic liposarc...

    Authors: Luka Brčić, Antonija Jakovčević, Lovorka Batelja Vuletić, Dubravko Orlić and Sven Seiwerth
    Citation: Diagnostic Pathology 2008 3:15
    Content type: Case Report Published on:

  40. Meningioma, craniopharyngeoma and glioma are mainly intracranial lesions. Nevertheless, in rare cases these entities may occur solely as extracranial lesions that may present as intranasal/sinusoidal masses, w...

    Authors: Susan Arndt, Thorsten Wiech, Irina Mader, Antje Aschendorff and Wolfgang Maier
    Citation: Diagnostic Pathology 2008 3:14
    Content type: Case Report Published on:

  43. Pseudosarcomatous myofibroblastic lesions of the urinary bladder are relatively rare entities of an uncertain pathogenesis and benign indolent nature.

    Authors: Alexandros Lekas, Aikaterini Parasi, Thomas G Papathomas, Athanasios G Papatsoris, Maria Rozaria Mennonna, Michail Chrisofos, Charalambos Deliveliotis and Andreas C Lazaris
    Citation: Diagnostic Pathology 2008 3:11
    Content type: Case Report Published on:

  44. Several conditions are considered in differential diagnosis of neonatal cholestasis. Of these the most important is extrahepatic biliary atresia (EHBA), while prompt diagnosis and surgical correction of obstru...

    Authors: Fatemeh E Mahjoub, Reza Hadizadeh Khairkhah, Mehri Najafi Sani, Guiti Irvanloo and Maryam Monajemzadeh
    Citation: Diagnostic Pathology 2008 3:10
    Content type: Research Published on:

  45. Sickle cell nephropathy (SCN) is an important cause of mortality in patients with sickle cell disease. SCA with systemic lupus erythematosus (SLE) is known in children and less common in adults, however diffus...

    Authors: Kamal V Kanodia, Aruna V Vanikar, Kamal R Goplani, Sonia B Gupta and Hargovind L Trivedi
    Citation: Diagnostic Pathology 2008 3:9
    Content type: Case Report Published on:

  46. Adamantinoma is a primary low-grade, malignant bone tumor that is predominantly located in the mid-portion of the tibia. The etiology of the tumor is still a matter of debate. The initial symptoms of adamantin...

    Authors: Deepali Jain, Vijay K Jain, Rakesh K Vasishta, Prabhat Ranjan and Yashwant Kumar
    Citation: Diagnostic Pathology 2008 3:8
    Content type: Review Published on:

  47. Infiltrating myoepithelial carcinoma remains a rarely encountered lesion of the breast. The few cases that have surfaced firmly document the histopathology of this tumor, but its cytologic characteristics seem...

    Authors: Daniel Lingamfelter, Yayan Chen, Kiyoe Kure and Kamani Lankachandra
    Citation: Diagnostic Pathology 2008 3:7
    Content type: Case Report Published on:

  48. In this article, the authors briefly review the historical evolution of the various putative precursor lesions for Type II endometrial cancers, with an emphasis on the newly defined "Endometrial Glandular Dysp...

    Authors: Oluwole Fadare and Wenxin Zheng
    Citation: Diagnostic Pathology 2008 3:6
    Content type: Review Published on:

  50. Ichthyosis uteri is a rare condition in which the entire surface of the endometrium is replaced by stratified squamous epithelium. Though the condition often is considered as benign, anaplastic and dysplastic ...

    Authors: Kanchan Murhekar, Urmila Majhi, V Sridevi and T Rajkumar
    Citation: Diagnostic Pathology 2008 3:4
    Content type: Case Report Published on:
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