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COVID-19 and impact on peer review

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  1. Papillary renal cell carcinoma (RCC) represents a rare tumor, which is divided, based on histological criteria, into two subtypes. In contrast to type I papillary RCC type II papillary RCC shows a worse progno...

    Authors: Carl Ludwig Behnes, Bernhard Hemmerlein, Arne Strauss, Heinz-Joachim Radzun and Felix Bremmer
    Citation: Diagnostic Pathology 2012 7:95
    Content type: Research Published on:

  2. L1 cell adhesion molecule (L1CAM), as a member of the immunoglobulin superfamily, has recently been observed in a variety of human malignancies. However, no data of L1CAM are available for hepatocellular carci...

    Authors: Xiaodong Guo, Lu Xiong, Lin Zou, Ting Sun, Jing Zhang, Hanwei Li, Ruiyun Peng and Jingmin Zhao
    Citation: Diagnostic Pathology 2012 7:96
    Content type: Research Published on:

  3. To distinguish between malignant and benign lesions of the thyroid gland histological demonstration is often required since the fine-needle aspiration biopsy method applied pre-operatively has some limitations...

    Authors: Leandro Luongo de Matos, Adriana Braz Del Giglio, Carolina Ogawa Matsubayashi, Michelle de Lima Farah, Auro Del Giglio and Maria Aparecida da Silva Pinhal
    Citation: Diagnostic Pathology 2012 7:97
    Content type: Review Published on:

  6. Autoimmune sclerosing cholangitis is an overlap syndrome characterized by features of both autoimmune hepatitis and primary sclerosing cholangitis, the latter usually involving the large bile ducts. Autoimmune...

    Authors: Erling Peter Larsen, Allan Bayat and Mogens Vyberg
    Citation: Diagnostic Pathology 2012 7:100
    Content type: Case Report Published on:

  7. In this study, the clinical and morphological features of vesiculobullous lesions observed in Kaposi sarcoma are analyzed, and the features of bullous Kaposi sarcoma cases are emphasized.

    Authors: Nilüfer Onak Kandemir, Figen Barut, Banu Doğan Gün, Nilgün Solak Tekin, Sevinç Hallaç Keser and Şükrü Oğuz Özdamar
    Citation: Diagnostic Pathology 2012 7:101
    Content type: Research Published on:

  8. Neuroendocrine tumor (NET) in adenoma of the gastrointestinal tract is a rare mixed glandular-endocrine neoplasm and has uncommonly been described mostly in the colon. Histologically, this tumor is composed of...

    Authors: Sun-Mi Lee, Soomin Ahn, Yun Kyung Lee, Kee-Taek Jang, Cheol Keun Park and Kyoung-Mee Kim
    Citation: Diagnostic Pathology 2012 7:102
    Content type: Case Report Published on:

  9. Protein kinase RNA (PKR-regulated) is a double-stranded RNA activated protein kinase whose expression is induced by interferon. The role of PKR in cell growth regulation is controversial, with some studies sup...

    Authors: Amal A Mohamed, Ola H Nada and Mohamed A El Desouky
    Citation: Diagnostic Pathology 2012 7:103
    Content type: Research Published on:

  10. The main focus of several studies concerned with cancer progression and metastasis is to analyze the mechanisms that allow cancer cells to interact and quickly adapt with their environment. Integrins, a family...

    Authors: Petra Barros dos Santos, Juliana S Zanetti, Alfredo Ribeiro-Silva and Eduardo IC Beltrão
    Citation: Diagnostic Pathology 2012 7:104
    Content type: Research Published on:

  11. Glandular lesions are often problematic for diagnostic cervical pathology. The survival of patients with adenocarcinoma is significantly poorer than that of patient with squamous cell carcinoma. One reason for...

    Authors: Johji Imura, Yoshiaki Uchida, Kazuhiro Nomoto, Kazuhito Ichikawa, Shigeki Tomita, Tatsuo Iijima and Takahiro Fujimori
    Citation: Diagnostic Pathology 2012 7:105
    Content type: Research Published on:

  12. The current paper describes a case of prostatic adenocarcinoma metastatic to the skin presenting as an extrammamary Paget's disease, a very rare and poorly characterised morphological entity. We report a case ...

    Authors: Eugen Bogdan Petcu, Aldo Gonzalez-Serva, Robert G Wright, Mark Slevin and Klara Brinzaniuc
    Citation: Diagnostic Pathology 2012 7:106
    Content type: Case Report Published on:

  13. Persistent polyclonal B-cell lymphocytosis (PPBL) is rare and intriguing hematological disorder predominantly reported in young to middle- aged smoking women. It is characterized by persistent moderate polyclo...

    Authors: Ping Sun and Ridas Juskevicius
    Citation: Diagnostic Pathology 2012 7:107
    Content type: Case Report Published on:

  14. We present a case of a 62-year-old man who underwent total hip arthroplasty for treatment of pathologic femoral neck fracture associated with adefovir dipivoxil-induced osteomalacia. He had a 13-month history ...

    Authors: Motoyuki Tanaka, Takao Setoguchi, Yasuhiro Ishidou, Yoshiya Arishima, Masataka Hirotsu, Yoshinobu Saitoh, Shunsuke Nakamura, Hironori Kakoi, Satoshi Nagano, Masahiro Yokouchi, Junichi Kamizono and Setsuro Komiya
    Citation: Diagnostic Pathology 2012 7:108
    Content type: Case Report Published on:

  15. Pathologic diagnosis of stage I idiopathic membranous nephropathy (MN-I) requires electron microscopy or immunohistochemistry that shows a glomerular capillary staining pattern of IgG and C3. However, it is no...

    Authors: Rui Zhang, Zhi-yong Zheng, Jian-song Lin, Li-juan Qu and Feng Zheng
    Citation: Diagnostic Pathology 2012 7:109
    Content type: Research Published on:

  16. Determining the primary site of metastatic cancer with confidence can be challenging. Pathologists commonly use a battery of immunohistochemical (IHC) stains to determine the primary site. Gene expression prof...

    Authors: Anand Kulkarni, Raji Pillai, Ashley M Ezekiel, W David Henner and Charles R Handorf
    Citation: Diagnostic Pathology 2012 7:110
    Content type: Short report Published on:

  17. Previous studies have demonstrated that claudin-6 functions as a cancer suppressor in human MCF-7 breast cancer cells. The growth inhibitory effect could be attributed to inhibition of cell proliferation and i...

    Authors: Yaxiong Guo, Xiaoming Xu, Zhijing Liu, Ting Zhang, Xiaowei Zhang, Liping Wang, Min Wang, Yuanyuan Liu, Yan Lu, Yunpeng Liu and Chengshi Quan
    Citation: Diagnostic Pathology 2012 7:111
    Content type: Research Published on:

  19. Giant cell angioblastoma (GCAB) is an extremely rare soft tissue tumor of early childhood and only five cases have been described to date. As such the clinical, pathological, and prognostic features are poorly...

    Authors: Rong-Jun Mao, Zhi-Ming Jiang, Hui-Zhen Zhang, Xiong-Zeng Zhu and Qing-Ling Zhang
    Citation: Diagnostic Pathology 2012 7:113
    Content type: Case Report Published on:

  20. Primary lymphoma of adrenal glands is rare, and non-B-cell lymphoma associated with pyothorax is also very rare. Here we report the first autopsy case of non-B-cell lymphoma in bilateral adrenal glands of a 79...

    Authors: Tomohide Tsukahara, Akira Takasawa, Masaki Murata, Kazuyoshi Okumura, Masato Nakayama, Noriyuki Sato and Tadashi Hasegawa
    Citation: Diagnostic Pathology 2012 7:114
    Content type: Case Report Published on:

  21. Special AT-rich sequence-binding protein 1 (SATB1) is a global gene regulator that has been reported to confer malignant behavior and associate with poor prognosis in several cancer forms. SATB1 expression has...

    Authors: Björn Nodin, Henrik Johannesson, Sakarias Wangefjord, Darran P O’Connor, Kajsa Ericson Lindquist, Mathias Uhlén, Karin Jirström and Jakob Eberhard
    Citation: Diagnostic Pathology 2012 7:115
    Content type: Research Published on:

  22. Madelung’s disease or multiple symmetric lipomatosis (MSL) is a rare disorder of unknown etiology which typically presents symmetrically subcutaneous accumulation of non-encapsulated adipose tissue which slowl...

    Authors: Maddalena Borriello, Alessandro Lucidi, Arnaldo Carbone, Vito Iannone and Gabriella Ferrandina
    Citation: Diagnostic Pathology 2012 7:116
    Content type: Case Report Published on:

  23. Perivascular epithelioid cell (PEC) tumors (PEComas) are a family of related mesenchymal tumors composed of PECs which co-express melanocytic and smooth muscle markers. Although their distinctive histologic, i...

    Authors: Chia-Lang Fang, Yun-Ho Lin and Wei-Yu Chen
    Citation: Diagnostic Pathology 2012 7:117
    Content type: Case Report Published on:

  24. Epithelioid angiosarcoma of the parotid gland is rare, and may pose a great diagnostic challenge. We report a case of primary epithelioid angiosarcoma in a 64-year-old male without history of radiation. The hi...

    Authors: Xu-Yong Lin, Yang Liu, Yong Zhang, Juan-Han Yu and En-Hua Wang
    Citation: Diagnostic Pathology 2012 7:118
    Content type: Case Report Published on:

  25. This study consisted of two parts. One part was to analyze the survival rates of adenoid cystic carcinoma (ACC) in Chinese and explain the difference between our data and the literature. The other was to analy...

    Authors: Quan Zhou, Hong Chang, Hongkai Zhang, Yiding Han and Honggang Liu
    Citation: Diagnostic Pathology 2012 7:119
    Content type: Research Published on:

  26. To evaluate the expression and differential significance of c-Jun, p73, Casp-9 and N-ras in thymic epithelial tumors (TETs) with the aim to provide useful information for tumor biology and prospective therapy.

    Authors: Yuqing Ma, Qiaoxin Li, Wenli Cui, Na Miao, Xia Liu, Wei Zhang, Chen Zhang and Jian Wang
    Citation: Diagnostic Pathology 2012 7:120
    Content type: Research Published on:

  28. Angiomyolipoma (AML) is a rare mesenchymal neoplasm of the tumor, composed of a varying heterogeneous mixture of three tissue components: blood vessels, smooth muscle and adipose cells. Hepatic AML may demonst...

    Authors: Yang Liu, Jian Wang, Xu-Yong Lin, Hong-Tao Xu, Xue-shan Qiu and En-Hua Wang
    Citation: Diagnostic Pathology 2012 7:122
    Content type: Case Report Published on:

  29. Malignant melanoma involving the respiratory tract is nearly always metastatic in origin, and primary tumors are very rare. To our knowledge, about 30 cases have been reported in the English literature, one of...

    Authors: Li Gong, Xiao-Yan Liu, Wen-Dong Zhang, Shao-Jun Zhu, Li Yao, Xiu-Juan Han, Miao Lan, Yan-Hong Li and Wei Zhang
    Citation: Diagnostic Pathology 2012 7:123
    Content type: Case Report Published on:

  30. In many tumors including ovarian cancer, cell proliferation and apoptosis are important in pathogenesis and there are many alterations in most of the genes related to the cell cycle. This study was designed to...

    Authors: Hatice Ozer, GoncaImir Yenicesu, Sema Arici, Meral Cetin, Ersin Tuncer and Ali Cetin
    Citation: Diagnostic Pathology 2012 7:124
    Content type: Research Published on:

  31. Primary mesenchymal chondrosarcoma of the kidney is rare, and it shows distinct undifferentiated tumor cells and well differentiated cartilagenous components. Also assident infiltrating urothelial carcinoma of...

    Authors: Hua Xu, MuMin Shao, HuiLi Sun and ShunMin Li
    Citation: Diagnostic Pathology 2012 7:125
    Content type: Case Report Published on:

  32. Neuroendocrine tumors are a heterogeneous group of neoplasms that arise from neuroendocrine cells. Primary renal neuroendocrine tumors are among the most unusual of all renal neoplasms, since neuroendocrine ce...

    Authors: Qingfu Zhang, Jian Ming, Siyang Zhang and Xueshan Qiu
    Citation: Diagnostic Pathology 2012 7:126
    Content type: Case Report Published on:

  34. Langerhans cell sarcoma is a rare and aggressive high grade hematopoietic neoplasm with a dismal prognosis. It has a unique morphological and immunotypic profile with a CD1a/ langerin/S100 + phenotype. T cell ...

    Authors: Zhaodong Xu, Ruth Padmore, Carolyn Faught, Lisa Duffet and Bruce F Burns
    Citation: Diagnostic Pathology 2012 7:128
    Content type: Case Report Published on:

  36. Multinucleated giant cell-containing tumors and pseudotumors of bone represent a heterogeneous group of benign and malignant lesions. Differential diagnosis can be challenging, particularly in instances of lim...

    Authors: Nawal Hammas, Chbani Laila, Alaoui Lamrani My Youssef, El Fatemi Hind, Taoufiq Harmouch, Tizniti Siham and Amarti Afaf
    Citation: Diagnostic Pathology 2012 7:130
    Content type: Research Published on:

  37. World Health Organization (WHO) criteria are commonly used to diagnose plasma cell myeloma (PCM); however, these criteria are complex and require several laboratory parameters. For differentiating reactive pla...

    Authors: Shoko Nakayama, Taiji Yokote, Yuji Hirata, Kazuki Iwaki, Toshikazu Akioka, Takuji Miyoshi, Ayami Takayama, Uta Nishiwaki, Yuki Masuda, Toshiyuki Ikemoto, Hidema Tanaka, Yasuichiro Nishimura, Motomu Tsuji and Toshiaki Hanafusa
    Citation: Diagnostic Pathology 2012 7:131
    Content type: Research Published on:

  38. Pancreatic neuroendocrine tumors are a rare entity with an incidence between 2 per million to 5 per 100 000. Association with pancreatitis (acute or chronic) is rare and is considered to be determined by the t...

    Authors: Valeriu Surlin, Sandu Ramboiu, Mirela Ghilusi and Iancu Emil Plesea
    Citation: Diagnostic Pathology 2012 7:132
    Content type: Case Report Published on:

  39. CD20-positive T-cell lymphoma is extremely rare and only two cases of CD20-positive NK/T-cell lymphoma with aggressive clinical courses have been described in the literature. We present a case of unusual NK/T-...

    Authors: Qing-ping Jiang, Shao-yan Liu, Yue-xin Yang, Xue-xian Tan, Juan Peng, Zhong-tang Xiong and Zhi Li
    Citation: Diagnostic Pathology 2012 7:133
    Content type: Case Report Published on:

  40. Computer-based analysis of digitalized histological images has been gaining increasing attention, due to their extensive use in research and routine practice. The article aims to contribute towards the descrip...

    Authors: Harshita Sharma, Alexander Alekseychuk, Peter Leskovsky, Olaf Hellwich, RS Anand, Norman Zerbe and Peter Hufnagl
    Citation: Diagnostic Pathology 2012 7:134
    Content type: Research Published on:

  42. Catechol-O-methyltransferase (COMT) is one of the most important enzymes involved in estrogen metabolism and its functional genetic polymorphisms may be associated with breast cancer (BC) risk. Many epidemiologic...

    Authors: Xue Qin, Qiliu Peng, Aiping Qin, Zhiping Chen, Liwen Lin, Yan Deng, Li Xie, Juanjuan Xu, Haiwei Li, Taijie Li, Shan Li and Jinmin Zhao
    Citation: Diagnostic Pathology 2012 7:136
    Content type: Research Published on:

  43. Mucoepidermoid carcinoma is a common malignant epithelial tumor of salivary glands, but relatively rare in lung. The histological features of mucoepidermoid carcinoma of the lung are similar to its counterpart...

    Authors: Hong-Tao Xu, Xu-Yong Lin, Qing-Chang Li and En-Hua Wang
    Citation: Diagnostic Pathology 2012 7:137
    Content type: Case Report Published on:

  44. In this study we report the prevalence of antiretroviral drug resistant HIV-1 genotypes of virus isolated from Djiboutian patients who failed first-line antiretroviral therapy (ART) and from ART naïve patients.

    Authors: Aden Elmi Abar, Asma Jlizi, Houssein Youssouf Darar, Mohamed Ali Ben Hadj Kacem and Amine Slim
    Citation: Diagnostic Pathology 2012 7:138
    Content type: Research Published on:

  46. Leiomyomas are benign tumours that originate from smooth muscles. They are often seen in the uterus, but also in the renal pelvis, bladder, spermatic cord, epididymis, prostate, scrotum or the glans penis. Lei...

    Authors: Felix Bremmer, Felix J Kessel, Carl L Behnes, Lutz Trojan and Elmar Heinrich
    Citation: Diagnostic Pathology 2012 7:140
    Content type: Case Report Published on:

  47. To investigate the expression of matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of metallopropteinase-1 (TIMP-1) in the renal allografts of patients with chronic active antibody-mediated rejection (AM...

    Authors: Qiang Yan, Weiguo Sui, Baoyao Wang, Hequn Zou, Guimian Zou and Hao Luo
    Citation: Diagnostic Pathology 2012 7:141
    Content type: Research Published on:

  48. It has been demonstrated that signals from the inhibitory receptor B and T lymphocyte attenuator (BTLA) are involved in regulating the pathogenesis of infectious diseases. However, the expression and anatomica...

    Authors: Huan Xu, Dayan Cao, Guoning Guo, Zhihua Ruan, Yuzhang Wu and Yongwen Chen
    Citation: Diagnostic Pathology 2012 7:142
    Content type: Research Published on:

  49. A 67-year-old Japanese female was followed up due to prolonged idiopathic thrombocytopenia with non-response to steroid therapy for 4 years, but recent progressive pancytopenia, hypo-albuminemia, and hypo-γ-gl...

    Authors: Sohsuke Yamada, Takashi Tasakil, Naoko Satoh, Atsunori Nabeshima, Shohei Kitada, Hirotsugu Noguchi, Kozue Yamada, Morishige Takeshita and Yasuyuki Sasaguri
    Citation: Diagnostic Pathology 2012 7:143
    Content type: Case Report Published on:

  50. Colloid cysts are rare congenital, intracranial neoplasms, commonly located in the third ventricle. Colloid cysts are endodermal congenital malformations. The cysts commonly range in size from 1–2 cm in diamet...

    Authors: Emanuela Turillazzi, Stefania Bello, Margherita Neri, Irene Riezzo and Vittorio Fineschi
    Citation: Diagnostic Pathology 2012 7:144
    Content type: Case Report Published on:
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