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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Emerging evidences indicate that dysregulated long non-coding RNAs (lncRNAs) are implicated in cancer tumorigenesis and progression. LncRNA ANRIL has been shown to promote the progression of gastric cancer. Ho...

    Authors: Ling Lin, Zhi-Tao Gu, Wen-Hu Chen and Ke-Jian Cao
    Citation: Diagnostic Pathology 2015 10:14
    Content type: Research Published on:

  8. Malignant germ cell tumours are the most common malignant tumours in young men. They are histologically divided into seminomas and non-seminomas. Non-seminomas are further subdivided into embryonic carcinomas,...

    Authors: Felix Bremmer, Philipp Ströbel, Hubertus Jarry, Jasmin Strecker, Nadine Gaisa, Arne Strauß, Stefan Schweyer, Heinz-Joachim Radzun and Carl-Ludwig Behnes
    Citation: Diagnostic Pathology 2015 10:7
    Content type: Research Published on:

  9. C3 glomerulopathy (C3GP) is characterized by deposition of complement C3 with absence/traces of immunoglobulins in the glomeruli and categorized into dense deposit disease (DDD), C3 glomerulonephritis (C3GN), ...

    Authors: Ganesh Kumar Viswanathan, Ritambhra Nada, Ashwani Kumar, Raja Ramachandran, Charan Singh Rayat, Vivekanand Jha, Vinay Sakhuja and Kusum Joshi
    Citation: Diagnostic Pathology 2015 10:6
    Content type: Research Published on:

  10. The association of systemic mastocytosis (SM) with a non-mast cell haematological neoplasm represents a specific subtype of mastocytosis termed systemic mastocytosis with associated haematological non-mast cel...

    Authors: Gorana Gasljevic, Biljana Grcar-Kuzmanov, Alenka Grosel, Matjaz Sever, Barbara Gazic and Veronika Kloboves-Prevodnik
    Citation: Diagnostic Pathology 2015 10:5
    Content type: Case Report Published on:

  11. Immunohistochemistry (IHC) for napsin A has been widely used to support a diagnosis of lung adenocarcinoma with high sensitivity. In this study, we evaluated immunoreactivity for napsin A in a broad spectrum o...

    Authors: Bing Zhu, Stephen M Rohan and Xiaoqi Lin
    Citation: Diagnostic Pathology 2015 10:4
    Content type: Research Published on:

  12. Few larger studies have evaluated the long-term outcome after a diagnosis of papillary urothelial neoplasm of low malignant potential (PUNLMP), demonstrating a broad range of recurrence and progression rates. ...

    Authors: Jay P Maxwell, Cheng Wang, Nicholas Wiebe, Asli Yilmaz and Kiril Trpkov
    Citation: Diagnostic Pathology 2015 10:3
    Content type: Research Published on:

  13. Cytogenetic analysis has detected an accumulation of genetic lesions in oral cancers. Numerical changes in chromosome 17 might be associated with an up-regulation of p53 gene, and could contribute to critical ...

    Authors: Walid Zedan, Mohamed I Mourad, Sherin M Abd El-Aziz, Nagla M Salamaa and Asem A Shalaby
    Citation: Diagnostic Pathology 2015 10:2
    Content type: Research article Published on:

  14. Evaluate the performance of the Focalpoint system in identifying and classifying cervical cytology alterations from samples collected from patients treated with Radiotherapy (RT).

    Authors: Maíra Degiovani Stein, José Humberto T G Fregnani, Cristovam Scapulatempo-Neto and Adhemar Longatto-Filho
    Citation: Diagnostic Pathology 2015 10:1
    Content type: Research Published on:

  15. MicroRNAs (miRNAs) are endogenous small (19–24 nt long) noncoding RNAs that regulate gene expression in a sequence specific manner. An increasing association between miRNA and cancer has been recently reported...

    Authors: Lizhi Cai and Xi Cai
    Citation: Diagnostic Pathology 2014 9:1000
    Content type: Research Published on:

  18. Mammography screen-detected breast cancers have a better prognosis than predicted from established prognostic markers. A search for additional features that are characteristic for these tumours and their progn...

    Authors: Ying Chen, Tor A Klingen, Elisabeth Wik, Hans Aas, Einar Vigeland, Knut Liestøl, Øystein Garred, Jan Mæhlen, Lars A Akslen and Jon Lømo
    Citation: Diagnostic Pathology 2014 9:230
    Content type: Research Published on:

  19. The aim of this study is to compare the digital images of the tissue biopsy captured with optical microscope using bright field technique under various light conditions. The range of colour's variation in immu...

    Authors: Anna Korzynska, Lukasz Roszkowiak, Dorota Pijanowska, Wojciech Kozlowski and Tomasz Markiewicz
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S13
    Content type: Research Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  20. Validation of digital whole slide images is crucial to ensure that diagnostic performance is at least equivalent to that of glass slides and light microscopy. The College of American Pathologists Pathology and...

    Authors: Matteo Brunelli, Serena Beccari, Romano Colombari, Stefano Gobbo, Luca Giobelli, Andrea Pellegrini, Marco Chilosi, Maria Lunardi, Guido Martignoni, Aldo Scarpa and Albino Eccher
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S12
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  21. Comprehensive spatial assessment of hormone receptor immunohistochemistry staining in digital whole slide images of breast cancer requires accurate detection of positive nuclei within biologically relevant reg...

    Authors: Anne Grote, Mahmoud Abbas, Nina Linder, Hans H Kreipe, Johan Lundin and Friedrich Feuerhake
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S11
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  22. Digital immunohistochemistry (IHC) is one of the most promising applications brought by new generation image analysis (IA). While conventional IHC staining quality is monitored by semi-quantitative visual eval...

    Authors: Aida Laurinaviciene, Benoit Plancoulaine, Indra Baltrusaityte, Raimundas Meskauskas, Justinas Besusparis, Daiva Lesciute-Krilaviciene, Darius Raudeliunas, Yasir Iqbal, Paulette Herlin and Arvydas Laurinavicius
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S10
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  23. Currently available microscope slide scanners produce whole slide images at various resolutions from histological sections. Nevertheless, acquisition area and so visualization of large tissue samples are limit...

    Authors: Benoît Plancoulaine, Myriam Oger, Nicolas Elie, Philippe Belhomme, Paulette Herlin, Abir Nasri, Célia Augé, Mylène Brécin, Jacques Marnay and Catherine Bor-Angelier
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S9
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  24. Digital image analysis (DIA) enables better reproducibility of immunohistochemistry (IHC) studies. Nevertheless, accuracy of the DIA methods needs to be ensured, demanding production of reference data sets. We...

    Authors: Benoît Plancoulaine, Aida Laurinaviciene, Raimundas Meskauskas, Indra Baltrusaityte, Justinas Besusparis, Paulette Herlin and Arvydas Laurinavicius
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S8
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  25. Eosinophilic oesophagitis (EoE) is characterized by the presence of eosinophils in oesophageal mucosa. Other inflammatory cells, mainly lymphocytes, dendritic cells, and mast cells may also play an important r...

    Authors: Marcial García-Rojo, Joaquín Rodríguez Sánchez, Eva de la Santa, Elena Durán, José Luis Ruiz, Antonio Silva, Francisco Javier Rubio, Antonio M Rodríguez, Blas Meléndez, Lucía González and Bartolomé López-Viedma
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S7
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  26. Crowdsourcing, i.e., the outsourcing of tasks typically performed by a few experts to a large crowd as an open call, has been shown to be reasonably effective in many cases, like Wikipedia, the Chess match of ...

    Authors: Vincenzo Della Mea, Eddy Maddalena, Stefano Mizzaro, Piernicola Machin and Carlo A Beltrami
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S6
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  27. Developments in technology, web-based teaching and whole slide imaging have broadened the teaching horizon in anatomic pathology. Creating online learning material including many types of media such as radiolo...

    Authors: Emilie Perron, Maxime Battistella, Béatrice Vergier, Maryse Fiche, Philippe Bertheau and Bernard Têtu
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S5
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  28. Current terminology systems for structured reporting in pathology are more or less focused on tumor pathology. They have not been compiled in a systematic approach, therefore they gather terms of very differen...

    Authors: Gunter Haroske and Thomas Schrader
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S4
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  29. Since microscopic slides can now be automatically digitized and integrated in the clinical workflow, quality assessment of Whole Slide Images (WSI) has become a crucial issue. We present a no-reference quality...

    Authors: David Ameisen, Christophe Deroulers, Valérie Perrier, Fatiha Bouhidel, Maxime Battistella, Luc Legrès, Anne Janin, Philippe Bertheau and Jean-Baptiste Yunès
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S3
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  30. Telepathology may play an important role in pathology consultation and quality control for cancer diagnosis in China, as the country has the largest population of cancer patients worldwide. In 2011, the Pathol...

    Authors: Je Chen, Yahui Jiao, Chaohui Lu, Jun Zhou, Zongjiu Zhang and Chen Zhou
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S2
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  31. The Eastern Quebec Telepathology Network (called Réseau de Télépathologie de l'Est du Québec in French) was created to provide uniform diagnostic telepathology services in a huge territory with low population ...

    Authors: Bernard Têtu, Émilie Perron, Said Louahlia, Guy Paré, Marie-Claude Trudel and Julien Meyer
    Citation: Diagnostic Pathology 2014 9(Suppl 1):S1
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 9 Supplement 1

  32. Previous studies suggested that apolipoprotein A5 (ApoA5) genetic polymorphisms (SNPs) may result in lipid metabolism disorders. Therefore, genetic polymorphisms in ApoA5 may be associated with the occurrence ...

    Authors: Yong Cui, Aihemaiti Kaisaierjiang, Peng Cao, Zhong-Yan Wu and Qing Lv
    Citation: Diagnostic Pathology 2014 9:229
    Content type: Research Published on:

  33. In a number of human malignancies, tumor-associated macrophages (TAMs) are closely involved in tumor progression. On the other hand, dendritic cells (DCs) that infiltrate tumor tissues are involved in tumor su...

    Authors: Mutsuko Omatsu, Toshiaki Kunimura, Tetsuya Mikogami, Akira Shiokawa, Tomoko Nagai, Atsuko Masunaga, Akihiko Kitami, Takashi Suzuki and Mitsutaka Kadokura
    Citation: Diagnostic Pathology 2014 9:215
    Content type: Research Published on:

  34. Gastric cardia adenocarcinoma (GCA) is one of the major causes of cancer related mortality worldwide. We aim to provide new understanding in the pathogenesis of GCA through investigations on gene expression al...

    Authors: Xiaofeng Xu, Lifang Xu, Feng Gao, Jianjiang Wang, Jinsong Ye, Mingxian Zhou, Yunling Zhu and Lan Tao
    Citation: Diagnostic Pathology 2014 9:218
    Content type: Research Published on:

  35. The tumor suppressor protein p16INK4a has been extensively studied in many tumors with very different results, ranging from its loss to its clear overexpression, which may be associated with degree of tumor diffe...

    Authors: Yue Liu, Xiufeng Zhong, Shangtao Wan, Wenxin Zhang, Jianxian Lin, Ping Zhang and Yongping Li
    Citation: Diagnostic Pathology 2014 9:180
    Content type: Research Published on:

  36. We report a case of a 33-year-old man who presented with immunoglobulin (Ig)G4-related disease (IgG4-RD) forming a pseudotumor in the left paratesticular region during oral administration of corticosteroid for...

    Authors: Takashi Karashima, Yoshinori Taniguchi, Tsutomu Shimamoto, Tomoya Nao, Hiroshi Nishikawa, Satoshi Fukata, Masayuki Kamada, Keiji Inoue, Kentaro Oko, Hideki Nakajima, Shigetoshi Sano, Manabu Matsumoto, Naoto Kuroda, Yoshihiro Kamei and Taro Shuin
    Citation: Diagnostic Pathology 2014 9:225
    Content type: Case Report Published on:

  37. Mucinous tubular and spindle cell carcinoma (MTSC) was first recognized as a specific entity in the World Health Organization 2004 classification. The “classic” tumor presentation includes an extracellular blu...

    Authors: Yanling Zhang, Xiang Yong, Qiong Wu, Xiaoli Wang, Qiong Zhang, Shiwu Wu and Donghong Yu
    Citation: Diagnostic Pathology 2014 9:194
    Content type: Case Report Published on:

  38. The histopathological subtype, nuclear grade and presence or absence of comedonecrosis are established as critical elements in the reporting of ductal carcinoma in situ (DCIS) of the breast. The aims of this s...

    Authors: Amanda Arantes Perez, Débora Balabram, Marcio De Almeida Salles and Helenice Gobbi
    Citation: Diagnostic Pathology 2014 9:227
    Content type: Research Published on:

  39. MicroRNA-106b (miR-106b) is a member of the miR-106b ~ 25 cluster. It has been reported that miR-106b acts as an oncogene and is upregulated in many human cancers. However, the prognostic value of miR-106b in ...

    Authors: Bin-Kui Li, Pin-Zhu Huang, Ji-Liang Qiu, Ya-Di Liao, Jian Hong and Yun-Fei Yuan
    Citation: Diagnostic Pathology 2014 9:226
    Content type: Research Published on:

  40. Solitary fibrous tumor is a mesenchymal tumor of fibroblastic type, which can affect any region of the body. Recently, a recurrent gene fusion NAB2-STAT6 has been identified as molecular hallmark. The NAB2-STAT6 ...

    Authors: Rob JC Vogels, Myrella Vlenterie, Yvonne MH Versleijen-Jonkers, Emiel Ruijter, Elise M Bekers, Marian AJ Verdijk, Monique M Link, Johannes J Bonenkamp, Winette TA van der Graaf, Pieter J Slootweg, Albert JH Suurmeijer, Patricia JTA Groenen and Uta Flucke
    Citation: Diagnostic Pathology 2014 9:224
    Content type: Research Published on:

  41. Immunohistochemistry (IHC) is a well-established, widely accepted method in both clinical and experimental parts of medical science. It allows receiving valuable information about any process in any tissue, an...

    Authors: Nickolay Fedchenko and Janin Reifenrath
    Citation: Diagnostic Pathology 2014 9:221
    Content type: Review Published on:

  43. The present study describes the pathologic changes in the brain and the spinal cord of aborted, stillbirth and deformities of newborn lambs infected with viral agents.

    Authors: Javad Javanbakht, Seyed Hossein Mardjanmehr, Abbas Tavasoly and Mohammad Hossein Nazemshirazi
    Citation: Diagnostic Pathology 2014 9:223
    Content type: Research Published on:

    The Retraction Note to this article has been published in Diagnostic Pathology 2016 11:126

  45. In prognosis and therapeutics of adrenal cortical carcinoma (ACC), the selection of the most active areas in proliferative rate (hotspots) within a slide and objective quantification of immunohistochemical Ki6...

    Authors: Hao Lu, Thomas G Papathomas, David van Zessen, Ivo Palli, Ronald R de Krijger, Peter J van der Spek, Winand NM Dinjens and Andrew P Stubbs
    Citation: Diagnostic Pathology 2014 9:216
    Content type: Software Published on:

  46. Pre-clinical evidence shows that fixed dose rate (FDR) infusion of gemcitabine could optimize plasma concentration of gemcitabine, while the clinical efficacy and toxicity of FDR infusion of gemcitabine in adv...

    Authors: Jiqing Xie, Jing Yuan and Laichun Lu
    Citation: Diagnostic Pathology 2014 9:214
    Content type: Research Published on:

  47. Recent technical advances in digital image capture and analysis greatly improve the measurement of protein expression in tissues. Breast cancer biomarkers provide a unique opportunity to utilize digital image ...

    Authors: Arkadiusz Gertych, Sonia Mohan, Shawn Maclary, Sambit Mohanty, Kolja Wawrowsky, James Mirocha, Bonnie Balzer and Beatrice S Knudsen
    Citation: Diagnostic Pathology 2014 9:213
    Content type: Research Published on:

  48. Ectopic crypts, defined as abnormally positioned crypts that have lost their orientation toward the muscularis mucosae, have been suggested to be the best defining histologic feature of traditional serrated ad...

    Authors: Mi-Jung Kim, Eun-Jung Lee, Sung-Min Chun, Se-Jin Jang, Do Sun Kim, Doo Han Lee and Eui Gon Youk
    Citation: Diagnostic Pathology 2014 9:212
    Content type: Research Published on:

  49. Tumour-to-tumour metastasis (TTM) occurs when one tumour metastasises to a separate tumour within the same individual. TTM is observed frequently in breast cancer but has not been described in male breast canc...

    Authors: Susanne Scheipl, Farid Moinfar, Andreas Leithner, Patrick Sadoghi, Mette Jorgensen, Beate Rinner and Bernadette Liegl
    Citation: Diagnostic Pathology 2014 9:203
    Content type: Case Report Published on:

  50. The aim of the present study was to evaluate the influence of tumor necrosis factor-alpha (TNF-α) −308 G > A polymorphism on hepatocellular carcinoma (HCC) risk.

    Authors: Hua Feng, Jing-hua Kuai, Ming-yan Zhang, Guang-chuan Wang, Yong-jun Shi and Jun-yong Zhang
    Citation: Diagnostic Pathology 2014 9:199
    Content type: Research Published on:
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Diagnostic Pathology

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