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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Impaired endometrial receptivity is a major reason for embryo implantation failure. There’s a paucity of information regarding the role of circRNAs on endometrial receptivity. Here, we investigated the functio...

    Authors: Fang Zhao, Yihong Guo, Zhanrong Shi, Menglan Wu, Yuzhen Lv and Wenyue Song
    Citation: Diagnostic Pathology 2021 16:44
    Content type: Research Published on:

  2. Effective workflow management in a diagnostic pathology laboratory is critical to achieve rapid turnover while maintaining high quality. Fluorescence in situ hybridization analysis (FISH) is the preferred tech...

    Authors: Vira Chea, Valerie Pleiner, Viviane Schweizer, Benjamin Herzog, Beata Bode and Marianne Tinguely
    Citation: Diagnostic Pathology 2021 16:42
    Content type: Short report Published on:

  3. The objective was to build a novel method for automated image analysis to locate and quantify the number of cytokeratin 7 (K7)-positive hepatocytes reflecting cholestasis by applying deep learning neural netwo...

    Authors: Nelli Sjöblom, Sonja Boyd, Anniina Manninen, Anna Knuuttila, Sami Blom, Martti Färkkilä and Johanna Arola
    Citation: Diagnostic Pathology 2021 16:41
    Content type: Research Published on:

  4. Patients with COVID-19 can also have enteric symptoms. Here we analyzed the histopathology of intestinal detachment tissue from a patient with COVID-19.

    Authors: Yanling Feng, Dong Zeng, Lvyin Hu, Yuexiang Yang, Shu Song, Yuhan Shi, Jingjing Xu, Wenjuan Guo, Yun Ling, Tangkai Qi, Qingguo Wu, Feng Li, Jilin Cheng and Hongzhou Lu
    Citation: Diagnostic Pathology 2021 16:40
    Content type: Case Report Published on:

  5. Danon disease (DD) is a rare x-linked dominant multisystemic disorder with a clinical triad of severe cardiomyopathy, skeletal myopathy, and mental retardation. It is caused by a defect in the lysosomal-associ...

    Authors: Jiamin Xu, Zhu Li, Yihai Liu, Xinlin Zhang, Fengnan Niu, Hongyan Zheng, Lian Wang, Lina Kang, Kun Wang and Biao Xu
    Citation: Diagnostic Pathology 2021 16:39
    Content type: Case Report Published on:

  6. Gastric cancer (GC) is the 4th most common type of cancer worldwide. Different GC subtypes have unique molecular features that may have different therapeutic methods. The aim of the present study was to invest...

    Authors: Li Zhang, Yinkui Wang, Zhongwu Li, Dongmei Lin, Yiqiang Liu, Linxin Zhou, Dongliang Wang, Aiwen Wu and Ziyu Li
    Citation: Diagnostic Pathology 2021 16:38
    Content type: Research Published on:

  8. Esophageal cancer is one of the most common malignancies among Iranians and is categorized as adenocarcinoma and squamous cell carcinoma. Various environmental and genetic factors are involved in this malignan...

    Authors: Mohammad Reza Abbaszadegan, Negin Taghehchian, Azadeh Aarabi, Faride Akbari, Ehsan Saburi and Meysam Moghbeli
    Citation: Diagnostic Pathology 2021 16:36
    Content type: Research Published on:

  9. Small cell neuroendocrine carcinoma of the prostate (SCNECP) is a rare, aggressive subtype of prostate carcinoma. Most SCNECP arise from conventional prostate adenocarcinoma (CPAC) treated with androgen depriv...

    Authors: Phoenix D. Bell, Aaron R. Huber and Diana Agostini-Vulaj
    Citation: Diagnostic Pathology 2021 16:35
    Content type: Case Report Published on:

  11. Oral squamous cell carcinoma (OSCC) is the most relevant malignant neoplasm among all head and neck tumours due to its high prevalence and unfavourable prognosis. Tumour invasion and metastasis that affect pro...

    Authors: Geovanni Pereira Mitre, Karolyny Martins Balbinot, André Luis Ribeiro Ribeiro, Maria Sueli da Silva Kataoka, Sérgio de Melo Alves Júnior and João de Jesus Viana Pinheiro
    Citation: Diagnostic Pathology 2021 16:33
    Content type: Research Published on:

  12. Solitary Fibrous Tumor (SFT) is a distinct soft tissue neoplasm associated with NAB2-STAT6 gene fusion. It can involve a number of anatomic sites and exhibits a wide spectrum of histological features.

    Authors: Muhammad Usman Tariq, Nasir Ud Din, Jamshid Abdul-Ghafar and Yong-Koo Park
    Citation: Diagnostic Pathology 2021 16:32
    Content type: Review Published on:

  14. Nonsense mutation or inactivation of SMARCA4 (BRG1) is associated with a monomorphic undifferentiated histological appearance in tumors at different sites. The association between SMARCA4 alteration and undiff...

    Authors: Huanli Duan, Wei Gao, Leiming Wang, Feng Cao and Lianghong Teng
    Citation: Diagnostic Pathology 2021 16:30
    Content type: Case Report Published on:

  15. Primary hepatic mucoepidermoid carcinoma (HMEC) is extremely rare and the molecular etiology is still unknown. The CRTC1-MAML2 fusion gene was previously detected in a primary HMEC, which is often associated with...

    Authors: Ping Hou, Xiaoyan Su, Wei Cao, Liping Xu, Rongguiyi Zhang, Zhihao Huang, Jiakun Wang, Lixiang Li, Linquan Wu and Wenjun Liao
    Citation: Diagnostic Pathology 2021 16:29
    Content type: Research Published on:

  16. This study aimed to investigate the association between clinicopathologic factors, mesothelin, and cancer antigen (CA) 125 in endometrial carcinoma.

    Authors: Soichiro Kakimoto, Morikazu Miyamoto, Takahiro Einama, Yasuhiro Takihata, Hiroko Matsuura, Hideki Iwahashi, Hiroki Ishibashi, Takahiro Sakamoto, Taira Hada, Jin Suminokura, Tsubasa Ito, Rie Suzuki, Ayako Suzuki and Masashi Takano
    Citation: Diagnostic Pathology 2021 16:28
    Content type: Research Published on:

  18. TWIST1 and CD105, which contribute to tumor malignancy, are overexpressed in cancers. Accordingly, TWIST1 enhances epithelial-to-mesenchymal transition (EMT) and promotes the formation of cancer stem cells (CS...

    Authors: Fahimeh Fattahi, Leili Saeednejad Zanjani, Somayeh Vafaei, Zohreh Habibi Shams, Jafar Kiani, Marzieh Naseri, Elmira Gheytanchi and Zahra Madjd
    Citation: Diagnostic Pathology 2021 16:26
    Content type: Research Published on:

  19. Fine-needle aspiration (FNA) is a frequently utilized method for the diagnosis of thyroid nodules. Although the technique has clear advantages, the injury caused by the aspiration needle can induce various his...

    Authors: Woo Sung Moon, Myoung Jae Kang, Hyun Jo Youn and Kyoung Min Kim
    Citation: Diagnostic Pathology 2021 16:25
    Content type: Case Report Published on:

  20. The role of Artificial intelligence (AI) which is defined as the ability of computers to perform tasks that normally require human intelligence is constantly expanding. Medicine was slow to embrace AI. However...

    Authors: Zubair Ahmad, Shabina Rahim, Maha Zubair and Jamshid Abdul-Ghafar
    Citation: Diagnostic Pathology 2021 16:24
    Content type: Review Published on:

  21. Kaposiform Hemangioendothelioma (KHE) is a rare vascular tumor of intermediate malignant potential which shows locally aggressive growth but only rarely metastasizes. It is mostly considered to be a tumor of p...

    Authors: Qurratulain Chundriger, Muhammad Usman Tariq, Jamshid Abdul-Ghafar, Arsalan Ahmed and Nasir Ud Din
    Citation: Diagnostic Pathology 2021 16:23
    Content type: Research Published on:

  22. Sialadenoma papilliferum (SP) is an extremely rare benign neoplasm of salivary glands. To explore and define the clinicopathological features of SP, we retrospectively analyzed 89 cases previously reported and...

    Authors: Shuai Chen, Jie Peng, Chuantao Yuan, Lin Sun, Renya Zhang and Yan Sun
    Citation: Diagnostic Pathology 2021 16:22
    Content type: Research Published on:

  23. In lung cancer management, differential diagnosis between multiple primary lung cancer (MPLC) and intrapulmonary metastasis (IMP) is a critical point that is of direct therapeutic and clinical importance. Howe...

    Authors: Changjiang Liu, Chengang Liu, Xiao Zou, Lin Shao, Ying Sun and Yang Guo
    Citation: Diagnostic Pathology 2021 16:21
    Content type: Case Report Published on:

  24. Making the distinction between primary mucinous and metastatic ovarian tumors is often difficult, especially in tumors with a primary source from the gastrointestinal tract, pancreas and biliary tree. The aim ...

    Authors: Pavel Dundr, Naveena Singh, Barbora Nožičková, Kristýna Němejcová, Michaela Bártů and Ivana Stružinská
    Citation: Diagnostic Pathology 2021 16:20
    Content type: Review Published on:

  25. Immunohistochemistry (IHC) remains the gold standard for the diagnosis of pathological diseases. This technique has been supporting pathologists in making precise decisions regarding differential diagnosis and...

    Authors: Yosep Chong, Nishant Thakur, Ji Young Lee, Gyoyeon Hwang, Myungjin Choi, Yejin Kim, Hwanjo Yu and Mee Yon Cho
    Citation: Diagnostic Pathology 2021 16:19
    Content type: Research Published on:

  26. Metastases are common in non-cirrhotic livers but are considered unlikely in the setting of cirrhosis. However, the degree of fibrosis in cirrhosis may vary; thus metastases may still access the liver vasculat...

    Authors: Zaid Mahdi, Mark G. Ettel, Raul S. Gonzalez, John Hart, Lindsay Alpert, Jiayun Fang, Natalia Liu, Suntrea T. Hammer, Nicole Panarelli, Jerome Cheng, Joel K. Greenson, Paul E. Swanson and Maria Westerhoff
    Citation: Diagnostic Pathology 2021 16:18
    Content type: Research Published on:

  27. Patients with head and neck squamous cell carcinoma (HNSCC) can develop lung squamous cell carcinoma (LuSCC), which could be the second primary tumor or HNSCC metastasis. Morphologically it is difficult to dis...

    Authors: Maja Šutić, Jurica Baranašić, Lana Kovač Bilić, Mario Bilić, Antonija Jakovčević, Luka Brčić, Sven Seiwerth, Marko Jakopović, Miroslav Samaržija, Ulrich Zechner and Jelena Knežević
    Citation: Diagnostic Pathology 2021 16:17
    Content type: Short report Published on:

  28. To date, very few studies on clinical-histopathological correlations of cutaneous disorders associated with COVID-19 have been conducted.

    Authors: Angela Patrì, Maria Vargas, Pasquale Buonanno, Maria Carmela Annunziata, Daniela Russo, Stefania Staibano, Giuseppe Servillo and Gabriella Fabbrocini
    Citation: Diagnostic Pathology 2021 16:16
    Content type: Case Report Published on:

  29. A 52-year-old woman presented with shortness of breath and cough. An endobronchial sialolipoma was found at the left entrance of the main bronchus. Sialolipoma is an exceedingly rare type of lipoma reported of...

    Authors: Severino Rey Nodar, Verónica García Yllán, Nohelia Rojas Ferrer, Onay Solis and Hugo D. Boccara
    Citation: Diagnostic Pathology 2021 16:15
    Content type: Case Report Published on:

  30. Succinate dehydrogenase deficient gastrointestinal stromal tumors (SDH-deficient GISTs), which lack KIT or PDGFRA mutations demonstrate unique clinical and pathological features, and they respond poorly to sta...

    Authors: Bei-Bei Lv, Jia-Mei Li, Zhi-Gang Yao, Xian-Kui Cheng, Fu-Xin Ren, Wen-Jing Su, Ye-Jun Qin, Zhou Wang and Zhi-xin Cao
    Citation: Diagnostic Pathology 2021 16:14
    Content type: Case Report Published on:

  31. The consistency of pathologists in the diagnosis of cervical intraepithelial neoplasia (CINs) is not ideal, especially between low- and high-grade squamous intraepithelial lesions (LSIL and HSIL). This study w...

    Authors: Chang Hui, Huimin Bai, Jun Liu, Xuerong Lu, Shuzhen Wang, Zhenyu Zhang, Mulan Jin, Yue Wang and Yuzhen Liu
    Citation: Diagnostic Pathology 2021 16:13
    Content type: Research Published on:

  32. Ovarian clear cell carcinoma (OCCC) is the second subtype of ovarian epithelial carcinoma reported to be closely related to Lynch syndrome (LS). ARID1A mutation is an important pathogenetic mechanism in OCCC t...

    Authors: Huijuan Ge, Yaoxin Xiao, Guangqi Qin, Yanzi Gu, Xu Cai, Wenhua Jiang, Xiaoyu Tu, Wentao Yang and Rui Bi
    Citation: Diagnostic Pathology 2021 16:12
    Content type: Research Published on:

  33. The majority of gastrointestinal tumors are adenocarcinomas. Rarely, there are other types of tumors, such as acinar cell carcinoma, and these are often called pancreatic-type acinar cell carcinomas. Among the...

    Authors: Yuka Ooe, Kishichiro Watanabe, Isaya Hashimoto, Satoshi Takenaka, Toshihiko Ojima, Seiichi Yamamoto and Hisatake Fujii
    Citation: Diagnostic Pathology 2021 16:11
    Content type: Case Report Published on:

  34. Glutathione S-transferase mu 3 (GSTM3) plays a crucial role in tumor progression in various cancers. However, the relationship between GSTM3 expression and the clinical prognosis of esophageal squamous cell ca...

    Authors: Fu Yang, Jing Wen, Kongjia Luo and Jianhua Fu
    Citation: Diagnostic Pathology 2021 16:10
    Content type: Research Published on:

  36. To explore the clinical characteristics and placental pathological changes of pregnant women with 2019 novel coronavirus (CoV) disease (COVID-19) in the third trimester, and to assess the possibility of vertic...

    Authors: Likun Gao, Jiacai Ren, Li Xu, Xiaokang Ke, Lin Xiong, Xiaoli Tian, Cuifang Fan, Honglin Yan and Jingping Yuan
    Citation: Diagnostic Pathology 2021 16:8
    Content type: Case Report Published on:

  38. Histiocytic sarcoma (HS) is a rare neoplasm showing morphological and immunophenotypic features of mature tissue histiocytes. We report a patient with nodal HS exhibiting prominent reactive eosinophilic infilt...

    Authors: Rintaro Ohe, Takanobu Kabasawa, Aya Utsunomiya, Yuka Urano, Takumi Kitaoka, Kazushi Suzuki, Naing Ye Aung, Ichiro Kawamura, Katsushi Tajima, Tomoharu Ishiyama and Mitsunori Yamakawa
    Citation: Diagnostic Pathology 2021 16:6
    Content type: Case Report Published on:

  39. Gastric cancer (GCa) is one of the six major malignancies in the world with low survival rate. Although there are advances in therapeutic approaches, the prognosis of patients with GCa remains not optimistic. ...

    Authors: Zhong Zheng, Jun Li, Junyan An, Yikuan Feng and Lirong Wang
    Citation: Diagnostic Pathology 2021 16:5
    Content type: Research Published on:

  42. IL4Rα and IL13Rα1 are constituents of the type II IL4 receptor. Recently, IL4Rα and IL13Rα1 were reported to have roles in cancer progression and suggested as potential prognostic markers. However, studies on ...

    Authors: Kyoung Min Kim, Usama Khamis Hussein, See-Hyoung Park, Young Jae Moon, Zhongkai Zhang, Asmaa Gamal Ahmed, Ae-Ri Ahn, Ho Sung Park, Jung Ryul Kim and Kyu Yun Jang
    Citation: Diagnostic Pathology 2021 16:2
    Content type: Research Published on:

  43. Anaplastic large cell lymphoma (ALCL) with uniform CD56 expression is a rare condition, that has been described in limited literature, and its clinicopathological features have not yet been well illustrated. T...

    Authors: Bao-Hua Yu, Yan Zhang, Tian Xue, Ruo-Hong Shui, Hong-Fen Lu, Xiao-Yan Zhou, Xiong-Zeng Zhu and Xiao-Qiu Li
    Citation: Diagnostic Pathology 2021 16:1
    Content type: Research Published on:

  44. Identification of somatic mutations in key oncogenes in melanoma is important to lead the effective and efficient use of personalized anticancer treatment. Conventional methods focus on few genes per run and, ...

    Authors: Irene Vanni, Milena Casula, Lorenza Pastorino, Antonella Manca, Bruna Dalmasso, Virginia Andreotti, Marina Pisano, Maria Colombino, Ulrich Pfeffer, Enrica Teresa Tanda, Carla Rozzo, Panagiotis Paliogiannis, Antonio Cossu, Paola Ghiorzo and Giuseppe Palmieri
    Citation: Diagnostic Pathology 2020 15:143
    Content type: Research Published on:

  46. The involvement of circular RNAs (circRNAs) in chemoresistance of tumors has been identified. Herein, this study aims to investigate the role and the underlying mechanism of circ_0003998 in doxorubicin (DOX) r...

    Authors: Xiaomin Li, Jiefeng He, Xiaojing Ren, Haichao Zhao and Haoliang Zhao
    Citation: Diagnostic Pathology 2020 15:141
    Content type: Research Published on:

  48. Pancreatic Solid Pseudopapillary Neoplasms (SPNs) are rare low-grade malignant tumors with a marked preponderance for young females. Objective was to describe the morphology, differential diagnosis, and progno...

    Authors: Nasir Ud Din, Shabina Rahim, Jamshid Abdul-Ghafar, Arsalan Ahmed and Zubair Ahmad
    Citation: Diagnostic Pathology 2020 15:139
    Content type: Research Published on:

  50. High grade basal-like breast carcinomas are triple negative, express basal cytokeratins, and are known for the overall poor prognosis and aggressive behavior. HPV related multiphenotypic sino-nasal carcinoma h...

    Authors: Diana M. Oramas, Diana Bell and Lavinia P. Middleton
    Citation: Diagnostic Pathology 2020 15:137
    Content type: Case Report Published on:
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