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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. The most frequent histological types of rhabdomyosarcoma (RMS) in children are embryonal (ERMS) and alveolar (ARMS) tumours. The majority of ARMS are characterized by the presence of PAX3/7-FOXO1 gene fusion a...

    Authors: Magdalena Kaleta, Anna Wakulińska, Agnieszka Karkucińska-Więckowska, Bożenna Dembowska-Bagińska, Wiesława Grajkowska, Maciej Pronicki and Maria Łastowska
    Citation: Diagnostic Pathology 2019 14:103
    Content type: Research Published on:

  2. Basaloid squamous cell carcinoma (BSCC) is a rare subtype of squamous cell carcinoma with a high rate of distant metastasis. BSCC occurs most commonly in the esophagus, lungs, and head and neck. However, BSCC ...

    Authors: Linxiu Liu, Xuemin Xue and Liyan Xue
    Citation: Diagnostic Pathology 2019 14:102
    Content type: Case Report Published on:

  3. The accurate identification of the tissue of origin is critical for optimal management of cancer patients particularly those who develop multiple malignancies; however, conventional diagnostic methods at times...

    Authors: Chuangzhou Rao, Liangqin Nie, Xiaobo Miao, Analyn Lizaso and Guofang Zhao
    Citation: Diagnostic Pathology 2019 14:101
    Content type: Case Report Published on:

  5. Antibodies targeting the programmed cell death-1 (PD-1)/PD-ligand 1 (PD-1/PD-L1) checkpoint have shown promising clinical activity in patients with advanced urothelial carcinoma (UC). Expression of PD-L1 in UC...

    Authors: Magdalena Zajac, Marietta Scott, Marianne Ratcliffe, Paul Scorer, Craig Barker, Hytham Al-Masri, Marlon C. Rebelatto and Jill Walker
    Citation: Diagnostic Pathology 2019 14:99
    Content type: Research Published on:

  6. Celiac disease (CD) is characterized histologically by inflammation and villous atrophy. Villous atrophy is thought to result from a disruption of epithelial cellular proliferation and death. Epithelial cells ...

    Authors: Michael Lee, Shane Betman, Alina Iuga, Hui-Min Yang, Jude Fleming, Peter H. R. Green, Benjamin Lebwohl and Stephen M. Lagana
    Citation: Diagnostic Pathology 2019 14:98
    Content type: Research Published on:

  8. Ovarian metastatic tumors from lung adenocarcinoma are rare, and a serial study of these tumors is lacking to date. Additionally, a better understanding of the clinicopathological and molecular characteristics...

    Authors: Rui Bi, Qianming Bai, Xiaoli Zhu, Xiaoyu Tu, Xu Cai, Wenhua Jiang, Xiaoli Xu, Shaoxian Tang, Huijuan Ge, Bin Chang, Yufan Cheng, Hualei Gan, Xiaoyan Zhou and Wentao Yang
    Citation: Diagnostic Pathology 2019 14:96
    Content type: Research Published on:

  9. Secretory breast carcinoma is an exceptionally rare type of breast carcinoma. Only 5 cases of pure secretory carcinoma in situ have been reported in English literature. Herein, we reported a rare case of pure ...

    Authors: Ying Yang, Zhiyuan Wang, Guoqing Pan, Shumo Li, Yingying Wu and Liu Liu
    Citation: Diagnostic Pathology 2019 14:95
    Content type: Case Report Published on:

  10. Castleman’s disease (CD) is an uncommon type of benign proliferation of the lymphoid tissue, characterized by local or systemic lymphadenopathy that most frequently appears in the mediastinum; involvement of t...

    Authors: Yunzhu Li, Haixia Zhao, Bingyin Su, Chan Yang, Shurong Li and Wanlei Fu
    Citation: Diagnostic Pathology 2019 14:94
    Content type: Case Report Published on:

  12. A primordial odontogenic tumor (POT) is a rare, benign, mixed epithelial and mesenchymal odontogenic tumor that has been included as a new entity in the latest World Health Organization (WHO) classification (2...

    Authors: Qiaochu Sun, Jae-Seo Lee, Okjoon Kim and Young Kim
    Citation: Diagnostic Pathology 2019 14:92
    Content type: Case Report Published on:

  14. European treatment guidelines for pTa and pT1 urinary bladder urothelial carcinoma depend highly on stage and WHO-grade. Both the WHO73 and the WHO04 grading systems show some intra- and interobserver variabil...

    Authors: Vebjørn Kvikstad, Ok Målfrid Mangrud, Einar Gudlaugsson, Ingvild Dalen, Hans Espeland, Jan P. A. Baak and Emiel A. M. Janssen
    Citation: Diagnostic Pathology 2019 14:90
    Content type: Research Published on:

  15. Follicular dendritic cell sarcoma (FDCS) is a rare malignancy. In addition to the classical histopathologic features, it has also some special morphological variants that can present a challenge in the diagnos...

    Authors: You-Li Wu, Feng Wu, Robinson Ateh Mbako, Yu Zhang, Guang-Jie Duan and Xiao-Chu Yan
    Citation: Diagnostic Pathology 2019 14:89
    Content type: Case Report Published on:

  16. Tumor-to-tumor metastasis (TTM) is a rare but well-documented phenomenon that is defined as metastasis in a histologically distinct tumor. Ovarian mature teratomas (OMTs) can coexist with various cancers by ma...

    Authors: Mitsutake Yano, Tomomi Katoh, Tetsuya Hamaguchi, Eito Kozawa, Mei Hamada, Koji Nagata and Masanori Yasuda
    Citation: Diagnostic Pathology 2019 14:88
    Content type: Case Report Published on:

  17. Following publication of the original article [1], the authors reported an added data on Table 1 in their paper. The original article [1] has been updated.

    Authors: C. Elfgen, B. Papassotiropoulos, Z. Varga, L. Moskovszky, M. Nap, U. Güth, A. Baege, E. Amann, F. Chiesa and C. Tausch
    Citation: Diagnostic Pathology 2019 14:87
    Content type: Correction Published on:

    The original article was published in Diagnostic Pathology 2019 14:58

  18. Solitary fibrous tumour (SFT) is a mesenchymal tumour of fibroblastic type, and it develops in almost any part of the human body. However, according to previous studies, the occurrence of intravascular SFTs is...

    Authors: Jingyuan Fan, Jinfeng Qiu and Qingjun Wei
    Citation: Diagnostic Pathology 2019 14:86
    Content type: Case Report Published on:

  19. At the 3rd week of human embryo, some cell clumps are formed by the hyperplasia of mesenchymal cells at the germ layer of the yolk sac wall. These cell clumps are known as blood islands. The cells in the cente...

    Authors: Jianhong An, Yufeng Zhang, Jiao Luo and Hong Shen
    Citation: Diagnostic Pathology 2019 14:85
    Content type: Case Report Published on:

  20. CRTC1-MAML2 fusion is often detected in low- or intermediate-grade salivary mucoepidermoid carcinoma (MEC), and it is associated with a favorable clinical course. Primary MEC of the liver is an extremely rare,...

    Authors: Jiro Watanabe, Keita Kai, Ken Tanikawa, Mamoru Hiraki, Naohisa Mizukami, Shinichi Aishima, Takafumi Nakano and Hidetaka Yamamoto
    Citation: Diagnostic Pathology 2019 14:84
    Content type: Case Report Published on:

  21. Atypical multinucleated stromal giant cells (MSGCs) are occasionally encountered in the esophagogastric mucosa. This study aims to investigate the origin and clinical association of MSGCs in the upper gastroin...

    Authors: Taha Sachak, Wendy L. Frankel, Christina A. Arnold and Wei Chen
    Citation: Diagnostic Pathology 2019 14:83
    Content type: Research Published on:

  22. Hydroa vacciniforme-like lymphoproliferative disorder (HV-LPD) is a cutaneous form of chronic active Epstein-Barr virus (EBV) infection, which occurs mainly in children in Latin America and Asia. It can progre...

    Authors: Na Guo, Yueqiong Chen, Yu Wang, Yuhua Huang, Yanfen Feng, Min Li and Huilan Rao
    Citation: Diagnostic Pathology 2019 14:82
    Content type: Research Published on:

  23. The poor outcome of high-grade B-cell lymphoma, with rearrangements of MYC, BCL2 and/or BCL6, also known as double-hit lymphoma or triple-hit lymphoma (DHL or THL), has been well documented, while the clinical...

    Authors: Sixia Huang, Lin Nong, Wei Wang, Li Liang, Yalin Zheng, Jumei Liu, Dong Li, Xin Li, Bo Zhang and Ting Li
    Citation: Diagnostic Pathology 2019 14:81
    Content type: Research Published on:

  24. Panniculitis-like T-cell lymphoma is an uncommon type of non-Hodgkin lymphoma, occurring usually in the form of nodules within the subcutaneous fat tissue of the extremities or trunk. In the literature, subcut...

    Authors: Jan Hrudka, Václav Eis, Josef Heřman, Zuzana Prouzová, Andreas Rosenwald and František Duška
    Citation: Diagnostic Pathology 2019 14:80
    Content type: Case Report Published on:

  25. Pseudomyogenic hemangioendothelioma (PHE)/epithelioid sarcoma-like hemangioendothelioma (ES-H) is a rare vascular tumor of intermediate malignancy that commonly occurs in soft tissue of distal extremities of y...

    Authors: Yan Ge, Xingtao Lin, Fen Zhang, Fangping Xu, Luqiao Luo, Weiye Huang, Zhihua Liu, Yanhui Liu and Zhi Li
    Citation: Diagnostic Pathology 2019 14:79
    Content type: Case Report Published on:

  26. Adenoid cystic carcinoma (ACC) is a slow growing salivary gland malignancy that is molecularly characterized by t(6:9)(q22–23;p23–24) translocations which predominantly result in MYB-NFIB gene fusions in nearly h...

    Authors: John B. McIntyre, Jenny J. Ko, Jodi Siever, Angela M. Y. Chan, Roderick H. W. Simpson, Desiree Hao and Harold Y. Lau
    Citation: Diagnostic Pathology 2019 14:78
    Content type: Research Published on:

  27. Neurofibromatosis type-1 (NF1), also called von Recklinghausen disease, is a rare genetic disease which can lead to the development of benign or even malignant tumors. NF1 is mostly diagnosed in children or ea...

    Authors: Karolina Poredska, Lumir Kunovsky, Vladimir Prochazka, Jiri Dolina, Miroslava Chovancova, Jakub Vlazny, Tomas Andrasina, Michal Eid, Petr Jabandziev, Petr Kysela and Zdenek Kala
    Citation: Diagnostic Pathology 2019 14:77
    Content type: Case Report Published on:

  28. This study aims to provide genetic diagnoses for 30 cases of fetal skeletal dysplasia, and a molecular basis for the future prenatal diagnosis of fetal skeletal dysplasia.

    Authors: Yan Liu, Li Wang, Yi-Ke Yang, Ying Liang, Tie-Juan Zhang, Na Liang, Li-Man Yang, Si-Jing Li, Dan Shan and Qing-Qing Wu
    Citation: Diagnostic Pathology 2019 14:76
    Content type: Research Published on:

  29. The bone formation within bladder tumors could be encountered in 3 conditions. These might consist of malignant bone formation in mesenchymal tumors; mixed mesenchymal and epithelial tumors; and epithelial tum...

    Authors: Joëlle Razafimahefa, Clément Gosset, Pierre Mongiat-Artus, Tsitohery Francine Andriamampionona and Jérôme Verine
    Citation: Diagnostic Pathology 2019 14:75
    Content type: Case Report Published on:

  30. To determine the relevance of the single or combination mutations of BRAF V600E, TERT, and NRAS genes and the clinicopathologic relationship in papillary thyroid cancer (PTC).

    Authors: Meiling Huang, Changjiao Yan, Jingjing Xiao, Ting Wang and Rui Ling
    Citation: Diagnostic Pathology 2019 14:74
    Content type: Research Published on:

  32. Endocervical gastric-type adenocarcinoma (GAS) is a rare non-human papillomavirus-associated adenocarcinoma (NHPVA) with morphologic and immunohistochemical features of gastric differentiation. This study aime...

    Authors: Shanshan Lu, Danhua Shen, Yun Zhao, Nan Kang and Xingxing Wang
    Citation: Diagnostic Pathology 2019 14:72
    Content type: Research Published on:

  33. Mesonephric adenocarcinoma (MNAC) is a rare tumor of the female genital tract, which originates from mesonephric duct remnants. Its diagnosis is pathologically challenging, because MNAC may exhibit a mixture o...

    Authors: Nelson Montalvo, Ligia Redrobán and David Galarza
    Citation: Diagnostic Pathology 2019 14:71
    Content type: Case Report Published on:

  35. Subjective qualitative descriptors are sometimes used to describe atypical breast lesions diagnosed on core needle biopsy (CNB) which are limited in extent. In clinical practice, this terminology is used to im...

    Authors: Gary Tozbikian, Michael George and Debra L. Zynger
    Citation: Diagnostic Pathology 2019 14:69
    Content type: Research Published on:

  36. BCL2 protein inhibitor venetoclax (ABT-199) has been authorized by Food and Drug Administration for relapsed/refractory chronic lymphoid leukemia with 17p deletion. Although venetoclax/ABT-199 also caused cell de...

    Authors: Jing-dong Zhou, Ting-juan Zhang, Zi-jun Xu, Yu Gu, Ji-chun Ma, Xi-xi Li, Hong Guo, Xiang-mei Wen, Wei Zhang, Lei Yang, Xing-hui Liu, Jiang Lin and Jun Qian
    Citation: Diagnostic Pathology 2019 14:68
    Content type: Research Published on:

  37. Primary pulmonary lymphoepithelioma-like carcinoma (LELC) is a rare tumor subtype accounting for around 0.9% of lung cancers. At present, research on LELC mainly focuses on pathological diagnosis, while the mo...

    Authors: Hong Xuan, Chai Zhengjun, Han Yang and Chen Guohan
    Citation: Diagnostic Pathology 2019 14:67
    Content type: Case Report Published on:

  39. The establishment of whole-slide imaging (WSI) as a medical diagnostic device allows that pathologists may evaluate mitotic activity with this new technology. Furthermore, the image digitalization provides an ...

    Authors: Kazuhiro Tabata, Naohiro Uraoka, Jamal Benhamida, Matthew G. Hanna, Sahussapont Joseph Sirintrapun, Brandon D. Gallas, Qi Gong, Rania G. Aly, Katsura Emoto, Kant M. Matsuda, Meera R. Hameed, David S. Klimstra and Yukako Yagi
    Citation: Diagnostic Pathology 2019 14:65
    Content type: Research Published on:

  40. Primary grade 2 neuroendocrine tumors of the cervix in female patients are rare and have a highly aggressive clinical course. This study is aimed to analyse the diagnosis, genetic changes, management and progn...

    Authors: Ran Zhu, Huanwen Wu, Bo Chen, Junyi Pang and Zhen Huo
    Citation: Diagnostic Pathology 2019 14:64
    Content type: Research Published on:

  41. Solitary fibrous tumours (SFTs) rarely occur in the orbit, especially in the lacrimal area. These tumours are mostly solid. Cystic changes have been documented, but they remain very rare. Only three cases of p...

    Authors: Ancuta-Augustina Gheorghisan-Galateanu, Dana Cristina Terzea, Iulia Burcea, Roxana Dusceac, Cristina Capatina and Catalina Poiana
    Citation: Diagnostic Pathology 2019 14:63
    Content type: Case Report Published on:

  43. Intestinal metaplasia (IM) of the gastric mucosa is classified as complete (Type I) and incomplete IM (Type II and III) subtypes, which showed significantly different risk for developing to gastric adenocarcin...

    Authors: Xiaojian Duan, Hongwei Lian, Jie Li, Benyan Wu, Weihua Wang, Tao Wu, Changzheng Wang, Yan Dou, Zhongren Zhou, Bingzhi Wang, Liyan Xue and Gangshi Wang
    Citation: Diagnostic Pathology 2019 14:61
    Content type: Research Published on:

  45. Adenosquamous carcinoma (ADSC) of the lung, a rare but aggressive subtype of non-small cell lung cancer (NSCLC), is defined as a carcinoma containing components of adenocarcinoma (ADC) and squamous cell carcin...

    Authors: Hsiang-Ling Ho, Hua-Lin Kao, Yi-Chen Yeh and Teh-Ying Chou
    Citation: Diagnostic Pathology 2019 14:59
    Content type: Research Published on:

  46. Evaluation of core needle biopsies (CNB) is a standard procedure for the diagnosis of breast cancer. However, tissue processing and image preparation is a time- consuming procedure and instant on-site availabi...

    Authors: C. Elfgen, B. Papassotiropoulos, Z. Varga, L. Moskovszky, M. Nap, U. Güth, A. Baege, E. Amann, F. Chiesa and C. Tausch
    Citation: Diagnostic Pathology 2019 14:58
    Content type: Research Published on:

    The Correction to this article has been published in Diagnostic Pathology 2019 14:87

  47. Systemic amyloidosis is a devastating group of disorders for which there is no current cure. The treatment goal is to reduce the burden of amyloidogenic protein precursors. The treatment is only effective if a...

    Authors: Ashraf El-Meanawy, Christopher Mueller and Kenneth A. Iczkowski
    Citation: Diagnostic Pathology 2019 14:57
    Content type: Short report Published on:

  48. Standard treatment with a thiotepa-based regimen in countries with a limited resource is less feasible. Aims of the study were to evaluate the treatment outcome, and identify the prognostic factors in patients...

    Authors: Pimjai Niparuck, Paisarn Boonsakan, Taksayut Sutthippingkiat, Sulada Pukiat, Pichika Chantrathammachart, Sithakom Phusanti, Kochawan Boonyawat, Teeraya Puavilai, Pantep Angchaisuksiri, Artit Ungkanont, Suporn Chuncharunee and Vichai Atichartakarn
    Citation: Diagnostic Pathology 2019 14:56
    Content type: Research Published on:

  49. Tumour-associated macrophages (TAMs) play an important role in the growth, progression, and metastasis of tumours. Epithelial-mesenchymal transition (EMT) is a mechanism for tumour invasion and metastasis. In ...

    Authors: Jihong Liu, Chunxiao Li, Liyan Zhang, Kai Liu, Xianli Jiang, Xueli Wang, Lan Yang, Weihua Liang, Kunping Liu, Jianming Hu and Feng Li
    Citation: Diagnostic Pathology 2019 14:55
    Content type: Research Published on:

  50. Endometrial mesonephric-like adenocarcinomas exhibit classical histologic features of mesonephric carcinoma; however, it remains unclear whether these tumors represent mesonephric (Wolffian) carcinoma or endom...

    Authors: Mitsutake Yano, Daisuke Shintani, Tomomi Katoh, Mei Hamada, Kozue Ito, Eito Kozawa, Kosei Hasegawa and Masanori Yasuda
    Citation: Diagnostic Pathology 2019 14:54
    Content type: Case Report Published on:
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