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  1. Content type: Case Report

    Although the primary malignant spleen tumor is relatively rare, lymphoma is the most common splenic malignancy. It can have quite different clinical manifestations that usually lead to relatively poor outcomes...

    Authors: Jing Chang, Qing Chen, Yuan Jian, Ping Wei, Guang-Zhong Yang, Ying Wang, Xiang-Yang Fang and Qian-Mei Sun

    Citation: Diagnostic Pathology 2018 13:61

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  2. Content type: Research

    In vitro studies showed that the aryl hydrocarbon receptor (AHR) contributed to the development of cutaneous squamous cell carcinomas, but supporting clinical data are lacking.

    Authors: Zhan-Yan Pan, Jia Chen, Qiong Wu, Ting-Ting Hu, Lingyi Lu and Qiang Ju

    Citation: Diagnostic Pathology 2018 13:59

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  3. Content type: Correction

    After publication of this work [1], the authors noticed that the first names and last names of all the authors were inverted. In the original manuscript, they appear on PubMed as:

    Authors: Emmanuel Rivkine, Léa Marciano, Claude Polliand, Antonio Valenti, Marianne Ziol, Christophe Poncelet and Christophe Barrat

    Citation: Diagnostic Pathology 2018 13:58

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    The original article was published in Diagnostic Pathology 2012 7:62

  4. Content type: Research

    The expression of high temperature requirement factor A1 (Htra1) has been reported to be decreased in ovarian carcinoma, but its prognostic effect remains undetermined.

    Authors: Andréanne Gagné, Bernard Têtu, Michèle Orain, Stéphane Turcotte, Marie Plante, Jean Grégoire, Marie-Claude Renaud, Isabelle Bairati and Dominique Trudel

    Citation: Diagnostic Pathology 2018 13:57

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    The Correction to this article has been published in Diagnostic Pathology 2018 13:75

  5. Content type: Research

    Myxofibrosarcoma (MFS) is one of the most common soft tissue sarcomas. Previous studies have shown that MET protein overexpressed in MFS patients and can serve as a prognostic factor. The reasons for MET prote...

    Authors: Shirong Ma, Linni Fan, Yixiong Liu, Yingmei Wang, Kangjie Yu, Lifeng Wang, Na Fang, Fang Liu, Shuangping Guo and Zhe Wang

    Citation: Diagnostic Pathology 2018 13:56

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  6. Content type: Research

    HPV 18 is one of the most prevalent oncogenic types, only second to HPV 16, and included in the licensed vaccines on the market. In this study, we describe the production and characterization of a panel of mon...

    Authors: Yao Zhang, Ye He, Ling Li, Shutian Liang, Mei Yan, Dongyan Ren, Zengmin Yang, Wenli Zhao, Luyan Miao, Haijiang Zhang and Yongjiang Liu

    Citation: Diagnostic Pathology 2018 13:55

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  7. Content type: Research

    Metanephric adenoma is a rare, benign renal neoplasm with occasional misdiagnosis. However, its molecular characterization is not fully understood.

    Authors: Ying Ding, Cong Wang, Xuejie Li, Yangyang Jiang, Ping Mei, Wenbin Huang, Guoxin Song, Jinsong Wang, Guoqiang Ping, Ran Hu, Chen Miao, Xiao He, Gang Chen, Hai Li, Yan Zhu and Zhihong Zhang

    Citation: Diagnostic Pathology 2018 13:54

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  8. Content type: Case Report

    Primary angiosarcoma of the kidney is a rare and aggressive malignant tumor presenting with a recognizable vascular differentiation. Its prognosis is fatal and the pathogenesis remains unclear. Renal angiomyol...

    Authors: Hongwei Guan, Lizhi Zhang, Qiuping Zhang, Wenjing Qi, Suling Xie, Jinping Hou and Huali Wang

    Citation: Diagnostic Pathology 2018 13:53

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  9. Content type: Research

    Intramuscular / cellular myxomas and low-grade myxofibrosarcomas are two different tumor entities with a significant histological overlap, especially if dealing with small biopsies. Despite the morphological s...

    Authors: Sandra Sunitsch, Magdalena Maria Gilg, Karl Kashofer, Franz Gollowitsch, Andreas Leithner and Bernadette Liegl-Atzwanger

    Citation: Diagnostic Pathology 2018 13:52

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  10. Content type: Case Report

    Melanotic Xp11 translocation renal cancer (TRC) is a newly described exceedingly rare tumor, and its characterization remains controversial. This study aimed to describe a case of distinctive melanotic Xp11 TR...

    Authors: Hongbiao Jing, Hong Wei, Hongtu Yuan, Yahong Li, Ning Li and Dianbin Mu

    Citation: Diagnostic Pathology 2018 13:51

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  11. Content type: Research

    Cutaneous epithelioid angiomatous nodule (CEAN) is a very rare and relatively recently recognized vascular proliferation characterized usually by minimal cytological atypia and accompanying mitotic activity. A...

    Authors: Runjan Chetty, Zaid S. Kamil, Ami Wang, Ayman Al Habeeb and Danny Ghazarian

    Citation: Diagnostic Pathology 2018 13:50

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  12. Content type: Research

    Lung adenocarcinoma with EGFR activating mutations will inevitably acquire resistance to first generation TKIs. Acquired EGFR T790M mutation causes about 50% of these resistance cases. Droplet digital PCR (ddP...

    Authors: Chenguang Li, Rui Jia, Hailin Liu, Bin Zhang and Changli Wang

    Citation: Diagnostic Pathology 2018 13:49

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  13. Content type: Research

    Basal cell adenoma (BCA) and basal cell adenocarcinoma (BCAC) are benign and malignant, basaloid salivary gland neoplasms, respectively. These tumors show a dual-cell proliferation of inner luminal/ductal cell...

    Authors: Yuzo Oyama, Haruto Nishida, Takahiro Kusaba, Hiroko Kadowaki, Motoki Arakane, Junpei Wada, Shogo Urabe, Takashi Hirano, Kenji Kawano, Masashi Suzuki, Shigeo Yokoyama and Tsutomu Daa

    Citation: Diagnostic Pathology 2018 13:48

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  14. Content type: Research

    Several anti-programmed cell death-1 (PD-1) and anti-programmed cell death ligand-1 (PD-L1) therapies have shown encouraging safety and clinical activity in a variety of tumor types. A potential role for PD-L1...

    Authors: Paul Scorer, Marietta Scott, Nicola Lawson, Marianne J. Ratcliffe, Craig Barker, Marlon C. Rebelatto and Jill Walker

    Citation: Diagnostic Pathology 2018 13:47

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  15. Content type: Case Report

    CD5-positive diffuse large B-cell lymphoma (DLBCL) and intravascular large B-cell lymphoma (IVL) are recognized as rare subsets of large B-cell lymphoma with poor prognosis. These two categories have similar c...

    Authors: Rieko Kano, Hiroaki Masaie, Akihisa Hino, Hironao Yasuoka, Shigenori Nagata, Jun Ishikawa and Shin-ichi Nakatsuka

    Citation: Diagnostic Pathology 2018 13:46

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  16. Content type: Research

    Metastasis-associated in colon cancer 1 (MACC1) has been reported to promote tumor cell invasion and metastasis. Cancer stem cells and epithelial-mesenchymal transition (EMT) have also been reported to promote...

    Authors: Bo Zhu, Yichao Wang, Xiaolin Wang, Shiwu Wu, Lei Zhou, Xiaomeng Gong, Wenqing Song and Danna Wang

    Citation: Diagnostic Pathology 2018 13:45

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  17. Content type: Research

    Salivary gland malignancies are a very heterogeneous group of cancers, with histologically > 20 different subtypes, and prognosis varies greatly. Their etiology is unknown, however, a few small studies show pr...

    Authors: Linnea Haeggblom, Ramona Gabriela Ursu, Leila Mirzaie, Tove Attoff, Caroline Gahm, Lalle Hammarstedt Nordenvall and Anders Näsman

    Citation: Diagnostic Pathology 2018 13:44

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  18. Content type: Case Report

    Ovarian serous borderline tumor/atypical proliferative serous tumor (SBT/APST) is characterized by presenting at an early stage and much longer survival than high-grade serous carcinoma. Given that the prognos...

    Authors: Chiaki Kubo, Shigenori Nagata, Takeshi Fukuda, Rieko Kano, Takaaki Tanaka, Katsuyuki Nakanishi, Masahiko Ohsawa and Shin-ichi Nakatsuka

    Citation: Diagnostic Pathology 2018 13:43

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  19. Content type: Research

    The incidence of abnormal cervical smears in the United Arab Emirates (UAE) is 3.6%. Data regarding specific high-risk HPV (hrHPV) genotypes are insufficient. Identification of hrHPV subtypes is essential to a...

    Authors: Alia Albawardi, M. Ruhul Quddus, Shamsa Al Awar and Saeeda Almarzooqi

    Citation: Diagnostic Pathology 2018 13:42

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  20. Content type: Retraction Note

    The editor has retracted this article [1] because of flaws and inconsistencies in the methodology, reporting and interpretation of the data.

    Authors: Xiaowei Zhang, Haiming Wang, Qian Li, Yunpeng Liu, Peiqing Zhao and Tao Li

    Citation: Diagnostic Pathology 2018 13:40

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    The original article was published in Diagnostic Pathology 2018 13:11

  21. Content type: Case Report

    Lymphoepithelioma-like carcinoma (LELC) is a rare entity among thyroid tumors. Based on the limited number of case reports that exist, the association of Epstein–Barr virus (EBV) with primary thyroid LELCs see...

    Authors: Chih-Yi Liu and Shih-Hung Huang

    Citation: Diagnostic Pathology 2018 13:39

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  22. Content type: Research

    The Ki-67 Labelling Index (LI) is used as an ancillary tool in glioma diagnostics. Interobserver variability has been reported and no precise guidelines are available. Nor is it known whether novel digital app...

    Authors: Ljudmilla A. G. Nielsen, Julie A. Bangsø, Kim H. Lindahl, Rikke H. Dahlrot, Jacob v. B. Hjelmborg, Steinbjørn Hansen and Bjarne W. Kristensen

    Citation: Diagnostic Pathology 2018 13:38

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  23. Content type: Case Report

    Primary central nervous system lymphoma (PCNSL) is an uncommon tumor in the brain. Although most PCNSL are readily diagnosed as diffuse large B cell lymphoma (DLBCL) on the first biopsy, very rare cases have b...

    Authors: Rodrigo Javier, Nawal Shaikh, Maciej S. Lesniak, Adam Sonabend, Roger Stupp, Amir Behdad and Craig Horbinski

    Citation: Diagnostic Pathology 2018 13:37

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  24. Content type: Research

    Nuclear forkhead box protein P1 (N-FOXP1) expression in invasive breast cancer has been documented in the literature. However, the FOXP1 expression patterns at different stages of breast cancer progression are...

    Authors: Bao-Hua Yu, Bai-Zhou Li, Xiao-Yan Zhou, Da-Ren Shi and Wen-Tao Yang

    Citation: Diagnostic Pathology 2018 13:36

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  25. Content type: Research

    The mucopolysaccharidosis type I (MPS I) is a lysosomal storage disease resulting from the defective activity of the enzyme α-L-iduronidase (IDUA). The disease has three major clinical subtypes (severe Hurler syn...

    Authors: Latifa Chkioua, Hela Boudabous, Ibtissem Jaballi, Oussama Grissa, Hadhami Ben Turkia, Neji Tebib and Sandrine Laradi

    Citation: Diagnostic Pathology 2018 13:35

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  26. Content type: Case Report

    We report the first case of composite lymphoma consisting of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), follicular lymphoma (FL) and high-grade B-cell lymphoma with MYC and BCL2 rearrangem...

    Authors: Alison M. Moore, Olga Moshkin, Gordon J. Swain, Susan Crocker and David P. LeBrun

    Citation: Diagnostic Pathology 2018 13:34

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  27. Content type: Research

    Radiotherapy is one of the most common and effective treatment methods for cancer, and improving the radiosensitivity of tumor tissues during the treatment process is vital. We report the mechanisms of glycoge...

    Authors: Jialin Ren, Tingting Liu, Yang Han, Qiongzi Wang, Yanzhi Chen, Guang Li and Lihong Jiang

    Citation: Diagnostic Pathology 2018 13:33

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  28. Content type: Case Report

    The occurrence of malignant lymphoma after delivery is an extremely rare event. Although several cases of Hodgkin lymphoma and B cell lymphoma and a few cases of peripheral T cell lymphoma (PTCL) after deliver...

    Authors: Kenichi Mizutani, Sohsuke Yamada, Xin Guo, Chizuru Futatsuya, Motona Kumagai, Akihiro Shioya, Akane Aikawa, Satoko Nakada, Nozomu Kurose, Hiroshi Minato and Takayuki Nojima

    Citation: Diagnostic Pathology 2018 13:32

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  29. Content type: Research

    Small cell carcinoma of the uterine cervix is a rare and highly malignant tumor, and its etiopathogenesis is strongly related to high-risk HPV infections.

    Authors: Peifeng Li, Jing Ma, Xiumin Zhang, Yong Guo, Yixiong Liu, Xia Li, Danhui Zhao and Zhe Wang

    Citation: Diagnostic Pathology 2018 13:31

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  30. Content type: Research

    Recent research supports a significant role of immune checkpoint inhibitors in the treatment of solid tumors. However, relevant reports for programmed death-ligand 1 (PD-L1) and CD8+ tumor-infiltrating lymphoc...

    Authors: Haiyue Wang, Zhongwu Li, Bin Dong, Wei Sun, Xin Yang, Ruping Liu, Lixin Zhou, Xiaozheng Huang, Ling Jia and Dongmei Lin

    Citation: Diagnostic Pathology 2018 13:30

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  31. Content type: Research

    Telepathology (TP) provides remote pathology services for primary diagnosis practices, including intraoperative consultation of surgical pathology; it has not been widely implemented in China. In this study, t...

    Authors: Yingxin Huang, Yan Lei, Qi Wang, Dazhou Li, Lili Ma, Lili Guo, Minshan Tang, Guanglong Liu, Qianwen Yan, Lan Shen, Guihui Tong, Zhiliang Jing, Yan Zhang and Yongjian Deng

    Citation: Diagnostic Pathology 2018 13:29

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  32. Content type: Case Report

    Epithelioid cell histiocytoma (ECH), which is also known as epithelioid benign fibrous histiocytoma, has been classified as a rare variant of fibrous histiocytoma (FH). However, the recent detection of ALK pro...

    Authors: Ryuko Nakayama, Yuki Togashi, Satoko Baba, Yo Kaku, Yuki Teramoto, Takaki Sakurai, Hironori Haga and Kengo Takeuchi

    Citation: Diagnostic Pathology 2018 13:28

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  33. Content type: Case Report

    The diagnosis of granulomatous amoebic encephalitis is challenging for clinicians because it is a rare and lethal disease. Previous reports have indicated that Acanthamoeba with some specific genotypes tend to ca...

    Authors: Takahiro Matsui, Tetsuo Maeda, Shinsuke Kusakabe, Hideyuki Arita, Kenji Yagita, Eiichi Morii and Yuzuru Kanakura

    Citation: Diagnostic Pathology 2018 13:27

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  34. Content type: Retraction Note

    The editor has retracted this article [1] because it shows significant overlap with the following articles (amongst others) [2, 3]. None of the authors responded to correspondence regarding this retraction.

    Authors: Huifen Li, Weihua Huang and Rongcheng Luo

    Citation: Diagnostic Pathology 2018 13:26

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    The original article was published in Diagnostic Pathology 2015 10:117

  35. Content type: Research

    The translocation t(14;18)(q32;q21) is the genetic hallmark of follicular lymphoma (FL) and can be observed in 85–90% of cases. Whether the translocation is restricted to cells with germinal center B-cell phen...

    Authors: Perikles Kosmidis, Barbara Mankel, Falko Fend and Patrick Adam

    Citation: Diagnostic Pathology 2018 13:25

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  36. Content type: Case Report

    Although p53 signature, benign-appearing epithelial cells with p53 diffuse expression, is frequently found in the fallopian tubes, the clinical and pathological significance of this lesion in the case of high-...

    Authors: Yuichiro Hatano, Shinya Fukuda, Hiroshi Makino, Hiroyuki Tomita, Ken-ichirou Morishige and Akira Hara

    Citation: Diagnostic Pathology 2018 13:24

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  37. Content type: Research

    Hepatic steatosis renders hepatocytes vulnerable to injury, resulting in the progression of preexisting liver disease. Previous animal and cell culture studies implicated mammalian target of rapamycin (mTOR), ...

    Authors: Euno Choi, Won Kim, Sae Kyung Joo, Sunyoung Park, Jeong Hwan Park, Yun Kyung Kang, So-Young Jin and Mee Soo Chang

    Citation: Diagnostic Pathology 2018 13:23

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  38. Content type: Research

    The G protein-coupled bile acid receptor (TGR5) is a cell surface receptor which induces the production of intracellular cAMP and promotes epithelial-mesenchymal transition in gastric cancer cell lines. TGR5 i...

    Authors: Chaohui Lisa Zhao, Ali Amin, Yiang Hui, Dongfang Yang and Weibiao Cao

    Citation: Diagnostic Pathology 2018 13:22

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  39. Content type: Research

    Tumour budding (TB) and Tumour Stroma Ratio (TSR) may be rewarding in the treatment stratification of patients with stage II colon cancer. However, lack of standardization may exclude these parameters from bei...

    Authors: Ann C. Eriksen, Johnnie B. Andersen, Jan Lindebjerg, René dePont Christensen, Torben F. Hansen, Sanne Kjær-Frifeldt and Flemming B. Sørensen

    Citation: Diagnostic Pathology 2018 13:20

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  40. Content type: Research

    Detection of HER2/neu receptor overexpression and/or amplification is a prerequisite for efficient anti-HER2 treatment of breast and gastric carcinomas. Immunohistochemistry (IHC) of the HER2 protein is the mo...

    Authors: Andreas H. Scheel, Frédérique Penault-Llorca, Wedad Hanna, Gustavo Baretton, Peter Middel, Judith Burchhardt, Manfred Hofmann, Bharat Jasani and Josef Rüschoff

    Citation: Diagnostic Pathology 2018 13:19

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  41. Content type: Case Report

    Ischemic fasciitis is a distinctive pseudosarcomatous entity with a marked predilection for elderly and physically debilitated or immobilized patients. The etiology of these lesions is unknown but felt to be r...

    Authors: Taha Sachak, Nyla A. Heerema, Joel Mayerson, Jason E. Payne, Anil Parwani and O. Hans Iwenofu

    Citation: Diagnostic Pathology 2018 13:18

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  42. Content type: Research

    The clinicopathological features and Epstein-Barr virus (EBV) infection status of lymphoma in children and adolescents in South China is under-researched. South China is a well-known high-incidence area of EBV...

    Authors: Changfei Qin, Yuhua Huang, Yanfen Feng, Min Li, Na Guo and Huilan Rao

    Citation: Diagnostic Pathology 2018 13:17

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  43. Content type: Case Report

    Plasma cell myeloma (PCM) is a neoplasm of terminally differentiated B lymphocytes with molecular heterogeneity. Although therapy-related myeloid neoplasms are common in plasma cell myeloma patients after chem...

    Authors: Jonathon H. Gralewski, Ginell R. Post, Frits van Rhee and Youzhong Yuan

    Citation: Diagnostic Pathology 2018 13:15

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  44. Content type: Case Report

    Mast cell leukemia (MCL) is a very rare form of systemic mastocytosis (SM) and accounts for less than 0.5% of all mastocytosis. The diagnosis of MCL requires the presence of SM criteria, accompanied by leukemi...

    Authors: Yalin Zheng, Lin Nong, Li Liang, Wei Wang and Ting Li

    Citation: Diagnostic Pathology 2018 13:14

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  45. Content type: Research

    The DecisionDx-Melanoma test provides prognostic information for patients with cutaneous melanoma (CM). Using formalin-fixed paraffin-embedded primary tumor tissue, the RT-PCR-based test classifies patients in...

    Authors: Robert W. Cook, Brooke Middlebrook, Jeff Wilkinson, Kyle R. Covington, Kristen Oelschlager, Federico A. Monzon and John F. Stone

    Citation: Diagnostic Pathology 2018 13:13

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  46. Content type: Review

    The programmed death receptor 1 (PD-1) protein is a cell-surface receptor on certain lymphocytes that, with its ligand programmed death ligand 1 (PD-L1), helps to down-regulate immune responses. Many cancer ty...

    Authors: Margarita Udall, Maria Rizzo, Juliet Kenny, Jim Doherty, SueAnn Dahm, Paul Robbins and Eric Faulkner

    Citation: Diagnostic Pathology 2018 13:12

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  47. Content type: Research

    Several studies have suggested that claudin proteins, which are the main components of tight junction structures, are related to the regulation of cell polarity and cell differentiation.

    Authors: Xiaowei Zhang, Haiming Wang, Qian Li, Yunpeng Liu, Peiqing Zhao and Tao Li

    Citation: Diagnostic Pathology 2018 13:11

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    The Retraction Note to this article has been published in Diagnostic Pathology 2018 13:40

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