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  1. Content type: Review

    Oral squamous cell carcinoma (OSCC) accounts over 90% of malignant neoplasms of the oral cavity. This pathological entity is associated to a high mortality rate that has remained unchanged over the past decade...

    Authors: Maria Noel Marzano Rodrigues Petruzzi, Karen Cherubini, Fernanda Gonçalves Salum and Maria Antonia Zancanaro de Figueiredo

    Citation: Diagnostic Pathology 2017 12:32

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  2. Content type: Research

    Histopathological diagnosis is important for prognostication and choice of treatment in patients with cancer in the lung. Metastases to the lungs are common and need to be distinguished from primary lung cance...

    Authors: Kajsa Ericson-Lindquist, Anna Johansson, Per Levéen, Göran Elmberger, Göran Jönsson, Johan Staaf and Hans Brunnström

    Citation: Diagnostic Pathology 2017 12:31

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  3. Content type: Case Report

    Imaging and histology of clear-cell ependymoma and cerebellum-based hemangioblastoma are similar; distinguishing between them is a diagnostic challenge.

    Authors: Xiu-Peng Zhang, Yang Liu, Di Zhang, Qin Zheng, Chen Wang, Liang Wang, Qing-Chang Li, Xue-Shan Qiu and En-Hua Wang

    Citation: Diagnostic Pathology 2017 12:28

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  4. Content type: Case Report

    Malignant gastrointestinal neuroectodermal tumor (GNET) is an extremely rare entity that was first described by Zambrano et al. in 2003 as “Clear cell sarcoma-like tumor of the gastrointestinal tract”. It shar...

    Authors: Mohammed J. Alyousef, Jumana A. Alratroot, Tarek ElSharkawy, Mohamed A. Shawarby, Mohammad A. Al hamad, Tarek M. Hashem and Ahmed Alsayyah

    Citation: Diagnostic Pathology 2017 12:29

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  5. Content type: Research

    Recently, cytology has been applied to the diagnosis of oral lesions. We aimed to explore the diagnostic accuracy of oral cytology based on the histological diagnosis.

    Authors: Joji Sekine, Eiji Nakatani, Katsumi Hideshima, Teruaki Iwahashi and Hiroshi Sasaki

    Citation: Diagnostic Pathology 2017 12:27

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  6. Content type: Research

    Idiopathic pulmonary arterial hypertension (IPAH) is a rare, fatal disease of unknown pathogenesis. Evidence from our recent study suggests that IPAH pathogenesis is related to upregulation of the Wnt/planar c...

    Authors: Shun Yanai, Megumi Wakayama, Haruo Nakayama, Minoru Shinozaki, Hisayuki Tsukuma, Naobumi Tochigi, Tetsuo Nemoto, Tsutomu Saji and Kazutoshi Shibuya

    Citation: Diagnostic Pathology 2017 12:25

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  7. Content type: Case Report

    Uterine sarcoma is a rare tumor that is often difficult to classify based on morphological and immunohistochemical analysis alone. Limited access to molecular biological analysis in routine practice would hind...

    Authors: Terufumi Kubo, Shintaro Sugita, Ryuichi Wada, Noriaki Kikuchi, Masahiro Iwasaki, Yumika Ito, Taro Sugawara, Hiromi Fujita, Makoto Emori, Ryoichi Tanaka, Hiroshi Hirano, Tsuyoshi Saito and Tadashi Hasegawa

    Citation: Diagnostic Pathology 2017 12:26

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  8. Content type: Research

    Recurrence and metastasis are the usual manifestations of treatment failure of epithelial ovarian carcinoma (EOC). Vasculogenic mimicry (VM; blood supply development often seen in highly aggressive cancers), a...

    Authors: Lan Yu, Bo Zhu, Shiwu Wu, Lei Zhou, Wenqing Song, Xiaomeng Gong and Danna Wang

    Citation: Diagnostic Pathology 2017 12:23

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  9. Content type: Erratum

    Authors: Alethéa Guimarães Faria, Fernando Augusto Lima Marson, Carla Cristina de Souza Gomez, Maria Ângela Gonçalves de Oliveira Ribeiro, Lucas Brioschi Morais, Maria de Fátima Servidoni, Carmen Sílvia Bertuzzo, Eulália Sakano, Maura Goto, Ilma Aparecida Paschoal, Mônica Corso Pereira, Gabriel Hessel, Carlos Emílio Levy, Adyléia Aparecida Dalbo Contrera Toro, Andressa Oliveira Peixoto, Maria Cristina Ribeiro Simões…

    Citation: Diagnostic Pathology 2017 12:22

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    The original article was published in Diagnostic Pathology 2016 11:103

  10. Content type: Research

    A tracheobronchial lesion observed during an endoscopic examination is usually sampled by the pulmonologist and sent to the pathologist for microscopic examination. Adipocytes may be observed in the lamina pro...

    Authors: Nicolas Piton, Émilie Angot, Florent Marguet and Jean-Christophe Sabourin

    Citation: Diagnostic Pathology 2017 12:21

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  11. Content type: Research

    Studies have partly demonstrated the clinical validity of Ki-67 as a predictive marker in the neoadjuvant setting, but the question of the best cut-off points as well as the importance of this marker as a prog...

    Authors: Balázs Ács, Veronika Zámbó, Laura Vízkeleti, A. Marcell Szász, Lilla Madaras, Gyöngyvér Szentmártoni, Tímea Tőkés, Béla Á. Molnár, István Artúr Molnár, Stefan Vári-Kakas, Janina Kulka and Anna-Mária Tőkés

    Citation: Diagnostic Pathology 2017 12:20

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  12. Content type: Research

    The analysis of fresh frozen muscle specimens is standard following routine muscle biopsy, but this service is not widely available in countries with limited medical facilities, such as Thailand. Nevertheless,...

    Authors: Chinnawut Suriyonplengsaeng, Charungthai Dejthevaporn, Chaiyos Khongkhatithum, Suda Sanpapant, Nattha Tubthong, Koset Pinpradap, Nippa Srinark and Jariya Waisayarat

    Citation: Diagnostic Pathology 2017 12:19

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  13. Content type: Research

    High risk human papillomavirus (HR HPV) infects cells at the squamocolumnar junction (SCJ) of the cervix, causing cancer. Cytokeratin (CK)7 is an SCJ marker, and stains cervical neoplasia. CK19 is a binding pa...

    Authors: Hojung Lee, Hyekyung Lee and Yong Kyun Cho

    Citation: Diagnostic Pathology 2017 12:18

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    The Erratum to this article has been published in Diagnostic Pathology 2017 12:40

  14. Content type: Research

    Cellular angiofibroma is a rare benign mesenchymal neoplasm with morphological and immunohistochemical similarities to spindle cell lipoma. Karyotypic information on cellular angiofibroma is restricted to one ...

    Authors: Ioannis Panagopoulos, Ludmila Gorunova, Bodil Bjerkehagen, Kristin Andersen, Marius Lund-Iversen and Sverre Heim

    Citation: Diagnostic Pathology 2017 12:17

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  15. Content type: Research

    Genomic instability caused by mutation of the checkpoint molecule TP53 may endow cancer cells with the ability to undergo genomic evolution to survive stress and treatment. We attempted to gain insight into the p...

    Authors: Meiying Zhang, Guanglei Zhuang, Xiangjun Sun, Yanying Shen, Wenjing Wang, Qing Li and Wen Di

    Citation: Diagnostic Pathology 2017 12:16

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  16. Content type: Case Report

    Epstein-Barr virus (EBV) is associated with B-cell lymphoma in various conditions, such as immunodeficiency and chronic inflammation. We report an unusual case of EBV-positive diffuse large B-cell lymphoma (DL...

    Authors: Shin-ichi Nakatsuka, Chikao Yutani, Masako Kurashige, Masaharu Kohara, Teruaki Nagano, Takayoshi Goto, Hiroyuki Takatsuka, Hidetaka Ifuku and Eiichi Morii

    Citation: Diagnostic Pathology 2017 12:15

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  17. Content type: Research

    SESN2 plays important roles in the regulation of cell survival, cell protection, and tumor suppression. However, the relationship between SESN2 expression and the clinicopathological attributes of hepatocellul...

    Authors: Shaosen Chen, Weigang Yan, Weiya Lang, Jing Yu, Li Xu, Xinyu Xu, Yunlong Liu and Hongguang Bao

    Citation: Diagnostic Pathology 2017 12:13

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  18. Content type: Case Report

    Anastomosing hemangioma (AH) is a very rare vascular tumor mimicking angiosarcoma, predominately observed in kidney and less frequently in other organs. We present two new renal cases of AH at opposite ends of...

    Authors: Marina Perdiki, Galateia Datseri, George Liapis, Nikolaos Chondros, Ioannis Anastasiou, Maria Tzardi, Johanna K. Delladetsima and Elias Drakos

    Citation: Diagnostic Pathology 2017 12:14

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  19. Content type: Case Report

    Epithelioid schwannoma as a rare variant poses a challenge to all pathologists, as this uncommon entity is extremely difficult to conclusively diagnose by morphological analyses on a resected sample alone owin...

    Authors: Sohsuke Yamada, Mari Kirishima, Tsubasa Hiraki, Michiyo Higashi, Kazuhito Hatanaka and Akihide Tanimoto

    Citation: Diagnostic Pathology 2017 12:11

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  20. Content type: Case Report

    Combined thymic carcinoma is a malignant neoplasm of the thymus recently added to the 4th edition of the World Health Organization (WHO) classification of tumors of the lung, pleura, thymus and heart. It invol...

    Authors: Yufeng Jiang, Yang Liu, Xiuying Shi, Xiaoyun Mao, Yang Zhao and Chuifeng Fan

    Citation: Diagnostic Pathology 2017 12:9

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  21. Content type: Research

    Colorectal cancer is the major cause of cancer mortality, despite development of therapeutic strategies. The novel marker tumor necrosis factor receptor-associated protein 1 (TRAP1) is a mitochondrial heat sho...

    Authors: Min Gyoung Pak, Hyong Jong Koh and Mee Sook Roh

    Citation: Diagnostic Pathology 2017 12:6

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  22. Content type: Case Report

    Giant cell ependymoma of the filum terminale is a rare variant, generally manifested as a well-circunscribed intradural mass with an indolent biological behavior.

    Authors: Fernando Candanedo-Gonzalez, Cindy Sharon Ortiz-Arce, Samuel Rosales-Perez, Ana Lilia Remirez-Castellanos, Candelaria Cordova-Uscanga and Armando Gamboa-Dominguez

    Citation: Diagnostic Pathology 2017 12:7

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  23. Content type: Research

    Despite new treatment options for hepatocellular carcinomas (HCC) recently, 5-year survival remains poor, ranging from 50 to 70%, which may attribute to the lack of early diagnostic biomarkers. Thus, developin...

    Authors: Feifei Wang, Ruliang Wang, Qiuwen Li, Xueling Qu, Yixin Hao, Jingwen Yang, Huixia Zhao, Qian Wang, Guanghui Li, Fengyun Zhang, He Zhang, Xuan Zhou, Xioumei Peng, Yang Bian and Wenhua Xiao

    Citation: Diagnostic Pathology 2017 12:4

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  24. Content type: Research

    Double-hit lymphomas (DHL) are rare high-grade neoplasms characterized by two translocations: one involving the gene MYC and another involving genes BCL2 or BCL6, whose diagnosis depends on cytogenetic examinatio...

    Authors: Cristiano Claudino Oliveira, Helena Maciel-Guerra, Luan Kucko, Eric Jun Hirama, Américo Delgado Brilhante, Francisco Carlos Quevedo, Isabela Werneck da Cunha, Fernando Augusto Soares, Ligia Niero-Melo, Patrícia Pintor dos Reis and Maria Aparecida Custodio Domingues

    Citation: Diagnostic Pathology 2017 12:3

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  25. Content type: Research

    The Cks1 protein is an essential factor in regulating cell cycle by mediating the ubiquitination of CDK inhibitor p27kip1. It has been reported that aberrant expression of Cks1 and p27kip1 proteins was found in v...

    Authors: Lina Xu, Songqing Fan, Jin Zhao, Peng Zhou, Shuzhou Chu, Jiadi Luo, Qiuyuan Wen, Lingjiao Chen, Sailan Wen, Li Wang and Lei Shi

    Citation: Diagnostic Pathology 2017 12:2

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  26. Content type: Case Report

    Haploinsufficiency of the GATA6 transcription factor gene was recently found to be the most common cause of pancreatic agenesis, a rare cause of neonatal diabetes mellitus. Although most cases are de novo, we des...

    Authors: Daphne Yau, Elisa De Franco, Sarah E. Flanagan, Sian Ellard, Miriam Blumenkrantz and John J. Mitchell

    Citation: Diagnostic Pathology 2017 12:1

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  27. Content type: Case Report

    Diffuse large B-cell lymphoma (DLBCL) typically leads to effacement of the nodal architecture by an infiltrate of malignant cells. Rarely (<1%), DLBCL can present with an interfollicular pattern (DLBCL-IF) pre...

    Authors: Joseph Hatem, April M. Schrank-Hacker, Christopher D. Watt, Jennifer J. D. Morrissette, Adam I. Rubin, Ellen J. Kim, Sunita D. Nasta, Mariusz A. Wasik and Agata M. Bogusz

    Citation: Diagnostic Pathology 2016 11:137

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  28. Content type: Research

    The origin and heterogeneity of hepatic progenitor cells (HPCs) remain unclear. This study aimed to investigate the involvement of epithelial-mesenchymal transition (EMT) in the histogenesis of HPCs.

    Authors: Wei Xu, Nong-Rong Wang, Hua-Feng Wang, Qiong Feng, Jun Deng, Zhi-Qiang Gong, Jian Sun, Xiao-Liang Lou, Xue-Feng Yu, Lv Zhou, Jin-Ping Hu, Xiao-Feng Huang, Xiao-Qing Qi, Yan-Juan Deng, Rui Gong, Yan Guo…

    Citation: Diagnostic Pathology 2016 11:136

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  29. Content type: Research

    Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) has high short-term mortality with unknown causes. To predict this malignant condition in clinics is challenging. In this study, we aim to demonstra...

    Authors: Haiyan Min, Shanshan Fan, Shiyu Song, Yi Zhuang, Hui Li, Yongzheng Wu, Hourong Cai, Long Yi, Jinghong Dai and Qian Gao

    Citation: Diagnostic Pathology 2016 11:135

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  30. Content type: Case Report

    Calcifying epithelial odontogenic tumor (CEOT) is a rare benign neoplasia, locally aggressive, that tends to invade bone and adjacent soft tissues. This case report describes the thirteenth known case of CEOT ...

    Authors: Cristina Munteanu, Daniel Pirici, Alex Emilian Stepan, Adrian Camen and Claudiu Margaritescu

    Citation: Diagnostic Pathology 2016 11:134

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  31. Content type: Case Report

    Inhibition of the oncogenic fusion-gene EML4-ALK is a current first-line approach for patients with stage IV non-small cell lung cancer. While FISH was established as the gold standard for identifying these pa...

    Authors: Anna-Lena Volckmar, Volker Endris, Farastuk Bozorgmehr, Clemens Lier, Carlota Porcel, Martina Kirchner, Jonas Leichsenring, Roland Penzel, Michael Thomas, Peter Schirmacher, Arne Warth and Albrecht Stenzinger

    Citation: Diagnostic Pathology 2016 11:133

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  32. Content type: Research

    Signet ring cells (SRCs) often accompany gastrointestinal carcinoma, referred to as SRC carcinoma; however, breast cancers containing SRCs have not been well characterized, leaving the prognostic significance ...

    Authors: Ryuji Ohashi, Ayako Hayama, Keiko Yanagihara, Koji Yamashita, Takashi Sakatani, Hiroyuki Takei and Zenya Naito

    Citation: Diagnostic Pathology 2016 11:131

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  33. Content type: Case Report

    Inflammatory myofibroblastic tumor (IMT) is a rare low-grade malignant neoplasm with a predilection for children and young adults, and typically arises in the lung, abdominopelvic region, and retroperitoneum. ...

    Authors: Yoko Tateishi, Koji Okudela, Shigeo Kawai, Takehisa Suzuki, Shigeaki Umeda, Mai Matsumura, Mitomu Kioi and Kenichi Ohashi

    Citation: Diagnostic Pathology 2016 11:132

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  34. Content type: Case Report

    Uterine serous endometrial intraepithelial carcinoma (SEIC) is an immediate precursor of invasive carcinoma. The majority of stage IA SEICs are curable, but those with latent peritoneal metastasis and/or capil...

    Authors: Mitsuko Furuya, Teiko Sato, Reiko Tanaka, Masafumi Yamamoto, Naho Ruiz Yokota and Etsuko Miyagi

    Citation: Diagnostic Pathology 2016 11:130

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  35. Content type: Research

    As the World Health Organization grading system for gastroenteropancreatic-neuroendocrine tumors (GEP-NETs) may not always correlate with tumor progression, it is imperative that other independent predictors o...

    Authors: Yoichiro Okubo, Osamu Motohashi, Norisuke Nakayama, Ken Nishimura, Rika Kasajima, Yohei Miyagi, Manabu Shiozawa, Emi Yoshioka, Masaki Suzuki, Kota Washimi, Kae Kawachi, Madoka Nito, Yoichi Kameda and Tomoyuki Yokose

    Citation: Diagnostic Pathology 2016 11:128

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  36. Content type: Retraction Note

    Authors: Ehsan Hosseini, Behnam Pedram, Ali Mohammad Bahrami, Mohammad Hossein Jaberi Moghaddam, Javad Javanbakht, Fatemeh Emami Ghomi, Najme Jaberi Moghaddam, Mobin Koohestani and Radmehr Shafiee

    Citation: Diagnostic Pathology 2016 11:106

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    The original article was published in Diagnostic Pathology 2014 9:9

  37. Content type: Retraction Note

    Authors: Alireza Nasoori, Behnam Pedram, Zahra Kamyabi-Moghaddam, Aram Mokarizadeh, Hamid Pirasteh, Amir Farshid Fayyaz and Mohammad Barat Shooshtari

    Citation: Diagnostic Pathology 2016 11:123

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    The original article was published in Diagnostic Pathology 2015 10:23

  38. Content type: Retraction Note

    Authors: Rahim Hobbenaghi, Javad Javanbakht, Ehan Hosseini, Shahin Mohammadi, Mojtaba Rajabian, Pedram Moayeri and Mehdi Aghamohammad Hassan

    Citation: Diagnostic Pathology 2016 11:109

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    The original article was published in Diagnostic Pathology 2013 8:123

  39. Content type: Retraction Note

    Authors: Rahim Hobbenaghi, Pariya Mahboob, Siamak Saifzadeh, Javad Javanbakht, Javad Yaghoobi Yeganeh Manesh, Rasool Mortezaee, Seyed Rashid Touni, Ehsan Hosseini, Shahin Aghajanshakeri, Milad Moloudizargari and Soheil Javaherypour

    Citation: Diagnostic Pathology 2016 11:124

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    The original article was published in Diagnostic Pathology 2014 9:59

  40. Content type: Retraction Note

    Authors: Fardin Barati, Javad Javanbakht, Farajollah Adib-Hashemi, Ehsan Hosseini, Reyhaneh Safaeie, Mojtaba Rajabian, Mostafa Razmjoo, Reza Sedaghat and Mehdi Aghamohammad Hassan

    Citation: Diagnostic Pathology 2016 11:117

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    The original article was published in Diagnostic Pathology 2013 8:826

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