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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. As there is no optimal treatment of non small cell lung cancer due to its resistance to common chemotherapeutics, we investigated the effect of human placenta-conditioned medium on tumor tissue. The human plac...

    Authors: Sebastian Marwitz, Tobias Zeiser, Holger Schultz, Daniel Kähler, Mahdi Abdullah, Hans-Peter Hauber, Peter Zabel, Ekkehard Vollmer and Torsten Goldmann
    Citation: Diagnostic Pathology 2009 4:27
    Content type: Hypothesis Published on:

  2. Low and high-grade ductal carcinoma in-situ (DCIS) are known to be highly disparate by a multitude of parameters, including progression potential, immunophenotype, gene expression profile and DNA ploidy. In th...

    Authors: Oluwole Fadare, Nathan F Clement and Mohiedean Ghofrani
    Citation: Diagnostic Pathology 2009 4:26
    Content type: Research Published on:

  3. Ovarian leiomyoma is a rare benign tumor that accounts for 0.5 to 1% of all benign ovarian tumors. It probably arises from smooth muscle cells in the ovarian hilar blood vessels but there are other possible or...

    Authors: Davor Tomas, Tanja Leniček, Neven Tučkar, Zvonimir Puljiz, Mario Ledinsky and Božo Krušlin
    Citation: Diagnostic Pathology 2009 4:25
    Content type: Case Report Published on:

  4. Melanosis refers to abnormal or excessive deposition of melanin pigment in the cells and/or tissue, which can be seen in any organ but commonly in skin and oral mucosa. Melanosis of the urinary bladder is an e...

    Authors: Bo Jin, Syed Y Zaidi, Melvin Hollowell, Christopher Hollowell and Husain Saleh
    Citation: Diagnostic Pathology 2009 4:24
    Content type: Case Report Published on:

  5. Anti-neutrophil cytoplasmic antibodies (ANCA) is autoantibodies characteristic of vasculitis diseases. A connection between ANCA and Wegener's granulomatosis was well established. The interaction of both ANCA ...

    Authors: Akiko Uehara, Tadasu Sato, Atsushi Iwashiro and Sou Yokota
    Citation: Diagnostic Pathology 2009 4:23
    Content type: Research Published on:

  6. To evaluate the usefulness of this biomarker in the diagnosis of cases of cervical neoplasia we studied the immunohistochemical expression of p16INK4a in a large series of archival cervical biopsies arranged into...

    Authors: Iana Lesnikova, Marianne Lidang, Stephen Hamilton-Dutoit and Jørn Koch
    Citation: Diagnostic Pathology 2009 4:22
    Content type: Research Published on:

  8. Because of the poor sensitivity of urinary cytological findings for the diagnosis of especially low grade urinary bladder carcinoma, new molecular diagnostic methods have been proposed. We decided to verify th...

    Authors: Isin Soyuer, Mustafa Sofikerim, Fatma Tokat, Serdar Soyuer and Figen Ozturk
    Citation: Diagnostic Pathology 2009 4:20
    Content type: Research Published on:

  10. Adenoid cystic carcinomas are rare tumors with an indolent clinical course, but frequent local relapses. The identification of tumors with a higher relapse risk seems to be interesting. Hence we investigated p...

    Authors: Hans-Ullrich Völker, Matthias Scheich, Annette Berndt, Imme Haubitz, Alexandra Metzger, Hans-Konrad Müller-Hermelink, Ulrike Kämmerer and Melanie Schmidt
    Citation: Diagnostic Pathology 2009 4:18
    Content type: Research Published on:

  11. Malignant transformation of mature cystic teratoma is a rare complication. While any of the constituent tissues of a teratoma has the potential to undergo malignant transformation, squamous cell carcinoma is t...

    Authors: Henry B Armah, Anil V Parwani and Aleksandr M Perepletchikov
    Citation: Diagnostic Pathology 2009 4:17
    Content type: Case Report Published on:

  13. The recently recognized renal cell carcinomas (RCCs) associated with Xp11.2 translocations (TFE3 transcription factor gene fusions) are rare tumors predominantly reported in children. They comprise at least on...

    Authors: Henry B Armah, Anil V Parwani, Urvashi Surti and Sheldon I Bastacky
    Citation: Diagnostic Pathology 2009 4:15
    Content type: Case Report Published on:

  16. Pattern recognition receptors are a key component of the first line host defense against infection, recognizing specific microbial products. We hypothesize that monocyte hyporesponsiveness in human sepsis is a...

    Authors: Bernhard Schaaf, Karen Luitjens, Torsten Goldmann, Tobias van Bremen, Friedhelm Sayk, Christoph Dodt, Klaus Dalhoff and Daniel Droemann
    Citation: Diagnostic Pathology 2009 4:12
    Content type: Research Published on:

  17. Primary non-Hodgkin lymphoma (NHL) of the breast represents 0.04–0.5% of malignant lesions of the breast and accounts for 1.7–2.2% of extra-nodal NHL. Most primary cases are of B-cell phenotype and only rare c...

    Authors: Mona RY Bishara, Cathy Ross and Monalisa Sur
    Citation: Diagnostic Pathology 2009 4:11
    Content type: Case Report Published on:

  18. Management of endometrial precancerous lesions has been of much debate due to inconsistencies in their classification, natural history and histologic diagnosis. Endometrial hyperplasia constitutes a wide range...

    Authors: Narges Izadi-Mood, Maryam Yarmohammadi, Seyed Ali Ahmadi, Guity Irvanloo, Hayedeh Haeri, Ali Pasha Meysamie and Mahmood Khaniki
    Citation: Diagnostic Pathology 2009 4:10
    Content type: Research Published on:

  19. The reliability of gene expression profiling-based technologies to detect transcriptional differences representative of the original samples is affected by the quality of the extracted RNA. It strictly depends...

    Authors: Jai Prakash Muyal, Vandana Muyal, Brajesh Pratap Kaistha, Carola Seifart and Heinz Fehrenbach
    Citation: Diagnostic Pathology 2009 4:9
    Content type: Methodology Published on:

  20. Surfactant Protein-A (SP-A) is the most prominent among four proteins in the pulmonary surfactant-system. SP-A is expressed by alveolar epithelial cells type II as well as by a portion of non small cell lung c...

    Authors: Torsten Goldmann, Daniel Kähler, Holger Schultz, Mahdi Abdullah, Dagmar S Lang, Florian Stellmacher and Ekkehard Vollmer
    Citation: Diagnostic Pathology 2009 4:8
    Content type: Review Published on:

  21. Clear cell renal cell carcinomas (ccRCCs) constitute the most common renal carcinomas, characterized by a relatively aggressive clinical course. Thus, scientific research is targeting towards the identificatio...

    Authors: Vassilis Samaras, Maria Tsopanomichalou, Angeliki Stamatelli, Christos Arnaoutoglou, Efstathios Samaras, Marianthi Arnaoutoglou, Hercules Poulias and Calypso Barbatis
    Citation: Diagnostic Pathology 2009 4:7
    Content type: Research Published on:

  22. A general theory of sampling and its application in tissue based diagnosis is presented. Sampling is defined as extraction of information from certain limited spaces and its transformation into a statement or ...

    Authors: Klaus Kayser, Holger Schultz, Torsten Goldmann, Jürgen Görtler, Gian Kayser and Ekkehard Vollmer
    Citation: Diagnostic Pathology 2009 4:6
    Content type: Research Published on:

  24. Chronic Renal Allograft Dysfunction (CRAD) is responsible for a large number of graft failures. We have abrogated acute T-cell rejections using Ahmedabad Tolerance Induction Protocol (ATIP) with hematopoietic ...

    Authors: Rashmi D Patel, Aruna V Vanikar, Feroz A Aziz, Pankaj R Shah and Hargovind L Trivedi
    Citation: Diagnostic Pathology 2009 4:4
    Content type: Study protocol Published on:

  25. The virtual microscopy is widely accepted in Pathology for educational purposes and teleconsultation but is far from the routine use in surgical pathology due to the technical requirements and some limitations...

    Authors: Stephan Wienert, Michael Beil, Kai Saeger, Peter Hufnagl and Thomas Schrader
    Citation: Diagnostic Pathology 2009 4:3
    Content type: Software Published on:

  26. A 29-year-old woman presented with a breast tumor with a primary diagnosis of MALT lymphoma. A repeat biopsy revealed a hematological neoplasm with diffuse, Indian file, and targetoid patterns. The cells were ...

    Authors: Teresa A Vela-Chávez, Myrna D Arrecillas-Zamora, L Yolanda Quintero-Cuadra and Falko Fend
    Citation: Diagnostic Pathology 2009 4:2
    Content type: Case Report Published on:

  27. It has been more than 50 years since antinuclear antibodies were first discovered and found to be associated with connective tissue diseases. Since then different methods have been described and used for their...

    Authors: Yashwant Kumar, Alka Bhatia and Ranjana Walker Minz
    Citation: Diagnostic Pathology 2009 4:1
    Content type: Review Published on:

  28. Light emitting diodes (LED), which are available as small monochromatic light sources with characteristic features such as maximum illumination power combined with minimum energy consumption and extremely long...

    Authors: Dagmar S Lang, Tobias Zeiser, Holger Schultz, Florian Stellmacher, Ekkehard Vollmer, Peter Zabel and Torsten Goldmann
    Citation: Diagnostic Pathology 2008 3:49
    Content type: Short report Published on:

  30. Pilomatrix carcinoma is the rare malignant counterpart of pilomatrixoma, a skin adnexal tumour originating from hair matrix cells. Pilomatrix carcinoma can arise as a solitary lesion de novo, or through transform...

    Authors: Noel J Aherne, David A Fitzpatrick, David Gibbons and John G Armstrong
    Citation: Diagnostic Pathology 2008 3:47
    Content type: Case Report Published on:

  31. The chance of an intrathyroidal occurrence of a parathyroid gland is about 1–3%. Among the causes of hyperparathyroidism, parathyroid cases occur in less than 1% of patients. Here we present the case of a 63 y...

    Authors: Labiba Temmim, Fred Sinowatz, Wiam I Hussein, Osama Al-Sanea and Hady El-Khodary
    Citation: Diagnostic Pathology 2008 3:46
    Content type: Case Report Published on:

  32. Head and neck cancer including oral cancer is considered to develop by accumulated genetic alterations and the major pathway is cancerization from lesions such as intraepithelial dysplasia in oral leukoplakia ...

    Authors: Ali A Shamaa, Manal M Zyada, Mathias Wagner, Sally S Awad, Mohamed M Osman and Ali A Abdel Azeem
    Citation: Diagnostic Pathology 2008 3:45
    Content type: Research Published on:

  33. Renal epithelial tumors are morphologically, biologically, and clinically heterogeneous. Different morphologic subtypes require specific management due to markedly different prognosis and response to therapy. ...

    Authors: Jill M Hagenkord, Anil V Parwani, Maureen A Lyons-Weiler, Karla Alvarez, Robert Amato, Zoran Gatalica, Jose M Gonzalez-Berjon, Leif Peterson, Rajiv Dhir and Federico A Monzon
    Citation: Diagnostic Pathology 2008 3:44
    Content type: Research Published on:

  35. Male breast cancer is rare compared to its female counterpart representing less than 1% of cancer in men. Moreover, mucinous carcinoma of the male breast is an extremely rare histological subtype of malignancy...

    Authors: Dimitrios Peschos, Elena Tsanou, Pavlos Dallas, Konstantinos Charalabopoulos, Christos Kanaris and Anna Batistatou
    Citation: Diagnostic Pathology 2008 3:42
    Content type: Case Report Published on:

  36. Human epidermal growth factor receptor 2 (HER2) fluorescence in situ hybridization (FISH) is a quantitative assay for selecting breast cancer patients for trastuzumab therapy. However, current HER2 FISH procedure...

    Authors: Hiroaki Nitta, Beatrice Hauss-Wegrzyniak, Megan Lehrkamp, Adrian E Murillo, Fabien Gaire, Michael Farrell, Eric Walk, Frederique Penault-Llorca, Masafumi Kurosumi, Manfred Dietel, Lin Wang, Margaret Loftus, James Pettay, Raymond R Tubbs and Thomas M Grogan
    Citation: Diagnostic Pathology 2008 3:41
    Content type: Methodology Published on:

  38. The distinction between metastasis from a colorectal adenocarcinoma into the ovary and an ovarian adenocarcinoma is vital, but challenging at times, due to overlapping morphological features. Similarly, a dist...

    Authors: Bharat Rekhi, Sophia George, Bhulaxmi Madur, RF Chinoy, Rajesh Dikshit and Amita Maheshwari
    Citation: Diagnostic Pathology 2008 3:39
    Content type: Software Published on:

  40. The Seeplex™ TB Detection-2 assay (Rockville, MD) is a nested endpoint PCR for the Mycobacterium tuberculosis complex (MTBC) targets IS6110 and MPB64 that utilizes dual priming oligonucleotide technology. When us...

    Authors: Steven J Drews, AliReza Eshaghi, Daria Pyskir, Pam Chedore, Ernesto Lombos, George Broukhanski, Rachel Higgins, David N Fisman, Joanne Blair and Frances Jamieson
    Citation: Diagnostic Pathology 2008 3:37
    Content type: Short report Published on:

  41. We present the case of 80-year-old male with superficial papillary urothelial carcinoma of the urinary bladder with striking multicystic architecture with a combination of features of urothelial carcinoma with...

    Authors: Isabel Alvarado-Cabrero, Delia Pérez-Montiel and Ondrej Hes
    Citation: Diagnostic Pathology 2008 3:36
    Content type: Case Report Published on:

  42. In several tumors the transketolase activity, controlled inter alia by enzymes of the pentose phosphate pathway which is an alternative, energy generating reaction-cascade to glycolysis, has been correlated wi...

    Authors: Holger Schultz, Daniel Kähler, Detlev Branscheid, Ekkehard Vollmer, Peter Zabel and Torsten Goldmann
    Citation: Diagnostic Pathology 2008 3:35
    Content type: Short report Published on:

  44. Fibroadenomas are common benign breast tumours that display a characteristic pathological morphology, although several epithelial and stromal variations exist. A very rare histological finding is the presence ...

    Authors: Helen M Heneghan, Sean T Martin, Mary Casey, Igdam Tobbia, Fadel Benani and Kevin M Barry
    Citation: Diagnostic Pathology 2008 3:33
    Content type: Case Report Published on:

  45. Epithelial ovarian cancer is the fifth leading cause of cancer mortality among women in the United States. For this disease, differences in age-adjusted incidence and survival rates between African American an...

    Authors: Felix O Aikhionbare, Sharifeh Mehrabi, Winston Thompson, Xuebiao Yao, William Grizzle and Edward Partridge
    Citation: Diagnostic Pathology 2008 3:32
    Content type: Short report Published on:

  46. This review provides a comprehensive overview of the broad clinicopathologic spectrum of cutaneous Kaposi sarcoma (KS) lesions. Variants discussed include: usual KS lesions associated with disease progression (i....

    Authors: Wayne Grayson and Liron Pantanowitz
    Citation: Diagnostic Pathology 2008 3:31
    Content type: Review Published on:

  47. Efficient use of whole slide imaging in pathology needs automated region of interest (ROI) retrieval and classification, through the use of image analysis and data sorting tools. One possible method for data s...

    Authors: Myriam Oger, Philippe Belhomme, Jacques Klossa, Jean-Jacques Michels and Abderrahim Elmoataz
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S17
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  48. To clarify the issues associated with the applications of virtual microscopy to the daily cytology slide screening, we conducted a survey at a slide conference of cytology. The survey was conducted specificall...

    Authors: Ichiro Mori, Osamu Nunobiki, Takashi Ozaki, Emiko Taniguchi and Kennichi Kakudo
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S15
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  49. Virtual pathology is a very important tool that can be used in several ways, including interconsultations with specialists in many areas and for frozen sections. We considered in this work the use of Windows L...

    Authors: Clóvis Klock and Regina dePaulaXavier Gomes
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S13
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

  50. The application of Information and Communication Technologies (ICTs) in the field of university education can play an important role in order to fulfil the objectives of the European Space for Higher Education...

    Authors: José ErnestoMoro Rodríguez
    Citation: Diagnostic Pathology 2008 3(Suppl 1):S8
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 3 Supplement 1

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