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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Waldenström’s macroglobulinemia (WM) is defined as a lymphoplasmacytic lymphoma (LPL) involving the bone marrow (BM) with presence of IgM monoclonal protein, and comprises > 95% of all LPL cases. Rituximab-bas...

    Authors: Shojiro Ichimata, Yukiko Hata, Kazuhiro Nomoto, Tsutomu Sato and Naoki Nishida
    Citation: Diagnostic Pathology 2024 19:89
    Content type: Case Report Published on:

  2. HER2-targeted therapies have recently emerged as an option in the management of metastatic colorectal cancer (mCRC) overexpressing HER2. However, data regarding HER2 status in primary CRC and its corresponding...

    Authors: Flavia D’Angelo, Franck Monnien, Alexis Overs, Irvin Pem, Fanny Dor, Marine Abad, Sophie Felix, Zohair Selmani, Zaher Lakkis, Christophe Borg, Alexandre Doussot, Fréderic Bibeau and Chloé Molimard
    Citation: Diagnostic Pathology 2024 19:88
    Content type: Research Published on:

  3. Pulmonary hamartomas are benign lung lesions. Histopathologically, pulmonary hamartoma is composed of varying amounts of mesenchymal elements, including chondroid tissue, mature adipose tissue, fibrous stroma,...

    Authors: Xiaoming Fan, Barry Breaux, Laura Leonards and Rusella Mirza
    Citation: Diagnostic Pathology 2024 19:87
    Content type: Case Report Published on:

  4. Follicular lymphoma (FL) is characterized by t(14;18)(q32;q21) involving the IGH and BCL2 genes. However, 10–15% of FLs lack the BCL2 rearrangement. These BCL2-rearrangement−negative FLs are clinically, pathologi...

    Authors: Sojung Lim, Jiwon Koh, Jeong Mo Bae, Hongseok Yun, Cheol Lee, Jin Ho Paik, Tae Min Kim and Yoon Kyung Jeon
    Citation: Diagnostic Pathology 2024 19:86
    Content type: Case Report Published on:

  5. Human pulmonary dirofilariasis (HPD) is rare in Hungary, and it stems from Dirofilaria immitis, mainly transmitted through mosquito bites, with dogs as primary hosts. Despite its prevalence in veterinary settings...

    Authors: Levente Kuthi, Tamás Zombori, László Tiszlavicz, Fanni Hegedűs, Szintia Almási, Bence Baráth, Mohammed Almakrami, Mohammad Jamal EJ, Nikolett Barta, Zsuzsanna Ujfaludi, Tibor Pankotai, Adrienn Hajdu, József Furák and Anita Sejben
    Citation: Diagnostic Pathology 2024 19:85
    Content type: Case Report Published on:

  6. Psoriasis is a disease of overactive immune system. OVOL1 and Filaggrin have been associated with many inflammatory skin lesions. To the best of our knowledge, the correlation between OVOL1 and Filaggrin in ps...

    Authors: Aiat Shaban Hemida, Mostafa Ahmed Hammam, Aya Ahmed Swilam and Wafaa Ahmed Shehata
    Citation: Diagnostic Pathology 2024 19:84
    Content type: Research Published on:

  7. Catenin (Cadherin-Associated Protein), Beta 1 (CTNNB1) genomic alterations are rare in prostate cancer (PCa). Gain-of-function mutations lead to overexpression of β-catenin, with consequent hyperactivation of the...

    Authors: Dilara Akhoundova, Stefanie Fischer, Joanna Triscott, Marika Lehner, Phillip Thienger, Sina Maletti, Muriel Jacquet, Dinda S.H. Lubis, Lukas Bubendorf, Wolfram Jochum and Mark A. Rubin
    Citation: Diagnostic Pathology 2024 19:83
    Content type: Research Published on:

  8. Ovarian clear cell carcinoma (OCCC), well known for its chemoresistance to platinum-based chemotherapy, exhibited a good response in clinical trials of anti–PD-1/PD-L1 inhibitors. By assessing PD-L1 expression...

    Authors: Yike Gao, Boju Pan, Hongbao Jia, Yang Zhang, Shu Wang, Yuming Wang, Sumei Zhang, Mei Li, Anqi Wang, Xiaoxi Wang, Kun Zhao, Zixin Zhang, Jian Sun, Dan Guo and Zhiyong Liang
    Citation: Diagnostic Pathology 2024 19:82
    Content type: Research Published on:

  9. Neuroendocrine carcinoma arising from the urachus is extremely rare. We describe a case of a 33-year-old gentleman who presented with hematuria and diagnosed to have a composite adenocarcinoma and small cell n...

    Authors: Sarah Obiedat, Khaled Murshed, Lajos Szabados, Khaled Al Rumaihi and Issam Al Bozom
    Citation: Diagnostic Pathology 2024 19:81
    Content type: Case Report Published on:

  10. Intravascular papillary endothelial hyperplasia (IPEH) represents an uncommon reactive endothelial hyperplastic proliferation. A 46-year-old man experienced increased volume in the right maxilla, elevation of...

    Authors: Mateus José Dutra, Ana Lia Anbinder, Christyan Moretti Pereira, Beatriz Afonso Chiliti, André Caroli Rocha and Estela Kaminagakura
    Citation: Diagnostic Pathology 2024 19:80
    Content type: Case Report Published on:

  11. Osteosarcoma is a bone tumor that is characterized by high malignancy and a high mortality rate, and that originates from primitive osteoblastic mesenchymal cells and is most common in rapidly growing long bon...

    Authors: Jiabin Lai, Weike Kong, Qiangchang Fu, Zhaochang Jiang, Bohao Sun, Xin Ye, Jing Kong, Shumei Wei and Lifeng Jiang
    Citation: Diagnostic Pathology 2024 19:79
    Content type: Research Published on:

  12. Inflammatory rhabdomyoblastic tumors are relatively recently recognized soft tissue tumors with a low malignant potential. Here, we present a case of concurrent inflammatory rhabdomyoblastic tumor (IRMT), adre...

    Authors: Otto Jokelainen, Heidi Myllykangas, Katri Rajala, Jarkko Marttila and Reijo Sironen
    Citation: Diagnostic Pathology 2024 19:78
    Content type: Case Report Published on:

  14. CIC-rearranged sarcomas (CRS) represent a new entity of undifferentiated small round cell sarcoma belonging to the Ewing-like sarcomas family. CRS are the most common type. Fusion partners for the CIC gene includ...

    Authors: Lina Zhao, Huihua He, Jiacai Ren, Yabing Huang, Honglin Yan and Jingping Yuan
    Citation: Diagnostic Pathology 2024 19:76
    Content type: Case Report Published on:

  15. Tumor grade determines prognosis in urothelial carcinoma. The classification of low and high grade is based on nuclear morphological features that include nuclear size, hyperchromasia and pleomorphism. These f...

    Authors: Ibrahim Fahoum, Shlomo Tsuriel, Daniel Rattner, Ariel Greenberg, Asia Zubkov, Rabab Naamneh, Orli Greenberg, Valentina Zemser-Werner, Gilad Gitstein, Rami Hagege and Dov Hershkovitz
    Citation: Diagnostic Pathology 2024 19:75
    Content type: Research Published on:

  16. Polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes (POEMS) syndrome is a rare plasma cell (PC) neoplasm with associated paraneoplastic syndrome. According to the current diagnostic crite...

    Authors: Han-Yue Xue, Lin Zhou, Qin-Zhao Yuan, Yang Zhang, Yi-Qun Hao, Shao-Wei Chen, Hong-Kun Wang and Fang Wei
    Citation: Diagnostic Pathology 2024 19:74
    Content type: Case Report Published on:

  18. Primary testicular lymphoma (PTL) is relatively rare. The contralateral testis is a common site of PTL relapse; therefore, once complete remission is achieved, radiation therapy (RT) is administered to the con...

    Authors: Naoya Ishibashi, Yoko Nakanishi, Toshiya Maebayashi, Katsuhiro Miura, Sumie Ohni, Shinobu Masuda, Yasuo Amano and Masahiro Okada
    Citation: Diagnostic Pathology 2024 19:72
    Content type: Case Report Published on:

  19. Current diagnostic criteria of adrenocortical neoplasms are mostly based on morphology. The utility of immunohistochemistry (IHC) and histochemistry is limited.

    Authors: Wenting Gan, Xue Han, Yuxi Gong, Yefan Yang, Cong Wang and Zhihong Zhang
    Citation: Diagnostic Pathology 2024 19:71
    Content type: Research Published on:

  20. IDH1 and IDH2 mutational status is a critical biomarker with diagnostic, prognostic, and treatment implications in glioma. Although IDH1 p.R132H-specific immunohistochemistry is available, it is unable to identif...

    Authors: James P. Solomon, Carlos Munoz-Zuluaga, Cheyanne Slocum, Alicia Dillard, Lin Cong, Jiajing Wang, Neal Lindeman, Michael Kluk, Benjamin Liechty, David Pisapia, Hanna Rennert and Priya D. Velu
    Citation: Diagnostic Pathology 2024 19:70
    Content type: Brief Report Published on:

  22. Primary malignant hepatic vascular tumors with various malignant potentials include epithelioid hemangioendothelioma (EHE) and angiosarcoma (AS), which may overlap pathologically. This study aimed to compare t...

    Authors: Youngeun Yoo, Jinho Shin, Eunsung Jun, Eun-Young Koh, Hwa Jeong Shin and Hyo Jeong Kang
    Citation: Diagnostic Pathology 2024 19:68
    Content type: Research Published on:

  23. Prostate cancer is the leading cause of cancer-related death and the second most commonly diagnosed cancer among men in Uganda and most countries in Sub-Saharan Africa (SSA). The TMPRSS2-ERG fusion gene is the...

    Authors: Yekosani Mitala, Brian Ssenkumba, Abraham Birungi, Ritah Kiconco, Marvin Mwesigwa Mutakooha and Raymond Atwine
    Citation: Diagnostic Pathology 2024 19:67
    Content type: Research Published on:

  24. TFEB/6p21/VEGFA-amplified renal cell carcinoma (RCC) is rare and difficult to diagnose, with diverse histological patterns and immunohistochemical and poorly defined molecular genetic characteristics.

    Authors: Ruiqi Zhang, Meili Ding, Xingyao Zhu, Xiang Li, Qi Hu, Lin Tao, Wenhao Hu and Hong Zou
    Citation: Diagnostic Pathology 2024 19:66
    Content type: Research Published on:

  25. MEIS1::NCOA2 is a rare fusion gene that has been recently described in a subset of spindle cell rhabdomyosarcomas and multiple low-grade undifferentiated spindle cell sarcomas predominantly arising in the genitou...

    Authors: Zachary Coty-Fattal, Bianca Carter, Michael J. Volek and Farres Obeidin
    Citation: Diagnostic Pathology 2024 19:65
    Content type: Case Report Published on:

  26. A rare case of neuroendocrine cell tumor (NET) having both conventional and mucinous components was reported. Mucinous NET is rarely encountered in the pathological diagnosis of gastrointestinal (GI) tumors. H...

    Authors: Tamotus Sugai, Noriyuki Uesugi, Masamichi Suzuki, Nobuyasu Suzuki, Michitaka Honda, Tsuyoshi Abe and Naoki Yanagawa
    Citation: Diagnostic Pathology 2024 19:64
    Content type: Case Report Published on:

  27. Squamous cell carcinoma (SCC) of the dorsum of the tongue is extremely rare, and it clinically resembles various benign lesions. Somatic mutations in TP53 and some driver genes were implicated in the development ...

    Authors: Sawako Ono, Katsutoshi Hirose, Shintaro Sukegawa, Kyoichi Obata, Masanori Masui, Kazuaki Hasegawa, Ai Fujimura, Katsumitsu Shimada, Satoko Nakamura, Akari Teramoto, Yumiko Hori, Eiichi Morii, Daisuke Motooka, Takuro Igawa, Takehiro Tanaka, Hitoshi Nagatsuka…
    Citation: Diagnostic Pathology 2024 19:63
    Content type: Brief Report Published on:

  28. Alveolar soft part sarcoma is a rare tumour of soft tissues, mostly localized in muscles or deep soft tissues of the extremities. In rare occasions, this tumour develops in deep tissues of the abdomen or pelvis.

    Authors: René Guérin, Anne-Lise Menard, Emilie Angot, Nicolas Piton, Pierre Vera, Lilian Schwarz, Jean-Christophe Sabourin, Marick Laé and Pierre-Alain Thiébaut
    Citation: Diagnostic Pathology 2024 19:62
    Content type: Case Report Published on:

  29. EBUS-TBNA has emerged as an important minimally invasive procedure for the diagnosis and staging of lung cancer. Our objective was to evaluate the effect of different specimen preparation from aspirates on the...

    Authors: Hansheng Wang, Jiankun Wang, Yan Liu, Yunyun Wang, Yanhui Zhou, Dan Yu, Hui You, Tao Ren, Yijun Tang and Meifang Wang
    Citation: Diagnostic Pathology 2024 19:61
    Content type: Research Published on:

  30. MNDA (myeloid nuclear differentiation antigen) has been considered as a potential diagnostic marker for marginal zone lymphoma (MZL), but its utility in distinguishing MZL from other B-cell non-Hodgkin lymphom...

    Authors: Li-Fen Zhang, Yan Zhang, Rou-Hong Shui, Hong-Fen Lu, Wen-Hua Jiang, Xu Cai, Xiao-Qiu Li and Bao-Hua Yu
    Citation: Diagnostic Pathology 2024 19:60
    Content type: Research Published on:

  31. PEComa is a mesenchymal tumor that can occur in various organs including the uterus and soft tissues. PEComas are composed of perivascular epithelioid cells, and angiomyolipoma (AML), clear cell sugar tumor (C...

    Authors: Hikaru Tsukita, Kei Koyama, Takahiro Ishinari, Ayana Takahashi, Ken Miyabe, Michinobu Umakoshi, Makoto Yoshida, Yukitsugu Kudo-Asabe, Akiko Nishida, Naohiko Otsuka, Ouki Yasui, Ikuma Kato, Noriyoshi Fukushima and Akiteru Goto
    Citation: Diagnostic Pathology 2024 19:59
    Content type: Case Report Published on:

  32. Crizotinib, an oral first-generation tyrosine kinase inhibitor (TKI), is superior to systemic chemotherapy for the treatment of non-small cell lung cancer (NSCLC) with positive rearrangement of anaplastic lymp...

    Authors: Peng Zhang, JiaHua Xu, Qing Wu, Jianxin Qian and Song Wang
    Citation: Diagnostic Pathology 2024 19:58
    Content type: Case Report Published on:

  33. Cementoblastoma is a rare odontogenic tumor characterized by the formation of osteocementum-like tissue on a tooth root directly by neoplastic cementoblasts. Although it is categorized as benign, it has a high...

    Authors: Kaori Oya, Akinori Takeshita, Kanta Wakamori, Misa Song, Hayato Kimura, Katsutoshi Hirose, Hiroaki Shimamoto, Sunao Sato, Kazuhide Matsunaga, Narikazu Uzawa and Satoru Toyosawa
    Citation: Diagnostic Pathology 2024 19:57
    Content type: Case Report Published on:

  35. Colorectal cancer (CRC) frequently involves mutations in the KRAS gene, impacting therapeutic strategies and prognosis. The occurrence of KRAS mutations typically precludes the presence of RET fusions, with curre...

    Authors: Tillmann Bedau, Carina Heydt, Udo Siebolts, Thomas Zander, Max Kraemer, Heike Loeser, Reinhard Buettner and Alexander Quaas
    Citation: Diagnostic Pathology 2024 19:55
    Content type: Case Report Published on:

  36. Melanocytic lesions involving the central nervous system are extremely rare and pose a diagnostic challenge owing melanoma being the third most common malignancy metastasizing to the spine. Morphology and immu...

    Authors: Raghav Kapoor, Anurag Mehta, Anila Sharma, Shrinidhi Nathany, Himanshi Diwan and Divya Bansal
    Citation: Diagnostic Pathology 2024 19:54
    Content type: Case Report Published on:

  37. Accurately predicting the response to neoadjuvant chemotherapy (NAC) in breast cancer patients is crucial for guiding treatment strategies and enhancing clinical outcomes. Current studies have primarily focuse...

    Authors: Mijia Wang, Zhendong Wei, Jixia Kong and Haidong Zhao
    Citation: Diagnostic Pathology 2024 19:53
    Content type: Research Published on:

  38. Papillary carcinoma is the most frequent type of thyroid carcinoma, while primary thyroid lymphoma is uncommon disease. The coexistence of these entities has already been described, and the common risk factor ...

    Authors: Igor Iskra, Maja Ilić Tomaš, Tatjana Bogović Crnčić, Edvin Kukić, Ita Hadžisejdić, Manuela Avirović and Neva Girotto
    Citation: Diagnostic Pathology 2024 19:52
    Content type: Case Report Published on:

  39. Oral squamous cell carcinoma in minors is considered to be a distinct entity from OSCC in older patients, with an uncertain etiology. Human papillomavirus (HPV) infection may trigger the initiation and promote...

    Authors: Ningxiang Wu, Yonghui Li, Xiaokun Ma, Zhen Huang, Zhuoxuan Chen, Weihua Chen and Ran Zhang
    Citation: Diagnostic Pathology 2024 19:51
    Content type: Research Published on:

  42. Patients with hypopharyngeal carcinoma (HPC) have a poor prognosis mainly because of lymphatic metastasis. This research aimed to determine the PKM2 role in lymphatic metastasis in HPC and the underlying molec...

    Authors: Xin Zhou, Yanshi Li, Min Pan, Tao Lu, Chuan Liu, Zhihai Wang, Fengxiang Tang and Guohua Hu
    Citation: Diagnostic Pathology 2024 19:48
    Content type: Research Published on:

  43. Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron disease. Due to the limited knowledge about potential biomarkers that help in early diagnosis and monitoring disease progression, tod...

    Authors: Shahram Darabi, Armin Ariaei, Auob Rustamzadeh, Dariush Afshari, Enam Alhagh Charkhat Gorgich and Leila Darabi
    Citation: Diagnostic Pathology 2024 19:47
    Content type: Review Published on:

  44. Primary mucoepidermoid carcinomas (MECs) of the sinonasal tract and nasopharynx are rare entities that represent a diagnostic challenge, especially in biopsy samples. Herein, we present a case series of MECs o...

    Authors: Chunyan Hu, Lan Lin, Ming Ye, Yifeng Liu, Qiang Huang, Cuncun Yuan, Ji Sun and Hui Sun
    Citation: Diagnostic Pathology 2024 19:46
    Content type: Research Published on:

  45. Fungal infection incidental detection is a common encounter in cytopathology practices. Detection of the fungal organisms and awareness of the morphological features are challenges for the cytopathologist.

    Authors: Tummidi Santosh, Indranil Chakrabarti, Aparna Palit and Sonakshi Srivastava
    Citation: Diagnostic Pathology 2024 19:45
    Content type: Case Report Published on:

  46. Lymph node ratio (LNR) may offer superior prognostic stratification in colorectal adenocarcinoma compared with N stage. However, candidate cutoff ratios require validation. We aimed to study the prognostic sig...

    Authors: Amir F. Beirat, Justin Z. Amarin, Haya H. Suradi, Yasmeen Z. Qwaider, Adel Muhanna, Bayan Maraqa, Abdallah Al-Ani and Maysa Al-Hussaini
    Citation: Diagnostic Pathology 2024 19:44
    Content type: Research Published on:

  47. The integration of large language models (LLMs) like ChatGPT in diagnostic medicine, with a focus on digital pathology, has garnered significant attention. However, understanding the challenges and barriers as...

    Authors: Ehsan Ullah, Anil Parwani, Mirza Mansoor Baig and Rajendra Singh
    Citation: Diagnostic Pathology 2024 19:43
    Content type: Review Published on:

  48. Staining tissue samples to visualise cellular detail and tissue structure is at the core of pathology diagnosis, but variations in staining can result in significantly different appearances of the tissue sampl...

    Authors: Catriona Dunn, David Brettle, Martin Cockroft, Elizabeth Keating, Craig Revie and Darren Treanor
    Citation: Diagnostic Pathology 2024 19:42
    Content type: Research Published on:

  49. Fat-forming solitary fibrous tumor is a rare and specific subtype of solitary fibrous tumor. In this case, a mass of 8.3 cm in diameter was found in a 59-year-old male patient’s right retroperitoneum, as revea...

    Authors: Yi-Dan Ma, Zi-Qing Wu, Xin-Rong Liang, Lin Jing Pi, Meng-Zhen Gong and Yao Tang
    Citation: Diagnostic Pathology 2024 19:40
    Content type: Case Report Published on:
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Diagnostic Pathology

ISSN: 1746-1596

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