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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  2. Emerging evidences indicate that dysregulated long non-coding RNAs (lncRNAs) are implicated in cancer tumorigenesis and progression. LncRNA ANRIL has been shown to promote the progression of gastric cancer. Ho...

    Authors: Ling Lin, Zhi-Tao Gu, Wen-Hu Chen and Ke-Jian Cao
    Citation: Diagnostic Pathology 2015 10:14
    Content type: Research Published on:

  3. Chronic allograft vasculopathy (CAV) is a major mechanism of graft failure of transplanted organs in humans. Morphometric analysis of coronary arteries enables the quantitation of CAV in mouse models of heart ...

    Authors: László Fónyad, Kazunobu Shinoda, Evan A Farkash, Martin Groher, Divya P Sebastian, A Marcell Szász, Robert B Colvin and Yukako Yagi
    Citation: Diagnostic Pathology 2015 10:16
    Content type: Methodology Published on:

  4. Patients with pathologic stage (p-Stage) IA non-small cell lung cancer (NSCLC) have a good survival rate because of possible curative resection. However, up to 10% of these patients relapse postoperatively. To...

    Authors: Rurika Hamanaka, Tomoyuki Yokose, Yuji Sakuma, Masahiro Tsuboi, Hiroyuki Ito, Haruhiko Nakayama, Kouzo Yamada, Ryota Masuda and Masayuki Iwazaki
    Citation: Diagnostic Pathology 2015 10:17
    Content type: Research Published on:

  5. Angiotensin II (Ang II) and transforming growth factor β (TGFβ) are closely involved in the pathogenesis of diabetic complications. We aimed to determine whether an aberrant thrombospondin 1 (TSP1)–mediated TG...

    Authors: Hui Sun, Yong Zhao, Xiuping Bi, Shaohua Li, Guohai Su, Ya Miao, Xiao Ma, Yun Zhang, Wei Zhang and Ming Zhong
    Citation: Diagnostic Pathology 2015 10:18
    Content type: Research Published on:

  6. The present study sought to investigate the effects of Tarantula cubensis extract (TC; Theranekron®) on the histopathological scores of peritoneal wound healing after laparotomy in the rats.

    Authors: Farajollah Adib-Hashemi, Farshad Farahmand, Shamim Fattah Hesari, Bijan Rezakhaniha, Ehsan Fallah, Amir Farshid Fayyaz and Masoomeh Dadpay
    Citation: Diagnostic Pathology 2015 10:19
    Content type: Research Published on:

    The Retraction Note to this article has been published in Diagnostic Pathology 2016 11:118

  7. Persistent high-risk human papillomavirus (HR-HPV) infection has been implicated in the development of high-grade cervical intraepithelial neoplasia (CIN) and cervical cancer. Invariant natural killer T (iNKT)...

    Authors: Ting Hu, Pei Yang, Hongmei Zhu, Xinlian Chen, Xiaoyan Xie, Mei Yang, Shanling Liu and He Wang
    Citation: Diagnostic Pathology 2015 10:20
    Content type: Research Published on:

  8. The aim of this study was to analyze the frequency of Thyroid Transcription Factor (TTF)-1 expression in small cell lung cancer (SCLC) and its value for the diagnosis of SCLC, the response to first line treatm...

    Authors: Daniel Misch, Torsten Blum, Christian Boch, Timo Weiss, Catharina Crolow, Sergej Griff, Thomas Mairinger, Torsten T Bauer and Jens Kollmeier
    Citation: Diagnostic Pathology 2015 10:21
    Content type: Research Published on:

  9. MicroRNA-23a (miR-23a) has been demonstrated to play an important role in the development of several types of cancer, but its role in tumorigenesis of laryngeal carcinoma is still unclear. The aim of this stud...

    Authors: Xiao-Wen Zhang, Ning Liu, Sheng Chen, Ye Wang, Zhao-Xiong Zhang, Yuan-Yuan Sun, Guang-Bin Qiu and Wei-Neng Fu
    Citation: Diagnostic Pathology 2015 10:22
    Content type: Research Published on:

  10. Gout is a metabolic disorder that results in hyperuricemia and the deposition of positively birefringent monosodium urate crystals in various parts of the body. The purpose of this study was to characterize th...

    Authors: Alireza Nasoori, Behnam Pedram, Zahra Kamyabi-Moghaddam, Aram Mokarizadeh, Hamid Pirasteh, Amir Farshid Fayyaz and Mohammad Barat Shooshtari
    Citation: Diagnostic Pathology 2015 10:23
    Content type: Case Report Published on:

    The Retraction Note to this article has been published in Diagnostic Pathology 2016 11:123

  13. The ATP-Binding Cassette (ABC)-transporter MultiDrug Resistance Protein 1 (MDR1) and Multidrug Resistance Related Protein 1 (MRP1) are expressed on the surface of enterocytes, which has led to the belief that ...

    Authors: Tamás Micsik, András Lőrincz, Tamás Mersich, Zsolt Baranyai, István Besznyák Jr, Kristóf Dede, Attila Zaránd, Ferenc Jakab, László Krecsák Szöllösi, György Kéri, Richard Schwab and István Peták
    Citation: Diagnostic Pathology 2015 10:26
    Content type: Research Published on:

  14. Nemaline myopathy is a rare genetic muscle disorder defined by the presence of nemaline rods in the muscle fibre sarcoplasm. Congenital nemaline myopathy is the most serious form of the disease’s spectrum.

    Authors: Jariya Waisayarat, Chinnawut Suriyonplengsaeng, Chaiyos Khongkhatithum and Mana Rochanawutanon
    Citation: Diagnostic Pathology 2015 10:27
    Content type: Case Report Published on:

  16. Vascular events represent the most frequent complications of thrombocytemias. We aimed to evaluate their risk in the WHO histologic categories of Essential Thrombocytemia (ET) and early Primary Myelofibrosis (...

    Authors: Serena Rupoli, Gaia Goteri, Paola Picardi, Giorgia Micucci, Lucia Canafoglia, Anna Rita Scortechini, Irene Federici, Federica Giantomassi, Lidia Da Lio, Antonio Zizzi, Elisa Honorati and Pietro Leoni
    Citation: Diagnostic Pathology 2015 10:29
    Content type: Research Published on:

  17. The prognosis for pancreatic cancer (PC) is very poor. The SnoN gene may have a role in cell proliferation and apoptosis in human cancer. However, the influence of SnoN on cell proliferation and apoptosis in huma...

    Authors: Chengli Liu, Hui Zhang, Xiaoxia Zang, Cheng Wang, Yalin Kong and Hongyi Zhang
    Citation: Diagnostic Pathology 2015 10:30
    Content type: Research Published on:

  18. Perivascular epithelioid cell tumor (PEComa) is a rare entity originating from mesenchymal tissue, which stains for both melanocytic and smooth muscle markers. We would like to present an unusual case of the P...

    Authors: Jarosław Wejman, Krzysztof Nowak, Lena Gielniewska, Magdalena Komorowska and Wojciech Dąbrowski
    Citation: Diagnostic Pathology 2015 10:31
    Content type: Case Report Published on:

  19. Encapsulated follicular tumours with equivocal papillary thyroid carcinoma (PTC) type nuclear features continue to remain a challenge despite the recent attempts to classify these borderline lesions. The term ...

    Authors: Monika Lamba Saini, Birgit Weynand, Jacques Rahier, Michel Mourad, Marc Hamoir and Etienne Marbaix
    Citation: Diagnostic Pathology 2015 10:32
    Content type: Research Published on:

  20. Complement 5a receptor (C5aR) was demonstrated a receptor of complement 5a (C5a) which is involved in many inflammatory diseases. The functional responses attributed to C5a results from its interaction with it...

    Authors: Ying-Ying Zheng, Xiang Xie, Yi-Tong Ma, Yi-Ning Yang, Zhen-Yan Fu, Xiao-Mei Li, Shuo Pan, Dilare Adi, Bang-Dang Chen and Fen Liu
    Citation: Diagnostic Pathology 2015 10:33
    Content type: Research Published on:

  21. Glypican-3 (GPC3) is an oncofetal protein which is encoded by GPC3 gene and takes role in the regulation of cell division and apoptosis. Overexpression of GPC3 has been reported in some types of cancer such as...

    Authors: Oguz Aydin, Levent Yildiz, Sancar Baris, Cihad Dundar and Filiz Karagoz
    Citation: Diagnostic Pathology 2015 10:34
    Content type: Research Published on:

  22. Somatic cells could be reprogrammed to induced pluripotent stem cells (iPS) by ectopic expression of OCT4, SOX2, KLF4 and MYC (OSKM). We aimed to gain insights into the early mechanisms underlying the inductio...

    Authors: Yanning Cai, Xianhua Dai, Qianhua Zhang and Zhiming Dai
    Citation: Diagnostic Pathology 2015 10:35
    Content type: Research Published on:

  24. Medulloblastoma is a malignant, invasive embryonal tumor of the cerebellum and accounts for 20% of intracranial tumors in children. QSOX1, whose functions include formation of disulphide bridges, which are nee...

    Authors: Ana Cristina Lira Sobral, Victor Moreschi Neto, Gabriela Traiano, Ana Paula Percicote, Elizabeth Schneider Gugelmin, Cleber Machado de Souza, Lia Nakao, Luiz Fernando Bleggi Torres and Lucia de Noronha
    Citation: Diagnostic Pathology 2015 10:37
    Content type: Research Published on:

  25. Pancreatic ductal adenocarcinoma is an aggressive malignancy with late presentation, metastatic potential and very poor prognosis. Therefore, there is an urgent need for novel diagnostic and prognostic biomark...

    Authors: Petra Vychytilova-Faltejskova, Igor Kiss, Sona Klusova, Jan Hlavsa, Vladimir Prochazka, Zdenek Kala, Jan Mazanec, Jitka Hausnerova, Leos Kren, Marketa Hermanova, Jiri Lenz, Petr Karasek, Rostislav Vyzula and Ondrej Slaby
    Citation: Diagnostic Pathology 2015 10:38
    Content type: Short report Published on:

  26. Crohn’s disease is a systemic disease and sometimes involves the testicle, usually leading to granulomatous lesions. We report herein a case of focal non-granulomatous orchitis in a 21-year-old patient with ac...

    Authors: Nicolas Piton, Marie-Laurence Roquet, Louis Sibert and Jean-Christophe Sabourin
    Citation: Diagnostic Pathology 2015 10:39
    Content type: Case Report Published on:

  28. In Nigeria, despite the change in National malaria drug policy to artemisinin combination therapy (ACT) in 2005 due to widespread chloroquine resistance, chloroquine (CQ) is still widely used in the treatment ...

    Authors: Oladosu O Oladipo, Oyibo A Wellington and Colin J Sutherland
    Citation: Diagnostic Pathology 2015 10:41
    Content type: Research Published on:

  29. Esophageal cancer is the malignant tumor with very poor prognosis and increasing incidence often diagnosed at very late stage, so the prognosis of affected patients is unsatisfactory, despite the development o...

    Authors: Renata Hezova, Alena Kovarikova, Josef Srovnal, Milada Zemanova, Tomas Harustiak, Jiri Ehrmann, Marian Hajduch, Marek Svoboda, Milana Sachlova and Ondrej Slaby
    Citation: Diagnostic Pathology 2015 10:42
    Content type: Short report Published on:

  31. Immunophenotyping is a valuable ancillary technique for the differential diagnosis between myelodysplastic syndromes (MDS) with low bone marrow (BM) blast counts and a normal karyotype, and reactive peripheral...

    Authors: Suiellen C Reis-Alves, Fabiola Traina, Konradin Metze and Irene Lorand-Metze
    Citation: Diagnostic Pathology 2015 10:44
    Content type: Research Published on:

  34. Atypical teratoid/rhabdoid tumors are rare and highly malignant central nervous system tumors. They have no specific radiological features and often present several histological components that make a problem ...

    Authors: Youssef Mahdi, Jinane Kharmoum, Amal Alouan, Hakima Elouarradi, Iman Elkhiyat, Mustapha Maher, Moulay Zahid Benchrif, Amina Kili, Rajae Daoudi and Nadia Cherradi
    Citation: Diagnostic Pathology 2015 10:47
    Content type: Case Report Published on:

  36. The pathogenesis of malaria during pregnancy is not completely understood. There are few published data on complement activation and malaria during pregnancy. This study aimed to investigate complement activat...

    Authors: Ammar Alim, Naser E.Bilal, Awad-Elkareem Abass, Elhassan M Elhassan, Ahmed A Mohmmed and Ishag Adam
    Citation: Diagnostic Pathology 2015 10:49
    Content type: Research Published on:

  37. Special AT-rich sequence binding protein 1 (SATB1) is found acting as a “genome organizer” that functions as a landing platform to regulate tissue-specific gene ex-pression. In breast cancer cell lines it has ...

    Authors: Xiangdong Liu, Yan Zheng, Chuanwu Qiao, Fei Qv, Jingnan Wang, Butong Ding, Yuping Sun and Yunshan Wang
    Citation: Diagnostic Pathology 2015 10:50
    Content type: Research Published on:

  39. Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disorder characterized by systemic platelet-von Willebrand factor aggregation, organ ischemia and profound thrombocytopenia. In this report, we d...

    Authors: Takashi Tasaki, Sohsuke Yamada, Atsunori Nabeshima, Hirotsugu Noguchi, Aya Nawata, Masanori Hisaoka, Yasuyuki Sasaguri and Toshiyuki Nakayama
    Citation: Diagnostic Pathology 2015 10:52
    Content type: Case Report Published on:

  40. The differential diagnosis of benign and malignant effusion is often hampered by low cell content or insufficiently preserved tumor cells. In this study, we evaluated the combined diagnostic value of six tumor...

    Authors: Till Braunschweig, Joon-Yong Chung, Chel Hun Choi, Hanbyoul Cho, Qing-Rong Chen, Ran Xie, Candice Perry, Javed Khan and Stephen M Hewitt
    Citation: Diagnostic Pathology 2015 10:53
    Content type: Research Published on:

  43. Breast cancer is a heterogeneous disease with various histological features and molecular markers. These are utilized for the prediction of clinical outcome and therapeutic decision making. In addition to well...

    Authors: Cornelis J. J. Huijsmans, Adriaan J. C. van den Brule, Henny Rigter, Jeroen Poodt, Johannes C. van der Linden, Paul H. M. Savelkoul, Mirrian Hilbink and Mirjam H. A. Hermans
    Citation: Diagnostic Pathology 2015 10:56
    Content type: Methodology Published on:

  44. Treatment decisions in advanced non-small cell lung cancer rely on accurate analysis of the EGFR mutation status in small tissue samples. Sanger sequencing of PCR products is unbiased and cheap, but its detection...

    Authors: Liesbet Vliegen, Christophe Dooms, Wim De Kelver, Eric Verbeken, Johan Vansteenkiste and Peter Vandenberghe
    Citation: Diagnostic Pathology 2015 10:57
    Content type: Methodology Published on:

  45. Malignant gliomas are characterized by the tendency of cancerous glial cells to infiltrate into normal brain tissue, thereby complicating targeted treatment of this type of cancer. Recent studies suggested inv...

    Authors: Paulina Vaitkienė, Daina Skiriutė, Giedrius Steponaitis, Kęstutis Skauminas, Arimantas Tamašauskas and Arunas Kazlauskas
    Citation: Diagnostic Pathology 2015 10:58
    Content type: Short report Published on:

  46. Human papillomavirus (HPV) inactivates the retinoblastoma 1 (RB1) gene by promoter methylation and reduces cellular E-cadherin expression by overexpression of DNA methyltransferase 1 (DNMT1). The Epstein-Barr vir...

    Authors: Thaís M McCormick, Nathalie HS Canedo, Yara L Furtado, Filomena A Silveira, Roberto J de Lima, Andréa DF Rosman, Gutemberg L Almeida Filho and Maria da Glória da C Carvalho
    Citation: Diagnostic Pathology 2015 10:59
    Content type: Research Published on:

  47. Tubular adenoma of the breast is a rare benign epithelial tumor and only a few literatures have been reported; so far, no cases of tubular adenoma occurred in the accessory breast have been reported in the Eng...

    Authors: Yaoyu Huang, Hao Zhang, Qian Zhou, Lijun Ling and Shui Wang
    Citation: Diagnostic Pathology 2015 10:60
    Content type: Case Report Published on:

  48. Intrapulmonary thyroid tissue with no malignant history of the thyroid gland is extremely rare. Usually, it is interpreted as ectopic thyroid tissue. Here we describe a case of bilateral pulmonary thyroid nodu...

    Authors: Henghui Cheng, Lili Yang, Jing Xiong, Jian Peng and Qiurong Ruan
    Citation: Diagnostic Pathology 2015 10:61
    Content type: Case Report Published on:

  50. The relationships between lncRNAs and tumors have currently become one of the focuses on cancer studies. However, there are a few studies about lncRNAs in non-small cell lung cancer (NSCLC) at present.

    Authors: Ping Li, Juan Li, Rui Yang, Furui Zhang, Huaqi Wang, Heying Chu, Yao Lu, Shaozhi Dun, Yuanyuan Wang, Wenqiao Zang, Yuwen Du, Xiaonan Chen, Guoqiang Zhao and Guojun Zhang
    Citation: Diagnostic Pathology 2015 10:63
    Content type: Research Published on:
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Diagnostic Pathology

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