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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. Lipoprotein glomerulopathy (LPG) is a rare autosomal dominant disease caused by mutations in APOE, the gene which encodes apolipoprotein E. LPG mainly affects Asian individuals, however occasional cases have also...

    Authors: Joaquim Nelito da Silveira-Neto, Guilherme Jinson de Oliveira Ahn, Precil Diego Miranda de Menezes Neves, Vinicius Augusto Ferreira Baptista, Stanley de Almeida Araújo, David Campos Wanderley, Andréia Watanabe, Elieser Hitoshi Watanabe, Neide Missae Murai, Eny Maria Goloni Bertollo, Osvaldo Merege Vieira-Neto, Márcio Dantas, Sergio Ricardo de Antônio, Roberto Silva Costa, Maria Alice Sperto Ferreira Baptista, Miguel Moysés-Neto…

    Citation: Diagnostic Pathology 2021 16:65

    Content type: Case Report

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  2. Diffuse malignant peritoneal mesothelioma (DMPM) is a rare malignant neoplasm with poor survival that shares some similarities with the best-known pleural variant, pleural mesothelioma. The recent European Ref...

    Authors: Federica Pezzuto, Luigi Vimercati, Francesco Fortarezza, Andrea Marzullo, Antonio Pennella, Domenica Cavone, Alessandra Punzi, Concetta Caporusso, Antonio d’Amati, Teresa Lettini and Gabriella Serio

    Citation: Diagnostic Pathology 2021 16:64

    Content type: Short report

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  3. Dermatofibrosarcoma protuberans (DFSP) is a superficial fibroblastic tumor characterized by high rate of local recurrence and low metastatic potential. Fibrosarcomatous transformation can rarely arise in DFSP ...

    Authors: Yuan Chen, Ying-zhou Shi, Xiao-he Feng, Xiao-tong Wang, Xiang-lei He and Ming Zhao

    Citation: Diagnostic Pathology 2021 16:63

    Content type: Case Report

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  4. The distribution of mucin phenotypes and their relationship with clinicopathological features in early differentiated gastric adenocarcinomas in a Chinese cohort are unknown. We aimed to investigate mucin phen...

    Authors: Kai Song, Qi Yang, Yu Yan, Xiaoyan Yu, Kanlun Xu and Jinghong Xu

    Citation: Diagnostic Pathology 2021 16:62

    Content type: Research

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  5. Central mucoepidermoid carcinoma (MEC) is a rare salivary gland tumor that affects the jawbone. Glandular odontogenic cyst (GOC) is also a rare odontogenic developmental cyst with glandular differentiation. GO...

    Authors: Satoshi Maruyama, Taisuke Mori, Manabu Yamazaki, Tatsuya Abé, Eijitsu Ryo, Hiroyuki Kano, Go Hasegawa and Jun-ichi Tanuma

    Citation: Diagnostic Pathology 2021 16:61

    Content type: Case Report

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  6. CCND1 copy number increase is characteristic of acral melanoma and is useful in distinguishing benign and malignant acral melanocytic lesions. Increase of the gene copy number may result in protein overexpression...

    Authors: Jianying Liu, Wenjuan Yu, Fei Gao, Shuangshuang Qi, Juan Du, Xiaolong Ma, Yan Zhang, Jie Zheng and Jing Su

    Citation: Diagnostic Pathology 2021 16:60

    Content type: Research

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  7. Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is rare in Asians, and patients with CLL/SLL seldomly undergo kidney biopsy. The histopathological features and clinical relevance of tubuloint...

    Authors: Hui Wang, Xiaojuan Yu, Xu Zhang, Suxia Wang and Minghui Zhao

    Citation: Diagnostic Pathology 2021 16:59

    Content type: Research

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  8. Ectopic adrenocortical tissue is a lesion usually found incidentally during autopsy or inguinal surgery. Here, we demonstrate an extremely unusual case of intrahepatic adrenocortical adenoma which highly mimic...

    Authors: Jingci Chen, Xueshuai Wan, Yao Lu, Wenze Wang, Dachun Zhao, Zhaohui Lu, Yilei Mao and Jie Chen

    Citation: Diagnostic Pathology 2021 16:58

    Content type: Case Report

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  10. Secretory carcinoma of the breast is one of the rarest entities, accounting for less than 0.15 % of all infiltrating breast carcinomas. It has characteristic histopathological and molecular features and, in ge...

    Authors: Hongping Tang, Lihua Zhong, Hongbing Jiang, Yan Zhang, Guannan Liang, Guoyan Chen and Gui’e Xie

    Citation: Diagnostic Pathology 2021 16:56

    Content type: Case Report

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  11. Undifferentiated embryonal sarcoma of liver (UESL) and hepatic mesenchymal hamartoma (HMH) are two rare entities which mainly affect the pediatric population. The aim of this investigation was to provide a com...

    Authors: Parham Habibzadeh, Mohaddese Ansari Asl, Hamid Reza Foroutan, Ali Bahador and Mohammad Hossein Anbardar

    Citation: Diagnostic Pathology 2021 16:55

    Content type: Research

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  12. The novel SS18-SSX fusion-specific antibody is reported to have high sensitivity and specificity for the diagnosis of primary synovial sarcoma (SS), which often metastasizes to the lung. Thus far, no study has...

    Authors: Kentaro Miura, Kimihiro Shimizu, Takashi Eguchi, Sachie Koike, Shunichiro Matsuoka, Tetsu Takeda, Kazutoshi Hamanaka and Takeshi Uehara

    Citation: Diagnostic Pathology 2021 16:54

    Content type: Research

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  13. Malignancy after transplantation is a leading cause of death among kidney transplant recipients. However, donor-derived malignancies are rare. We report a case of a high grade papillary urothelial carcinoma ar...

    Authors: Joyce M. Chen, G. Kenneth Haines III, William Lam, Asha Reddy, Meenakshi Mehrotra, Jane Houldsworth and Qiusheng Si

    Citation: Diagnostic Pathology 2021 16:53

    Content type: Case Report

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  14. Undifferentiated carcinoma of the biliary tract are highly aggressive malignancies. In other organs, a subgroup of undifferentiated carcinoma related to SWI/SNF complex–deficiency have been described.

    Authors: Tiemo S. Gerber, Abbas Agaimy, Arndt Hartmann, Michael Habekost, Wilfried Roth, Albrecht Stenzinger, Peter Schirmacher and Beate K. Straub

    Citation: Diagnostic Pathology 2021 16:52

    Content type: Case Report

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  15. As a new type of molecular marker, microRNAs (miRNAs) can be used for early diagnosis and prognosis prediction of malignant tumors, and has broad clinical application prospects. This paper mainly studies the i...

    Authors: He Wang, Huiwen Wang, Wenyu Cui, Qiao Zhang, Jing Li and Qi Zhang

    Citation: Diagnostic Pathology 2021 16:51

    Content type: Research

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  16. BCOR-CCNB3 sarcoma (BCS) is a group of undifferentiated small round cell sarcomas harboring the BCOR gene rearrangement which shares morphology with the Ewing sarcoma family as well as other malignant round blue ...

    Authors: Lan Li, Ming Zhang, Shaoyu Chen, Xiaoqi Sun, Hairong Xu, Lina Li, Tingting Zhang, Xiaoyuan Huang, Hongtao Ye and Yi Ding

    Citation: Diagnostic Pathology 2021 16:50

    Content type: Research

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  17. Esophageal granular cell tumor (eGCT) is rare, and the recent literature suggests a link between eosinophilic esophagitis (EoE) and eGCT. The aim of our study was to determine if EoE or other disorders associa...

    Authors: Deepti Reddi, Christropher Chandler, Diana Cardona, Michael Schild, Maria Westerhoff, Emily McMullen, Yutaka Tomizawa, Lani Clinton and Paul E. Swanson

    Citation: Diagnostic Pathology 2021 16:49

    Content type: Research

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  18. Systemic Epstein-Barr virus+ T-cell lymphoma (sEBV+ TCL) occurs in childhood and young adults, and is exceptionally rare in older adults.

    Authors: Ziyao Wang, Shoichi Kimura, Hiromi Iwasaki, Ken Takase, Yumi Oshiro, Ayako Gamachi, Kosuke Makihara, Masao Ogata, Tsutomu Daa, Seiya Momosaki, Yasushi Takamatsu and Morishige Takeshita

    Citation: Diagnostic Pathology 2021 16:48

    Content type: Research

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  19. Colorectal cancer (CRC) is one of the third normal malignancy worldwide. Taurine-upregulated gene 1 (TUG1), a member of long noncoding RNAs (lncRNAs), has been reported to be involved in various cancers. Howev...

    Authors: Quanlin Liu, Wei Zhang, Linshan Luo, Keshun Han, Ruitao Liu, Shue Wei and Xiaoran Guo

    Citation: Diagnostic Pathology 2021 16:47

    Content type: Research

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  20. Long non-coding RNA growth arrest specific 5 (GAS5) is a regulator in non-small cell lung cancer (NSCLC) progression. Nonetheless, the mechanism by which GAS5 exerts its biological function in NSCLC cells rema...

    Authors: Juan Ma, Haiyan Miao, Haiyun Zhang, Jingjing Ren, Shengyan Qu, Jing Da, Feifan Xu and Huan Zhao

    Citation: Diagnostic Pathology 2021 16:46

    Content type: Research

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  21. Triple-negative breast cancer (TNBC) is a special type of breast cancer that lacks effective therapeutic targets. There is a significant need to clarify its pathogenesis, so as to bring new targeted approaches...

    Authors: Jie Sun, Xiaohua Li, Enqiao Yu, Jianxia Liu, Liang Sun, Qin He and Qiran Lu

    Citation: Diagnostic Pathology 2021 16:45

    Content type: Research

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  22. Impaired endometrial receptivity is a major reason for embryo implantation failure. There’s a paucity of information regarding the role of circRNAs on endometrial receptivity. Here, we investigated the functio...

    Authors: Fang Zhao, Yihong Guo, Zhanrong Shi, Menglan Wu, Yuzhen Lv and Wenyue Song

    Citation: Diagnostic Pathology 2021 16:44

    Content type: Research

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  24. Effective workflow management in a diagnostic pathology laboratory is critical to achieve rapid turnover while maintaining high quality. Fluorescence in situ hybridization analysis (FISH) is the preferred tech...

    Authors: Vira Chea, Valerie Pleiner, Viviane Schweizer, Benjamin Herzog, Beata Bode and Marianne Tinguely

    Citation: Diagnostic Pathology 2021 16:42

    Content type: Short report

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  25. The objective was to build a novel method for automated image analysis to locate and quantify the number of cytokeratin 7 (K7)-positive hepatocytes reflecting cholestasis by applying deep learning neural netwo...

    Authors: Nelli Sjöblom, Sonja Boyd, Anniina Manninen, Anna Knuuttila, Sami Blom, Martti Färkkilä and Johanna Arola

    Citation: Diagnostic Pathology 2021 16:41

    Content type: Research

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  26. Patients with COVID-19 can also have enteric symptoms. Here we analyzed the histopathology of intestinal detachment tissue from a patient with COVID-19.

    Authors: Yanling Feng, Dong Zeng, Lvyin Hu, Yuexiang Yang, Shu Song, Yuhan Shi, Jingjing Xu, Wenjuan Guo, Yun Ling, Tangkai Qi, Qingguo Wu, Feng Li, Jilin Cheng and Hongzhou Lu

    Citation: Diagnostic Pathology 2021 16:40

    Content type: Case Report

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  27. Danon disease (DD) is a rare x-linked dominant multisystemic disorder with a clinical triad of severe cardiomyopathy, skeletal myopathy, and mental retardation. It is caused by a defect in the lysosomal-associ...

    Authors: Jiamin Xu, Zhu Li, Yihai Liu, Xinlin Zhang, Fengnan Niu, Hongyan Zheng, Lian Wang, Lina Kang, Kun Wang and Biao Xu

    Citation: Diagnostic Pathology 2021 16:39

    Content type: Case Report

    Published on:

  28. Gastric cancer (GC) is the 4th most common type of cancer worldwide. Different GC subtypes have unique molecular features that may have different therapeutic methods. The aim of the present study was to invest...

    Authors: Li Zhang, Yinkui Wang, Zhongwu Li, Dongmei Lin, Yiqiang Liu, Linxin Zhou, Dongliang Wang, Aiwen Wu and Ziyu Li

    Citation: Diagnostic Pathology 2021 16:38

    Content type: Research

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  30. Esophageal cancer is one of the most common malignancies among Iranians and is categorized as adenocarcinoma and squamous cell carcinoma. Various environmental and genetic factors are involved in this malignan...

    Authors: Mohammad Reza Abbaszadegan, Negin Taghehchian, Azadeh Aarabi, Faride Akbari, Ehsan Saburi and Meysam Moghbeli

    Citation: Diagnostic Pathology 2021 16:36

    Content type: Research

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  31. Small cell neuroendocrine carcinoma of the prostate (SCNECP) is a rare, aggressive subtype of prostate carcinoma. Most SCNECP arise from conventional prostate adenocarcinoma (CPAC) treated with androgen depriv...

    Authors: Phoenix D. Bell, Aaron R. Huber and Diana Agostini-Vulaj

    Citation: Diagnostic Pathology 2021 16:35

    Content type: Case Report

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  33. Oral squamous cell carcinoma (OSCC) is the most relevant malignant neoplasm among all head and neck tumours due to its high prevalence and unfavourable prognosis. Tumour invasion and metastasis that affect pro...

    Authors: Geovanni Pereira Mitre, Karolyny Martins Balbinot, André Luis Ribeiro Ribeiro, Maria Sueli da Silva Kataoka, Sérgio de Melo Alves Júnior and João de Jesus Viana Pinheiro

    Citation: Diagnostic Pathology 2021 16:33

    Content type: Research

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  34. Solitary Fibrous Tumor (SFT) is a distinct soft tissue neoplasm associated with NAB2-STAT6 gene fusion. It can involve a number of anatomic sites and exhibits a wide spectrum of histological features.

    Authors: Muhammad Usman Tariq, Nasir Ud Din, Jamshid Abdul-Ghafar and Yong-Koo Park

    Citation: Diagnostic Pathology 2021 16:32

    Content type: Review

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  36. Nonsense mutation or inactivation of SMARCA4 (BRG1) is associated with a monomorphic undifferentiated histological appearance in tumors at different sites. The association between SMARCA4 alteration and undiff...

    Authors: Huanli Duan, Wei Gao, Leiming Wang, Feng Cao and Lianghong Teng

    Citation: Diagnostic Pathology 2021 16:30

    Content type: Case Report

    Published on:

  37. Primary hepatic mucoepidermoid carcinoma (HMEC) is extremely rare and the molecular etiology is still unknown. The CRTC1-MAML2 fusion gene was previously detected in a primary HMEC, which is often associated with...

    Authors: Ping Hou, Xiaoyan Su, Wei Cao, Liping Xu, Rongguiyi Zhang, Zhihao Huang, Jiakun Wang, Lixiang Li, Linquan Wu and Wenjun Liao

    Citation: Diagnostic Pathology 2021 16:29

    Content type: Research

    Published on:

  38. This study aimed to investigate the association between clinicopathologic factors, mesothelin, and cancer antigen (CA) 125 in endometrial carcinoma.

    Authors: Soichiro Kakimoto, Morikazu Miyamoto, Takahiro Einama, Yasuhiro Takihata, Hiroko Matsuura, Hideki Iwahashi, Hiroki Ishibashi, Takahiro Sakamoto, Taira Hada, Jin Suminokura, Tsubasa Ito, Rie Suzuki, Ayako Suzuki and Masashi Takano

    Citation: Diagnostic Pathology 2021 16:28

    Content type: Research

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  40. TWIST1 and CD105, which contribute to tumor malignancy, are overexpressed in cancers. Accordingly, TWIST1 enhances epithelial-to-mesenchymal transition (EMT) and promotes the formation of cancer stem cells (CS...

    Authors: Fahimeh Fattahi, Leili Saeednejad Zanjani, Somayeh Vafaei, Zohreh Habibi Shams, Jafar Kiani, Marzieh Naseri, Elmira Gheytanchi and Zahra Madjd

    Citation: Diagnostic Pathology 2021 16:26

    Content type: Research

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  41. Fine-needle aspiration (FNA) is a frequently utilized method for the diagnosis of thyroid nodules. Although the technique has clear advantages, the injury caused by the aspiration needle can induce various his...

    Authors: Woo Sung Moon, Myoung Jae Kang, Hyun Jo Youn and Kyoung Min Kim

    Citation: Diagnostic Pathology 2021 16:25

    Content type: Case Report

    Published on:

  42. The role of Artificial intelligence (AI) which is defined as the ability of computers to perform tasks that normally require human intelligence is constantly expanding. Medicine was slow to embrace AI. However...

    Authors: Zubair Ahmad, Shabina Rahim, Maha Zubair and Jamshid Abdul-Ghafar

    Citation: Diagnostic Pathology 2021 16:24

    Content type: Review

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  43. Kaposiform Hemangioendothelioma (KHE) is a rare vascular tumor of intermediate malignant potential which shows locally aggressive growth but only rarely metastasizes. It is mostly considered to be a tumor of p...

    Authors: Qurratulain Chundriger, Muhammad Usman Tariq, Jamshid Abdul-Ghafar, Arsalan Ahmed and Nasir Ud Din

    Citation: Diagnostic Pathology 2021 16:23

    Content type: Research

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  44. Sialadenoma papilliferum (SP) is an extremely rare benign neoplasm of salivary glands. To explore and define the clinicopathological features of SP, we retrospectively analyzed 89 cases previously reported and...

    Authors: Shuai Chen, Jie Peng, Chuantao Yuan, Lin Sun, Renya Zhang and Yan Sun

    Citation: Diagnostic Pathology 2021 16:22

    Content type: Research

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  45. In lung cancer management, differential diagnosis between multiple primary lung cancer (MPLC) and intrapulmonary metastasis (IMP) is a critical point that is of direct therapeutic and clinical importance. Howe...

    Authors: Changjiang Liu, Chengang Liu, Xiao Zou, Lin Shao, Ying Sun and Yang Guo

    Citation: Diagnostic Pathology 2021 16:21

    Content type: Case Report

    Published on:

  46. Making the distinction between primary mucinous and metastatic ovarian tumors is often difficult, especially in tumors with a primary source from the gastrointestinal tract, pancreas and biliary tree. The aim ...

    Authors: Pavel Dundr, Naveena Singh, Barbora Nožičková, Kristýna Němejcová, Michaela Bártů and Ivana Stružinská

    Citation: Diagnostic Pathology 2021 16:20

    Content type: Review

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  47. Immunohistochemistry (IHC) remains the gold standard for the diagnosis of pathological diseases. This technique has been supporting pathologists in making precise decisions regarding differential diagnosis and...

    Authors: Yosep Chong, Nishant Thakur, Ji Young Lee, Gyoyeon Hwang, Myungjin Choi, Yejin Kim, Hwanjo Yu and Mee Yon Cho

    Citation: Diagnostic Pathology 2021 16:19

    Content type: Research

    Published on:

  48. Metastases are common in non-cirrhotic livers but are considered unlikely in the setting of cirrhosis. However, the degree of fibrosis in cirrhosis may vary; thus metastases may still access the liver vasculat...

    Authors: Zaid Mahdi, Mark G. Ettel, Raul S. Gonzalez, John Hart, Lindsay Alpert, Jiayun Fang, Natalia Liu, Suntrea T. Hammer, Nicole Panarelli, Jerome Cheng, Joel K. Greenson, Paul E. Swanson and Maria Westerhoff

    Citation: Diagnostic Pathology 2021 16:18

    Content type: Research

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  49. Patients with head and neck squamous cell carcinoma (HNSCC) can develop lung squamous cell carcinoma (LuSCC), which could be the second primary tumor or HNSCC metastasis. Morphologically it is difficult to dis...

    Authors: Maja Šutić, Jurica Baranašić, Lana Kovač Bilić, Mario Bilić, Antonija Jakovčević, Luka Brčić, Sven Seiwerth, Marko Jakopović, Miroslav Samaržija, Ulrich Zechner and Jelena Knežević

    Citation: Diagnostic Pathology 2021 16:17

    Content type: Short report

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  50. To date, very few studies on clinical-histopathological correlations of cutaneous disorders associated with COVID-19 have been conducted.

    Authors: Angela Patrì, Maria Vargas, Pasquale Buonanno, Maria Carmela Annunziata, Daniela Russo, Stefania Staibano, Giuseppe Servillo and Gabriella Fabbrocini

    Citation: Diagnostic Pathology 2021 16:16

    Content type: Case Report

    Published on:

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