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COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times.  Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

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  1. The prognosis of patients with metastatic melanomas is extremely heterogeneous. Therefore, identifying high-risk subgroups by using innovative prediction models would help to improve selection of appropriate m...

    Authors: Rongyi Chen, Guoxue Zhang, Ying Zhou, Nan Li and Jiaxi Lin
    Citation: Diagnostic Pathology 2014 9:155
    Content type: Research Published on:

  2. Numerous studies examining the relationship between CD44 expression and prognostic impact in patients with osteosarcoma have yielded inconclusive results. The aim of this meta-analysis was carried out to inves...

    Authors: Yu Liu, Yongwei Wu, Sanjun Gu, Zhenzhong Sun, Yongjun Rui, Jianbing Wang, Yao Lu, Haifeng Li, Kelin Xu and Peng Sheng
    Citation: Diagnostic Pathology 2014 9:140
    Content type: Research Published on:

  3. The PIK3CA gene mutation was found to associate with prognosis and might affect molecular targeted therapy in esophageal carcinoma (EC). The aim of this study is to compare different methods for analyzing the PIK...

    Authors: Zizhen Ming, Dongxian Jiang, Qin Hu, Xiaojing Li, Jie Huang, Yifan Xu, Yalan Liu, Chen Xu, Xiuguo Hua and Yingyong Hou
    Citation: Diagnostic Pathology 2014 9:153
    Content type: Research Published on:

  4. Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and as a result, can form concentrically laminated electron dense spironolactone body inclusions within the adrenal gland. Spiro...

    Authors: Kishan A Patel, Edward P Calomeni, Tibor Nadasdy and Debra L Zynger
    Citation: Diagnostic Pathology 2014 9:147
    Content type: Research Published on:

  5. Anastomosing hemangioma, a benign vascular neoplasm histologically simulating angiosarcoma, is newly recognized and has been described primarily in the genitourinary tract. Here, we present a case of renal ana...

    Authors: Li-Li Tao, Yi Dai, Weihua Yin and Joan Chen
    Citation: Diagnostic Pathology 2014 9:159
    Content type: Case Report Published on:

  6. MicroRNAs (miRNAs) are short, non-coding RNAs that negatively regulate target genes. A single nucleotide polymorphism (SNP) in a miRNA sequence may alter miRNA expression and/or maturation, which was proposed ...

    Authors: Zaiqiu Wang, Xiaoli Sun, Yeli Wang, Xiaofang Liu, Yuanjie Xuan and Sanyuan Hu
    Citation: Diagnostic Pathology 2014 9:146
    Content type: Research Published on:

  7. Malignant adenomyoepithelioma and adenoid cystic carcinoma are both rare malignant epithelial-myoepithelial tumors of the breast. We report a very rare case with a malignant adenomyoepithelioma combining with ...

    Authors: Ying Yang, Yanmei Wang, Jinsong He, Guoqing Pan, Xiaoyu Tuo, Aimei Jiang and Li Bian
    Citation: Diagnostic Pathology 2014 9:148
    Content type: Case Report Published on:

  8. Despite great improvement in the surgical treatment and adjunctive therapy for oral squamous cell carcinoma (OSCC), prognosis remains dismal in advanced cases. Regional metastatic disease is known to reduce re...

    Authors: Partheeban Balasundaram, Manoj Kumar Singh, Amit Kumar Dinda, Alok Thakar and Rajni Yadav
    Citation: Diagnostic Pathology 2014 9:145
    Content type: Research Published on:

  9. Detection of B cell clonality is useful for assisting in the diagnosis of B cell lymphomas. Clonality assessment can be accomplished through evaluation of KAPPA and LAMBDA light chain expression. Currently, only ...

    Authors: Lisa M Rimsza, William A Day, Sarah McGinn, Anne Pedata, Yasodha Natkunam, Roger Warnke, James R Cook, Teresa Marafioti and Thomas M Grogan
    Citation: Diagnostic Pathology 2014 9:144
    Content type: Methodology Published on:

  10. A case of an unusual unilocular cystic lesion of diameter 7 cm located retroperitoneally in the pelvis in close connection to the right adnexa of a 61 year-old woman is presented. Macroscopically, the lesion h...

    Authors: Dariusz Adamek, Carina Jägers, Maria Hejnold, Robert Jach and Bartlomiej Galarowicz
    Citation: Diagnostic Pathology 2014 9:150
    Content type: Letter to the Editor Published on:

  11. Perivascular epithelioid cell tumors (PEComas) encompass a group of rare mesenchymal neoplasms, which typically have a perivascular location with dual melanocytic and muscular differentiation. They are found i...

    Authors: Hassania Ameurtesse, Laïla Chbani, Amal Bennani, Imane Toughrai, Nouhad Beggui, Imane Kamaoui, Hinde Elfatemi, Taoufik Harmouch and Afaf Amarti
    Citation: Diagnostic Pathology 2014 9:149
    Content type: Case Report Published on:

  12. Many studies have demonstrated that chemoradiotherapy followed by surgery (CRTS) prolongs the 5-year survival rate of resectable esophageal carcinoma patients. However, the effect of CRTS on postoperative comp...

    Authors: Jiaying Deng, Chunyu Wang, Mingqiong Xiang, Fatao Liu, Yun Liu and Kuaile Zhao
    Citation: Diagnostic Pathology 2014 9:151
    Content type: Research Published on:

  13. Metaplastic breast carcinoma is a rare entity of breast cancer expressing epithelial and/or mesenchymal tissue within the same tumor. The aim of this study is to evaluate the clinicopathological features of me...

    Authors: Fadwa J Altaf, Ghadeer A Mokhtar, Eman Emam, Rana Y Bokhary, Najlaa Bin Mahfouz, Samia Al Amoudi and Zuhoor K AL-Gaithy
    Citation: Diagnostic Pathology 2014 9:139
    Content type: Research Published on:

  14. TAZ is a downstream agent of Hippo signal pathway. β-catenin is a cell adhesion molecule associated with the invasion and metastasis of carcinomas as well as a critical component of Wnt pathway. TAZ and β-cate...

    Authors: Lidan Sun, Fei Chen, Wenna Shi, Lei Qi, Zhongmei Zhao and Jianping Zhang
    Citation: Diagnostic Pathology 2014 9:125
    Content type: Research Published on:

  15. Inflammatory myofibroblastic tumors (IMTs) mainly occur in children and young adults, usually in the first two decades of life. IMT-type tumors belong to neoplasms of an intermediate biologic potential with co...

    Authors: Zuzanna Dobrosz, Janusz Ryś, Piotr Paleń, Paweł Właszczuk and Marek Ciepiela
    Citation: Diagnostic Pathology 2014 9:138
    Content type: Case Report Published on:

  16. Overexpression of microRNA-182 (miR-182) is found in various human cancers, including non-small cell lung cancer (NSCLC). Our aim is to investigate the association of miR-182 expression with the sensitivity of...

    Authors: Fang-ling Ning, Feng Wang, Mian-li Li, Ze-shun Yu, Yan-zhang Hao and Shao-shui Chen
    Citation: Diagnostic Pathology 2014 9:143
    Content type: Research Published on:

  17. Morphine has been widely used as a clinical anesthetic and analgesic. However, abuse of morphine might result in psychological and physiological dependence. Previous studies have indicated that memory mechanis...

    Authors: Junyi Ye, Zhaoyang Yang, Candong Li, Meimei Cai, Daizhan Zhou, Qin Zhang, Yiming Wei, Ting Wang and Yun Liu
    Citation: Diagnostic Pathology 2014 9:142
    Content type: Research Published on:

  18. Glial scar formation is a common histopathological feature of traumatic brain injury (TBI). Astrogliosis and expression of transforming growth factor beta (TGF-β) are key components of scar formation and blood...

    Authors: Yuqi Liu, Zongwei Liu, Xiaoming Li, Bangwei Luo, Jian Xiong, Woting Gan, Man Jiang, Zhiyuan Zhang, Hermann J Schluesener and Zhiren Zhang
    Citation: Diagnostic Pathology 2014 9:141
    Content type: Research Published on:

  20. The effects of fascin on cell invasiveness involve changes in cell motility and matrix metalloproteinase-9 (MMP-9) activity. Previous studies on the prognostic value of fascin and MMP-9 in breast carcinoma rev...

    Authors: Nermeen Salah Youssef and Sarah Adel Hakim
    Citation: Diagnostic Pathology 2014 9:136
    Content type: Research Published on:

  21. Hepatocellular carcinoma (HCC) is regarded as one of the most common malignancies and among the leading causes of cancer death among the whole world. The most urgent needs are to find sensitive markers for ear...

    Authors: Zhu-qing Zhang, Hua Meng, Nan Wang, Li-na Liang, Li-na Liu, Shu-ming Lu and Yong Luan
    Citation: Diagnostic Pathology 2014 9:135
    Content type: Research Published on:

  22. A number of studies have examined the association between interleukin-6 (IL-6) rs1800796 polymorphism and risk of lung cancer but revealed inconsistent results. The aim of this study was to clarify the associatio...

    Authors: Weihua Wang, Jie Chen, Feng Zhao, Burong Zhang and Hongsheng Yu
    Citation: Diagnostic Pathology 2014 9:134
    Content type: Research Published on:

  23. This study aimed to investigate the clinical significance of contrast enhanced ultrasound (CEUS) in diagnosis of benign prostatic hyperplasia (BPH) through comparing CEUS parameters between BPH and normal person.

    Authors: Jingfang Shi, Xiaohua Yin, Rong Xu, Yingchun Wang, Lin Jin and Weiwei Gao
    Citation: Diagnostic Pathology 2014 9:133
    Content type: Research Published on:

    The Retraction Note to this article has been published in Diagnostic Pathology 2015 10:10

  24. Central nervous system (CNS) tumors are the most common solid tumors that occur in children, however there were few big-data follow-up analysis published in China. Overexpression of epidermal growth factor rec...

    Authors: Weidong Liu, Shigang Zhang, Liyong Zhang, Qingke Cui, Jiyue Wang, Ting Gui and Qi Pang
    Citation: Diagnostic Pathology 2014 9:132
    Content type: Research Published on:

  25. Epithelioid hemangioendothelioma is a malignant, often indolent vascular tumor which occurs at various anatomic sites. Based on a reciprocal translocation t (1;3)(p36;q25), a consistent WWTR1-CAMTA1 fusion gene h...

    Authors: Uta Flucke, Rob JC Vogels, Nicolas de Saint Aubain Somerhausen, David H Creytens, Robert G Riedl, Joost M van Gorp, Anya N Milne, Clement J Huysentruyt, Marian AJ Verdijk, Monique M van Asseldonk, Albert JH Suurmeijer, Johannes Bras, Gabriele Palmedo, Patricia JTA Groenen and Thomas Mentzel
    Citation: Diagnostic Pathology 2014 9:131
    Content type: Research Published on:

  26. Type 2 diabetes mellitus (T2DM) is a chronic incurable disease associated with multi-systemic complications. The chronic complications related to T2DM induce growing burden to the national health system. Diabe...

    Authors: Chun Zhao, Weifang Wang, Ding Xu, Hui Li, Min Li and Fang Wang
    Citation: Diagnostic Pathology 2014 9:130
    Content type: Research Published on:

  27. Rheumatoid arthritis (RA) is a severe chronic immune mediated inflammatory disease that has been shown to be associated with human leukocyte antigen (HLA) loci. The transporter associated with antigen processi...

    Authors: Dongjun Dai, Yong Chen, Ping Ru, Xingyu Zhou, Jianmin Tao, Huadan Ye, Qingxiao Hong, Linlin Tang, Guanghui Pan, Danfeng Lin, Qiongyao Gong, Yuelong Lv, Leiting Xu and Shiwei Duan
    Citation: Diagnostic Pathology 2014 9:129
    Content type: Research Published on:

  28. Metastatic spread of tumor through lymphatic vasculature is an important adverse prognostic factor in a variety of human cancer and tumor lymphangiogenesis requires the interplay of several growth factors. Pla...

    Authors: Jiannan Liu, Chuanyong Liu, Liyun Qiu, Juan Li, Pei Zhang and Yuping Sun
    Citation: Diagnostic Pathology 2014 9:128
    Content type: Research Published on:

  29. Adult intussusception is a rare but challenging condition. Preoperative diagnosis is frequently missed or delayed because of nonspecific or sub-acute symptoms.

    Authors: Kenneth M Joyce, Peadar S Waters, Ronan M Waldron, Iqbal Khan, Zolt S Orosz, Tamas Németh and Kevin Barry
    Citation: Diagnostic Pathology 2014 9:127
    Content type: Case Report Published on:

  30. Immunohistochemical staining for mismatch repair proteins is efficient and widely used to identify mismatch repair defective tumors. The tumors typically show uniform and widespread loss of MMR protein stainin...

    Authors: Patrick Joost, Nynke Veurink, Susanne Holck, Louise Klarskov, Anders Bojesen, Maria Harbo, Bo Baldetorp, Eva Rambech and Mef Nilbert
    Citation: Diagnostic Pathology 2014 9:126
    Content type: Research Published on:

  31. T-cell lymphoblastic lymphoma comprises approximately 85-90% of all lymphoblastic lymphomas. It often arises as a mediastinal mass, and with bone marrow involvement. Presentation at other sites without nodal o...

    Authors: Maria R Ambrosio, Monica Onorati, Bruno J Rocca, Alessandro Ginori, Giuseppe Lobello, Guido Petracco, Alessandro Davide Videtta, Franca Di Nuovo, Rosa Santopietro and Stefano Lazzi
    Citation: Diagnostic Pathology 2014 9:124
    Content type: Case Report Published on:

  32. Bone morphogenetic protein 2 (BMP-2) is a member of the TGF-β superfamily that is closely correlated with many malignancies, particularly lung cancer. However, the effects of silenced BMP-2 on lung cancer cell pr...

    Authors: Heying Chu, Hailan Luo, Huaqi Wang, Xiaonan Chen, Ping Li, Yong Bai, Furui Zhang, Ruirui Cheng, Shanshan Chen, Yuanyuan Wang, Guoqiang Zhao and Guojun Zhang
    Citation: Diagnostic Pathology 2014 9:123
    Content type: Research Published on:

  34. This study aimed to assess inter-observer variability between the original diagnostic reports and later review by a specialist in breast pathology considering lobular neoplasias (LN), columnar cell lesions (CC...

    Authors: Douglas S Gomes, Simone S Porto, Débora Balabram and Helenice Gobbi
    Citation: Diagnostic Pathology 2014 9:121
    Content type: Research Published on:

  35. Published studies investigating the association between XPC Lys939Gln polymorphism and colorectal cancer (CRC) risk reported inconclusive results. We performed a meta-analysis to derive a precise estimation of th...

    Authors: Qiliu Peng, Xianjun Lao, Weizhong Tang, Zhiping Chen, Ruolin Li, Xue Qin and Shan Li
    Citation: Diagnostic Pathology 2014 9:120
    Content type: Review Published on:

  36. Breast cancer is a heterogeneous disease consisting of different subtypes. Trichorhinophalangeal syndrome type 1 (TRPS1) gene, a GATA-type transcription factor, has been found to be highly expressed in breast can...

    Authors: Peng Su, Jing Hu, Hui Zhang, Ming Jia, Weiwei Li, Xuanxuan Jing and Gengyin Zhou
    Citation: Diagnostic Pathology 2014 9:119
    Content type: Research Published on:

  37. Ki67 is currently the proliferation biomarker of choice, with both prognostic and predictive value in breast cancer. A lack of consensus regarding Ki67 use in pre-analytical, analytical and post-analytical pra...

    Authors: Quinci Romero, Pär-Ola Bendahl, Mårten Fernö, Dorthe Grabau and Signe Borgquist
    Citation: Diagnostic Pathology 2014 9:118
    Content type: Research Published on:

  38. Cardiac tumours are relatively rare and are difficult to diagnose merely with imaging techniques. We demonstrated an unusual case of left atrial myxoma, displaying the successful detection by positron emission...

    Authors: Yukio Okazaki, Sohsuke Yamada, Shohei Kitada, Iwao Matsunaga, Eijirou Nogami, Teruo Watanabe, Yasuyuki Sasaguri, Yutaka Honma and Tsuyoshi Itou
    Citation: Diagnostic Pathology 2014 9:117
    Content type: Letter to the Editor Published on:

  39. CASTLE (Carcinoma showing thymus-like elements) is a rare malignant neoplasm of the thyroid resembling lymphoepithelioma-like and squamous cell carcinoma of the thymus with different biological behaviour and a...

    Authors: Lothar Veits, Rupert Schupfner, Petra Hufnagel, Roland Penzel, Jens Freitag, Philipp Ströbel, Michael A Kern, Sören Schröder, Nikolaus Neuhold, Kurt W Schmid, Peter Schirmacher, Arndt Hartmann and Ralf J Rieker
    Citation: Diagnostic Pathology 2014 9:116
    Content type: Research Published on:

  40. Rosai-Dorfman disease (RDD) involving the cardiovascular system is extremely rare; to our knowledge, there are only 9 cases in the literature. Here, a case of a 60-year-old male with RDD involving the right at...

    Authors: Yalan Bi, Zhen Huo, Yunxiao Meng, Huanwen Wu, Jingbo Yan, Yuan Zhou, Xingrong Liu, Lan Song and Zhaohui Lu
    Citation: Diagnostic Pathology 2014 9:115
    Content type: Letter to the Editor Published on:

  41. Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on heart function and survival. Despite already available digital methods, the pathologist’s visual score is still widely consi...

    Authors: Dainius Daunoravicius, Justinas Besusparis, Edvardas Zurauskas, Aida Laurinaviciene, Daiva Bironaite, Sabine Pankuweit, Benoit Plancoulaine, Paulette Herlin, Julius Bogomolovas, Virginija Grabauskiene and Arvydas Laurinavicius
    Citation: Diagnostic Pathology 2014 9:114
    Content type: Research Published on:

  44. We describe a case of giant cell tumor of the proximal tibia with skip bone metastases of the ipsilateral femur in a 20-year-old man. After the neoadjuvant treatment with denosumab, plain radiographs and compu...

    Authors: Michiyuki Hakozaki, Takahiro Tajino, Hitoshi Yamada, Osamu Hasegawa, Kazuhiro Tasaki, Kazuo Watanabe and Shinichi Konno
    Citation: Diagnostic Pathology 2014 9:111
    Content type: Letter to the Editor Published on:

  45. Squamous cell carcinomas (SCCs) are uncommon, high-grade tumors, predominantly composed of round cells in the prepuce. The aim of this study is to better define the clinicopathologic features of this neoplasm.

    Authors: Javad Yaghoobi Yeganeh Manesh, Radmehr Shafiee, Ali Mohammad Bahrami, Mehdi Pourzaer, Maryam Pourzaer, Behnam Pedram, Javad Javanbakht, Aram Mokarizadeh and Farshid Khadivar
    Citation: Diagnostic Pathology 2014 9:999
    Content type: Case Report Published on:

    The Retraction Note to this article has been published in Diagnostic Pathology 2016 11:115

  46. Bilateral ovarian metastasis from invasive squamous cell carcinoma of the cervix is a rare phenomenon with very few clinically significant cases described in the literature. Ovarian metastases when present are...

    Authors: Sunil Jaiman, Kameswari Surampudi, Sirisha Rao Gundabattula and Deepasha Garg
    Citation: Diagnostic Pathology 2014 9:109
    Content type: Case Report Published on:

  47. The base excision repair (BER) pathway removes DNA damage caused by ionizing radiation, reactive oxidative species and methylating agents. OGG1 and APE1 are two important genes in the BER pathway. Many epidemi...

    Authors: Qiliu Peng, Yu Lu, Xianjun Lao, Zhiping Chen, Ruolin Li, Jingzhe Sui, Xue Qin and Shan Li
    Citation: Diagnostic Pathology 2014 9:108
    Content type: Research Published on:

  48. Adult testicular granulosa cell tumors are rare sex cord- stromal tumors of which only 45 have been previously reported. As compared with their ovarian counterparts, these tumors may follow a more aggressive c...

    Authors: Thomas EO Schubert, Robert Stoehr, Arndt Hartmann, Sabrina Schöne, Mathias Löbelenz and Gregor Mikuz
    Citation: Diagnostic Pathology 2014 9:107
    Content type: Case Report Published on:
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Diagnostic Pathology

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